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1. 发明授权

US4406153A Ultrasonic beam characterization device 失效
标题翻译：超声波束表征装置
公开(公告)号：US4406153A
公开(公告)日：1983-09-27
申请号：US296856
申请日：1981-08-27
申请人： Jonathan Ophir , Nabil F. Maklad , Paul M. Jaeger
发明人： Jonathan Ophir , Nabil F. Maklad , Paul M. Jaeger
IPC分类号： G01H3/00 , G01S7/52 , G01N37/00
CPC分类号： G01S7/52052 , G01H3/005
摘要： An ultrasound beam charcterization device is provided which may be employed during manufacture of diagnostic ultrasound equipment or during use thereof in the field in order to determine the beam profile of the ultrasonic transducer. The device includes a substantially air tight enclosure or box, having therein a thin element characterized by the properties of substantially uniform acoustic scattering and a different back scatter coefficient than the surrounding filler medium. The element is preferably oriented along or parallel to the axis of radiation of the transducer, and is advantageously in the form of a synthetic resin cellular foam material having a relatively high scattering level, which may be embedded in a different foam of lower scattering level. A reticulated cellular foam and salt solution fill the remaining volume of the preferred device, thereby permitting the imaging of transducer beam profiles in a tissue equivalent material.
摘要翻译：提供超声波束形成装置，其可以在诊断超声设备的制造期间或其在现场的使用期间使用，以便确定超声换能器的束轮廓。该装置包括基本上气密的外壳或盒，其中具有薄的元件，其特征在于具有基本上均匀的声散射和与周围填料介质不同的背散射系数的特性。该元件优选地沿着换能器的辐射轴线或平行的方向定向，并且有利地是具有相对高的散射水平的合成树脂泡沫材料的形式，其可以嵌入在较低散射水平的不同泡沫中。网状细胞泡沫和盐溶液填充优选装置的剩余体积，从而允许在组织等效材料中成像换能器束轮廓。

2. 发明授权

US4286455A Ultrasound phantom 失效
标题翻译：超声幻影
公开(公告)号：US4286455A
公开(公告)日：1981-09-01
申请号：US36016
申请日：1979-05-04
申请人： Jonathan Ophir , Nabil F. Maklad , Paul M. Jaeger
发明人： Jonathan Ophir , Nabil F. Maklad , Paul M. Jaeger
IPC分类号： G01H3/00 , G01S7/52 , G01N37/00
CPC分类号： G01S7/52052 , G01H3/005
摘要： An ultrasound phantom is provided which has ultrasound wave velocities, attenuation coefficients and scattering coefficients which closely mimic those of human tissue and which permits diagnostic ultrasound equipment to be accurately tested and calibrated on a continuing day-to-day basis. The phantom preferably includes a substantially air-tight enclosure or box, having therein a quantity of reticulated synthetic resin foam material and a salt water solution. The ultrasonic characteristics of the phantom are completely uniform, stable and reproduceable, can be varied at will by using different foam materials and/or liquids, and the phantom can be stored and used at room temperature without degradation thereof. Localized zones having different ultrasonic qualities for mimicking various normal and pathological tissues can also be provided by hollowed, cut-out regions within the foam material, with different inserts located within certain of the hollowed regions.
摘要翻译：提供超声体模，其超声波速度，衰减系数和散射系数与人体组织的超声波速度，散射系数密切相关，并允许诊断超声设备在持续的日常基础上进行准确的测试和校准。该体模优选地包括基本上气密的外壳或盒，其中具有一定数量的网状合成树脂泡沫材料和盐水溶液。体模的超声波特征是完全均匀，稳定和可重现的，可以通过使用不同的泡沫材料和/或液体随意变化，并且可以在室温下储存和使用体模而不降解其。具有用于模拟各种正常和病理组织的具有不同超声波质量的局部区域也可以由泡沫材料内的中空的切出区域提供，其中位于某些中空区域内的不同的插入物。

3. 发明授权

US4389893A Precision ultrasound attenuation measurement 失效
标题翻译：精密超声衰减测量
公开(公告)号：US4389893A
公开(公告)日：1983-06-28
申请号：US268882
申请日：1981-06-01
申请人： Jonathan Ophir , Nabil F. Maklad
发明人： Jonathan Ophir , Nabil F. Maklad
IPC分类号： A61B8/00 , A61B8/08 , G01H15/00 , G01N29/00 , G01N29/04 , G01N29/11 , G01N29/28 , G01S7/52 , G10K11/35
CPC分类号： G10K11/352 , A61B8/08 , G01N29/0645 , G01N29/11 , G01N29/343 , G01S7/52036 , G01N2291/0289
摘要： Method and apparatus for measuring an attenuation characteristic in a region of interest using ultrasound wherein two statistically independent set of values are accumulated as a difference between logarithms of pairs of each signal set, and the attenuation characteristic calculated as a central tendency parameter of each set of values.
摘要翻译：用于使用超声波测量感兴趣区域中的衰减特性的方法和装置，其中两个统计上独立的值集合作为每个信号组的对的对数之间的差异，以及作为每组信号集合的中心趋势参数计算的衰减特性价值观。

