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1. 发明授权

US08478384B2 Intravascular optical coherence tomography system with pressure monitoring interface and accessories 有权
标题翻译：血管内光学相干断层扫描系统具有压力监测界面和附件
公开(公告)号：US08478384B2
公开(公告)日：2013-07-02
申请号：US12689724
申请日：2010-01-19
申请人： Joseph M. Schmitt , Christopher Petroff
发明人： Joseph M. Schmitt , Christopher Petroff
IPC分类号： A61B5/00
CPC分类号： A61B5/02154 , A61B5/0066 , A61B5/0075 , A61B5/0084 , A61B5/02007 , A61B5/0215 , A61B5/6852 , A61B5/742
摘要： An optical coherence tomography system and method with integrated pressure measurement. In one embodiment the system includes an interferometer including: a wavelength swept laser; a source arm in communication with the wavelength swept laser; a reference arm in communication with a reference reflector; a first photodetector having a signal output; a detector arm in communication with the first photodetector, a probe interface; a sample arm in communication with a first optical connector of the probe interface; an acquisition and display system comprising: an A/D converter having a signal input in communication with the first photodetector signal output and a signal output; a processor system in communication with the A/D converter signal output; and a display in communication with the processor system; and a probe comprising a pressure sensor and configured for connection to the first optical connector of the probe interface, wherein the pressure transducer comprises an optical pressure transducer.
摘要翻译：光学相干断层扫描系统和集成压力测量方法。在一个实施例中，系统包括干涉仪，包括：波长扫描激光; 与波长扫描激光器通信的源臂; 与参考反射器连通的参考臂; 具有信号输出的第一光电检测器; 与第一光电检测器连通的检测器臂，探针接口; 与所述探针接口的第一光学连接器连通的样品臂; 一种采集和显示系统，包括：具有与第一光电检测器信号输出通信的信号输入的信号输出的A / D转换器; 与A / D转换器信号输出通信的处理器系统; 以及与处理器系统通信的显示器; 以及探针，其包括压力传感器并且被配置为连接到所述探针接口的所述第一光学连接器，其中所述压力传感器包括光学压力传感器。

2. 发明申请

US20140187929A1 Intravascular Optical Coherence Tomography System with Pressure Monitoring Interface and Accessories 审中-公开
标题翻译：血管内光学相干断层扫描系统与压力监测接口和附件
公开(公告)号：US20140187929A1
公开(公告)日：2014-07-03
申请号：US14151340
申请日：2014-01-09
申请人： Joseph M. Schmitt , Christopher Petroff
发明人： Joseph M. Schmitt , Christopher Petroff
IPC分类号： A61B5/0215 , A61B5/00
CPC分类号： A61B5/02154 , A61B5/0066 , A61B5/0075 , A61B5/0084 , A61B5/02007 , A61B5/0215 , A61B5/6852 , A61B5/742
摘要： An optical coherence tomography system and method with integrated pressure measurement. In one embodiment the system includes an interferometer including: a wavelength swept laser; a source arm in communication with the wavelength swept laser; a reference arm in communication with a reference reflector; a first photodetector having a signal output; a detector arm in communication with the first photodetector, a probe interface; a sample arm in communication with a first optical connector of the probe interface; an acquisition and display system comprising: an A/D converter having a signal input in communication with the first photodetector signal output and a signal output; a processor system in communication with the A/D converter signal output; and a display in communication with the processor system; and a probe comprising a pressure sensor and configured for connection to the first optical connector of the probe interface, wherein the pressure transducer comprises an optical pressure transducer.
摘要翻译：光学相干断层扫描系统和集成压力测量方法。在一个实施例中，系统包括干涉仪，包括：波长扫描激光; 与波长扫描激光器通信的源臂; 与参考反射器连通的参考臂; 具有信号输出的第一光电检测器; 与第一光电检测器连通的检测器臂，探针接口; 与所述探针接口的第一光学连接器连通的样品臂; 一种采集和显示系统，包括：具有与第一光电检测器信号输出通信的信号输入的信号输出的A / D转换器; 与A / D转换器信号输出通信的处理器系统; 以及与处理器系统通信的显示器; 以及探针，其包括压力传感器并且被配置为连接到所述探针接口的所述第一光学连接器，其中所述压力传感器包括光学压力传感器。

