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1. 发明申请

US20060138315A1 Method and system for calibrating a positron emission tomography system 有权
标题翻译：正电子发射断层扫描系统的校准方法和系统
公开(公告)号：US20060138315A1
公开(公告)日：2006-06-29
申请号：US11025233
申请日：2004-12-29
申请人： John Williams , Alexander Ganin , Charles Stearns , Yiping Shao , Floribertus Philippus Martinus Jansen , Ravindra Manjeshwar
发明人： John Williams , Alexander Ganin , Charles Stearns , Yiping Shao , Floribertus Philippus Martinus Jansen , Ravindra Manjeshwar
IPC分类号： G01T1/164
CPC分类号： G01T1/2985
摘要： Methods and systems for calibrating a positron emission tomography (PET) system are provided. The method includes determining at least one non-acquisition time period for the PET system. The method further includes automatically acquiring calibration data during the at least one non-acquisition time period.
摘要翻译：提供了用于校正正电子发射断层摄影（PET）系统的方法和系统。该方法包括确定PET系统的至少一个非获取时间段。所述方法还包括在所述至少一个非采集时段期间自动获取校准数据。

2. 发明申请

US20060145082A1 Method and system for positron emission tomography image reconstruction 有权
标题翻译：正电子发射断层扫描图像重建方法与系统
公开(公告)号：US20060145082A1
公开(公告)日：2006-07-06
申请号：US11026236
申请日：2004-12-30
申请人： Charles Stearns , David McDaniel , John Williams , Alexander Ganin , Ravindra Manjeshwar , Floribertus Philippus Heukensfeldt Jansen , Yiping Shao
发明人： Charles Stearns , David McDaniel , John Williams , Alexander Ganin , Ravindra Manjeshwar , Floribertus Philippus Heukensfeldt Jansen , Yiping Shao
IPC分类号： G01T1/164
CPC分类号： G01T1/2985
摘要： Methods and systems for controlling a positron emission tomography (PET) system are provided. The method includes receiving timing information from a PET system during an imaging scan using the PET system. The method further includes processing the received timing information and timing bias information relating to the PET system to control the PET system.
摘要翻译：提供了用于控制正电子发射断层摄影（PET）系统的方法和系统。该方法包括在使用PET系统的成像扫描期间从PET系统接收定时信息。该方法还包括处理接收到的定时信息和与PET系统有关的定时偏差信息以控制PET系统。

3. 发明申请

US20060097175A1 Method and system for imaging a patient 有权
公开(公告)号：US20060097175A1
公开(公告)日：2006-05-11
申请号：US10985752
申请日：2004-11-10
申请人： Alexander Ganin , Floribertus Philippus Martinus Jansen , Ricardo Avila , Dinko Eduardo Trotter , Ravindra Manjeshwar , James Miller , Thomas Sebastian
发明人： Alexander Ganin , Floribertus Philippus Martinus Jansen , Ricardo Avila , Dinko Eduardo Trotter , Ravindra Manjeshwar , James Miller , Thomas Sebastian
IPC分类号： G01T1/164
CPC分类号： G01T1/2985 , A61B6/037 , G01T1/1611 , G01T1/1615
摘要： Methods and systems for imaging a patient are provided. The method includes determining a location of a volume of interest within the patient and acquiring a plurality of frames of emission data, at least one frame including the volume of interest. The method further includes determining a time-of-flight (TOF) information of at least a portion of the annihilations detected along a line of response between corresponding coincidence detectors and generating an image of the patient from the emission data using the determined TOF information.

