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1. 发明申请

US20110033458A1 COMBINATIONS COMPRISING EPOTHILONES AND PHARMACEUTICAL USES THEREOF 审中-公开
标题翻译：包含EPOTHILONES及其药物用途的组合
公开(公告)号：US20110033458A1
公开(公告)日：2011-02-10
申请号：US12908533
申请日：2010-10-20
申请人： John Arthur Hohneker , Julie Ann Miller , John David Rothermel , Markus Wartmann
发明人： John Arthur Hohneker , Julie Ann Miller , John David Rothermel , Markus Wartmann
IPC分类号： A61K39/395 , A61K31/427 , A61P35/00
CPC分类号： C07K16/3015 , A61K31/426 , A61K31/427 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07D417/06 , A61K2300/00
摘要： The invention relates to a pharmaceutical combination which comprises (a) a HER-1 or a HER-2 antibody or (b) at least one antineoplastic agent selected from the group consisting of aromatase inhibitors, antiestrogens, topoisomerase I inhibitors, topoisomerase II inhibitors, microtubule active agents, protein kinase C inhibitors, anti-angiogenic compounds, gonadorelin agonists, anti-androgens, histone deacetylase inhibitors and S-adenosylmethionine decarboxylase inhibitors; and (c) an epothilone derivative of formula I and optionally at least one pharmaceutically acceptable carrier for simultaneous, separate or sequential use, in particular, for the treatment of a proliferative disease, especially a solid tumor disease; a pharmaceutical composition comprising such a combination; the use of such a combination for the preparation of a medicament for the treatment of a proliferative disease; a commercial package or product comprising such a combination as a combined preparation for simultaneous, separate or sequential use; and to a method of treatment of a warm-blooded animal, especially a human.
摘要翻译：本发明涉及药物组合，其包含（a）HER-1或HER-2抗体或（b）至少一种抗肿瘤剂，其选自芳香酶抑制剂，抗雌激素，拓扑异构酶I抑制剂，拓扑异构酶II抑制剂，微管活性剂，蛋白激酶C抑制剂，抗血管生成化合物，促性腺激素激动剂，抗雄激素，组蛋白脱乙酰酶抑制剂和S-腺苷甲硫氨酸脱羧酶抑制剂; 和（c）式I的埃坡霉素衍生物和任选的至少一种用于同时，分别或顺序使用的药学上可接受的载体，特别是用于治疗增殖性疾病，特别是实体肿瘤疾病; 包含这种组合的药物组合物; 使用这种组合来制备用于治疗增殖性疾病的药物; 包括作为用于同时，分开或顺序使用的组合制剂的组合的商业包装或产品; 以及治疗温血动物，特别是人的方法。

