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    • 4. 发明授权
    • System and method for a non-invasive blood pressure measurement
    • 非侵入性血压测量的系统和方法
    • US08308647B2
    • 2012-11-13
    • US12415575
    • 2009-03-31
    • Sai KolluriLawrence HershRichard Medero
    • Sai KolluriLawrence HershRichard Medero
    • A61B5/02
    • A61B5/022A61B5/02225A61B5/0225
    • A method of measuring blood pressure of a patient is provided. The method comprises inflating a blood pressure cuff to a user selectable target pressure and subsequently further inflating or deflating the blood pressure cuff in a stepwise manner by a predetermined pressure amount. At each pressure step in a first sequence of alternate steps of cuff pressure variation, the occurrence of at least two successive oscillometric pulses with matching pulse amplitude and other possible matching criteria is identified. The blood pressure cuff is inflated following the identification. Further a single oscillometric pulse is obtained at each pressure step in a second sequence of alternate steps of cuff pressure variation. The pattern of inflating, obtaining two matching oscillometric pulses, inflating, and obtaining a single oscillometric pulse is repeated until sufficient oscillometric envelope information is obtained for determining one or more blood pressure parameters of the patient.
    • 提供了一种测量患者血压的方法。 该方法包括将血压套管充气至使用者可选择的目标压力,随后进一步使血压袖带以预定的压力量逐步膨胀或放气。 在袖带压力变化的替代步骤的第一序列中的每个压力步骤,识别具有匹配脉冲幅度和其他可能的匹配标准的至少两个连续示波脉冲的出现。 识别后血压袖带膨胀。 此外,在袖带压力变化的另一步骤的第二序列中的每个压力步骤处获得单个示波脉冲。 重复充气,获得两个匹配的示波脉冲,充气和获得单个示波脉冲的模式,直到获得用于确定患者的一个或多个血压参数的足够的示波包络信息。
    • 5. 发明申请
    • SYSTEM AND METHOD FOR A NON-INVASIVE BLOOD PRESSURE MEASUREMENT
    • 非入血血压测量的系统和方法
    • US20100249614A1
    • 2010-09-30
    • US12415575
    • 2009-03-31
    • Sai KolluriLawrence HershRichard Medero
    • Sai KolluriLawrence HershRichard Medero
    • A61B5/022
    • A61B5/022A61B5/02225A61B5/0225
    • A method of measuring blood pressure of a patient is provided. The method comprises inflating a blood pressure cuff to a user selectable target pressure and subsequently further inflating or deflating the blood pressure cuff in a stepwise manner by a predetermined pressure amount. At each pressure step in a first sequence of alternate steps of cuff pressure variation, the occurrence of at least two successive oscillometric pulses with matching pulse amplitude and other possible matching criteria is identified. The blood pressure cuff is inflated following the identification. Further a single oscillometric pulse is obtained at each pressure step in a second sequence of alternate steps of cuff pressure variation. The pattern of inflating, obtaining two matching oscillometric pulses, inflating, and obtaining a single oscillometric pulse is repeated until sufficient oscillometric envelope information is obtained for determining one or more blood pressure parameters of the patient.
    • 提供了一种测量患者血压的方法。 该方法包括将血压套管充气至使用者可选择的目标压力,随后进一步使血压袖带以预定的压力量逐步膨胀或放气。 在袖带压力变化的替代步骤的第一序列中的每个压力步骤,识别具有匹配脉冲幅度和其他可能的匹配标准的至少两个连续示波脉冲的出现。 识别后血压袖带膨胀。 此外,在袖带压力变化的另一步骤的第二序列中的每个压力步骤处获得单个示波脉冲。 重复充气,获得两个匹配的示波脉冲,充气和获得单个示波脉冲的模式,直到获得用于确定患者的一个或多个血压参数的足够的示波包络信息。
    • 8. 发明申请
    • Method and apparatus for determining extreme blood pressure values
    • 用于确定极端血压值的方法和装置
    • US20050261597A1
    • 2005-11-24
    • US10847934
    • 2004-05-18
    • Sai KolluriLawrence HershBruce FriedmanRichard Medero
    • Sai KolluriLawrence HershBruce FriedmanRichard Medero
    • A61B5/02A61B5/0225A61B5/04A61B5/0456
    • A61B5/02225A61B5/0225A61B5/0456
    • In a method and apparatus for measuring extreme blood pressure values during a single non-invasive blood measurement, the time intervals between sequential heartbeats are measured for a series of heartbeats in an oscillometric blood pressure measurement time period. Oscillometric blood pressure measurement data for the heartbeats of the series is obtained and associated with the heartbeat time intervals. An average time interval between heartbeats is also determined. A first data bin may be defined for blood pressure data associated with time intervals that are longer as compared to the average time interval. A second data bin is defined for blood pressure data with time intervals that are shorter as compared to the average time interval. The measured oscillometric blood pressure data is sorted into the data bins in accordance with the associated time intervals. The data in the first data bin is used to derive a high systolic blood pressure value and a low diastolic blood pressure value. The data in the second bin is used to derive a low systolic blood pressure value and a high diastolic blood pressure value. A typical blood pressure value may also be determined.
