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1. 发明授权

US06311004B1 Photonic devices comprising thermo-optic polymer 有权
标题翻译：包含热光聚合物的光子器件
公开(公告)号：US06311004B1
公开(公告)日：2001-10-30
申请号：US09437690
申请日：1999-11-10
申请人： John T. Kenney , John Midgley , Valentine N. Morozov , Ken Purchase , Marc Stiller , Anthony Ticknor , James Burke , John Love
发明人： John T. Kenney , John Midgley , Valentine N. Morozov , Ken Purchase , Marc Stiller , Anthony Ticknor , James Burke , John Love
IPC分类号： G02B610
CPC分类号： G02B6/12011 , G02B6/02066 , G02B6/12026 , G02B2006/12061 , G02B2006/12069 , G02B2006/12097 , G02B2006/12107 , G02B2006/12109 , G02F1/011 , G02F1/0147 , G02F1/065 , G02F2001/0113 , G02F2203/055
摘要： Hybrid integrated planar photonics provides silica waveguides for transport and polymer or hybrid silica/polymer waveguides for refractive-based active functions within a single integrated photonic circuit. Functions include modulation, attenuation, switching, filtering, and exceptionally low-loss transport. When the active and passive optical elements are integrated onto the same substrates, the resulting composite devices can exhibit strong functional response with little total optical loss as compared to known methods.
摘要翻译：混合集成平面光子学提供用于传输的二氧化硅波导和用于单个集成光子电路内用于基于折射的有源功能的聚合物或混合二氧化硅/聚合物波导。功能包括调制，衰减，切换，滤波和异常低损耗的传输。当有源和无源光学元件集成在相同的基板上时，与已知的方法相比，所得到的复合器件可以表现出强的功能响应，几乎没有总的光损耗。

2. 发明授权

US08820287B2 Supplementary energy starting system incorporating a timing circuit 有权
标题翻译：补充能量启动系统并入定时电路
公开(公告)号：US08820287B2
公开(公告)日：2014-09-02
申请号：US13400254
申请日：2012-02-20
申请人： Dean Solberg , James Burke
发明人： Dean Solberg , James Burke
IPC分类号： F02N11/08
CPC分类号： F02N11/0866
摘要： An engine cranking system and a method of cranking an engine are provided. The engine cranking system comprises an engine, cranking motor, and capacitor. The engine cranking system further comprises an electrical path interconnecting the cranking motor or a battery to the capacitor. The engine cranking system further comprises a control circuit coupled to the capacitor. The control circuit comprises a timer operative to track temporal information. The control circuit is operative to apply a control voltage that varies in response to the tracked temporal information. The control circuit further comprises a relay included in the electrical path. The relay is operative to switch, in response to the control voltage, between an open-circuit condition, in which the relay interrupts the electrical path, and a closed-circuit condition.
摘要翻译：提供一种发动机起动系统和起动发动机的方法。发动机起动系统包括发动机，起动马达和电容器。发动机起动系统还包括将起动马达或电池互连到电容器的电气路径。发动机起动系统还包括耦合到电容器的控制电路。控制电路包括用于跟踪时间信息的定时器。控制电路可操作以施加响应于跟踪的时间信息而变化的控制电压。控制电路还包括包含在电路径中的继电器。继电器可操作以响应于控制电压在继电器中断电路径的开路状态与闭路状态之间切换。

3. 发明授权

US08425929B2 Sustained release intraocular implants and methods for preventing retinal dysfunction 有权
公开(公告)号：US08425929B2
公开(公告)日：2013-04-23
申请号：US10837143
申请日：2004-04-30
申请人： Glenn T. Huang , James Burke , Patrick M. Hughes , Kai-Ming Zhang , Ton Lin , Larry A. Wheeler , Rosy Sheng Donn
发明人： Glenn T. Huang , James Burke , Patrick M. Hughes , Kai-Ming Zhang , Ton Lin , Larry A. Wheeler , Rosy Sheng Donn
IPC分类号： A61F2/02
CPC分类号： A61K31/498 , A61K9/0051 , A61K47/34
摘要： Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to prevent the occurrence of one or more ocular conditions, or to reduce one or more symptoms of an ocular condition, such as an ocular neurosensory disorder and the like.

