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1. 发明授权

US08920402B2 Thrombectomy and soft debris removal device 有权
标题翻译：血栓切除术和软切除装置
公开(公告)号：US08920402B2
公开(公告)日：2014-12-30
申请号：US11871908
申请日：2007-10-12
申请人： John E. Nash , Greg Walters , Dennis M. Sauro , Mark Eberhardt , William T. Fisher , Douglas G. Evans
发明人： John E. Nash , Greg Walters , Dennis M. Sauro , Mark Eberhardt , William T. Fisher , Douglas G. Evans
IPC分类号： A61M25/00 , A61B17/3207
CPC分类号： A61B17/320758 , A61B17/320783 , A61B2017/00685 , A61B2017/320733 , A61B2017/320741 , A61B2017/320766 , A61B2217/005
摘要： A device suitable for removing material from a living being is provided, featuring at least an aspiration pump, powered by a motor. The aspiration pump and any optional infusate pump preferably feature a helical pumping mechanism, and operate at a high rate of rotation, thereby ensuring adequate pumping performance and flexibility. The helical pumping mechanism may be a helical coiled wire about a central core tube. The helical coil wire, whether together with, or independent of, the core tube, may be rotated to cause a pumping action. Additionally, a narrow crossing profile is maintained, ensuring that the device may reach more tortuous regions of the vasculature. In one embodiment, the system comprises a wire-guided mono-rail catheter with a working head mounted on a flexible portion of the catheter that can laterally displace away from the guide wire to facilitate thrombus removal. The working head may be operated to separate and move away from the guide wire to come within a closer proximity of the obstructive material to more effectively remove it from the vessel.
摘要翻译：提供一种适用于从活体中去除材料的装置，其特征在于至少一个由马达驱动的抽吸泵。抽吸泵和任何可选的输注泵优选地具有螺旋泵送机构，并且以高转速进行操作，从而确保了足够的泵送性能和灵活性。螺旋泵送机构可以是围绕中心芯管的螺旋卷绕的线。螺旋线圈线，无论是与芯管一起，还是独立于芯管，可以旋转以引起泵送动作。另外，保持狭窄的横截面，确保装置可能达到脉管系统的更曲折的区域。在一个实施例中，系统包括导线单轨导管，其具有安装在导管的柔性部分上的工作头，所述工作头能横向移位远离引导线以促进血栓移除。工作头可以被操作以分离并远离引导线进入更靠近阻塞物质的位置，以更有效地将其从容器中移出。

2. 发明授权

US07976528B2 Thrombectomy and soft debris removal device 有权
标题翻译：血栓切除术和软切除装置
公开(公告)号：US07976528B2
公开(公告)日：2011-07-12
申请号：US12705332
申请日：2010-02-12
申请人： John E. Nash , Greg Walters , Dennis M. Sauro , Mark Eberhart , William T. Fisher , Douglas G. Evans
发明人： John E. Nash , Greg Walters , Dennis M. Sauro , Mark Eberhart , William T. Fisher , Douglas G. Evans
IPC分类号： A61M31/00 , A61M25/00
CPC分类号： A61B17/32037 , A61B17/320783 , A61B2017/00685 , A61B2017/22039 , A61B2017/22067 , A61B2017/22084 , A61M1/0058 , A61M1/0066 , A61M1/101 , A61M25/0068 , A61M25/0069 , A61M25/007 , A61M25/0082 , A61M25/10 , A61M2025/0177 , A61M2025/0183 , A61M2025/1052
摘要： A device suitable for removing material from a living being is provided, featuring an infusate pump, and an aspiration pump, both powered by a motor. The aspiration pump and infusate pump preferably feature a helical pumping mechanism, and operate at a high rate of rotation, thereby ensuring adequate pumping performance and flexibility. Additionally, a narrow crossing profile is maintained, ensuring that the device may reach more tortuous regions of the vasculature. In one embodiment, the system comprises a wire-guided mono-rail catheter with a working head mounted on a flexible portion of the catheter that can laterally displace away from the guide wire to facilitate thrombus removal. The working head may be operated to separate and move away from the guide wire to come within a closer proximity of the obstructive material to more effectively remove it from the vessel.
摘要翻译：提供了一种适用于从活体中去除材料的装置，其特征在于具有输注泵和吸引泵，两者都由马达驱动。抽吸泵和输注泵优选地具有螺旋泵送机构，并且以高转速进行操作，从而确保足够的泵送性能和柔性。另外，保持狭窄的横截面，确保装置可能达到脉管系统的更曲折的区域。在一个实施例中，系统包括导线单轨导管，其具有安装在导管的柔性部分上的工作头，所述工作头可横向移位远离导丝以促进血栓移除。工作头可以被操作以分离并远离引导线进入更靠近阻塞物质的位置，以更有效地将其从容器中移出。