3. 发明申请

US20130072805A1 Lumen Morphology and Vascular Resistance Measurements Data Collection Systems, Apparatus and Methods 有权
标题翻译：流明形态和血管阻力测量数据收集系统，装置和方法
公开(公告)号：US20130072805A1
公开(公告)日：2013-03-21
申请号：US13617441
申请日：2012-09-14
申请人： Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
发明人： Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
IPC分类号： A61B5/00
CPC分类号： A61B5/0066 , A61B5/02007 , A61B5/6852 , A61B2034/102 , A61F2/82 , G06T7/0012 , G06T2200/24 , G06T2207/10016 , G06T2207/10101 , G06T2207/30101
摘要： A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
摘要翻译：一种自动定位在血管图像中的管腔边界在容器中的位置以及从测量血管直径的方法和装置。从容器的直径和估计的血流速度，然后确定许多临床显着的生理参数，并且生成各种用户显示关注。这些图像和参数的一个用途是帮助临床医生放置支架。在一个实施例中，该系统使用这些测量来允许临床医生模拟支架的放置并确定放置的影响。此外，从这些患者参数，然后执行各种患者治疗。

4. 发明申请

US20180344174A9 Lumen Morphology and Vascular Resistance Measurements Data Collection Systems, Apparatus and Methods 审中-公开
公开(公告)号：US20180344174A9
公开(公告)日：2018-12-06
申请号：US13796710
申请日：2013-03-12
申请人： Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
发明人： Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
IPC分类号： A61B5/02 , A61B5/00
CPC分类号： A61B5/02007 , A61B5/0066 , A61B5/0084
摘要： A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimate blood flow rate, a number of clinically significant physiological parameters are then determine and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

5. 发明申请

US20120238869A1 Intravascular Optical Coherence Tomography System with Pressure Monitoring Interface and Accessories 有权
标题翻译：血管内光学相干断层扫描系统与压力监测接口和附件
公开(公告)号：US20120238869A1
公开(公告)日：2012-09-20
申请号：US13484936
申请日：2012-05-31
申请人： Joseph M. Schmitt , Christopher Petroff
发明人： Joseph M. Schmitt , Christopher Petroff
IPC分类号： A61B6/00
CPC分类号： A61B5/02154 , A61B5/0066 , A61B5/0075 , A61B5/0084 , A61B5/02007 , A61B5/0215 , A61B5/6852 , A61B5/742
摘要： An optical coherence tomography system and method with integrated pressure measurement. In one embodiment the system includes an interferometer including: a wavelength swept laser; a source arm in communication with the wavelength swept laser; a reference arm in communication with a reference reflector; a first photodetector having a signal output; a detector arm in communication with the first photodetector, a probe interface; a sample arm in communication with a first optical connector of the probe interface; an acquisition and display system comprising: an A/D converter having a signal input in communication with the first photodetector signal output and a signal output; a processor system in communication with the A/D converter signal output; and a display in communication with the processor system; and a probe comprising a pressure sensor and configured for connection to the first optical connector of the probe interface, wherein the pressure transducer comprises an optical pressure transducer.
摘要翻译：光学相干断层扫描系统和集成压力测量方法。在一个实施例中，系统包括干涉仪，包括：波长扫描激光; 与波长扫描激光器通信的源臂; 与参考反射器连通的参考臂; 具有信号输出的第一光电检测器; 与第一光电检测器连通的检测器臂，探针接口; 与所述探针接口的第一光学连接器连通的样品臂; 一种采集和显示系统，包括：具有与第一光电检测器信号输出通信的信号输入的信号输出的A / D转换器; 与A / D转换器信号输出通信的处理器系统; 以及与处理器系统通信的显示器; 以及探针，其包括压力传感器并且被配置为连接到所述探针接口的所述第一光学连接器，其中所述压力传感器包括光学压力传感器。

