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1. 发明申请

US20100280005A1 Renin Inhibitors 审中-公开
标题翻译：肾素抑制剂
公开(公告)号：US20100280005A1
公开(公告)日：2010-11-04
申请号：US12450620
申请日：2008-04-04
申请人： Jonh J. Baldwin , Salvacion Cacatian , David Claremon , Lawrence W. Dillard , Patrick T. Flaherty , Bahman Ghavimi-Alagha , John Gleason , Alexey V. Ishchenko , Brian Lawhorn , Gerard McGeehan , Jaclyn R. Patterson , Simon F. Semus , Robert D. Simpson , Suresh B. Singh , Colin Tice , Tritin Tran , Zhenrong Xu , Jing Yuan , Wei Zhao
发明人： Jonh J. Baldwin , Salvacion Cacatian , David Claremon , Lawrence W. Dillard , Patrick T. Flaherty , Bahman Ghavimi-Alagha , John Gleason , Alexey V. Ishchenko , Brian Lawhorn , Gerard McGeehan , Jaclyn R. Patterson , Simon F. Semus , Robert D. Simpson , Suresh B. Singh , Colin Tice , Tritin Tran , Zhenrong Xu , Jing Yuan , Wei Zhao
IPC分类号： A61K31/445 , C07D211/60 , C07D401/02 , C07D413/02 , A61K31/454 , A61K31/4545 , A61K31/4709 , A61K31/496 , A61K31/5377 , A61K31/5415 , A61K31/55 , A61K31/58 , A61P9/12
CPC分类号： C07D211/22 , C07D401/06
摘要： Disclosed are compounds of Formula I, wherein the R, R1, R2, R3, X, Y, A, Q, E, and G are defined herein. These compounds bind to aspartic proteases to inhibit their activity and are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also disclosed are methods of use of the compounds of Formula I for ameliorating or treating aspartic protease related disorders in a subject in need thereof.
摘要翻译：公开了式I的化合物，其中R，R 1，R 2，R 3，X，Y，A，Q，E和G如本文所定义。这些化合物与天冬氨酸蛋白酶结合以抑制其活性，并且可用于治疗或改善与天冬氨酸蛋白酶活性相关的疾病。还公开了使用式I化合物在有需要的受试者中改善或治疗天冬氨酸蛋白酶相关病症的方法。

2. 发明申请

US20080181719A1 ROTATING JOINT 审中-公开
标题翻译：旋转接头
公开(公告)号：US20080181719A1
公开(公告)日：2008-07-31
申请号：US11829522
申请日：2007-07-27
申请人： John Gleason , Reinhard Buhl , William Ryan
发明人： John Gleason , Reinhard Buhl , William Ryan
IPC分类号： F16C11/06
CPC分类号： F16C11/0614 , F16C11/0671 , F16C23/046 , F16C31/02 , Y10T403/32196
摘要： Disclosed is a component providing rotational, translational and angular movement to a shaft inserted therein. The component has a housing with a bearing aperture, the bearing aperture having an aperture axis, an inner concave surface and a placement ring surface. A combination joint including a hollow bearing and a placement ring are located at least partially within the bearing aperture. The hollow bearing has an outer convex surface adjacent to and at least partially in contact with the inner concave surface of the bearing aperture. The hollow bearing also has an aperture with a cylindrical inner surface. The placement ring has an outer surface adjacent to and at least partially in contact with the placement ring surface of the bearing aperture and has an inner concave bearing race surface adjacent to and at least partially in contact with the outer convex surface of the hollow bearing aperture. A sleeve with a sleeve axis can be located within the aperture of the hollow bearing and has an outer surface adjacent to and at least partially in contact with the cylindrical inner surface of the hollow bearing. The sleeve is slidable within the hollow bearing and the hollow bearing with the sleeve therein can rotate about the sleeve axis and tilt about the bearing aperture axis. In this manner, a component is provided that affords rotational, translational and angular movement to a shaft inserted therein. A seal can be included to protect the combination joint from dust, dirt, debris and the like.
摘要翻译：公开了向插入其中的轴提供旋转，平移和角运动的部件。该部件具有带轴承孔的壳体，轴承孔具有孔径轴线，内凹面和放置环表面。包括中空轴承和放置环的组合接头至少部分地位于轴承孔内。中空轴承具有与轴承孔的内凹面相邻且至少部分地接触的外凸表面。中空轴承还具有带有圆柱形内表面的孔。放置环具有与轴承孔的放置环表面相邻且至少部分地接触的外表面，并且具有与中空轴承孔的外凸表面相邻且至少部分地接触的内凹轴承座圈表面。具有套筒轴线的套筒可以位于中空轴承的孔内，并且具有与中空轴承的圆柱形内表面相邻并且至少部分地与中空轴承的圆柱形内表面接触的外表面。套筒可以在中空轴承内滑动，并且具有其中的套筒的中空轴承可围绕套筒轴线旋转并围绕轴承孔轴线倾斜。以这种方式，提供了对插入其中的轴提供旋转，平移和角运动的部件。可以包括密封以保护组合接头免受灰尘，污垢，碎屑等的影响。