3. 发明申请

US20100145259A1 THROMBECTOMY AND SOFT DEBRIS REMOVAL DEVICE 有权
标题翻译：镜像和软件去除设备
公开(公告)号：US20100145259A1
公开(公告)日：2010-06-10
申请号：US12705332
申请日：2010-02-12
申请人： John E. Nash , Greg Walters , Dennis M. Sauro , Mark Eberhart , William T. Fisher , Douglas G. Evans
发明人： John E. Nash , Greg Walters , Dennis M. Sauro , Mark Eberhart , William T. Fisher , Douglas G. Evans
IPC分类号： A61B17/22
CPC分类号： A61B17/32037 , A61B17/320783 , A61B2017/00685 , A61B2017/22039 , A61B2017/22067 , A61B2017/22084 , A61M1/0058 , A61M1/0066 , A61M1/101 , A61M25/0068 , A61M25/0069 , A61M25/007 , A61M25/0082 , A61M25/10 , A61M2025/0177 , A61M2025/0183 , A61M2025/1052
摘要： A device suitable for removing material from a living being is provided, featuring an infusate pump, and an aspiration pump, both powered by a motor. The aspiration pump and infusate pump preferably feature a helical pumping mechanism, and operate at a high rate of rotation, thereby ensuring adequate pumping performance and flexibility. Additionally, a narrow crossing profile is maintained, ensuring that the device may reach more tortuous regions of the vasculature. In one embodiment, the system comprises a wire-guided mono-rail catheter with a working head mounted on a flexible portion of the catheter that can laterally displace away from the guide wire to facilitate thrombus removal. The working head may be operated to separate and move away from the guide wire to come within a closer proximity of the obstructive material to more effectively remove it from the vessel.
摘要翻译：提供了一种适用于从活体中去除材料的装置，其特征在于具有输注泵和吸引泵，两者都由马达驱动。抽吸泵和输注泵优选地具有螺旋泵送机构，并且以高转速进行操作，从而确保足够的泵送性能和柔性。另外，保持狭窄的横截面，确保装置可能达到脉管系统的更曲折的区域。在一个实施例中，系统包括导线单轨导管，其具有安装在导管的柔性部分上的工作头，所述工作头可横向移位远离导丝以促进血栓移除。工作头可以被操作以分离并远离引导线进入更靠近阻塞物质的位置，以更有效地将其从容器中移出。

4. 发明授权

US07666161B2 Thrombectomy and soft debris removal device 有权
标题翻译：血栓切除术和软切除装置
公开(公告)号：US07666161B2
公开(公告)日：2010-02-23
申请号：US11751443
申请日：2007-05-21
申请人： John E. Nash , Greg Walters , Dennis M. Sauro , Mark Eberhart , William T. Fisher , Douglas G. Evans
发明人： John E. Nash , Greg Walters , Dennis M. Sauro , Mark Eberhart , William T. Fisher , Douglas G. Evans
IPC分类号： A61B17/20 , A61B17/22 , A61M25/00
CPC分类号： A61B17/32037 , A61B17/320783 , A61B2017/00685 , A61B2017/22039 , A61B2017/22067 , A61B2017/22084 , A61M1/0058 , A61M1/0066 , A61M1/101 , A61M25/0068 , A61M25/0069 , A61M25/007 , A61M25/0082 , A61M25/10 , A61M2025/0177 , A61M2025/0183 , A61M2025/1052
摘要： A device suitable for removing material from a living being is provided, featuring an infusate pump, and an aspiration pump, both powered by a motor. The aspiration pump and infusate pump preferably feature a helical pumping mechanism, and operate at a high rate of rotation, thereby ensuring adequate pumping performance and flexibility. Additionally, a narrow crossing profile is maintained, ensuring that the device may reach more tortuous regions of the vasculature. In one embodiment, the system comprises a wire-guided mono-rail catheter with a working head mounted on a flexible portion of the catheter that can laterally displace away from the guide wire to facilitate thrombus removal. The working head may be operated to separate and move away from the guide wire to come within a closer proximity of the obstructive material to more effectively remove it from the vessel.
摘要翻译：提供了一种适用于从活体中去除材料的装置，其特征在于具有输注泵和吸引泵，两者都由马达驱动。抽吸泵和输注泵优选地具有螺旋泵送机构，并且以高转速进行操作，从而确保足够的泵送性能和柔性。另外，保持狭窄的横截面，确保装置可能达到脉管系统的更曲折的区域。在一个实施例中，系统包括导线单轨导管，其具有安装在导管的柔性部分上的工作头，所述工作头可横向移位远离导丝以促进血栓移除。工作头可以被操作以分离并远离引导线进入更靠近阻塞物质的位置，以更有效地将其从容器中移出。

