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1. 发明授权

US5576170A Photographic element and method of making a silver halide emulsion 失效
标题翻译：摄影元件及卤化银乳剂的制造方法
公开(公告)号：US5576170A
公开(公告)日：1996-11-19
申请号：US430954
申请日：1995-04-28
申请人： Jon N. Eikenberry , Robert E. Bernard
发明人： Jon N. Eikenberry , Robert E. Bernard
IPC分类号： G03C1/005 , G03C1/10 , G03C1/34 , G03C1/08 , G03C1/09
CPC分类号： G03C1/346 , G03C1/10 , G03C1/0051
摘要： A photographic element comprising a support having situated thereon a silver halide emulsion, the emulsion comprising an alkynylamine compound of the formula: wherein Z represents atoms necessary to complete a 5 to 10-membered heterocyclic ring system, R.sup.1 represents hydrogen or an alkyl of from 1 to 5 carbon atoms, and R.sup.2 represents hydrogen, or an alkyl, aryl, heteroaryl, carbocyclic or heterocyclic group; andat least one dihydroxy aryl compound represented by formula II or III: ##STR1## wherein R.sup.3 to R.sup.12 are independently selected from the group consisting of hydrogen, hydroxy, sulfonate, or an alkyl of from 1 to 5 carbon atoms, and wherein at least two of such groups represent a hydroxy group.
摘要翻译：一种照相元件，包括其上设置有卤化银乳剂的载体，所述乳液包含下式的炔基胺化合物：其中Z表示完成5至10元杂环系统所必需的原子，R 1表示氢或1至5个碳原子的烷基，R 2表示氢，或烷基，芳基，杂芳基，碳环或杂环基; 和由式II或III表示的至少一种二羟基芳基化合物：其中R 3至R 12独立地选自氢，羟基，磺酸酯或1位的烷基至5个碳原子，并且其中这些基团中的至少两个表示羟基。

2. 发明授权

US5968724A Silver halide photographic elements with reduced fog 有权
标题翻译：卤化银照相元件减少雾
公开(公告)号：US5968724A
公开(公告)日：1999-10-19
申请号：US177154
申请日：1998-10-22
申请人： Jon N. Eikenberry , Roger L. Klaus , Roger L. Lok , Jerzy Z. Mydlarz , Brian S. White
发明人： Jon N. Eikenberry , Roger L. Klaus , Roger L. Lok , Jerzy Z. Mydlarz , Brian S. White
IPC分类号： G03C1/005 , G03C1/015 , G03C1/34 , G03C1/08
CPC分类号： G03C1/34 , G03C1/0051
摘要： This invention relates to silver halide photographic element comprising a silver halide emulsion chemically sensitized in the presence of an isothiazolin-one compound represented by the formula ##STR1## wherein R.sup.1 is a substituent; and Z is a substituted or unsubstituted saturated ring, wherein the isothiazolin-one compound was added after precipitation of the emulsion.
摘要翻译：本发明涉及卤化银照相元件，该卤化银照相元件包含在下式表示的异噻唑啉一化合物存在下化学增感的卤化银乳剂，其中R1是取代基; Z是取代或未取代的饱和环，其中在沉淀出乳液后加入异噻唑啉一化合物。

3. 发明授权

US5155024A Binder composition and analytical element having stabilized peroxidase in layer containing the composition 失效
标题翻译：包含组合物的层中的稳定的过氧化物的粘合剂组合物和分析元件
公开(公告)号：US5155024A
公开(公告)日：1992-10-13
申请号：US884249
申请日：1986-07-10
申请人： Jon N. Eikenberry
发明人： Jon N. Eikenberry
IPC分类号： C12Q1/28 , G01N33/543
CPC分类号： G01N33/54386 , C12Q1/28 , Y10S435/805 , Y10S435/81 , Y10S436/81
摘要： An analytical element has a peroxidase-labeled ligand analog distributed within a water-soluble binder composition comprising at least about 50 percent, by weight, of poly(vinyl alcohol). As a result, the peroxidase retains more of its stability prior to use. Such elements can be used to determine any of a number of immunologically reactive analytes, such as digoxin.

