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1. 发明授权

US08382689B2 Device and method for high intensity focused ultrasound ablation with acoustic lens 有权
标题翻译：声透镜高强度聚焦超声消融的装置和方法
公开(公告)号：US08382689B2
公开(公告)日：2013-02-26
申请号：US11703783
申请日：2007-02-08
申请人： John W. Sliwa , Peter Goetz , Zhenyi Ma , Jennifer Teng , Stephen Morse , Frank Callaghan , Timothy E. Ciciarelli
发明人： John W. Sliwa , Peter Goetz , Zhenyi Ma , Jennifer Teng , Stephen Morse , Frank Callaghan , Timothy E. Ciciarelli
IPC分类号： A61H1/00
CPC分类号： A61N7/02 , A61N2007/0056 , A61N2007/006 , A61N2007/0078
摘要： A high intensity focused ultrasound transducer includes an ultrasonic emitter having a surface that emits ultrasonic energy along a beam path, at least one low attenuation polymeric ultrasonic lens acoustically coupled to the surface in the beam path of the ultrasonic energy, such that the lens can direct the ultrasonic energy in at least one direction, and at least one stress mitigation feature, such as a kerf, a heat sink, or an acoustic matching layer, to mitigate thermal expansion mismatch stresses within the transducer. For manufacturing simplicity, the first surface is typically either flat or monotonically curvilinear. The lens may take a variety of shapes, including Fresnel features, and may focus, collimate, or defocus the ultrasonic energy. Any orientation and positioning of the at least one ultrasonic lens relative to the first ultrasonic emitter is contemplated. Manufacture is further simplified by molding, casting, or thermoforming the lens.
摘要翻译：高强度聚焦超声换能器包括具有沿着光束路径发射超声波能量的表面的超声波发射器，至少一个低衰减聚合物超声波透镜，声学耦合到超声能量的光束路径中的表面，使得透镜可以直接在至少一个方向上的超声波能量，以及至少一个应力消除特征，例如切口，散热器或声匹配层，以减轻换能器内的热膨胀失配应力。为了制造简单，第一表面通常是平坦的或单调曲线的。透镜可以采取各种形状，包括菲涅尔特征，并且可以聚焦，准直或散焦超声能量。考虑到相对于第一超声波发射器的至少一个超声波透镜的任何取向和定位。通过模制，铸造或热成型镜片进一步简化制造。

2. 发明授权

US08102734B2 High intensity focused ultrasound transducer with acoustic lens 有权
标题翻译：高强度聚焦超声波换能器与声透镜
公开(公告)号：US08102734B2
公开(公告)日：2012-01-24
申请号：US11703784
申请日：2007-02-08
申请人： John W. Sliwa , Peter Goetz , Zhenyi Ma , Jennifer Teng , Stephen Morse , Frank Callaghan , Timothy E. Ciciarelli
发明人： John W. Sliwa , Peter Goetz , Zhenyi Ma , Jennifer Teng , Stephen Morse , Frank Callaghan , Timothy E. Ciciarelli
IPC分类号： A61B8/00
CPC分类号： A61N7/02 , A61B8/4272 , A61B17/2251
摘要： A high intensity focused ultrasound transducer includes an ultrasonic emitter having a surface that emits ultrasonic energy along a beam path, at least one low attenuation polymeric ultrasonic lens acoustically coupled to the surface in the beam path of the ultrasonic energy, such that the lens can direct the ultrasonic energy in at least one direction, and at least one stress mitigation feature, such as a kerf, a heat sink, or an acoustic matching layer, to mitigate thermal expansion mismatch stresses within the transducer. For manufacturing simplicity, the first surface is typically either flat or monotonically curvilinear. The lens may take a variety of shapes, including Fresnel features, and may focus, collimate, or defocus the ultrasonic energy. Any orientation and positioning of the at least one ultrasonic lens relative to the first ultrasonic emitter is contemplated. Manufacture is further simplified by molding, casting, or thermoforming the lens.
摘要翻译：高强度聚焦超声换能器包括具有沿着光束路径发射超声波能量的表面的超声波发射器，至少一个低衰减聚合物超声波透镜，声学耦合到超声能量的光束路径中的表面，使得透镜可以直接在至少一个方向上的超声波能量，以及至少一个应力消除特征，例如切口，散热器或声匹配层，以减轻换能器内的热膨胀失配应力。为了制造简单，第一表面通常是平坦的或单调曲线的。透镜可以采取各种形状，包括菲涅尔特征，并且可以聚焦，准直或散焦超声能量。考虑到相对于第一超声波发射器的至少一个超声波透镜的任何取向和定位。通过模制，铸造或热成型镜片进一步简化制造。