5. 发明授权

US07959608B2 Thrombectomy and soft debris removal device 有权
标题翻译：血栓切除术和软切除装置
公开(公告)号：US07959608B2
公开(公告)日：2011-06-14
申请号：US10832830
申请日：2004-04-27
申请人： John E. Nash , Greg Walters , Dennis M. Sauro , Mark Eberhart , William T. Fisher
发明人： John E. Nash , Greg Walters , Dennis M. Sauro , Mark Eberhart , William T. Fisher
IPC分类号： A61M37/00 , A61M1/00
CPC分类号： A61B17/32037 , A61B17/320783 , A61B2017/00685 , A61B2017/22039 , A61B2017/22067 , A61B2017/22084 , A61M1/0058 , A61M1/0066 , A61M1/101 , A61M25/0068 , A61M25/0069 , A61M25/007 , A61M25/0082 , A61M25/10 , A61M2025/0177 , A61M2025/0183 , A61M2025/1052
摘要： A device suitable for removing material from a living being is provided, featuring an infusate pump, and an aspiration pump, both powered by a motor. The aspiration pump and infusate pump preferably feature a helical pumping mechanism, and operate at a high rate of rotation, thereby ensuring adequate pumping performance and flexibility. Additionally, a narrow crossing profile is maintained, ensuring that the device may reach more tortuous regions of the vasculature.
摘要翻译：提供了一种适用于从活体中去除材料的装置，其特征在于具有输注泵和吸引泵，两者都由马达驱动。抽吸泵和输注泵优选地具有螺旋泵送机构，并且以高转速进行操作，从而确保足够的泵送性能和柔性。另外，保持狭窄的横截面，确保装置可能达到脉管系统的更曲折的区域。

6. 发明授权

US08267871B2 Guidewire mounted balloon modulation device and methods of use 有权
标题翻译：导丝安装球囊调制装置及使用方法
公开(公告)号：US08267871B2
公开(公告)日：2012-09-18
申请号：US10840727
申请日：2004-05-06
申请人： Mark Eberhardt , William T. Fisher , John E. Nash , Dennis M. Sauro
发明人： Mark Eberhardt , William T. Fisher , John E. Nash , Dennis M. Sauro
IPC分类号： A61B5/00
CPC分类号： A61M25/10182 , A61M25/10184 , A61M25/10185
摘要： An apparatus for modulating the pressure of a fluid such as a gas within the expandable portion of a guide wire catheter. A preferred embodiment apparatus features a mechanism for controllably gripping and releasing the open, proximal end of a tubular guide wire, a mechanism for introducing a fluid to a desired pressure and volume into the expandable portion of the tubular guide wire through the open end, and, while maintaining the pressure and volume of fluid in the tubular guide wire, a mechanism for introducing a sealing member into the open end of the tubular guide wire to seal the fluid in the tubular guide wire. In a particularly preferred embodiment, the apparatus also features a deflation tool for piercing the seal and letting the fluid out. Using this apparatus, the tubular guide wire can be re-sealed and re-opened as necessary.
摘要翻译：一种用于调节导丝导管内的可膨胀部分内的流体例如气体的压力的装置。优选的实施例装置具有用于可控地夹紧和释放管状导丝的开口近端的机构，用于将流体通过开口端引导到管状导丝的可膨胀部分中的期望压力和体积的机构，以及同时保持管状导丝中的流体的压力和体积，用于将密封构件引入管状导丝的开口端以将管状导丝中的流体密封的机构。在特别优选的实施例中，该装置还具有用于刺穿密封件并使流体流出的放气工具。使用这种装置，可以根据需要重新密封和重新打开管状导丝。