4. 发明申请

US20060151705A1 Method and system for scatter correction in a positron emission tomography system 有权
标题翻译：正电子发射断层扫描系统中散射校正的方法和系统
公开(公告)号：US20060151705A1
公开(公告)日：2006-07-13
申请号：US11034166
申请日：2005-01-12
申请人： Ravindra Manjeshwar , Floribertus Philippus Martinus Jansen , Charles Stearns
发明人： Ravindra Manjeshwar , Floribertus Philippus Martinus Jansen , Charles Stearns
IPC分类号： G01T1/164
CPC分类号： G01T1/2985 , A61B6/037
摘要： Methods and systems for providing scatter correction in a positron emission tomography (PET) system are provided. The method includes determining a look-up table of scatter sinograms during a PET acquisition scan period. The method further includes scatter correcting acquired scan data obtained during the PET acquisition scan period.
摘要翻译：提供了在正电子发射断层摄影（PET）系统中提供散射校正的方法和系统。该方法包括在PET采集扫描周期期间确定散射正弦图的查找表。该方法还包括在PET采集扫描周期期间获得的获取的扫描数据的散射校正。

5. 发明授权

US08131044B2 Method and apparatus for determining the effectiveness of an image transformation process 有权
标题翻译：用于确定图像变换过程的有效性的方法和装置
公开(公告)号：US08131044B2
公开(公告)日：2012-03-06
申请号：US12099261
申请日：2008-04-08
申请人： Scott David Wollenweber , Alexander Ganin , Ravindra Manjeshwar , Girishankar Gopalakrishnan , Evren Asma
发明人： Scott David Wollenweber , Alexander Ganin , Ravindra Manjeshwar , Girishankar Gopalakrishnan , Evren Asma
IPC分类号： A61B6/03
CPC分类号： G01T1/1611 , A61B6/032 , A61B6/037 , A61B6/508 , A61B6/5235 , A61B6/541 , G06T7/30 , G06T2207/10076 , G06T2207/10081 , G06T2207/10104 , G06T2207/30004
摘要： A method for determining the effectiveness of an image transformation process includes acquiring a four-dimensional (4D) image data set, sorting the 4D image data set into separate field-of-view bins using a temporal gating system generating a plurality of deformation vectors using the sorted 4D image data set, and using the plurality of deformation vectors to generate a transformation effectiveness value that is representative of the effectiveness of the image transformation process. The method further includes acquiring a respiratory signal, calculating a power spectrum of the respiratory signal, calculating a power spectrum for each of the plurality of deformation vectors, and comparing the power spectrum of the respiratory signal to the power spectrum of the plurality of deformation vectors to generate the transformation effectiveness value.
摘要翻译：一种用于确定图像变换过程的有效性的方法包括获取四维（4D）图像数据集，使用使用多个变形向量生成多个变形向量的时间门控系统将4D图像数据集排列成单独的视野区域分类的4D图像数据集，并且使用多个变形向量来生成代表图像变换处理的有效性的变换有效值。该方法还包括获取呼吸信号，计算呼吸信号的功率谱，计算多个变形矢量中的每一个的功率谱，并将呼吸信号的功率谱与多个变形矢量的功率谱进行比较以产生变换有效值。

6. 发明申请

US20090253980A1 METHOD AND APPARATUS FOR DETERMINING THE EFFECTIVENESS OF AN IMAGE TRANSFORMATION PROCESS 有权
标题翻译：用于确定图像变换过程的有效性的方法和装置
公开(公告)号：US20090253980A1
公开(公告)日：2009-10-08
申请号：US12099261
申请日：2008-04-08
申请人： Scott David Wollenweber , Alexander Ganin , Ravindra Manjeshwar , Girishankar Gopalakrishnan , Evren Asma
发明人： Scott David Wollenweber , Alexander Ganin , Ravindra Manjeshwar , Girishankar Gopalakrishnan , Evren Asma
IPC分类号： A61B5/05
CPC分类号： G01T1/1611 , A61B6/032 , A61B6/037 , A61B6/508 , A61B6/5235 , A61B6/541 , G06T7/30 , G06T2207/10076 , G06T2207/10081 , G06T2207/10104 , G06T2207/30004
摘要： A method for determining the effectiveness of an image transformation process includes acquiring a four-dimensional (4D) image data set, sorting the 4D image data set into separate field-of-view bins using a temporal gating system generating a plurality of deformation vectors using the sorted 4D image data set, and using the plurality of deformation vectors to generate a transformation effectiveness value that is representative of the effectiveness of the image transformation process. The method further includes acquiring a respiratory signal, calculating a power spectrum of the respiratory signal, calculating a power spectrum for each of the plurality of deformation vectors, and comparing the power spectrum of the respiratory signal to the power spectrum of the plurality of deformation vectors to generate the transformation effectiveness value.
摘要翻译：一种用于确定图像变换过程的有效性的方法包括获取四维（4D）图像数据集，使用使用多个变形向量生成多个变形向量的时间门控系统将4D图像数据集排列成单独的视野区域分类的4D图像数据集，并且使用多个变形向量来生成代表图像变换处理的有效性的变换有效值。该方法还包括获取呼吸信号，计算呼吸信号的功率谱，计算多个变形矢量中的每一个的功率谱，并将呼吸信号的功率谱与多个变形矢量的功率谱进行比较以产生变换有效值。

