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1. 发明授权

US6066776A Self-forming prosthesis for repair of soft tissue defects 失效
标题翻译：用于修复软组织缺损的自体成形假体
公开(公告)号：US6066776A
公开(公告)日：2000-05-23
申请号：US895050
申请日：1997-07-16
申请人： Jonathan L. Goodwin , Peter H. Gingras , Steve A. Herweck
发明人： Jonathan L. Goodwin , Peter H. Gingras , Steve A. Herweck
IPC分类号： A61F2/00 , A61F2/02
CPC分类号： A61F2/0063 , Y10S623/901
摘要： A prosthesis is provided that is advantageously used to fill a soft tissue or muscle defect, such as an inquinal or femoral hernia. In a first aspect of the invention, multiple layers of a flexible, mesh material are attach together at a finite number of joins. A tab is placed at the geometric center of one of the mesh layers to facilitate insertion of the mesh into the defect. The tab also creates a blunt tip that reduces irritation and discomfort to the patient. In a second aspect of the invention, a prosthesis is provided that includes a barrier layer between two or more layers of flexible, mesh material to prevent adhesion of the device to the tissue. All layers are attached together by a finite number of joins. A tab is placed at the geometric center of one of the mesh layers to facilitate insertion of the mesh into the defect. The prostheses of the invention are self-forming in that they change from a two dimensional configuration to a three dimensional configuration upon insertion of the device into the defect.
摘要翻译：提供了一种假体，其有利地用于填充软组织或肌肉缺损，例如询问或股骨疝。在本发明的第一方面中，柔性网状材料的多层以有限数量的连接连接在一起。在一个网格层的几何中心处放置一个突片，以便于将网格插入到缺陷中。该标签还创建一个钝头，减少患者的刺激和不适。在本发明的第二方面中，提供一种假体，其包括两层或多层柔性网状材料之间的阻挡层，以防止该装置粘附到组织上。所有层通过有限数量的连接连接在一起。在一个网格层的几何中心处放置一个突片，以便于将网格插入到缺陷中。本发明的假体是自形成的，因为它们在将装置插入缺陷时从二维构型变为三维构型。

2. 发明授权

US06808533B1 Covered stent and method of covering a stent 有权
标题翻译：覆盖支架和覆盖支架的方法
公开(公告)号：US06808533B1
公开(公告)日：2004-10-26
申请号：US09627566
申请日：2000-07-28
申请人： Jonathan L. Goodwin , Gary A. Jordan , Peter H. Gingras
发明人： Jonathan L. Goodwin , Gary A. Jordan , Peter H. Gingras
IPC分类号： A61F206
CPC分类号： A61F2/86 , A61F2/91 , A61F2002/072 , A61F2210/0076 , A61F2220/005 , A61L31/10 , A61L31/146 , C08L27/18
摘要： A radially deployable covered stent that predictably and dependably expands to an increased diameter state at relatively low deployment pressures while concomitantly minimizing the risk of tearing of the stent covering during expansion. The stent covering includes an inner cover and an outer cover that are bonded together through and around the stent structure to cover the stent. The stent cover is constructed from expanded polytetrafluoroethylene (ePTFE) having a structure of nodes interconnected by fibrils. The stent covering has a radial thickness of at least about 0.008″ and an average internodal distance (IND) of at least about 100 microns when the stent is in the reduced diameter, unexpanded state. The covered stent deploys at an average deployment pressure of less than or equal to about 10 atm. A method for covering a stent structure according to the present invention includes placing a compression member in the form of a tubular sleeve over the outer cover and heating the compressed covered stent to bond the inner cover to the outer cover. An adhesive in the form of an aqueous dispersion of PTFE can be applied to either the inner cover or the outer cover to facilitate bonding of the inner cover to the outer cover.
摘要翻译：可径向展开的覆盖支架可预测地且可靠地在相对较低的部署压力下扩张到增加的直径状态，同时最小化扩张期间支架覆盖物撕裂的风险。支架覆盖物包括通过支架结构并且围绕支架结构粘合在一起以覆盖支架的内盖和外盖。支架盖由膨胀的聚四氟乙烯（ePTFE）构成，其具有通过纤维互连的节点结构。当支架处于减小直径，未膨胀状态时，支架覆盖物具有至少约0.008“的径向厚度和至少约100微米的平均间隔距离（IND）。覆盖的支架以小于或等于约10atm的平均部署压力部署。根据本发明的覆盖支架结构的方法包括将管状套筒形式的压缩构件放置在外盖上并加热压缩的被覆盖的支架以将内盖结合到外盖。可以将PTFE的水性分散体形式的粘合剂施加到内盖或外盖上，以便于内盖与外盖接合。