3. 发明授权

US4020782A Convertible surfboard 失效
标题翻译：敞篷冲浪板
公开(公告)号：US4020782A
公开(公告)日：1977-05-03
申请号：US652536
申请日：1976-01-26
申请人： John Gleason
发明人： John Gleason
IPC分类号： B63B35/79 , A63C15/04
CPC分类号： B63B35/7943
摘要： A surfboard which is convertible from unpowered to motorized condition by the selective movement of a motor mounted in the elongated buoyant float member. Movement of the motor along the longitudinal axis of the float member does not substantially alter the floatation characteristics of the surfboard. Hand grip elements and a windshield are detachably connectable to the float member for use by the surfboard rider in a prone position during motorized operation.
摘要翻译：通过安装在细长浮力浮子构件中的马达的选择性运动，可以从无动力转换到电动状态的冲浪板。电动机沿着浮子部件的纵向轴线的运动基本上不会改变冲浪板的漂浮特性。手柄元件和挡风玻璃可拆卸地连接到浮动元件，以在电动操作期间由冲浪板骑手在俯卧位使用。

4. 发明授权

US09321317B2 Vehicle component 有权
标题翻译：车辆部件
公开(公告)号：US09321317B2
公开(公告)日：2016-04-26
申请号：US14110204
申请日：2012-03-13
申请人： John Gleason , Dirk Adamczyk
发明人： John Gleason , Dirk Adamczyk
IPC分类号： B60G7/00 , F16C7/02 , B60G17/019 , F16C7/06
CPC分类号： B60G7/001 , B60G17/019 , B60G2204/1162 , B60G2206/016 , B60G2206/10 , B60G2206/71 , B60G2206/72 , B60G2400/60 , B60G2400/64 , B60G2600/04 , F16C7/02 , F16C7/06 , F16C2202/00 , F16C2326/05
摘要： A vehicle component with at least two connection points, a structural component that extends between the connection points and rigidly connects them with one another. The structural component comprises at least one insert made of a ductile material and at least two connection zones that support or form the two connection points, at least one of the zones comprises plastic. The structural component comprises at least one intermediate section that connects the two connection zones rigidly to one another and comprises the insert or is formed by the insert, this section is more ductile than at least one of the two connection zones and, in relation to a mechanical overload of the structural component, forms a locally delimited weak-point or region.
摘要翻译：具有至少两个连接点的车辆部件，在连接点之间延伸并将它们彼此刚性连接的结构部件。结构部件包括至少一个由延性材料制成的插入件和至少两个支撑或形成两个连接点的连接区域，至少一个区域包括塑料。结构部件包括至少一个中间部分，其将两个连接区域彼此刚性连接并且包括插入件或由插入件形成，该部分比两个连接区域中的至少一个更具延性，并且相对于结构部件的机械过载形成局部限定的弱点或区域。