7. 发明申请

US20130248719A1 SYSTEMS AND METHODS FOR ATTENUATION COMPENSATION IN NUCLEAR MEDICINE IMAGING BASED ON EMISSION DATA 有权
标题翻译：基于排放数据的核医学成像中的衰减补偿系统与方法
公开(公告)号：US20130248719A1
公开(公告)日：2013-09-26
申请号：US13428840
申请日：2012-03-23
申请人： Lana Volokh , Yaron Hefetz , Alexander Ganin , Ravindra Manjeshwar
发明人： Lana Volokh , Yaron Hefetz , Alexander Ganin , Ravindra Manjeshwar
IPC分类号： G01T1/164
CPC分类号： A61B6/03 , A61B6/037 , A61B6/483 , A61B6/503 , A61B6/52 , A61B6/5205 , A61B6/5258 , A61B2576/023 , G06T11/005
摘要： Systems and methods for attenuation compensation in nuclear medicine imaging based on emission data are provided. One method includes acquiring emission data at a plurality of energy windows for a person having administered thereto a radiopharmaceutical comprising at least one radioactive isotope. The method also includes performing a preliminary reconstruction of the acquired emission data to create one or more preliminary images of a peak energy window and a scatter energy window and determining a body outline of the person from at least one of the reconstructed preliminary image of the peak energy window or of the scatter energy window. The method further includes identifying a heart contour and segmenting at least the left lung. The method additionally includes defining an attenuation map based on the body outline and segmented left lung and reconstructing an image of a region of interest of the person using an iterative joint estimation reconstruction.
摘要翻译：提供了基于发射数据的核医学成像中衰减补偿的系统和方法。一种方法包括在给予其的人的多个能量窗口上获取包含至少一种放射性同位素的放射性药物的排放数据。该方法还包括执行所获取的发射数据的初步重建以创建峰值能量窗口和散射能量窗口的一个或多个初步图像，并且从峰值的重建初步图像中的至少一个中确定人物轮廓线能量窗或散射能窗。所述方法还包括识别心脏轮廓并分割至少左肺。该方法还包括基于身体轮廓和分割的左肺定义衰减图，并且使用迭代联合估计重建来重建人的感兴趣区域的图像。