3. 发明授权

US08740930B2 Embolic filter device independent of treatment device 有权
标题翻译：栓塞过滤装置独立于治疗装置
公开(公告)号：US08740930B2
公开(公告)日：2014-06-03
申请号：US12392141
申请日：2009-02-25
申请人： Jonathan L. Goodwin
发明人： Jonathan L. Goodwin
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0065 , A61F2230/0071
摘要： A self-expanding filter for collecting emboli or thrombi in a vessel of a patient is disclosed. The filter has a tubular filter body that coils or spirals around an outer surface of an adjacently located, independent treatment device in a corkscrew fashion when deployed from a sheath delivery catheter. When fully deployed, an outer surface of the coiled tubular body conforms to the inner wall of the vessel and an inner surface of the coiled tubular body conforms to an outer surface of the treatment device. The treatment device is disposed within a longitudinal opening extending through the expanded, coiled tubular body of the filter during an interventional procedure.
摘要翻译：公开了一种用于收集患者血管中栓塞或血栓的自扩张过滤器。过滤器具有管状过滤器主体，其在从护套输送导管展开时以螺塞式方式围绕相邻位置的独立治疗装置的外表面进行卷绕或螺旋。当完全展开时，螺旋管状体的外表面符合容器的内壁，并且螺旋管状体的内表面符合治疗装置的外表面。治疗装置设置在纵向开口中，该纵向开口在介入手术期间延伸穿过过滤器的膨胀的，盘绕的管状体。

4. 发明申请

US20100217303A1 EMBOLIC FILTER DEVICE INDEPENDENT OF TREATMENT DEVICE 有权
标题翻译：独立的治疗装置的嵌体过滤装置
公开(公告)号：US20100217303A1
公开(公告)日：2010-08-26
申请号：US12392141
申请日：2009-02-25
申请人： Jonathan L. Goodwin
发明人： Jonathan L. Goodwin
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0065 , A61F2230/0071
摘要： A self-expanding filter for collecting emboli or thrombi in a vessel of a patient is disclosed. The filter has a tubular filter body that coils or spirals around an outer surface of an adjacently located, independent treatment device in a corkscrew fashion when deployed from a sheath delivery catheter. When fully deployed, an outer surface of the coiled tubular body conforms to the inner wall of the vessel and an inner surface of the coiled tubular body conforms to an outer surface of the treatment device. The treatment device is disposed within a longitudinal opening extending through the expanded, coiled tubular body of the filter during an interventional procedure.
摘要翻译：公开了一种用于收集患者血管中栓塞或血栓的自扩张过滤器。过滤器具有管状过滤器主体，其在从护套输送导管展开时以螺塞式方式围绕相邻位置的独立治疗装置的外表面进行卷绕或螺旋。当完全展开时，螺旋管状体的外表面符合容器的内壁，并且螺旋管状体的内表面符合治疗装置的外表面。治疗装置设置在纵向开口中，该纵向开口在介入手术期间延伸穿过过滤器的膨胀的，盘绕的管状体。

5. 发明授权

US07354449B2 Covered stent and method of covering a stent 有权
标题翻译：覆盖支架和覆盖支架的方法
公开(公告)号：US07354449B2
公开(公告)日：2008-04-08
申请号：US10972197
申请日：2004-10-22
申请人： Jonathan L. Goodwin , Gary A. Jordan , Peter Gingras
发明人： Jonathan L. Goodwin , Gary A. Jordan , Peter Gingras
IPC分类号： A61F2/06
CPC分类号： A61F2/86 , A61F2/91 , A61F2002/072 , A61F2210/0076 , A61F2220/005 , A61L31/10 , A61L31/146 , C08L27/18
摘要： A radially deployable covered stent that predictably and dependably expands to an increased diameter state at relatively low deployment pressures while concomitantly minimizing the risk of tearing of the stent covering during expansion. The stent covering includes an inner cover and an outer cover that are bonded together through and around the stent structure to cover the stent. The stent cover is constructed from expanded polytetrafluoroethylene (ePTFE) having a structure of nodes interconnected by fibrils. The stent covering has a radial thickness of at least about 0.008″ and an average internodal distance (IND) of at least about 100 microns when the stent is in the reduced diameter, unexpanded state. The covered stent deploys at an average deployment pressure of less than or equal to about 10 atm. A method for covering a stent structure according to the present invention includes placing a compression member in the form of a tubular sleeve over the outer cover and heating the compressed covered stent to bond the inner cover to the outer cover. An adhesive in the form of an aqueous dispersion of PTFE can be applied to either the inner cover or the outer cover to facilitate bonding of the inner cover to the outer cover.
摘要翻译：可径向展开的覆盖支架可预测地且可靠地在相对较低的部署压力下扩张到增加的直径状态，同时最小化扩张期间支架覆盖物撕裂的风险。支架覆盖物包括通过支架结构并且围绕支架结构粘合在一起以覆盖支架的内盖和外盖。支架盖由膨胀的聚四氟乙烯（ePTFE）构成，其具有通过纤维互连的节点结构。当支架处于减小直径，未膨胀状态时，支架覆盖物具有至少约0.008“的径向厚度和至少约100微米的平均间隔距离（IND）。覆盖的支架以小于或等于约10atm的平均部署压力部署。根据本发明的覆盖支架结构的方法包括将管状套筒形式的压缩构件放置在外盖上并加热压缩的被覆盖的支架以将内盖结合到外盖。可以将PTFE的水性分散体形式的粘合剂施加到内盖或外盖上，以便于内盖与外盖接合。

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