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1. 发明授权

US6024704A Implantable medical device for sensing absolute blood pressure and barometric pressure 失效
标题翻译：用于感测绝对血压和大气压力的植入式医疗装置
公开(公告)号：US6024704A
公开(公告)日：2000-02-15
申请号：US70310
申请日：1998-04-30
申请人： John T. Meador , Keith A. Miesel , Louis E. Halperin , Robert T. Taepke, II , Lee Stylos
发明人： John T. Meador , Keith A. Miesel , Louis E. Halperin , Robert T. Taepke, II , Lee Stylos
IPC分类号： A61B5/0215 , A61B5/03 , A61B5/02
CPC分类号： A61B5/0215 , A61B5/03 , A61B2560/0257 , A61M1/122 , A61M2205/702
摘要： An implantable barometric pressure sensor coupled with an implantable medical device (IMD) provides a barometric pressure related, reference pressure value for use in combination with an absolute pressure value measured by an implantable absolute pressure sensor coupled to the IMD. In one embodiment, the barometric pressure sensor is implanted under the skin and subcutaneous tissue layer at or near the implant site of the IMD. In variations of this embodiment, the barometric pressure is formed as part of a connector module of the IMD or extends from the connector module. In a further embodiment, a percutaneous access device is provided which is adapted to be implanted to extend through the skin and subcutaneous tissue layer of the patient and is coupled with the barometric pressure sensor to provide for an air chamber extending between the atmosphere and the barometric pressure sensor. The barometric pressure sensor is preferably enclosed within an air chamber of the implantable medical device, and a catheter extends between the air chamber of the implantable medical device and the percutaneous access device. Or the barometric pressure sensor is enclosed within an air chamber of the percutaneous access device, and a lead extends between the barometric pressure sensor and the implantable medical device.
摘要翻译：与可植入医疗装置（IMD）耦合的可植入气压传感器提供与大气压相关的参考压力值，与由耦合到IMD的可植入绝对压力传感器测量的绝对压力值组合使用。在一个实施例中，将大气压力传感器植入在IMD的植入部位处或附近的皮肤和皮下组织层下方。在该实施例的变型中，大气压力形成为IMD的连接器模块的一部分或者从连接器模块延伸。在另一个实施例中，提供经皮进入装置，其适于植入以延伸通过患者的皮肤和皮下组织层，并与大气压力传感器耦合以提供在大气和气压之间延伸的空气室压力传感器。大气压力传感器优选地封装在可植入医疗装置的空气室内，并且导管在可植入医疗装置的空气室和经皮进入装置之间延伸。或者气压传感器被封闭在经皮进入装置的气室中，并且引线在大气压力传感器和可植入医疗装置之间延伸。

2. 发明授权

US06234973B1 Implantable medical device for sensing absolute blood pressure and barometric pressure 有权
标题翻译：用于感测绝对血压和大气压力的植入式医疗装置
公开(公告)号：US06234973B1
公开(公告)日：2001-05-22
申请号：US09442855
申请日：1999-11-18
申请人： John T. Meador , Keith A. Miesel , Louis E. Halperin , Robert T. Taepke, II , Lee Stylos
发明人： John T. Meador , Keith A. Miesel , Louis E. Halperin , Robert T. Taepke, II , Lee Stylos
IPC分类号： A61B502
CPC分类号： A61B5/0215 , A61B5/03 , A61B2560/0257 , A61M1/1086 , A61M1/12 , A61M1/122 , A61M2205/702
摘要： An implantable barometric pressure sensor coupled with an implantable medical device (IMD) provides a barometric pressure related, reference pressure value for use in combination with an absolute pressure value measured by an implantable absolute pressure sensor coupled to the IMD. In one embodiment, the barometric pressure sensor is implanted under the skin and subcutaneous tissue layer at or near the implant site of the IMD. In variations of this embodiment, the barometric pressure is formed as part of a connector module of the IMD or extends from the connector module. In a further embodiment, a percutaneous access device is provided which is adapted to be implanted to extend through the skin and subcutaneous tissue layer of the patient and is coupled with the barometric pressure sensor to provide for an air chamber extending between the atmosphere and the barometric pressure sensor. The barometric pressure sensor is preferably enclosed within an air chamber of the implantable medical device, and a catheter extends between the air chamber of the implantable medical device and the percutaneous access device. Or the barometric pressure sensor is enclosed within an air chamber of the percutaneous access device, and a lead extends between the barometric pressure sensor and the implantable medical device.
摘要翻译：与可植入医疗装置（IMD）耦合的可植入气压传感器提供与大气压相关的参考压力值，与由耦合到IMD的可植入绝对压力传感器测量的绝对压力值组合使用。在一个实施例中，将大气压力传感器植入在IMD的植入部位处或附近的皮肤和皮下组织层下方。在该实施例的变型中，大气压力形成为IMD的连接器模块的一部分或者从连接器模块延伸。在另一个实施例中，提供经皮进入装置，其适于植入以延伸通过患者的皮肤和皮下组织层，并与大气压力传感器耦合以提供在大气和气压之间延伸的空气室压力传感器。大气压力传感器优选地封装在可植入医疗装置的空气室内，并且导管在可植入医疗装置的空气室和经皮进入装置之间延伸。或者气压传感器被封闭在经皮进入装置的气室中，并且引线在大气压力传感器和可植入医疗装置之间延伸。

