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1. 发明申请

US20070238656A1 Functionalized poly(ethylene glycol) 审中-公开
标题翻译：官能化聚（乙二醇）
公开(公告)号：US20070238656A1
公开(公告)日：2007-10-11
申请号：US11400935
申请日：2006-04-10
申请人： John Harder , Jeffrey Leon
发明人： John Harder , Jeffrey Leon
IPC分类号： A61K38/00
CPC分类号： C08G65/329 , C08G65/334 , C08G65/3344 , C08G65/3348
摘要： The present invention relates to a bi-functional compound containing a linking material, and a particle comprising a linking material, and a linking material comprising a polyethylene glycol macromonomer backbone with a radical polymerizable group at one end of the macromonomer backbone and a different reactive chemical functionality at the other end of the macromonomer backbone, according to Formula I: wherein X is CH3, CN or H; Y is O, NR1, or S; L is a linking group or spacer; FG is a functional group; n is greater than 4 and less than 1000; and wherein R1 and R2 are independently selected from substituted or unsubstituted alkyl, aryl, or heteroyl.
摘要翻译：本发明涉及包含连接材料的双功能化合物和包含连接材料的颗粒，以及包含在大分子单体骨架的一端具有自由基聚合性基团的聚乙二醇大分子单体骨架和不同的反应性化学物质的连接材料在大分子单体骨架的另一端的官能团，根据式I：其中X是CH 3，CN或H; Y是O，NR 1或S; L是连接基团或间隔基; FG是功能组; n大于4且小于1000; 并且其中R 1和R 2独立地选自取代或未取代的烷基，芳基或杂基。

2. 发明申请

US20070237821A1 Nanogel-based contrast agents for optical molecular imaging 审中-公开
标题翻译：基于Nanogel的光学分子成像造影剂
公开(公告)号：US20070237821A1
公开(公告)日：2007-10-11
申请号：US11401343
申请日：2006-04-10
申请人： Jeffrey Leon , James Bennett , Tiecheng Qiao , John Harder , Thomas Mourey , Gary Slater , Lijun Dai
发明人： Jeffrey Leon , James Bennett , Tiecheng Qiao , John Harder , Thomas Mourey , Gary Slater , Lijun Dai
IPC分类号： A61K9/14
CPC分类号： A61K49/0093 , A61K47/6903 , A61K47/6933 , A61K49/0032 , A61K49/0073 , B82Y5/00
摘要： The present invention relates to a nanogel comprising a polymer network of repetitive, crosslinked, ethylenically unsaturated monomers of Formula I: (X)m-(Y)n-(Z)o Formula I wherein X is a water-soluble monomer containing ionic or hydrogen bonding moieties; Y is a water-soluble macromonomer containing repetitive hydrophilic units bound to a polymerizeable ethylenically unsaturated group; Z is a multifunctional crosslinking monomer; m ranges from 50-90 mol %; n ranges from 2-30 mol %; and o range from 1-15 mol % and a method for preparing a nanogel comprising preparing a header composition of a mixture of monomers X, Y, and Z, and a first portion of initiators in water; preparing a reactor composition of a second portion initiators, surfactant, and water; bringing the reactor composition to the polymerization temperature; holding the reactor composition at the polymerization temperature, and adding the header composition to the reactor composition to form a nanogel of Formula I.
摘要翻译：本发明涉及纳米凝胶，其包含式I的重复，交联，烯键式不饱和单体的聚合物网络：<？在线公式描述=“在线式”末端=“铅”→（X）m- （Y）n-（Z）o式I <？in-line-formula description =“In-line Formulas”end =“tail”？>其中X是含有离子或氢键结构部分的水溶性单体; Y是含有与可聚合烯属不饱和基团结合的重复亲水单元的水溶性大分子单体; Z是多功能交联单体; m范围为50-90摩尔％; n范围为2-30mol％; 其范围为1-15mol％，制备纳米凝胶的方法包括制备单体X，Y和Z的混合物的头部组合物和在水中的第一部分引发剂; 制备第二部分引发剂，表面活性剂和水的反应器组合物; 使反应器组成达到聚合温度; 将反应器组合物保持在聚合温度，并将集管组合物加入到反应器组合物中以形成式I的纳米凝胶。