4. 发明授权

US5107837A Method and apparatus for measurement and imaging of tissue compressibility or compliance 失效
标题翻译：用于测量和成像组织可压性或符合性的方法和装置
公开(公告)号：US5107837A
公开(公告)日：1992-04-28
申请号：US535312
申请日：1990-06-08
申请人： Jonathan Ophir , Youseph Yazdi
发明人： Jonathan Ophir , Youseph Yazdi
IPC分类号： A61B8/08 , A61B5/103 , G01N3/00 , G01N29/00 , G01N29/07 , G01N29/22 , G01N29/30 , G01N29/38 , G01N29/50 , G01S15/89
CPC分类号： G01S15/8945 , A61B5/0051 , A61B5/441 , G01N29/07 , G01N29/223 , G01N29/30 , G01N29/38 , G01N29/50 , G01S7/52042 , A61B8/4272 , G01N2203/0089 , G01N2291/02827 , G01N2291/101
摘要： An improved ultrasonic pulse-echo method and apparatus that has particular application in making precision measurements of compressibility in any backscattering material, in particular organic tissue, is disclosed. The method employs a standard transducer or transducer containing device which is translated transaxially, thereby compressing or displacing a proximal region of a target body in small known increments. At each increment, a pulse is emitted and an echo sequence (A-line) is detected from regions within the target along the sonic travel path or beam of the transducer. Resulting time shifts in echo segments corresponding to features in the target provide relative and quantitative information concerning compressibility of the target.
摘要翻译：公开了一种改进的超声脉冲回波方法和装置，其特别适用于在任何后向散射材料，特别是有机组织中精确测量可压缩性。该方法采用标准的换能器或换能器容纳装置，该装置被外延地平移，从而以小的已知增量压缩或移位靶体的近端区域。在每个增量处，发射脉冲，并且沿着声波传播路径或传感器的波束从目标内的区域检测回波序列（A线）。对应于目标中的特征的回波段中的所得时间偏移提供了关于目标的可压缩性的相对和定量信息。

5. 发明授权

US4669482A Pulse echo method and apparatus for sound velocity estimation in vivo 失效
标题翻译：用于体内声速估计的脉冲回波方法和装置
公开(公告)号：US4669482A
公开(公告)日：1987-06-02
申请号：US791719
申请日：1985-10-28
申请人： Jonathan Ophir
发明人： Jonathan Ophir
IPC分类号： A61B8/00 , A61B8/08 , G01H5/00 , G01S7/52 , G01S15/89 , A61B10/00
CPC分类号： G01S7/52025 , A61B8/00 , G01H5/00 , G01S15/8913
摘要： Sound velocity along a straight segment is estimated by measuring ultrasound pulse travel time as ultrasound pulses are directed along the straight segment from successively different transmitting or receiving positions. A sequence of data pairs comprising travel times and distances traveled is measured and plotted on a graph. Estimated sound velocity is derived from the slope of affine equation fitted to the plotted points.
摘要翻译：通过测量超声波脉冲行进时间，通过连续不同的发射或接收位置沿着直线引导超声波脉冲，来估计沿直线段的声速。测量包括旅行时间和旅行距离的数据对序列并绘制在图上。估计的声速从拟合到绘制点的仿射方程的斜率得出。

6. 发明申请

US20100010353A1 Methods For Determining Displacement Or Strain Of A Target Body 失效
标题翻译：确定靶体位移或应变的方法
公开(公告)号：US20100010353A1
公开(公告)日：2010-01-14
申请号：US12501419
申请日：2009-07-11
申请人： Raffaella Righetti , Jonathan Ophir
发明人： Raffaella Righetti , Jonathan Ophir
IPC分类号： A61B8/00 , G06F19/00
CPC分类号： A61B8/08 , A61B5/442 , A61B8/485 , A61B8/488
摘要： The invention is directed toward a new method for estimating and imaging the spatial and temporal mechanical behavior of materials in responses to a mechanical stimulus. This method is designed to work in inherently noisy applications, such as the imaging of the time-dependent mechanical behavior of biological tissues in vivo and using a preferred hand-held configuration of scanning.
摘要翻译：本发明涉及用于在对机械刺激的响应中估计和成像材料的空间和时间机械行为的新方法。该方法被设计为在固有的噪声应用中工作，例如在体内成像生物组织的时间依赖性机械行为并使用优选的手持扫描配置。