4. 发明申请

US20080131372A1 SUSTAINED RELEASE INTRAOCULAR IMPLANTS AND METHODS FOR PREVENTING RETINAL DYSFUNCTION 有权
标题翻译：可持续释放内镜植入物和预防后遗症的方法
公开(公告)号：US20080131372A1
公开(公告)日：2008-06-05
申请号：US11927615
申请日：2007-10-29
申请人： Glenn T. Huang , James Burke , Patrick M. Hughes , Kai-Ming Zhang , Ton Lin , Larry A. Wheeler , Rosy Sheng Donn
发明人： Glenn T. Huang , James Burke , Patrick M. Hughes , Kai-Ming Zhang , Ton Lin , Larry A. Wheeler , Rosy Sheng Donn
IPC分类号： A61K31/498 , A61P27/16
CPC分类号： A61K31/498 , A61K9/0051 , A61K47/34
摘要： Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to prevent the occurrence of one or more ocular conditions, or to reduce one or more symptoms of an ocular condition, such as an ocular neurosensory disorder and the like.
摘要翻译：生物相容性眼内植入物包括α-2肾上腺素能受体激动剂和与α-2肾上腺素能受体激动剂相关的聚合物，以促进α-2肾上腺素能受体激动剂延长一段时间的眼睛释放。 α-2肾上腺素能受体激动剂可以与可生物降解的聚合物基质例如两种可生物降解的聚合物的基质相关联。植入物可以放置在眼睛中以防止发生一种或多种眼部病症，或者减少眼部疾病如眼睛神经感觉障碍等的一种或多种症状。

5. 发明申请

US20080118549A1 SUSTAINED RELEASE INTRAOCULAR IMPLANTS AND METHODS FOR TREATING OCULAR VASCULOPATHIES 有权
标题翻译：可持续发布的内窥镜植入物和治疗卵巢血管病的方法
公开(公告)号：US20080118549A1
公开(公告)日：2008-05-22
申请号：US12024017
申请日：2008-01-31
申请人： Glenn HUANG , Brittany Jackson , James Burke , Ton Lin , Patrick Hughes , Larry Wheeler , Rosy Donn
发明人： Glenn HUANG , Brittany Jackson , James Burke , Ton Lin , Patrick Hughes , Larry Wheeler , Rosy Donn
IPC分类号： A61K9/00 , A61K31/502 , A61P27/16
CPC分类号： A61L31/148 , A61K9/0051 , A61K9/204 , A61K31/498 , A61K47/34 , A61L27/58 , A61L31/06 , A61L31/16 , A61L2300/436 , A61L2300/604 , C08L67/04 , Y02A50/401
摘要： Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to treat one or more ocular conditions, such as an ocular vasculopathy or glaucoma, among others.
摘要翻译：生物相容性眼内植入物包括α-2肾上腺素能受体激动剂和与α-2肾上腺素能受体激动剂相关的聚合物，以促进α-2肾上腺素能受体激动剂延长一段时间的眼睛释放。 α-2肾上腺素能受体激动剂可以与可生物降解的聚合物基质例如两种可生物降解的聚合物的基质相关联。植入物可以放置在眼睛中以治疗一种或多种眼部病症，例如眼睛血管病变或青光眼等。

6. 发明申请

US20080118548A1 SUSTAINED RELEASE INTRAOCULAR IMPLANTS AND METHODS FOR TREATING OCULAR VASCULOPATHIES 有权
公开(公告)号：US20080118548A1
公开(公告)日：2008-05-22
申请号：US12024014
申请日：2008-01-31
申请人： Glenn HUANG , Brittany Jackson , James Burke , Ton Lin , Patrick Hughes , Larry Wheeler , Rosy Donn
发明人： Glenn HUANG , Brittany Jackson , James Burke , Ton Lin , Patrick Hughes , Larry Wheeler , Rosy Donn
IPC分类号： A61K9/00 , A61P27/16
CPC分类号： A61L31/148 , A61K9/0051 , A61K9/204 , A61K31/498 , A61K47/34 , A61L27/58 , A61L31/06 , A61L31/16 , A61L2300/436 , A61L2300/604 , C08L67/04 , Y02A50/401
摘要： Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to treat one or more ocular conditions, such as an ocular vasculopathy or glaucoma, among others.

7. 发明申请

US20080118547A1 SUSTAINED RELEASE INTRAOCULAR IMPLANTS AND METHODS FOR TREATING OCULAR VASCULOPATHIES 有权
公开(公告)号：US20080118547A1
公开(公告)日：2008-05-22
申请号：US12024010
申请日：2008-01-31
申请人： Glenn Huang , Brittany Jackson , James Burke , Ton Lin , Patrick Hughes , Larry Wheeler , Rosy Donn
发明人： Glenn Huang , Brittany Jackson , James Burke , Ton Lin , Patrick Hughes , Larry Wheeler , Rosy Donn
IPC分类号： A61K9/00
CPC分类号： A61L31/148 , A61K9/0051 , A61K9/204 , A61K31/498 , A61K47/34 , A61L27/58 , A61L31/06 , A61L31/16 , A61L2300/436 , A61L2300/604 , C08L67/04 , Y02A50/401
摘要： Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to treat one or more ocular conditions, such as an ocular vasculopathy or glaucoma, among others.