3. 发明授权

US07406797B2 Super high floating line 有权
标题翻译：超高浮线
公开(公告)号：US07406797B2
公开(公告)日：2008-08-05
申请号：US11213588
申请日：2005-08-26
申请人： John Harder , Marlin Roush , John Schultz , Timothy Moon
发明人： John Harder , Marlin Roush , John Schultz , Timothy Moon
IPC分类号： A01K91/00 , D02G3/00
CPC分类号： A01K91/12 , Y10T428/2927 , Y10T428/2929 , Y10T428/2933 , Y10T428/2967 , Y10T428/2969
摘要： Fly fishing lines and methods for manufacturing fly fishing lines entail the use of polymer microspheres within the fly line coating to produce lines with very low specific gravities. The fly lines have single or multiple coatings. In fly lines having multiple coatings, the inner coating includes polymer microspheres and the outer coating include either polymer microspheres or glass microspheres.
摘要翻译：飞钓线和用于制造飞钓线的方法需要在飞线涂层中使用聚合物微球以产生具有非常低比重的线。飞线具有单层或多层涂层。在具有多个涂层的飞线中，内涂层包括聚合物微球，外涂层包括聚合物微球体或玻璃微球体。

4. 发明申请

US20060293396A1 Amine polymer-modified nanoparticulate carriers 审中-公开
标题翻译：胺聚合物改性纳米颗粒载体
公开(公告)号：US20060293396A1
公开(公告)日：2006-12-28
申请号：US11165849
申请日：2005-06-24
申请人： Joseph Bringley , John Harder , Thomas Penner , Tiecheng Qiao , Ruizheng Wang
发明人： Joseph Bringley , John Harder , Thomas Penner , Tiecheng Qiao , Ruizheng Wang
IPC分类号： B01J13/00 , B32B5/16
CPC分类号： A61K9/146 , A61K9/5146 , A61K49/0032 , A61K49/0043 , A61K49/0076 , A61K49/0093 , B01J13/04 , C03C12/00 , C03C17/32 , Y10T428/2991 , Y10T428/2993 , Y10T428/2998
摘要： There are disclosed colloids containing polymer-modified core-shell particle carrier. The described colloids containing core-shell nanoparticulate carrier particles wherein the shell contains a polymer having amine functionalities. The described carrier particles are stable under physiological conditions. The carriers can be bioconjugated with biological, pharmaceutical or diagnostic components.
摘要翻译：公开了含有聚合物改性的核 - 壳粒子载体的胶体。所述胶体含有核 - 壳纳米颗粒载体颗粒，其中壳包含具有胺官能团的聚合物。所描述的载体颗粒在生理条件下是稳定的。载体可以与生物，药物或诊断成分生物共轭。

5. 发明申请

US20050192381A1 Amine polymer-modified nanoparticulate carriers 失效
标题翻译：胺聚合物改性纳米颗粒载体
公开(公告)号：US20050192381A1
公开(公告)日：2005-09-01
申请号：US11036814
申请日：2005-01-14
申请人： Joseph Bringley , Tiecheng Qiao , John Harder , Andrew Wunder , James Hewitt
发明人： Joseph Bringley , Tiecheng Qiao , John Harder , Andrew Wunder , James Hewitt
IPC分类号： B01J13/00 , B01J13/02 , B01J13/04 , C08F2/00
CPC分类号： B01J13/02 , B01J13/0008 , B01J13/0086 , B01J13/04 , Y10T428/2998
摘要： There are disclosed colloids containing polymer-modified core-shell particle carrier. The described colloids containing core-shell nanoparticulate carrier particles wherein the shell contains a polymer having amine functionalities. The described carrier particles are stable under physiological conditions. The carriers can be bioconjugated with biological, pharmaceutical or diagnostic components
摘要翻译：公开了含有聚合物改性的核 - 壳粒子载体的胶体。所述胶体含有核 - 壳纳米颗粒载体颗粒，其中壳包含具有胺官能团的聚合物。所描述的载体颗粒在生理条件下是稳定的。载体可以与生物，药物或诊断成分生物共轭