3. 发明申请

US20080194967A1 High intensity focused ultrasound transducer with acoustic lens 有权
标题翻译：高强度聚焦超声波换能器与声透镜
公开(公告)号：US20080194967A1
公开(公告)日：2008-08-14
申请号：US11703784
申请日：2007-02-08
申请人： John W. Sliwa , Peter Goetz , Zhenyi Ma , Jennifer Teng , Stephen Morse , Frank Callaghan , Timothy E. Ciciarelli
发明人： John W. Sliwa , Peter Goetz , Zhenyi Ma , Jennifer Teng , Stephen Morse , Frank Callaghan , Timothy E. Ciciarelli
IPC分类号： A61B8/00
CPC分类号： A61N7/02 , A61B8/4272 , A61B17/2251
摘要： A high intensity focused ultrasound transducer includes an ultrasonic emitter having a surface that emits ultrasonic energy along a beam path, at least one low attenuation polymeric ultrasonic lens acoustically coupled to the surface in the beam path of the ultrasonic energy, such that the lens can direct the ultrasonic energy in at least one direction, and at least one stress mitigation feature, such as a kerf, a heat sink, or an acoustic matching layer, to mitigate thermal expansion mismatch stresses within the transducer. For manufacturing simplicity, the first surface is typically either flat or monotonically curvilinear. The lens may take a variety of shapes, including Fresnel features, and may focus, collimate, or defocus the ultrasonic energy. Any orientation and positioning of the at least one ultrasonic lens relative to the first ultrasonic emitter is contemplated. Manufacture is further simplified by molding, casting, or thermoforming the lens.
摘要翻译：高强度聚焦超声换能器包括具有沿着光束路径发射超声波能量的表面的超声波发射器，至少一个低衰减聚合物超声波透镜，声学耦合到超声能量的光束路径中的表面，使得透镜可以直接在至少一个方向上的超声波能量，以及至少一个应力消除特征，例如切口，散热器或声匹配层，以减轻换能器内的热膨胀失配应力。为了制造简单，第一表面通常是平坦的或单调曲线的。透镜可以采取各种形状，包括菲涅尔特征，并且可以聚焦，准直或散焦超声能量。考虑到相对于第一超声波发射器的至少一个超声波透镜的任何取向和定位。通过模制，铸造或热成型镜片进一步简化制造。

4. 发明申请

US20080194965A1 Device and method for high intensity focused ultrasound ablation with acoustic lens 有权
标题翻译：声透镜高强度聚焦超声消融的装置和方法
公开(公告)号：US20080194965A1
公开(公告)日：2008-08-14
申请号：US11703783
申请日：2007-02-08
申请人： John W. Sliwa , Peter Goetz , Zhenyi Ma , Jennifer Teng , Stephen Morse , Frank Callaghan , Timothy E. Ciciarelli
发明人： John W. Sliwa , Peter Goetz , Zhenyi Ma , Jennifer Teng , Stephen Morse , Frank Callaghan , Timothy E. Ciciarelli
IPC分类号： A61B17/00
CPC分类号： A61N7/02 , A61N2007/0056 , A61N2007/006 , A61N2007/0078
摘要： A high intensity focused ultrasound transducer includes an ultrasonic emitter having a surface that emits ultrasonic energy along a beam path, at least one low attenuation polymeric ultrasonic lens acoustically coupled to the surface in the beam path of the ultrasonic energy, such that the lens can direct the ultrasonic energy in at least one direction, and at least one stress mitigation feature, such as a kerf, a heat sink, or an acoustic matching layer, to mitigate thermal expansion mismatch stresses within the transducer. For manufacturing simplicity, the first surface is typically either flat or monotonically curvilinear. The lens may take a variety of shapes, including Fresnel features, and may focus, collimate, or defocus the ultrasonic energy. Any orientation and positioning of the at least one ultrasonic lens relative to the first ultrasonic emitter is contemplated. Manufacture is further simplified by molding, casting, or thermoforming the lens.
摘要翻译：高强度聚焦超声换能器包括具有沿着光束路径发射超声波能量的表面的超声波发射器，至少一个低衰减聚合物超声波透镜，声学耦合到超声能量的光束路径中的表面，使得透镜可以直接在至少一个方向上的超声波能量，以及至少一个应力消除特征，例如切口，散热器或声匹配层，以减轻换能器内的热膨胀失配应力。为了制造简单，第一表面通常是平坦的或单调曲线的。透镜可以采取各种形状，包括菲涅尔特征，并且可以聚焦，准直或散焦超声能量。考虑到相对于第一超声波发射器的至少一个超声波透镜的任何取向和定位。通过模制，铸造或热成型镜片进一步简化制造。