8. 发明授权

US08835858B2 Systems and methods for attenuation compensation in nuclear medicine imaging based on emission data 有权
标题翻译：基于排放数据的核医学成像中衰减补偿的系统和方法
公开(公告)号：US08835858B2
公开(公告)日：2014-09-16
申请号：US13428840
申请日：2012-03-23
申请人： Lana Volokh , Yaron Hefetz , Alexander Ganin , Ravindra Manjeshwar
发明人： Lana Volokh , Yaron Hefetz , Alexander Ganin , Ravindra Manjeshwar
IPC分类号： G01T1/164 , A61B6/00
CPC分类号： A61B6/03 , A61B6/037 , A61B6/483 , A61B6/503 , A61B6/52 , A61B6/5205 , A61B6/5258 , A61B2576/023 , G06T11/005
摘要： Systems and methods for attenuation compensation in nuclear medicine imaging based on emission data are provided. One method includes acquiring emission data at a plurality of energy windows for a person having administered thereto a radiopharmaceutical comprising at least one radioactive isotope. The method also includes performing a preliminary reconstruction of the acquired emission data to create one or more preliminary images of a peak energy window and a scatter energy window and determining a body outline of the person from at least one of the reconstructed preliminary image of the peak energy window or of the scatter energy window. The method further includes identifying a heart contour and segmenting at least the left lung. The method additionally includes defining an attenuation map based on the body outline and segmented left lung and reconstructing an image of a region of interest of the person using an iterative joint estimation reconstruction.
摘要翻译：提供了基于发射数据的核医学成像中衰减补偿的系统和方法。一种方法包括在给予其的人的多个能量窗口上获取包含至少一种放射性同位素的放射性药物的排放数据。该方法还包括执行所获取的排放数据的初步重建以创建峰值能量窗口和散射能量窗口的一个或多个初步图像，并且从峰值的重建初步图像中的至少一个中确定人物轮廓线能量窗或散射能窗。所述方法还包括识别心脏轮廓并分割至少左肺。该方法还包括基于身体轮廓和分割的左肺定义衰减图，并且使用迭代联合估计重建来重建人的感兴趣区域的图像。

9. 发明申请

US20060102846A1 METHOD AND SYSTEM FOR IMAGING USING A FILTER FOR TIME-OF-FLIGHT PET 失效
标题翻译：使用过滤器进行成像的方法和系统
公开(公告)号：US20060102846A1
公开(公告)日：2006-05-18
申请号：US10988878
申请日：2004-11-15
申请人： Ravindra Manjeshwar , Charles Stearns
发明人： Ravindra Manjeshwar , Charles Stearns
IPC分类号： G01T1/164
CPC分类号： G06T11/005
摘要： Methods and systems for imaging by using a filter for Time-Of-Flight Positron Emission Tomography (TOF PET) are described. The described methods of imaging a patient by using a positron emission tomography (PET) system includes acquiring a plurality of frames of sinogram data, filtering the acquired sinogram data and back-projecting the filtered sinogram data to form an output image of the patient. The acquired sinogram data defines a line of response (LOR) and a time-of-flight (TOF) measurement that localizes positron annihilation within the patient. The filtering of the acquired sinogram data is performed using the TOF measurement.
摘要翻译：描述了使用飞行时间正电子发射断层扫描（TOF PET）的滤波器进行成像的方法和系统。所描述的通过使用正电子发射断层摄影（PET）系统对患者进行成像的方法包括获取正弦图数据的多个帧，对所获取的正弦图数据进行滤波，以及反投影过滤的正弦图数据以形成患者的输出图像。获得的正中图数据定义了定位在患者体内的正电子湮灭的响应线（LOR）和飞行时间（TOF）测量。使用TOF测量来执行所获取的正弦图数据的滤波。

10. 发明申请

US20060261275A1 Method and system for reconstructing an image in a positron emission tomography (PET) system 有权
标题翻译：用于在正电子发射断层摄影（PET）系统中重建图像的方法和系统
公开(公告)号：US20060261275A1
公开(公告)日：2006-11-23
申请号：US11131149
申请日：2005-05-17
申请人： Charles Stearns , Ravindra Manjeshwar , Floribertus Philippus Heukensfeldt Jansen
发明人： Charles Stearns , Ravindra Manjeshwar , Floribertus Philippus Heukensfeldt Jansen
IPC分类号： G01T1/164
CPC分类号： G01T1/2985
摘要： A method and system for reconstructing an image in a time-of-flight (TOF) positron emission tomography (PET) system is provided. The method includes using a reconstructed image to determine predicted timing information. Timing bias data is updated based on received timing information associated with acquired scan data from a PET system and the predicted timing information. The method further includes reconstructing the image, based on the updated timing bias data.
摘要翻译：提供了一种用于在飞行时间（TOF）正电子发射断层摄影（PET）系统中重建图像的方法和系统。该方法包括使用重构图像来确定预测的定时信息。基于与来自PET系统的获取的扫描数据相关联的接收定时信息和预测的定时信息来更新定时偏差数据。该方法还包括基于更新的定时偏差数据重建图像。

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