6. 发明授权

US4655448A Exercise apparatus 失效
标题翻译：运动器材
公开(公告)号：US4655448A
公开(公告)日：1987-04-07
申请号：US740729
申请日：1985-06-03
申请人： John Harder
发明人： John Harder
IPC分类号： A63B21/068 , A63B21/00
CPC分类号： A63B21/068
摘要： An exercise device of the body supporting type includes a generally H-shaped frame with collapsible legs at each end thereof, so that the frame can be elevated at the foot or head end; a board or backrest pivotally connected to the head end of the frame and extending towards the foot end of the frame; handles extending outwardly from the free end of the backrest for grasping by the user when in the prone position; and footrests for anchoring the feet of a user to the foot end of the frame. By grasping the handles and pressing against the footrests, the user can rotate the backrest around the head end of the frame to an inclined position in which the user is standing on the footrests.
摘要翻译：身体支撑型的运动装置包括在其每个端部具有可折叠的腿的大致H形的框架，使得框架可以在脚部或头部端部被升高; 枢转地连接到框架的头端并朝向框架的脚端延伸的板或靠背; 手柄从靠背的自由端向外延伸，用于当处于俯卧位时由使用者握住; 以及用于将使用者的脚固定到框架的脚端的搁脚板。通过握住把手并按压脚踏板，用户可以将围绕框架的头端的靠背旋转到使用者站在搁脚板上的倾斜位置。

7. 发明申请

US20060008751A1 Photographic material with improved development inhibitor releasers 失效
标题翻译：具有改善显影抑制剂释放剂的摄影材料
公开(公告)号：US20060008751A1
公开(公告)日：2006-01-12
申请号：US11211937
申请日：2005-08-25
申请人： Stephen Singer , Christopher Grote , Robert Stewart , John Harder , David Ross , Janet Younathan , Louis Friedrich
发明人： Stephen Singer , Christopher Grote , Robert Stewart , John Harder , David Ross , Janet Younathan , Louis Friedrich
IPC分类号： G03C1/46
CPC分类号： G03C7/30523 , G03C7/3029 , G03C7/30552 , G03C7/3212 , G03C7/344 , G03C2007/3034 , Y10S430/156 , Y10S430/158
摘要： This invention relates to a multilayer silver halide photographic element, generally processed with phenylenediamine based developer solutions, comprising a support bearing a cyan dye image-forming unit comprised of at least one red-sensitive silver halide emulsion layer having associated therewith at least one cyan dye-forming coupler, a magenta dye image-forming unit comprising at least one green-sensitive silver halide emulsion layer having associated therewith at least one magenta dye-forming coupler, and a yellow dye image-forming unit comprising at least one blue-sensitive silver halide emulsion layer having associated therewith at least one yellow dye-forming coupler, wherein at least one layer additionally contains a 2-substituted-5-amino-1-napthol DIR according to Formula (I): wherein: X is chosen from among hydrogen, halogen atoms, an alkyl group with 6 carbon atoms or less or a N-substituted carbamoyl group where the N substituent is either an alkyl group with 6 carbon atoms or less or an aryl group with 8 total carbon atoms or less; R is a carbonyl or sulfonyl group; and INH is an inhibitor of silver development. It has been found that such 2-substituted-5-amino-1-napthol based DIRs have improved properties and can provide a conventional silver halide photographic element with excellent image structure and color reproduction.
摘要翻译：本发明涉及通常用基于苯二胺的显影剂溶液加工的多层卤化银照相元件，其中包含载体，该载体带有青色染料影像形成单元，该单元由至少一种红色感光卤化银乳剂层组成，所述红色感光卤化银乳剂层具有至少一种青色染料包含至少一种具有与其相关的至少一种形成品红色染料的成色剂的至少一种感绿卤化银乳剂层的品红色染料影像形成单元和包含至少一种蓝色感光性银的黄色染料影像形成单元卤化物乳剂层，其与至少一种黄色染料形成成色剂相关联，其中至少一层另外含有根据式（I）的2-取代-5-氨基-1-萘酚DIR：其中：X选自氢卤素原子，6个碳原子或更少的烷基或N-取代的氨基甲酰基，其中N取代基是具有6个碳原子的烷基或更少或具有8个总碳原子或更少的芳基; R是羰基或磺酰基; 而INH是银发展的抑制剂。已经发现这种2-取代-5-氨基-1-萘酚基DIR具有改进的性能，并且可以提供具有优异的图像结构和色彩再现的常规卤化银照相元件。