6. 发明授权

US09138147B2 Lumen morphology image reconstruction based on the scan line data of OCT 有权
标题翻译：基于OCT扫描线数据的流明形态学图像重建
公开(公告)号：US09138147B2
公开(公告)日：2015-09-22
申请号：US12888347
申请日：2010-09-22
申请人： Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
发明人： Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
IPC分类号： A61B6/00 , A61B5/00 , A61B5/02 , G06T7/00 , G06K9/00 , A61B19/00 , A61F2/82
CPC分类号： A61B5/0066 , A61B5/02007 , A61B5/6852 , A61B2034/102 , A61F2/82 , G06T7/0012 , G06T2200/24 , G06T2207/10016 , G06T2207/10101 , G06T2207/30101
摘要： A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
摘要翻译：一种自动定位在血管图像中的管腔边界在容器中的位置以及从测量血管直径的方法和装置。从容器的直径和估计的血流速度，然后确定许多临床显着的生理参数，并且生成各种用户显示关注。这些图像和参数的一个用途是帮助临床医生放置支架。在一个实施例中，该系统使用这些测量来允许临床医生模拟支架的放置并确定放置的影响。此外，从这些患者参数，然后执行各种患者治疗。

7. 发明申请

US20140276011A1 Lumen Morphology and Vascular Resistance Measurements Data Collection Systems, Apparatus and Methods 审中-公开
标题翻译：流明形态和血管阻力测量数据采集系统，装置和方法
公开(公告)号：US20140276011A1
公开(公告)日：2014-09-18
申请号：US13796710
申请日：2013-03-12
申请人： Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
发明人： Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
IPC分类号： A61B5/02 , A61B5/00
CPC分类号： A61B5/02007 , A61B5/0066 , A61B5/0084
摘要： A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimate blood flow rate, a number of clinically significant physiological parameters are then determine and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
摘要翻译：一种自动定位在血管图像中的管腔边界在容器中的位置以及从测量血管直径的方法和装置。从容器的直径和估计血流速度，然后确定许多临床显着的生理参数，并且生成各种用户显示兴趣。这些图像和参数的一个用途是帮助临床医生放置支架。在一个实施例中，该系统使用这些测量来允许临床医生模拟支架的放置并确定放置的影响。此外，从这些患者参数，然后执行各种患者治疗。

8. 发明申请

US20110178413A1 INTRAVASCULAR OPTICAL COHERENCE TOMOGRAPHY SYSTEM WITH PRESSURE MONITORING INTERFACE AND ACCESSORIES 有权
标题翻译：具有压力监测界面和附件的血管光学相干系统
公开(公告)号：US20110178413A1
公开(公告)日：2011-07-21
申请号：US12689724
申请日：2010-01-19
申请人： Joseph M. Schmitt , Christopher Petroff
发明人： Joseph M. Schmitt , Christopher Petroff
IPC分类号： A61B6/00 , G01B11/02 , G01J3/45 , G01L11/02 , G02B6/00 , A61B5/02
CPC分类号： A61B5/02154 , A61B5/0066 , A61B5/0075 , A61B5/0084 , A61B5/02007 , A61B5/0215 , A61B5/6852 , A61B5/742
摘要： An optical coherence tomography system and method with integrated pressure measurement. In one embodiment the system includes an interferometer including: a wavelength swept laser; a source arm in communication with the wavelength swept laser; a reference arm in communication with a reference reflector; a first photodetector having a signal output; a detector arm in communication with the first photodetector, a probe interface; a sample arm in communication with a first optical connector of the probe interface; an acquisition and display system comprising: an A/D converter having a signal input in communication with the first photodetector signal output and a signal output; a processor system in communication with the A/D converter signal output; and a display in communication with the processor system; and a probe comprising a pressure sensor and configured for connection to the first optical connector of the probe interface, wherein the pressure transducer comprises an optical pressure transducer.
摘要翻译：光学相干断层扫描系统和集成压力测量方法。在一个实施例中，系统包括干涉仪，包括：波长扫描激光; 与波长扫描激光器通信的源臂; 与参考反射器连通的参考臂; 具有信号输出的第一光电检测器; 与第一光电检测器连通的检测器臂，探针接口; 与所述探针接口的第一光学连接器连通的样品臂; 一种采集和显示系统，包括：具有与第一光电检测器信号输出通信的信号输入的信号输出的A / D转换器; 与A / D转换器信号输出通信的处理器系统; 以及与处理器系统通信的显示器; 以及探针，其包括压力传感器并且被配置为连接到所述探针接口的所述第一光学连接器，其中所述压力传感器包括光学压力传感器。