5. 发明申请

US20110237813A1 CO-PRECIPITATED SALTS OF FATTY ACIDS 有权
标题翻译：脂肪酸共同降低的盐
公开(公告)号：US20110237813A1
公开(公告)日：2011-09-29
申请号：US12731981
申请日：2010-03-25
申请人： John Gleason , Douglas Jost , Philip H. Merrell , Doug Caskey
发明人： John Gleason , Douglas Jost , Philip H. Merrell , Doug Caskey
IPC分类号： C11C3/00 , C07F3/06 , C07F3/04 , C07F15/02 , C07F1/08 , C07F3/02
CPC分类号： C07D233/64 , C07C51/412 , C07C53/02 , C07C53/10 , C07C53/122 , C07C53/126 , C07C55/08 , C07C55/10 , C07C55/12 , C07C55/14 , C07C55/16 , C07C57/03 , C07C57/10 , C07C57/12 , C07C57/145 , C07C57/15 , C07C59/08 , C07C59/105 , C07C59/19 , C07C59/245 , C07C59/265 , C07C63/06 , C07C63/16 , C07C65/10 , C07C229/06 , C07C229/24 , C07C229/26 , C07C279/14 , C07C323/58 , C07D307/62 , C07F9/091
摘要： A co-salt of a polyunsaturated fatty acid and a non-fatty acid is formed as a precipitate. The co-salt formed is free flowing and does not tend to agglomerate (cake) in storage. The resultant co-salt product will be easy to blend with other products to produce dietary supplements. These novel co-salt products may also tablet very well and may be added to current dietary supplement tablets.
摘要翻译：形成多不饱和脂肪酸和非脂肪酸的共盐作为沉淀物。形成的共盐是自由流动的，并且在储存中不趋于聚集（饼）。所得的共盐产品将容易与其他产品混合以产生膳食补充剂。这些新型共盐产品还可以非常好地加入片剂，并且可以加入到目前的膳食补充剂片剂中。

6. 发明申请

US20090189406A1 TAILGATE LIFT ASSISTOR 审中-公开
标题翻译： TAILGATE提升助理
公开(公告)号：US20090189406A1
公开(公告)日：2009-07-30
申请号：US12363124
申请日：2009-01-30
申请人： John Gleason
发明人： John Gleason
IPC分类号： B60P1/26 , B62D33/03
CPC分类号： B62D33/0273 , B60P1/26 , E05Y2201/20 , E05Y2201/21 , E05Y2201/234 , E05Y2201/256 , E05Y2201/266 , E05Y2201/458 , E05Y2900/00 , E05Y2900/516 , E05Y2900/544
摘要： A tailgate lift assistor that provides for a reduced force required to rotate or pivot a tailgate of a pickup truck or the like upwardly from a generally horizontal open position to a generally vertical closed position and in one embodiment the lift assistor is combined with a dampening mechanism that dampens the opening of the tailgate.
摘要翻译：一种后挡板提升装置，其提供将皮卡车等的后挡板从大致水平的打开位置向上旋转或枢转所需的减小的力，大致垂直的关闭位置，并且在一个实施例中，升降装置与阻尼机构这阻碍了后挡板的开口。

7. 发明授权

US4093231A Superfly game apparatus 失效
标题翻译：超级游戏机
公开(公告)号：US4093231A
公开(公告)日：1978-06-06
申请号：US821617
申请日：1977-08-03
申请人： John Gleason
发明人： John Gleason
IPC分类号： A63H27/04 , A63H33/00 , A63F9/00
CPC分类号： A63H33/00 , A63H27/04
摘要： Superfly game apparatus includes a simulated building structure having four side walls and a roof. A scaffold is carried by each side wall and a simulated helicopter is rotatably carried by the roof. A set of playing pieces is provided each of which is configured to represent a human figure and each of which is positionable at various elevational levels along a corner of the simulated building structure. Each of the corners of the simulated building structure are given retaining elements cooperable with the playing pieces for retaining such pieces. The game apparatus also includes elements which are manually operable to impart vertical movement to the playing pieces to move the pieces upwardly along the corners of the structure.
摘要翻译：超级游戏装置包括具有四个侧壁和屋顶的模拟建筑结构。脚手架由每个侧壁承载，模拟的直升机由屋顶可旋转地承载。提供了一组播放片，每个播放片被配置为表示人物，并且每个播放片可沿着模拟建筑结构的角落在不同的高度位置定位。模拟建筑结构的每个角落都具有与玩具相配合的保持元件，用于保持这些块。游戏装置还包括可手动操作的元件，以便使玩具的垂直运动沿着结构的角落向上移动。