8. 发明授权

US5924653A Traffic control system and method of controlling the movement of a mobile unit 失效
标题翻译：交通控制系统和控制移动单元移动的方法
公开(公告)号：US5924653A
公开(公告)日：1999-07-20
申请号：US809565
申请日：1997-06-06
申请人： Heine Ewi Pedersen , John Harder , Flemming Lohmann-Jensen
发明人： Heine Ewi Pedersen , John Harder , Flemming Lohmann-Jensen
IPC分类号： B61L3/12 , B61L27/00 , G08G1/09 , B61L1/00
CPC分类号： B61L3/121
摘要： A traffic control system for mobile units has a plurality of stationary, passive units having electronic store capacity and transmit and receive facilities. The store of the passive units contains an information code which is unique to the unit and is related to the position by a mobile unit, the stationary units supply their information code, enabling the mobile unit to calculate its position. The store of the stationary units, in addition to the information codes of the units, contains stored traffic messages which are supplied together with the information code upon interrogation from the mobile unit. The movement from the mobile unit can be adjusted according to the traffic information received.
摘要翻译： PCT No.PCT / DK95 / 00382 Sec。 371日期：1997年6月6日 102（e）日期1997年6月6日PCT 1995年9月25日PCT公布。出版物WO96 / 09199 日期1996年3月28日移动单元的交通控制系统具有多个具有电子商店容量的固定，被动单元和发送和接收设施。无源单元的存储包含该单元唯一的信息代码，并且与移动单元的位置相关，固定单元提供其信息代码，使得移动单元能够计算其位置。除了单元的信息代码之外，固定单元的存储包含从移动单元询问时与信息代码一起提供的存储的交通消息。来自移动单元的移动可以根据接收的交通信息进行调整。

9. 发明授权

US07563485B2 Method of manufacturing a super high floating line 有权
标题翻译：制造超高浮线的方法
公开(公告)号：US07563485B2
公开(公告)日：2009-07-21
申请号：US11387621
申请日：2006-03-23
申请人： John Harder , Marlin Roush , John Schultz , Timothy Moon
发明人： John Harder , Marlin Roush , John Schultz , Timothy Moon
IPC分类号： B05D5/00 , B05D7/02 , B05D7/24 , A01K91/00
CPC分类号： A01K91/12 , Y10T428/2927 , Y10T428/2929 , Y10T428/2933 , Y10T428/2967 , Y10T428/2969
摘要： Methods of manufacturing fly fishing lines with very low specific gravities entail adding polymer microspheres to a base coating and coating a core with the base coating containing the added polymer microspheres. To manufacture fly lines having multiple coatings, a second coating, which may contain polymer or glass microspheres, is disposed around a first coating that contains polymer microspheres.
摘要翻译：制造具有非常低比重的飞钓线的方法需要将聚合物微球加入到基底涂层中，并用含有添加的聚合物微球体的基底涂层涂覆芯。为了制造具有多个涂层的飞线，可以包含聚合物或玻璃微球的第二涂层围绕包含聚合物微球的第一涂层设置。

10. 发明申请

US20060172077A1 Method of manufacturing a super high floating line 有权
标题翻译：制造超高浮线的方法
公开(公告)号：US20060172077A1
公开(公告)日：2006-08-03
申请号：US11387621
申请日：2006-03-23
申请人： John Harder , Marlin Roush , John Schultz , Timothy Moon
发明人： John Harder , Marlin Roush , John Schultz , Timothy Moon
IPC分类号： B05D1/18
CPC分类号： A01K91/12 , Y10T428/2927 , Y10T428/2929 , Y10T428/2933 , Y10T428/2967 , Y10T428/2969
摘要： Fly fishing lines and methods for manufacturing fly fishing lines entail the use of polymer microspheres within the fly line coating to produce lines with very low specific gravities. The fly lines have single or multiple coatings. In fly lines having multiple coatings, the inner coating includes polymer microspheres and the outer coating include either polymer microspheres or glass microspheres.
摘要翻译：飞钓线和用于制造飞钓线的方法需要在飞线涂层中使用聚合物微球以产生具有非常低比重的线。飞线具有单层或多层涂层。在具有多个涂层的飞线中，内涂层包括聚合物微球，外涂层包括聚合物微球体或玻璃微球体。

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