5. 发明授权

US09220524B2 Surgical tools to facilitate delivery of a neurostimulator into the pterygopalatine fossa 有权
标题翻译：手术工具，以便于神经刺激器输送到翼腭窝
公开(公告)号：US09220524B2
公开(公告)日：2015-12-29
申请号：US13470480
申请日：2012-05-14
申请人： Carl Lance Boling , Anthony V. Caparso , Francis A. Papay , Ryan Powell , Jennifer Teng , Morgan Clyburn
发明人： Carl Lance Boling , Anthony V. Caparso , Francis A. Papay , Ryan Powell , Jennifer Teng , Morgan Clyburn
IPC分类号： A61N1/05 , A61N1/36 , A61B17/24 , A61B17/02 , A61B17/3211 , A61B17/34 , A61B17/32 , A61N1/375
CPC分类号： A61B17/3468 , A61B17/02 , A61B17/0218 , A61B17/24 , A61B17/3211 , A61B2017/320052 , A61N1/0526 , A61N1/0548 , A61N1/0551 , A61N1/36075 , A61N1/37205 , A61N1/375
摘要： A surgical tool configured to facilitate delivery of a neurostimulator to a craniofacial region of a subject includes a handle portion, an elongate shaft having a contoured distal portion, and an insertion groove on the elongate shaft. The elongate shaft is configured to be advanced under a zygomatic bone along a maxillary tuberosity towards a pterygopalatine fossa. The distal portion includes a distal dissecting tip. The insertion groove is configured to receive, support, and guide a medical device or instrument.
摘要翻译：构造成便于将神经刺激器递送到受试者的颅面区域的手术工具包括手柄部分，具有轮廓远侧部分的细长轴和细长轴上的插入槽。细长轴构造成沿着上颌骨结节朝向翼腭窝向下延伸到z骨下方。远侧部分包括远端解剖尖端。插入槽被构造成接收，支撑和引导医疗装置或器械。

6. 发明申请

US20090163914A1 UNIVERSAL CELL CARRIER 失效
标题翻译：通用电池载体
公开(公告)号：US20090163914A1
公开(公告)日：2009-06-25
申请号：US11962913
申请日：2007-12-21
申请人： Andrew M. Radin , Thamas B. Eby , Vera S. Boudtchenko , Jennifer Teng , John P. Goetz , John E. Crowe
发明人： Andrew M. Radin , Thamas B. Eby , Vera S. Boudtchenko , Jennifer Teng , John P. Goetz , John E. Crowe
IPC分类号： A61B18/14
CPC分类号： A61B18/14 , A61B90/50 , A61B2018/00363 , A61B2018/00375 , A61N7/022
摘要： A carrier for an ablation element is provided. The carrier includes a plurality of walls defining a receiving portion configured to receive at least a portion of an ablation element. A plurality of connection formations are disposed on an exterior surface of least one of the plurality of walls. Each of the plurality of connection formations is disposed at a different vertical position of the carrier. A device for epicardial ablation is also provided. The device includes a plurality of carriers disposed adjacent to each other. Each carrier includes a plurality of walls defining a receiving portion configured to receive at least a portion of an ablation element. A plurality of connection formations are disposed on an exterior surface of at least one of the plurality of walls of each carrier. Each of the plurality of connection formations is disposed at a different vertical position of a carrier.
摘要翻译：提供用于消融元件的载体。载体包括限定被配置为接收消融元件的至少一部分的接收部分的多个壁。多个连接结构布置在多个壁中的至少一个壁的外表面上。多个连接结构中的每一个都布置在载体的不同垂直位置。还提供了用于心外膜消融的装置。该装置包括彼此相邻布置的多个载体。每个载体包括限定被配置为接收消融元件的至少一部分的接收部分的多个壁。多个连接结构布置在每个托架的多个壁中的至少一个的外表面上。多个连接结构中的每一个都设置在载体的不同垂直位置。

