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    • 1. 发明授权
    • Method of measuring cardiac related parameters non-invasively via the lung during spontaneous and controlled ventilation
    • 在自发和受控通气期间通过肺非侵入性测量心脏相关参数的方法
    • US08460202B2
    • 2013-06-11
    • US10545562
    • 2004-02-18
    • Joseph FisherDavid PreissTakafumi AsamiAlex VeselyEltan PrismanRon SomogyiSteve Iscoe
    • Joseph FisherDavid PreissTakafumi AsamiAlex VeselyEltan PrismanRon SomogyiSteve Iscoe
    • A61B5/08
    • A61B5/0205A61B5/083A61B5/14551A61B5/7225A61B5/7278A61M16/08A61M16/0833A61M16/085A61M16/0858A61M16/202A61M16/205A61M16/206A61M16/208A61M16/22
    • An apparatus to measure cardiac output (Q) and other parameters such as alveolar ventilation (VA), minute CO2 elimination from the lung (VCO2), minute oxygen consumption (VO2), oxygenated mixed venous partial pressure of CO2, (PvCO2-oxy), true mixed venous partial pressure of CO2(PvCO2), PaCO2, mixed venous oxygen saturation (SvO2), pulmonary shunt, and anatomical dead space, consisting of: a) a breathing circuit with characteristics that: i. on exhalation, exhaled gas is kept substantially separate from inhaled gas; ii. on inhalation, when VE is greater than FGS flow, the subject inhales FGS first and then inhales a gas that is substantially SGS, for the balance of inhalation; b) gas sensor means for monitoring gas concentrations at the patient-circuit interface c) a first gas set (FGS), and a second gas set (SGS), said second gas set which may comprise previously exhaled gases or exogenous gases or both d) a gas flow control means for controlling the rate of FGS flow into the breathing circuit e) means to identify phase of breathing, said means may consist of pressure sensors or analysis of signal generated by gas sensors or other means known to those skilled in the art; f) machine intelligence consisting of a computer or logic circuit capable of controlling the gas flow control means, receiving the output of the gas sensor means and means to identify phase of breathing, and performing the calculations for measuring cardiac output and other parameters as outlined in the disclosure.
    • 测量心输出量(Q)和其他参数如肺泡通气(VA),从肺中消除二氧化碳(VCO2),微量氧消耗(VO2),氧合混合静脉分压CO2(PvCO2-氧) ,真正的混合静脉分压二氧化碳(PvCO2),PaCO2,混合静脉血氧饱和度(SvO2),肺动脉分流和解剖死空间组成:a)具有以下特征的呼吸回路: 在呼气时,呼出气体与吸入气体基本分离; ii。 吸入时,当VE大于FGS流量时,受试者首先吸入FGS,然后吸入基本上为SGS的气体,用于吸入余量; b)用于监测患者 - 电路接口处的气体浓度的气体传感器装置c)第一气体组(FGS)和第二气体组(SGS),所述第二气体组可以包括先前呼出的气体或外来气体或二者 )用于控制FGS流入呼吸回路的速率的气体流量控制装置e)识别呼吸相位的装置,所述装置可包括压力传感器或由气体传感器产生的信号分析或本领域技术人员已知的其它装置 艺术; f)机器智能,包括能够控制气体流量控制装置的计算机或逻辑电路,接收气体传感器装置的输出和识别呼吸相位的装置,以及执行用于测量心输出量和其他参数的计算,如 披露。