4. 发明授权

US06593073B1 Core/shell emulsions with enhanced photographic response 失效
标题翻译：具有增强的摄影反应的核/壳乳液
公开(公告)号：US06593073B1
公开(公告)日：2003-07-15
申请号：US09467613
申请日：1999-12-20
申请人： Jon N. Eikenberry , Yun C. Chang
发明人： Jon N. Eikenberry , Yun C. Chang
IPC分类号： G03C1005
CPC分类号： G03C1/10 , G03C1/035 , G03C1/12 , G03C7/3022 , G03C2001/03535 , G03C2001/03558 , G03C2200/24
摘要： A silver halide photographic element comprises at least one silver halide emulsion layer comprising a silver halide emulsion comprising core/shell silver halide grains wherein the core region comprises silver bromide with from about 5 to about 20% silver iodide and the shell region comprises silver bromide with about 0.1 to about 10% silver iodide and said layer contains a fragmentable electron donor compound of the formula X—Y′ or a compound which contains a moiety of the formula —X—Y′; wherein X is an electron donor moiety, Y′ is a leaving proton H or a leaving group Y, with the proviso that if Y′ is a proton, a base, &bgr;−, is covalently linked directly or indirectly to X, and wherein: 1) X—Y′ has an oxidation potential between 0 and about 1.4 V; and 2) the oxidized form of X—Y′ undergoes a bond cleavage reaction to give the radical X• and the leaving fragment Y′; and, optionally, 3) the radical X• has an oxidation potential≦−0.7V.
摘要翻译：卤化银照相元件包括至少一种卤化银乳剂层，其包含卤化银乳剂，其包含核/壳卤化银颗粒，其中芯区域包含溴化银和约5至约20％的碘化银，并且壳区域包含溴化银，约0.1至约10％的碘化银，并且所述层含有式XY'的可裂解电子给体化合物或含有式-X-Y'部分的化合物;其中X为电子给体部分，Y'为离去质子H或离去基团Y，条件是如果Y'是质子，则碱，β - 与X直接或间接共价连接，并且其中：1）XY'具有介于0和约1.4之间的氧化电位 V; 和2）X-Y'的氧化形式经历键断裂反应，得到基团X和离去片段Y';和任选地3）基团X的氧化势<= -0.7V。

5. 发明授权

US4547460A Multizone analytical element and method for analyte determination 失效
标题翻译：多分析元素和分析物测定方法
公开(公告)号：US4547460A
公开(公告)日：1985-10-15
申请号：US600641
申请日：1984-04-16
申请人： Jon N. Eikenberry
发明人： Jon N. Eikenberry
IPC分类号： G01N33/48 , C12Q1/48 , G01N21/78 , G01N31/22 , G01N33/52 , G01N33/72 , C12Q1/32
CPC分类号： C12Q1/48 , G01N33/525 , Y10S435/805 , Y10T436/25125
摘要： A multizone analytical element for the determination of an analyte in an aqueous liquid comprises a registration zone and a porous spreading zone to receive and transport the aqueous liquid. The spreading zone contains a nonpolymeric quaternary ammonium compound represented by either of the structures: ##STR1## wherein represents a single or double bond; R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are independently alkyl; aryl; cycloalkyl; or alkaryl; provided that R.sub.1, R.sub.2, R.sub.3 and R.sub.4 together comprise at least 12 carbon atoms; or R.sub.1 and R.sub.2 taken together with the nitrogen atom, form a quaternary 5- to 16-membered heterocyclic ring; or R.sub.1, R.sub.2 and R.sub.3 taken together with the nitrogen atom, form a quaternary 5- to 16-membered heterocyclic ring; and X.sup.- is a monovalent anion. This element is particularly useful for rate determinations of enzymes, such as alanine aminotransferase and aspartate aminotransferase, in liquids containing bilirubin or protein which may interfere with the accuracy of the assay.
摘要翻译：用于测定水性液体中的分析物的多区分析元件包括配准区和多孔扩散区以接收和输送含水液体。铺展区含有由以下结构之一表示的非聚合季铵化合物：图1a。 Ib。

