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    • 2. 发明申请
    • Tissue Dicing and Particle Separation Device
    • 组织切片和颗粒分离装置
    • US20110282372A1
    • 2011-11-17
    • US12777783
    • 2010-05-11
    • Joseph P. SchowalterPrasanna MalaviyaDavid A. WittFrederick E. Shelton, IV
    • Joseph P. SchowalterPrasanna MalaviyaDavid A. WittFrederick E. Shelton, IV
    • A61B17/32
    • C12M45/02
    • A tissue dicing and separation device comprises a housing having an interior that receives tissue for dicing and separation. The device includes a blade assembly connected to a motor and solenoid. The solenoid reciprocates the blade assembly while the motor clocks the blade assembly during each reciprocation cycle. This reciprocating and clocking action of the blade assembly dices and/or minces the tissue. The housing is filled with a fluid and then the blade assembly is continuously rotated to create a vortex within the housing. The vortex causes the diced tissue particles to separate by particle size. Outlets at different positions along the housing permit withdrawal of a slurry of fluid and tissue particles with the tissue particles having a desired size range. The obtained slurry may be used in conjunction with a fistula plug treatment device and method.
    • 组织切片和分离装置包括具有容纳组织用于切割和分离的内部的壳体。 该装置包括连接到电动机和螺线管的叶片组件。 在电动机在每个往复循环期间对叶片组件进行时钟时,螺线管使叶片组件往复运动。 叶片组件的这种往复运动和时钟作用切割和/或使组织变细。 壳体填充有流体,然后叶片组件被连续旋转以在壳体内产生涡流。 涡流使得切割的组织颗粒通过粒度分离。 沿着壳体的不同位置处的出口允许流体和组织颗粒的浆料与组织颗粒具有期望的尺寸范围。 所获得的浆液可以与瘘塞治疗装置和方法结合使用。
    • 3. 发明授权
    • Tissue processing system and method
    • 组织加工系统及方法
    • US08349255B2
    • 2013-01-08
    • US12777723
    • 2010-05-11
    • Joseph P. SchowalterPrasanna MalaviyaDavid A. WittFrederick E. Shelton, IV
    • Joseph P. SchowalterPrasanna MalaviyaDavid A. WittFrederick E. Shelton, IV
    • G01N21/00
    • C12M45/02Y10T436/2575
    • A tissue processing system includes a tray and a processing component. The processing component has teeth configured to dice, mince, and mix the tissue in the tray. In some versions, teeth of a rotary member mesh with teeth of a stationary member, such that the tissue is ground between the meshing teeth. The rotary member may be moved in an orbital path relative to the stationary member. In some versions, the teeth of two rotary members mesh together, and the rotary members are rotated in opposite directions to grind the tissue. The rotary members may also be alternatingly moved up and down to perform initial dicing on the tissue. Once the tissue has been processed, the tissue may then be used in a therapeutic manner, such as by being incorporated with a scaffold and then implanted in the same patient from whom the tissue was originally harvested.
    • 纸巾处理系统包括托盘和处理部件。 处理部件具有齿,其被配置成对托盘中的组织进行切割,切碎和混合。 在一些形式中,旋转构件的齿与固定构件的齿啮合,使得组织在啮合齿之间被磨削。 旋转构件可以相对于固定构件在轨道路径中移动。 在一些形式中,两个旋转构件的齿啮合在一起,并且旋转构件沿相反方向旋转以研磨组织。 旋转构件也可以交替地上下移动以对组织进行初始切割。 一旦已经处理了组织,则组合物可以以治疗方式使用,例如通过与支架结合,然后植入与最初收获组织的同一患者中。
    • 5. 发明申请
    • Tissue Processing System and Method
    • 组织加工系统与方法
    • US20110281350A1
    • 2011-11-17
    • US12777723
    • 2010-05-11
    • Joseph P. SchowalterPrasanna MalaviyaDavid A. WittFrederick E. Shelton, IV
    • Joseph P. SchowalterPrasanna MalaviyaDavid A. WittFrederick E. Shelton, IV
    • C12N5/071C12M1/00
    • C12M45/02Y10T436/2575
    • A tissue processing system includes a tray and a processing component. The processing component has teeth configured to dice, mince, and mix the tissue in the tray. In some versions, teeth of a rotary member mesh with teeth of a stationary member, such that the tissue is ground between the meshing teeth. The rotary member may be moved in an orbital path relative to the stationary member. In some versions, the teeth of two rotary members mesh together, and the rotary members are rotated in opposite directions to grind the tissue. The rotary members may also be alternatingly moved up and down to perform initial dicing on the tissue. Once the tissue has been processed, the tissue may then be used in a therapeutic manner, such as by being incorporated with a scaffold and then implanted in the same patient from whom the tissue was originally harvested.
    • 纸巾处理系统包括托盘和处理部件。 处理部件具有齿,其被配置成对托盘中的组织进行切割,切碎和混合。 在一些形式中,旋转构件的齿与固定构件的齿啮合,使得组织在啮合齿之间被磨削。 旋转构件可以相对于固定构件在轨道路径中移动。 在一些形式中,两个旋转构件的齿啮合在一起,并且旋转构件沿相反方向旋转以研磨组织。 旋转构件也可以交替地上下移动以对组织进行初始切割。 一旦组织被处理,组织然后可以以治疗方式使用,例如通过与支架结合,然后植入与组织最初收获的同一患者中。
    • 8. 发明授权
    • Tissue dicing and particle separation device
    • 组织切片和颗粒分离装置
    • US08286899B2
    • 2012-10-16
    • US12777783
    • 2010-05-11
    • Joseph P. SchowalterPrasanna MalaviyaDavid A. WittFrederick E. Shelton, IV
    • Joseph P. SchowalterPrasanna MalaviyaDavid A. WittFrederick E. Shelton, IV
    • B02C19/00
    • C12M45/02
    • A tissue dicing and separation device comprises a housing having an interior that receives tissue for dicing and separation. The device includes a blade assembly connected to a motor and solenoid. The solenoid reciprocates the blade assembly while the motor clocks the blade assembly during each reciprocation cycle. This reciprocating and clocking action of the blade assembly dices and/or minces the tissue. The housing is filled with a fluid and then the blade assembly is continuously rotated to create a vortex within the housing. The vortex causes the diced tissue particles to separate by particle size. Outlets at different positions along the housing permit withdrawal of a slurry of fluid and tissue particles with the tissue particles having a desired size range. The obtained slurry may be used in conjunction with a fistula plug treatment device and method.
    • 组织切片和分离装置包括具有容纳组织用于切割和分离的内部的壳体。 该装置包括连接到电动机和螺线管的叶片组件。 在电动机在每个往复循环期间对叶片组件进行时钟时,螺线管使叶片组件往复运动。 叶片组件的这种往复运动和时钟作用切割和/或使组织变细。 壳体填充有流体,然后叶片组件被连续旋转以在壳体内产生涡流。 涡流使得切割的组织颗粒通过粒度分离。 沿着壳体的不同位置处的出口允许流体和组织颗粒的浆料与组织颗粒具有期望的尺寸范围。 所获得的浆液可以与瘘塞治疗装置和方法结合使用。