8. 发明授权

US08178707B2 Co-precipitated salts of fatty acids 有权
标题翻译：共沉淀的脂肪酸盐
公开(公告)号：US08178707B2
公开(公告)日：2012-05-15
申请号：US12731981
申请日：2010-03-25
申请人： John Gleason , Douglas Jost , Philip H. Merrell , Doug Caskey
发明人： John Gleason , Douglas Jost , Philip H. Merrell , Doug Caskey
IPC分类号： C07C51/00 , C07F9/02
CPC分类号： C07D233/64 , C07C51/412 , C07C53/02 , C07C53/10 , C07C53/122 , C07C53/126 , C07C55/08 , C07C55/10 , C07C55/12 , C07C55/14 , C07C55/16 , C07C57/03 , C07C57/10 , C07C57/12 , C07C57/145 , C07C57/15 , C07C59/08 , C07C59/105 , C07C59/19 , C07C59/245 , C07C59/265 , C07C63/06 , C07C63/16 , C07C65/10 , C07C229/06 , C07C229/24 , C07C229/26 , C07C279/14 , C07C323/58 , C07D307/62 , C07F9/091
摘要： A co-salt of a polyunsaturated fatty acid and a non-fatty acid is formed as a precipitate. The co-salt formed is free flowing and does not tend to agglomerate (cake) in storage. The resultant co-salt product will be easy to blend with other products to produce dietary supplements. These novel co-salt products may also tablet very well and may be added to current dietary supplement tablets.
摘要翻译：形成多不饱和脂肪酸和非脂肪酸的共盐作为沉淀物。形成的共盐是自由流动的，并且在储存中不趋于聚集（饼）。所得的共盐产品将容易与其他产品混合以产生膳食补充剂。这些新型共盐产品还可以非常好地加入片剂，并且可以加入到目前的膳食补充剂片剂中。

9. 发明授权

US07574841B2 Method of erecting a wall having a vertically adjustable hinged support column 有权
标题翻译：竖立具有垂直调节铰链支柱的墙壁的方法
公开(公告)号：US07574841B2
公开(公告)日：2009-08-18
申请号：US11861898
申请日：2007-09-26
申请人： Wayne A. Knepp , Tim Wetterhus , Don Ferguson , Dave Fehr , Paul Remmele , John Gleason
发明人： Wayne A. Knepp , Tim Wetterhus , Don Ferguson , Dave Fehr , Paul Remmele , John Gleason
IPC分类号： E04B1/20
CPC分类号： E02D29/0275 , E02D27/42 , E04B1/215 , E04B2001/2616 , E04B2001/268 , E04C3/122 , E04C3/34 , E04C3/36
摘要： A height adjustable jack piling assembly has a piling with a top and a bottom. A hinge axis is disposed on the top and a bearing plate is disposed at the bottom. A height adjustment mechanism extends upwardly from the bearing plate and through the piling to raise the piling, and the corresponding hinge axis, by operating the height adjustment mechanism from the top. The method includes placing a jack piling assembly and second lower piling, each having a hinge axis, into the earth and operating the height adjustment mechanism of the jack piling assembly to align the hinge axes.
摘要翻译：高度可调的千斤顶打桩组件具有顶部和底部的打桩。铰链轴设置在顶部并且在底部设置有支承板。高度调节机构通过从顶部操作高度调节机构，从支承板向上延伸并通过打桩抬起打桩和相应的铰链轴线。该方法包括将千斤顶打桩组件和每个具有铰链轴线的第二下部打桩件放置到地面中并操作千斤顶打桩组件的高度调节机构以对齐铰链轴线。

10. 发明申请

US20070295846A1 Wire spool caddy 失效
标题翻译：线芯筒
公开(公告)号：US20070295846A1
公开(公告)日：2007-12-27
申请号：US11715816
申请日：2007-03-07
申请人： John Gleason
发明人： John Gleason
IPC分类号： B65H49/18
CPC分类号： B65H49/32
摘要： A caddy for carrying spools such as those for electrical wire. The caddy has complementary T-shaped slots in opposite side walls and members affixed between the side wall that support the spools, forming a cage, and one member rides within the T-shaped slot. The moving member may be pulled away from the cage to allow for room to release a spool from its cage, but the member will move by itself in response to movement of the caddy to keep the spool or spools locked within the cage.
摘要翻译：用于承载诸如电线的卷轴的球童。球笼在相对侧壁上具有互补的T形槽，并且固定在支撑卷轴的侧壁之间的构件，形成保持架，并且一个构件骑在T形槽内。移动构件可以从保持架拉出以允许从其保持架释放线轴的空间，但是构件将响应于球笼的移动而自身移动以保持线轴或线轴锁定在保持架内。

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