6. 发明授权

US4333733A Continuous release of reagent in an analytical element to reduce assay interference 失效
标题翻译：在分析元件中连续释放试剂以减少测定干扰
公开(公告)号：US4333733A
公开(公告)日：1982-06-08
申请号：US169704
申请日：1980-07-17
申请人： Karl J. Sanford , Jon N. Eikenberry
发明人： Karl J. Sanford , Jon N. Eikenberry
IPC分类号： G01N21/78 , G01N33/52 , G01N33/68 , G01N33/84 , G01N31/22
CPC分类号： G01N33/84 , G01N33/525 , G01N33/68 , Y10T436/25125
摘要： Analytical elements and methods for the selective determination of an analyte in aqueous fluids containing the analyte. These elements and methods feature means for continuously releasing chromogenic indicator reagent from a reagent zone to a reaction zone. The continuous release means is responsive to the application of a sample of the fluid to continuously release reagent into the reaction zone at a rate producing color response corresponding to interaction of the indicator with the analyte and reduced interaction of the indicator with interferents. In preferred embodiments, albumin is determined in the presence of interfering proteins such as globulins using buffered chromogenic indicator reagent. In such embodiments, when protein interferents are present, their interference can be substantially eliminated for up to three minutes, during which time color response is substantially only from the interaction of albumin and reagent. The determination of albumin follows from such color response.
摘要翻译：用于选择性测定含有分析物的含水流体中的分析物的分析元素和方法。这些元件和方法具有用于将显色剂指示剂从试剂区域连续释放到反应区域的装置。连续释放装置响应于流体样品的应用，以以指示剂与分析物的相互作用产生颜色响应的速率将试剂连续释放到反应区中，并减少指示剂与干扰物的相互作用。在优选的实施方案中，使用缓冲的显色剂指示剂在干扰蛋白例如球蛋白的存在下测定白蛋白。在这样的实施方案中，当存在蛋白质干扰物时，其干扰可以基本上消除长达三分钟，在此期间，颜色响应基本上仅来自白蛋白和试剂的相互作用。白蛋白的测定遵循这种颜色反应。

7. 发明授权

US06506548B1 Silver halide photographic materials containing solubilized antifoggants 失效
标题翻译：含有溶解的防灰雾剂的卤化银照相材料
公开(公告)号：US06506548B1
公开(公告)日：2003-01-14
申请号：US10014990
申请日：2001-12-11
申请人： Roger L. Klaus , George J. Burgmaier , Jon N. Eikenberry , Jerzy Z. Mydlarz , Nicholas E. Grzeskowiak
发明人： Roger L. Klaus , George J. Burgmaier , Jon N. Eikenberry , Jerzy Z. Mydlarz , Nicholas E. Grzeskowiak
IPC分类号： G03C134
CPC分类号： G03C1/346 , G03C7/39236
摘要： This invention relates to a silver halide photographic element comprising at least one silver halide emulsion layer and further comprising an antifoggant represented by the following Structure I: wherein R1 is an aliphatic or cyclic group, R2 and R3 are independently hydrogen or bromine as long as at least one of them is bromine, L is a divalent linking group, m and n are independently 0 or 1, and SG is a solubilizing group that has a pKa of 8 or less.
摘要翻译：本发明涉及包含至少一个卤化银乳剂层的卤化银照相元件，并且还包含由以下结构I表示的防雾剂：其中R1是脂族或环状基团，R2和R3独立地是氢或溴，只要在其中至少一个是溴，L是二价连接基团，m和n独立地是0或1，SG是pKa为8或更低的增溶基团。