7. 发明授权

US07004914B2 Crimp and cut tool for sealing and unsealing guide wires and tubular instruments 失效
标题翻译：压接和切割工具，用于密封和开封导丝和管状仪器
公开(公告)号：US07004914B2
公开(公告)日：2006-02-28
申请号：US10264001
申请日：2002-10-03
申请人： Mark Eberhart , William T. Fisher , John E. Nash , Dennis M. Sauro
发明人： Mark Eberhart , William T. Fisher , John E. Nash , Dennis M. Sauro
IPC分类号： A61B5/00 , A61M25/00
CPC分类号： A61M25/10184 , A61M25/09033 , A61M25/10182 , A61M25/10185 , A61M25/104 , A61M2025/105
摘要： An apparatus for modulating the pressure of a fluid such as a gas within the expandable portion of a guide wire catheter. In one embodiment, the pressure and volume of fluid in the tubular guide wire is maintained by utilizing an apparatus to crimp the end of the tubular guide wire, effectively sealing the inside bore of the tubular guide wire. Here, a deflation tool might be employed to sever the crimp from the rest of the tubular guide wire, unsealing the bore of the tubular guide wire. Using this apparatus, the tubular guide wire can be re-sealed and re-opened as necessary.
摘要翻译：一种用于调节诸如导丝导管的可扩张部分内的气体的流体的压力的装置。在一个实施例中，管状导丝中的流体的压力和体积通过使用压接管状导丝的端部的装置来保持，有效地密封管状导丝的内孔。这里，可以采用放气工具来切断与管状导丝的其余部分的卷曲，从而开封管状导丝线的孔。使用这种装置，可以根据需要重新密封和重新打开管状导丝。

8. 发明授权

US07226425B2 Crimp and cut tool for sealing and unsealing guide wires and tubular instruments 有权
标题翻译：压接和切割工具，用于密封和开封导丝和管状仪器
公开(公告)号：US07226425B2
公开(公告)日：2007-06-05
申请号：US11232178
申请日：2005-09-20
申请人： Mark Eberhart , William T. Fisher , John E. Nash , Dennis M. Sauro
发明人： Mark Eberhart , William T. Fisher , John E. Nash , Dennis M. Sauro
IPC分类号： A61B5/00 , A61M25/00
CPC分类号： A61M25/10184 , A61M25/09033 , A61M25/10182 , A61M25/10185 , A61M25/104 , A61M2025/105
摘要： An apparatus for modulating the pressure of a fluid such as a gas within the expandable portion of a guide wire catheter. The apparatus features a means for controllably gripping and releasing the open, proximal end of a tubular guide wire, means for introducing a fluid to a desired pressure and volume into the expandable portion of the tubular guide wire through the open end, and, while maintaining the pressure and volume of fluid in the tubular guide wire, a means for sealing the open end of said tubular guide wire to seal the fluid in the tubular guide wire. In a preferred embodiment, the apparatus also features a deflation tool for re-opening the sealed tubular guide wire and letting the fluid out. In a particularly preferred embodiment, the pressure and volume of fluid in the tubular guide wire is maintained by utilizing an apparatus to crimp the end of the tubular guide wire, effectively sealing the inside bore of the tubular guide wire. Here, a deflation tool might comprise a means of severing the crimp from the rest of the tubular guide wire, unsealing the bore of the tubular guide wire. Preferably, the crossing profile of the crimped tubular guide wire is no greater than what it was prior to crimping. Using this apparatus, the tubular guide wire can be re-sealed and re-opened as necessary.
摘要翻译：一种用于调节诸如导丝导管的可扩张部分内的气体的流体的压力的装置。该装置具有用于可控地夹紧和释放管状导丝的开口近端的装置，用于将流体通过开口端引入到管状导丝的可膨胀部分中的期望压力和体积的装置，以及在保持管状导丝中的流体的压力和体积，用于密封所述管状导丝的开口端以密封管状导丝中的流体的装置。在优选实施例中，该装置还具有用于重新打开密封的管状导丝并使流体流出的放气工具。在特别优选的实施例中，管状导丝中的流体的压力和体积通过使用压接管状导丝的端部的装置来保持，有效地密封管状导丝的内孔。这里，放气工具可以包括切断来自管状导丝的其余部分的卷曲的装置，从而开封管状导丝的孔。优选地，卷曲的管状导丝的交叉轮廓不大于卷曲之前的交叉轮廓。使用这种装置，可以根据需要重新密封和重新打开管状导丝。