7. 发明授权

US08273083B2 Universal cell carrier 失效
标题翻译：通用电池载体
公开(公告)号：US08273083B2
公开(公告)日：2012-09-25
申请号：US11962913
申请日：2007-12-21
申请人： Andrew M. Radin , Thomas B. Eby , Vera S. Boudtchenka , Jennifer Teng , John P. Goetz , John E. Crowe
发明人： Andrew M. Radin , Thomas B. Eby , Vera S. Boudtchenka , Jennifer Teng , John P. Goetz , John E. Crowe
IPC分类号： A61B18/14
CPC分类号： A61B18/14 , A61B90/50 , A61B2018/00363 , A61B2018/00375 , A61N7/022
摘要： A carrier for an ablation element is provided. The carrier includes a plurality of walls defining a receiving portion configured to receive at least a portion of an ablation element. A plurality of connection formations are disposed on an exterior surface of least one of the plurality of walls. Each of the plurality of connection formations is disposed at a different vertical position of the carrier. A device for epicardial ablation is also provided. The device includes a plurality of carriers disposed adjacent to each other. Each carrier includes a plurality of walls defining a receiving portion configured to receive at least a portion of an ablation element. A plurality of connection formations are disposed on an exterior surface of at least one of the plurality of walls of each carrier. Each of the plurality of connection formations is disposed at a different vertical position of a carrier.
摘要翻译：提供用于消融元件的载体。载体包括限定被配置为接收消融元件的至少一部分的接收部分的多个壁。多个连接结构布置在多个壁中的至少一个壁的外表面上。多个连接结构中的每一个都布置在载体的不同垂直位置。还提供了用于心外膜消融的装置。该装置包括彼此相邻布置的多个载体。每个载体包括限定被配置为接收消融元件的至少一部分的接收部分的多个壁。多个连接结构布置在每个托架的多个壁中的至少一个的外表面上。多个连接结构中的每一个都设置在载体的不同垂直位置。

8. 发明授权

US09370396B2 Transition apparatus for use with a medical device having an elongate element 有权
标题翻译：与具有细长元件的医疗装置一起使用的过渡装置
公开(公告)号：US09370396B2
公开(公告)日：2016-06-21
申请号：US11964158
申请日：2007-12-26
申请人： Andrew M. Radin , Thomas B. Eby , Vera S. Boudtchenko , Jennifer Teng , John P. Goetz
发明人： Andrew M. Radin , Thomas B. Eby , Vera S. Boudtchenko , Jennifer Teng , John P. Goetz
IPC分类号： A61B18/14 , A61B18/00
CPC分类号： A61B18/1492 , A61B90/50 , A61B2018/00363 , A61B2018/00375 , A61B2018/00577
摘要： A transition apparatus for use with a medical device having an elongate element is disclosed. The apparatus may include a body defining a lumen for housing at least a portion of the elongate element. The body may have a proximal end configured for releasable connection to the medical device and a distal end. The apparatus may further include a connection piece connected to the distal end of the body. The connection piece may have a first opening configured to receive the elongate element from the lumen of the body and a second opening configured to receive the elongate element from the first opening and direct the elongate element toward the body. A method of connecting a transition apparatus to an ablation device having a leash is also disclosed.
摘要翻译：公开了一种与具有细长元件的医疗装置一起使用的过渡装置。该装置可以包括限定用于容纳细长元件的至少一部分的内腔的主体。主体可以具有构造成用于可释放地连接到医疗装置和远端的近端。该装置还可以包括连接到主体的远端的连接件。连接件可以具有构造成从主体的内腔接收细长元件的第一开口和被配置为从第一开口接纳细长元件并将细长元件引向主体的第二开口。还公开了一种将过渡装置连接到具有皮带的消融装置的方法。