7. 发明授权

US4993416A System for ultrasonic pan focal imaging and axial beam translation 失效
标题翻译：超声波焦点成像和轴向光束平移系统
公开(公告)号：US4993416A
公开(公告)日：1991-02-19
申请号：US343405
申请日：1989-04-25
申请人： Jonathan Ophir
发明人： Jonathan Ophir
IPC分类号： G01S15/89 , G10K11/35
CPC分类号： G10K11/352 , G01S15/8934
摘要： The present invention provides a novel method and apparatus which allows concomitant imaging and rapid axial beam translation measurements used to calculate the attenuation characteristics of a target body. The present invention employs an ultrasonic scanner which contains a plurality of matched transducer elements. These elements are staggered on a mechanism which sequentially places each transducer opposite an acoustic window at axially spaced positions along a common axis. The present invention also enables axial beam translation techniques to be adapted to current ultrasonic imaging systems.
摘要翻译：本发明提供了一种新颖的方法和装置，其允许用于计算目标体的衰减特性的伴随成像和快速轴向束平移测量。本发明采用包含多个匹配的换能器元件的超声波扫描器。这些元件在一个机构上交错，该机构沿着公共轴沿轴向间隔开的位置将每个换能器相对地放置在声窗上。本发明还使得轴向束平移技术能够适应于当前的超声成像系统。

8. 发明授权

US4878500A Multi-beam tracking for angle error correction in speed of sound estimations 失效
标题翻译：用于角度误差校正的多光束跟踪在声音估计速度
公开(公告)号：US4878500A
公开(公告)日：1989-11-07
申请号：US218810
申请日：1988-07-13
申请人： Jonathan Ophir , David P. Shattuck
发明人： Jonathan Ophir , David P. Shattuck
IPC分类号： A61B8/00 , G01H5/00 , G01S7/52 , G01S15/89
CPC分类号： A61B8/00 , G01H5/00 , G01S15/8913 , G01S7/52025
摘要： This invention relates to a method for correcting angle error present in in vivo sound velocity estimations. More particularly, this invention relates to a method for estimating the angle of misdirection of a tracked ultrasound beam used in sound velocity measurements in conjunction with multi-tracking ultrasound beams.
摘要翻译：本发明涉及用于校正体内声速估计中存在的角度误差的方法。更具体地，本发明涉及一种用于估计用于声速测量中的跟踪的超声波束与多跟踪超声波束的偏转方向的方法。

9. 发明授权

US4807635A Pulse centroid echo method and apparatus for enhanced sound velocity estimation in vivo 失效
标题翻译：脉冲质心回波法和体内增强声速估计装置
公开(公告)号：US4807635A
公开(公告)日：1989-02-28
申请号：US887349
申请日：1986-07-21
申请人： Jonathan Ophir
发明人： Jonathan Ophir
IPC分类号： A61B8/00 , G01H5/00 , G01S7/52 , G01S15/89 , A61B10/00
CPC分类号： A61B8/00 , G01H5/00 , G01S15/8913 , G01S7/52025
摘要： A method and apparatus of enhancing the accuracy of in vivo sound velocity estimation by identifying segments of different sound velocity along a tracked ultrasound beam. The effects of refraction on the tracked beam at the interface between tissue regions are estimated. Also disclosed is a technique for estimating the refractive effects of naturally occurring and artificially introduced acoustical contrast fluids. The accuracy of the sound velocity measurements is increased by utilizing the centroid-to-centroid distance between the pulses produced by ultrasound sending and receiving transducers in calculating the ultrasound beam velocity.
摘要翻译：一种通过沿跟踪的超声波束识别不同声速的片段来提高体内声速估计精度的方法和装置。估计在组织区域之间的界面处的折射对跟踪光束的影响。还公开了一种用于估计天然存在和人为引入的声学对比流体的折射效应的技术。通过在计算超声波束速度时利用由超声发送和接收换能器产生的脉冲之间的质心到质心距离来增加声速测量的精度。

10. 发明授权

US4777958A Method for enhancing the accuracy of in vivo sound velocity estimation 失效
标题翻译：提高体内声速估计精度的方法
公开(公告)号：US4777958A
公开(公告)日：1988-10-18
申请号：US823332
申请日：1986-01-28
申请人： Jonathan Ophir
发明人： Jonathan Ophir
IPC分类号： A61B8/00 , G01H5/00 , G01S7/52 , G01S15/89 , A61B10/00
CPC分类号： A61B8/00 , G01H5/00 , G01S15/8913 , G01S7/52025
摘要： A method of enhancing the accuracy of in vivo sound velocity estimation by identifying segments of different sound velocity along a tracked ultrasound beam. The effects of refraction on the tracked beam at the interface between tissue regions are estimated. Also disclosed is a technique for estimating the refractive effects of naturally occurring and artificially introduced acoustical contrast fluids.
摘要翻译：通过沿着跟踪的超声波束识别不同声速的段来提高体内声速估计精度的方法。估计在组织区域之间的界面处的折射对跟踪光束的影响。还公开了一种用于估计天然存在和人为引入的声学对比流体的折射效应的技术。

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