3. 发明授权

US5336253A Pacing and cardioversion lead systems with shared lead conductors 失效
标题翻译：起搏和心脏复律引导系统具有共用引线导体
公开(公告)号：US5336253A
公开(公告)日：1994-08-09
申请号：US21408
申请日：1993-02-23
申请人： Pat L. Gordon , John T. Meador , John G. Keimel , Rahul Mehra
发明人： Pat L. Gordon , John T. Meador , John G. Keimel , Rahul Mehra
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： A combined pacing and cardioversion lead system with internal electrical switching components for unipolar or bipolar sensing of electrograms, pacing at normal pacing voltages and cardioversion or defibrillation. In bipolar embodiments, an indifferent electrode, closely spaced to a sensing and pacing electrode, is coupled in common through the integral switching circuitry to a large surface area cardioversion electrode. In these embodiments, pacing and sensing is accomplished through a pair of conductors extending through the lead system to the closely spaced active and indifferent electrode pair. When cardioversion energy is applied to the indifferent electrode, the cardioversion energy is also directed to the cardioversion electrode through operation of the switching circuitry in response to the magnitude of the applied cardioversion pulse. In unipolar embodiments, a distal sensing and pacing electrode is coupled through integral switching circuitry to a large surface area cardioversion electrode. In these embodiments, only a single conductor extending through the lead to the pacing and sensing electrode is required. When cardioversion energy is applied to the pacing and sensing electrode, the cardioversion energy is also directed to the cardioversion electrode through operation of the switching circuitry in response to the magnitude of the applied cardioversion pulse.
摘要翻译：组合起搏和心律转复引导系统，具有用于单极或双极感测电描记图，起搏正常起搏电压和心脏复律或除颤的内部电气开关组件。在双极实施例中，与感测和起搏电极紧密隔开的无关电极通过整体开关电路共同耦合到大表面积的复律电极。在这些实施例中，起搏和感测通过一对延伸穿过导线系统的导体实现到紧密间隔的有源和无关电极对。当心脏复律能量被施加到无关电极时，响应于所应用的心脏复律脉冲的幅度，复律能量也通过开关电路的操作而被引导到心脏复律电极。在单极实施例中，远端感测和起搏电极通过整体开关电路耦合到大表面积的心脏复律电极。在这些实施例中，仅需要将穿过引线延伸到起搏和感测电极的单个导体。当心律转换能量被施加到起搏和感测电极时，响应于所应用的心律转复脉冲的幅度，复律能量也通过开关电路的操作而被引导到心脏复律电极。

4. 发明授权

US5713929A Arrhythmia and fibrillation prevention pacemaker using ratchet up and decay modes of operation 失效
标题翻译：心律失常和颤动预防起搏器采用棘轮和衰减手术方式
公开(公告)号：US5713929A
公开(公告)日：1998-02-03
申请号：US642717
申请日：1996-05-03
申请人： Michael F. Hess , Michael R. S. Hill , John T. Meador , R. Hardwin Mead
发明人： Michael F. Hess , Michael R. S. Hill , John T. Meador , R. Hardwin Mead
IPC分类号： A61N1/368 , A61N1/362 , A61N1/39
CPC分类号： A61N1/3622
摘要： New pacing algorithm defines faster than indicated pacing rate during detection of PAC's/PVC's and reduces rate after awhile to a safety rate unless natural depolarizations are detected.
摘要翻译：新的起搏算法在PAC / PVC检测过程中定义比指定的起搏速度更快，并且在一段时间后将速率降低到安全速率，除非检测到自然去极化。

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