9. 发明申请

US20120277761A1 SURGICAL TOOLS TO FACILITATE DELIVERY OF A NEUROSTIMULATOR INTO THE PTERYGOPALATINE FOSSA 有权
标题翻译：手术工具，以便将神经调节剂输送到PASGGALALATINE FOSSA
公开(公告)号：US20120277761A1
公开(公告)日：2012-11-01
申请号：US13470480
申请日：2012-05-14
申请人： Carl Lance Boling , Anthony V. Caparso , Francis A. Papay , Ryan Powell , Jennifer Teng , Morgan Clyburn
发明人： Carl Lance Boling , Anthony V. Caparso , Francis A. Papay , Ryan Powell , Jennifer Teng , Morgan Clyburn
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61B17/3468 , A61B17/02 , A61B17/0218 , A61B17/24 , A61B17/3211 , A61B2017/320052 , A61N1/0526 , A61N1/0548 , A61N1/0551 , A61N1/36075 , A61N1/37205 , A61N1/375
摘要： A surgical tool configured to facilitate delivery of a neurostimulator to a craniofacial region of a subject includes a handle portion, an elongate shaft having a contoured distal portion, and an insertion groove on the elongate shaft. The elongate shaft is configured to be advanced under a zygomatic bone along a maxillary tuberosity towards a pterygopalatine fossa. The distal portion includes a distal dissecting tip. The insertion groove is configured to receive, support, and guide a medical device or instrument.
摘要翻译：构造成便于将神经刺激器递送到受试者的颅面区域的手术工具包括手柄部分，具有轮廓远侧部分的细长轴和细长轴上的插入槽。细长轴构造成沿着上颌骨结节朝向翼腭窝向下延伸到z骨下方。远侧部分包括远端解剖尖端。插入槽被构造成接收，支撑和引导医疗装置或器械。

10. 发明申请

US20090171347A1 TRANSITION APPARATUS FOR USE WITH A MEDICAL DEVICE HAVING AN ELONGATE ELEMENT 有权
标题翻译：用于具有长耳元件的医疗装置的过渡装置
公开(公告)号：US20090171347A1
公开(公告)日：2009-07-02
申请号：US11964158
申请日：2007-12-26
申请人： Andrew M. Radin , Thomas B. Eby , Vera S. Boudtchenko , Jennifer Teng , John P. Goetz
发明人： Andrew M. Radin , Thomas B. Eby , Vera S. Boudtchenko , Jennifer Teng , John P. Goetz
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B90/50 , A61B2018/00363 , A61B2018/00375 , A61B2018/00577
摘要： A transition apparatus for use with a medical device having an elongate element is disclosed. The apparatus may include a body defining a lumen for housing at least a portion of the elongate element. The body may have a proximal end configured for releasable connection to the medical device and a distal end. The apparatus may further include a connection piece connected to the distal end of the body. The connection piece may have a first opening configured to receive the elongate element from the lumen of the body and a second opening configured to receive the elongate element from the first opening and direct the elongate element toward the body. A method of connecting a transition apparatus to an ablation device having a leash is also disclosed.
摘要翻译：公开了一种与具有细长元件的医疗装置一起使用的过渡装置。该装置可以包括限定用于容纳细长元件的至少一部分的内腔的主体。主体可以具有构造成用于可释放地连接到医疗装置和远端的近端。该装置还可以包括连接到主体的远端的连接件。连接件可以具有构造成从主体的内腔接收细长元件的第一开口和被配置为从第一开口接纳细长元件并将细长元件引向主体的第二开口。还公开了一种将过渡装置连接到具有皮带的消融装置的方法。

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