8. 发明申请

US20080112923A1 OCULAR THERAPY USING ALPHA-2 ADRENERGIC RECEPTOR ANTERIOR COMPOUNDS HAVING ENHANCED CLEARANCE RATES 审中-公开
公开(公告)号：US20080112923A1
公开(公告)日：2008-05-15
申请号：US11949751
申请日：2007-12-03
申请人： Patrick HUGHES , James Burke , Joan-En Chang-Lin
发明人： Patrick HUGHES , James Burke , Joan-En Chang-Lin
IPC分类号： A61K31/765
CPC分类号： A61K9/0051 , A61K9/0048 , A61K9/1647
摘要： Ophthalmically therapeutic materials, such as liquid-containing compositions and polymeric drug delivery systems, include a therapeutic component which includes an alpha 2 adrenergic receptor agonist that is cleared from the anterior segment of an individual's eye to which the material is administered. The alpha 2 adrenergic receptor agonist may have a vitreal half-life greater than about three hours. The present materials are effective in treating an ocular condition(s) that affect the anterior segment of an eye, or the anterior and posterior segment of the eye. The materials are suitable for intravitreal or periocular administration and can provide prolonged drug delivery and therapeutic benefits to patients to which the materials have been administered. The alpha 2 adrenergic receptor agonists can be provided in liquid-containing formulations and/or bioerodible and/or non-bioerodible polymeric implants and microparticles. Methods of making and using the present materials are also described.

9. 发明申请

US20070148208A1 ANTI-EXCITITOXIC SUSTAINED RELEASE INTRACULAR IMPLANTS AND RELATED METHODS 审中-公开
标题翻译：抗真菌持续释放入侵植入物及相关方法
公开(公告)号：US20070148208A1
公开(公告)日：2007-06-28
申请号：US11680615
申请日：2007-02-28
申请人： Patrick Hughes , James Burke , Rhett Schiffman
发明人： Patrick Hughes , James Burke , Rhett Schiffman
IPC分类号： A61F2/02 , A61K31/13
CPC分类号： A61K9/0051
摘要： Biocompatible intraocular implants include an anti-excitotoxic agent and a biodegradable polymer that is effective to facilitate release of the anti-excitotoxic agent into an eye for an extended period of time. The therapeutic agents of the implants may be associated with a biodegradable polymer matrix, such as a matrix that is substantially free of a polyvinyl alcohol. The implants may be placed in an eye to treat or reduce the occurrence of one or more ocular conditions, such as retinal damage, including glaucoma and proliferative vitreoretinopathy.
摘要翻译：生物相容性眼内植入物包括抗兴奋性毒性剂和可生物降解的聚合物，其有效促进抗兴奋性毒性剂长时间释放到眼睛中。植入物的治疗剂可以与可生物降解的聚合物基质相关，例如基本上不含聚乙烯醇的基质。植入物可以放置在眼睛中以治疗或减少一种或多种眼部病症的发生，例如视网膜损伤，包括青光眼和增生性玻璃体视网膜病变。

10. 发明申请

US20070129711A1 Cooling system for a photocosmetic device 有权
标题翻译：光学设备的冷却系统
公开(公告)号：US20070129711A1
公开(公告)日：2007-06-07
申请号：US11603712
申请日：2006-11-22
申请人： Gregory Altshuler , Joseph Caruso , Henry Zenzie , James Burke , Andrei Erofeev
发明人： Gregory Altshuler , Joseph Caruso , Henry Zenzie , James Burke , Andrei Erofeev
IPC分类号： A61B18/18
CPC分类号： A61B5/0077 , A45D26/0061 , A45D44/005 , A61B18/203 , A61B2017/00026 , A61B2017/00747 , A61B2017/00765 , A61B2017/00769 , A61B2018/00011 , A61B2018/00029 , A61B2018/00452 , A61B2018/00476 , A61B2018/00904 , A61B2090/065 , A61N1/328
摘要： Photocosmetic device for use in medical or non-medical environments (e.g., a home, barbershop, or spa), which can be used for a variety of tissue treatments. Radiation is delivered to the tissue via optical systems designed to pattern the radiation and project the radiation to a particular depth. The device has a variety of cooling systems including phase change cooling solids and liquids to cool treated skin and the radiation sources. Contact sensors and motion sensor may be used to enhance treatment. The device may be modular to facilitate manufacture and replacement of parts.
摘要翻译：用于医疗或非医疗环境（例如，家庭，理发店或温泉）的光学设备，其可用于各种组织处理。辐射通过设计成对辐射进行图案化并将辐射投射到特定深度的光学系统传送到组织。该装置具有各种冷却系统，包括相变冷却固体和液体以冷却经处理的皮肤和辐射源。接触传感器和运动传感器可用于增强治疗。该装置可以是模块化的，以便于部件的制造和更换。

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