9. 发明授权

US07771370B2 Guide-wire mounted balloon modulation device and methods of use 有权
标题翻译：导丝安装球囊调制装置及使用方法
公开(公告)号：US07771370B2
公开(公告)日：2010-08-10
申请号：US11439525
申请日：2006-05-22
申请人： Mark Eberhart , William T. Fisher , John E. Nash , Dennis M. Sauro
发明人： Mark Eberhart , William T. Fisher , John E. Nash , Dennis M. Sauro
IPC分类号： A61B5/00 , A61M29/00
CPC分类号： A61M25/10185 , A61M25/0606 , A61M25/09041 , A61M25/10182 , A61M25/104 , A61M39/06 , A61M2210/125
摘要： An apparatus for modulating the pressure of a fluid such as a gas within the expandable portion of a guide wire catheter. A preferred embodiment apparatus features a means for controllably gripping and releasing the open, proximal end of a tubular guide wire, means for introducing a fluid to a desired pressure and volume into the expandable portion of the tubular guide wire through the open end, and, while maintaining the pressure and volume of fluid in the tubular guide wire, a means for introducing a sealing member into the open end of said tubular guide wire to seal the fluid in the tubular guide wire. In a particularly preferred embodiment, the apparatus also features a deflation tool for piercing the seal and letting the fluid out. Using this apparatus, the tubular guide wire can be re-sealed and re-opened as necessary.
摘要翻译：一种用于调节诸如导丝导管的可扩张部分内的气体的流体的压力的装置。优选的实施例装置具有用于可控制地夹紧和释放管状导丝的开口近端的装置，用于将流体引导到通过开口端的管状导丝的可膨胀部分中的期望压力和体积的装置，同时保持管状导丝中的流体的压力和体积，用于将密封构件引入所述管状导丝的开口端以将管状导丝中的流体密封的装置。在特别优选的实施例中，该装置还具有用于刺穿密封件并使流体流出的放气工具。使用这种装置，可以根据需要重新密封和重新打开管状导丝。

10. 发明授权

US06902535B2 Guide-wire mounted balloon modulation device and methods of use 有权
标题翻译：导丝安装球囊调制装置及使用方法
公开(公告)号：US06902535B2
公开(公告)日：2005-06-07
申请号：US10227996
申请日：2002-08-26
申请人： Mark Eberhart , William T. Fisher , John E. Nash , Dennis M. Sauro
发明人： Mark Eberhart , William T. Fisher , John E. Nash , Dennis M. Sauro
IPC分类号： A61F2/958 , A61B5/00 , A61M25/00
CPC分类号： A61M25/10185 , A61M25/0606 , A61M25/09041 , A61M25/10182 , A61M25/104 , A61M39/06 , A61M2210/125
摘要： An apparatus for modulating the pressure of a fluid such as a gas within the expandable portion of a guide wire catheter. A preferred embodiment apparatus features a mechanism for controllably gripping and releasing the open, proximal end of a tubular guide wire, a mechanism for introducing a fluid to a desired pressure and volume into the expandable portion of the tubular guide wire through the open end, and, while maintaining the pressure and volume of fluid in the tubular guide wire, a mechanism for introducing a sealing member into the open end of the tubular guide wire to seal the fluid in the tubular guide wire. In a particularly preferred embodiment, the apparatus also features a deflation tool for piercing the seal and letting the fluid out. Using this apparatus, the tubular guide wire can be re-sealed and re-opened as necessary.
摘要翻译：一种用于调节导丝导管内的可膨胀部分内的流体例如气体的压力的装置。优选的实施例装置具有用于可控地夹紧和释放管状导丝的开口近端的机构，用于将流体通过开口端引导到管状导丝的可膨胀部分中的期望压力和体积的机构，以及同时保持管状导丝中的流体的压力和体积，用于将密封构件引入管状导丝的开口端以将管状导丝中的流体密封的机构。在特别优选的实施例中，该装置还具有用于刺穿密封件并使流体流出的放气工具。使用这种装置，可以根据需要重新密封和重新打开管状导丝。

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