8. 发明授权

US06214529B1 Method of suppressing fog in silver halide emulsions 失效
标题翻译：抑制卤化银乳剂雾化的方法
公开(公告)号：US06214529B1
公开(公告)日：2001-04-10
申请号：US09416822
申请日：1999-10-12
申请人： Jon N. Eikenberry , Kenneth G. Harbison
发明人： Jon N. Eikenberry , Kenneth G. Harbison
IPC分类号： G03C518
CPC分类号： G03C1/34
摘要： This invention relates to a method of reducing fog in a silver halide emulsion comprising taking a high fogging emulsion which has been chemically sensitized and cooled, holding the high fogging emulsion in the form of a melt in preparation for coating on a support, and prior to or during said holding, contacting the emulsion with an isothiazolin-one compound represented by the following formula wherein R1 is a substituent; and Z contains the carbon atoms necessary to form a substituted or unsubstituted non-aromatic ring. It also relates to silver halide photographic elements containing such emulsions.
摘要翻译：本发明涉及一种减少卤化银乳剂雾化的方法，其包括采用化学增感和冷却的高雾化乳液，将高雾化乳液保持为熔体形式，以准备涂覆在载体上，并在或在所述保持期间，使乳液与由下列化学式表示的异噻唑啉一化合物接触，R1为取代基; 并且Z包含形成取代或未取代的非芳族环所必需的碳原子。它还涉及含有这种乳液的卤化银照相元件。

9. 发明授权

US5066376A Electrophoresis media comprising active methylene groups 失效
标题翻译：包含活性亚甲基的电泳介质
公开(公告)号：US5066376A
公开(公告)日：1991-11-19
申请号：US430998
申请日：1989-11-02
申请人： Hans W. Osterhoudt , Ignazio S. Ponticello , Kenneth G. Christy, Jr. , Wayne A. Bowman , Jon N. Eikenberry
发明人： Hans W. Osterhoudt , Ignazio S. Ponticello , Kenneth G. Christy, Jr. , Wayne A. Bowman , Jon N. Eikenberry
IPC分类号： G01N27/447
CPC分类号： G01N27/44747
摘要： A polyacrylamide type gel medium for electrophoresis is conveniently and safely prepared prior to use by crosslinking a water-soluble copolymer of an acrylamide monomer and at least one comonomer copolymerizable therewith, which comonomer contains an active methylene group that will enter into a crosslinking reaction that does not involve a free radical vinyl addition mechanism.
摘要翻译：用于电泳的聚丙烯酰胺型凝胶介质在使用前通过交联丙烯酰胺单体和至少一种可与其共聚的共聚单体的水溶性共聚物交联而方便和安全地制备，该共聚单体含有活性亚甲基，其将进入交联反应不涉及自由基乙烯基添加机理。

10. 发明授权

US4132528A Analytical element for the analysis of liquids under high pH conditions 失效
标题翻译：在高pH条件下分析液体的分析要素
公开(公告)号：US4132528A
公开(公告)日：1979-01-02
申请号：US866731
申请日：1978-01-03
申请人： Jon N. Eikenberry , Karl J. Sanford , Richard C. Sutton
发明人： Jon N. Eikenberry , Karl J. Sanford , Richard C. Sutton
IPC分类号： G01N31/22 , G01N33/48 , G01N33/52 , G01N33/68 , G01N33/16
CPC分类号： G01N33/525 , G01N33/6833
摘要： An improved analytical element for the detection of a predetermined analyte in an aqueous liquid under highly alkaline conditions is disclosed. The element features a stable, alkaline-providing composition.Preferably, the analytical element is a multi-zone element. The element is particularly useful in total protein analysis and, when so used, an improved biuret reagent composition for use therein is also provided. Methods of using the aforementioned analytical and biuret reagent composition are also disclosed.
摘要翻译：公开了用于在高碱性条件下检测水性液体中预定分析物的改进的分析元件。该元件具有稳定的碱性提供组合物。

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