    • 在用于在单次非侵入性血液测量期间测量极端血压值的方法和装置中,测量在示波血压测量时间段内的一系列心跳的连续心跳之间的时间间隔。 获得该系列心跳的示波血压测量数据,并与心跳时间间隔相关联。 心跳之间的平均时间间隔也被确定。 可以为与与平均时间间隔相比较长的时间间隔相关联的血压数据定义第一数据箱。 第二个数据仓被定义为与平均时间间隔相比时间间隔更短的血压数据。 测量的示波血压数据根据相关联的时间间隔被分类到数据箱中。 第一数据箱中的数据用于导出高收缩压值和低舒张压值。 第二个仓中的数据用于导出低收缩压值和高舒张压值。 也可以确定典型的血压值。
    • 9. 发明授权
    • Continuous, non-invasive technique for measuring blood pressure using impedance plethysmography
    • 使用阻抗体积描记法测量血压的连续,非侵入性技术
    • US06648828B2
    • 2003-11-18
    • US09683916
    • 2002-03-01
    • Bruce A. FriedmanRichard MederoLawrence T. HershSai Kolluri
    • Bruce A. FriedmanRichard MederoLawrence T. HershSai Kolluri
    • A61B502
    • A61B5/0285A61B5/021A61B5/02125A61B5/0295
    • Blood pressure is measured using the pulse transit time required for the blood volume pulse to propagate between two locations in an animal. Impedance plethysmography is employed to detect when the blood volume pulse occurs at one location. The plethysmograph may detect thoracic impedance to determine when the aortic heart valve opens or it may detect impedance at one location on a limb of the animal. Occurrence of the blood volume pulse at another location can be determined by impedance plethysmography or another technique, such as pulse oximetry. The calculation of cardiac stroke volume can be employed to compensate the derivation of the blood pressure for effects due to blood vessel compliance. A nonblood pressure monitor may periodically provide a reference blood pressure measurement that is used calibrate derivation of the blood pressure based on the pulse transit time.
    • 使用血液体积脉冲在动物的两个位置之间传播所需的脉搏传播时间来测量血压。 采用阻抗体积描记法检测血液体积脉搏何时出现在一个位置。 体积描记器可以检测胸部阻抗以确定主动脉瓣心脏瓣膜何时打开,或者可以在动物肢体的一个位置处检测阻抗。 可以通过阻抗体积描记法或其他技术(例如脉搏血氧测定法)来确定另一位置处的血容量脉冲的发生。 心脏搏动量的计算可用于补偿由于血管依从性引起的血压的推导。 非血压监视器可以周期性地提供参考血压测量,其用于基于脉冲传播时间来校准血压的推导。
    • 10. 发明授权
    • NIBP playback system
    • NIBP播放系统
    • US5800359A
    • 1998-09-01
    • US445273
    • 1995-05-19
    • Richard MederoJohn W. Booth
    • Richard MederoJohn W. Booth
    • A61B5/0215A61B5/022A61B5/0255A61B5/02
    • A61B5/02225A61B5/02156A61B5/022A61B5/0255
    • A data playback device which records, stores, and plays back actual patient oscillometric blood pressure data to create a more realistic NIBP simulation for testing of an NIBP monitor. The system is made up of two units, a computer and a converter. The converter has a Universal Asynchronous Receiver/Transmitter (UART) connected to the computer and 16-bit D/A and A/D converters connected to the input and output, respectively, of a blood pressure monitor. The A/D converter senses cuff pressure and sends the signal to the computer. The computer then calculates the pressure pulse data from the stored patient data and sends it to the monitor via the D/A converter, where the pressure pulse data is converted to a voltage and electronically summed with the pressure transducer signal output by the blood pressure monitor under test. Typically, the playback system reads the current cuff pressure in the blood pressure monitor and "plays back" the oscillation complex from the data file whose average pressure is closest to the current cuff pressure. The oscillation complex is scaled to the proper amplitude using linear interpolation before it is summed into the cuff pressure channel. This process is repeated for each pressure level during the oscillometric blood pressure determination. During testing, the blood pressure monitor sees an oscillation envelope and oscillation complex shapes similar to the original data from a real patient.
    • 数据回放装置,其记录,存储和重放实际的患者示波血压数据,以创建用于测试NIBP监测器的更现实的NIBP模拟。 该系统由两个单元组成,一个是计算机和一个转换器。 该转换器具有连接到计算机的通用异步收发器(UART)和分别连接到血压计输入和输出的16位D / A和A / D转换器。 A / D转换器感测袖带压力,并将信号发送到计算机。 然后,计算机从存储的患者数据计算压力脉冲数据,并通过D / A转换器将其发送到监视器,其中压力脉冲数据被转换成电压,并与由血压计输出的压力传感器信号电子相加 被测试。 通常,回放系统读取血压监视器中的当前袖带压力并从平均压力最接近当前袖带压力的数据文件“回放”振荡复合体。 使用线性内插法将振荡复合体缩放到适当的幅度,然后将其合并到袖带压力通道中。 在示波器血压测定期间,针对每个压力水平重复该过程。 在测试期间,血压监测仪看到与真实患者的原始数据相似的振荡包络和振荡复杂形状。