9. 发明授权

US09572495B2 Optical coherence tomography lumen morphology and vascular resistance measurements methods for blood vessel evaluations 有权
标题翻译：光学相干断层扫描管腔形态和血管阻力测量方法进行血管评估
公开(公告)号：US09572495B2
公开(公告)日：2017-02-21
申请号：US13617441
申请日：2012-09-14
申请人： Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
发明人： Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
IPC分类号： A61B5/00 , A61B5/02 , G06T7/00 , A61F2/82
CPC分类号： A61B5/0066 , A61B5/02007 , A61B5/6852 , A61B2034/102 , A61F2/82 , G06T7/0012 , G06T2200/24 , G06T2207/10016 , G06T2207/10101 , G06T2207/30101
摘要： A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
摘要翻译：一种自动定位在血管图像中的管腔边界在容器中的位置以及从测量血管直径的方法和装置。从容器的直径和估计的血流速度，然后确定许多临床显着的生理参数，并且生成各种用户显示关注。这些图像和参数的一个用途是帮助临床医生放置支架。在一个实施例中，该系统使用这些测量来允许临床医生模拟支架的放置并确定放置的影响。此外，从这些患者参数，然后执行各种患者治疗。

10. 发明授权

US08676299B2 Method of determining pressure in a vessel as measured by an optical pressure transducer in an optical coherence tomography system 有权
标题翻译：在光学相干断层摄影系统中通过光学压力传感器测量的确定容器中的压力的方法
公开(公告)号：US08676299B2
公开(公告)日：2014-03-18
申请号：US13484936
申请日：2012-05-31
申请人： Joseph M. Schmitt , Christopher Petroff
发明人： Joseph M. Schmitt , Christopher Petroff
IPC分类号： A61B5/00
CPC分类号： A61B5/02154 , A61B5/0066 , A61B5/0075 , A61B5/0084 , A61B5/02007 , A61B5/0215 , A61B5/6852 , A61B5/742
摘要： An OCT system and method with integrated pressure measurement. In one embodiment, the system includes an interferometer; a wavelength swept laser; a source arm in communication with the wavelength swept laser; a reference arm in communication with a reference reflector; a first photoreceiver having a signal output; a detector arm in communication with the first photoreceiver, a probe interface; a sample arm in communication with a first optical connector of the probe interface; an acquisition and display system comprising: an A/D converter having a signal input in communication with the first photoreceiver signal output and a signal output; a processor system in communication with the A/D converter signal output; and a display in communication with the processor system; and a probe comprising a pressure sensor and configured for connection to the first optical connector of the probe interface, wherein the pressure transducer comprises an optical pressure transducer.
摘要翻译：具有集成压力测量的OCT系统和方法。在一个实施例中，系统包括干涉仪; 波长扫描激光; 与波长扫描激光器通信的源臂; 与参考反射器连通的参考臂; 具有信号输出的第一光接收器; 与第一光接收器通信的检测器臂，探针接口; 与所述探针接口的第一光学连接器连通的样品臂; 一种采集和显示系统，包括：具有与第一光接收器信号输出通信的信号输入和信号输出的A / D转换器; 与A / D转换器信号输出通信的处理器系统; 以及与处理器系统通信的显示器; 以及探针，其包括压力传感器并且被配置为连接到所述探针接口的所述第一光学连接器，其中所述压力传感器包括光学压力传感器。

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