2. 发明申请

US20100167782A1 TRANSACTION CONTROL SYSTEM INCLUDING PORTABLE DATA TERMINAL AND MOBILE CUSTOMER SERVICE STATION 有权
标题翻译：包括便携式数据终端和移动客户服务站的交易控制系统
公开(公告)号：US20100167782A1
公开(公告)日：2010-07-01
申请号：US12715991
申请日：2010-03-02
申请人： Ronald L. Mahany , Steven E. Koenck , Alan G. Bunte , Robert C. Meier , Phillip Miller , Julie Ann Miller , Roger L. Wolf , George E. Hanson
发明人： Ronald L. Mahany , Steven E. Koenck , Alan G. Bunte , Robert C. Meier , Phillip Miller , Julie Ann Miller , Roger L. Wolf , George E. Hanson
IPC分类号： H04B1/38 , H04W88/02 , H04B7/005
CPC分类号： H04W92/02 , G06F1/163 , G06K2017/0051 , G06Q20/20 , G06Q20/32 , G06Q20/322 , G07G1/0018 , G07G1/0081 , G07G1/14 , H04B1/04 , H04L1/0002 , H04L1/0003 , H04L1/0025 , H04L1/0032 , H04L1/1671 , H04L1/1685 , H04L27/12 , H04L27/156 , H04L29/06 , H04L29/12009 , H04L61/00 , H04L69/18 , H04L69/329 , H04M7/006 , H04W52/267 , H04W84/12
摘要： A mobile customer service station operating within a wireless multi-hop communication network includes a console on a wheeled chassis. The console carries and houses a number of components which are used in merchandising operations to conclude customer purchase transactions. The items supported externally on the console are a printer for printing purchase receipts, customer credit charge agreements and records of transactions, and a magnetic card reader for reading information from a magnetic stripe of a customer's credit card. In one embodiment, the operation of the printer, credit card reader and the cash drawer is controlled by a multi-function control unit located within an enclosure of the console. The control unit is electrically powered by a self-contained power source which is preferably a deep cycle rechargeable battery. The console also houses a transceiver unit which under the control of the control unit is capable of interactive communication with a premises network. In another embodiment, the mobile service station comprises an access device which participates with a variety of peripherals at the station in a lower power communication LAN, while providing higher power communication to other network devices via a premises network with routing via a wireless spanning tree configuration.
摘要翻译：在无线多跳通信网络内操作的移动客户服务站包括在轮式底盘上的控制台。控制台携带并安装了用于商品销售操作的许多组件来完成客户购买交易。在控制台外部支持的物品是用于打印采购单，客户信用费用协议和交易记录的打印机，以及用于从客户信用卡的磁条读取信息的磁卡阅读器。在一个实施例中，打印机，信用卡读卡器和钱箱的操作由位于控制台的外壳内的多功能控制单元控制。控制单元由优选为深循环可充电电池的独立电源供电。控制台还容纳收发器单元，其在控制单元的控制下能够与房屋网络进行交互式通信。在另一个实施例中，移动服务站包括访问设备，该接入设备在较低功率通信LAN中的站点处参与各种外设，同时经由房屋网络向其他网络设备提供更高功率的通信，并通过无线生成树配置进行路由。

3. 发明申请

US20090046609A1 TRANSACTION CONTROL SYSTEM INCLUDING PORTABLE DATA TERMINAL AND MOBILE CUSTOMER SERVICE STATION 失效
标题翻译：包括便携式数据终端和移动客户服务站的交易控制系统
公开(公告)号：US20090046609A1
公开(公告)日：2009-02-19
申请号：US12258267
申请日：2008-10-24
申请人： Ronald L. Mahany , Steven E. Koenck , Alan G. Bunte , Robert C. Meier , Phillip Miller , Julie Ann Miller , Roger L. Wolf , George E. Hanson
发明人： Ronald L. Mahany , Steven E. Koenck , Alan G. Bunte , Robert C. Meier , Phillip Miller , Julie Ann Miller , Roger L. Wolf , George E. Hanson
IPC分类号： H04B7/00
CPC分类号： H04W92/02 , G06F1/163 , G06K2017/0051 , G06Q20/20 , G06Q20/32 , G06Q20/322 , G07G1/0018 , G07G1/0081 , G07G1/14 , H04B1/04 , H04L1/0002 , H04L1/0003 , H04L1/0025 , H04L1/0032 , H04L1/1671 , H04L1/1685 , H04L27/12 , H04L27/156 , H04L29/06 , H04L29/12009 , H04L61/00 , H04L69/18 , H04L69/329 , H04M7/006 , H04W52/267 , H04W84/12
摘要： A mobile customer service station operating within a wireless multi-hop communication network includes a console on a wheeled chassis. The console carries and houses a number of components which are used in merchandising operations to conclude customer purchase transactions. The items supported externally on the console are a printer for printing purchase receipts, customer credit charge agreements and records of transactions, and a magnetic card reader for reading information from a magnetic stripe of a customer's credit card. In one embodiment, the operation of the printer, credit card reader and the cash drawer is controlled by a multi-function control unit located within an enclosure of the console. The control unit is electrically powered by a self-contained power source which is preferably a deep cycle rechargeable battery. The console also houses a transceiver unit which under the control of the control unit is capable of interactive communication with a premises network. In another embodiment, the mobile service station comprises an access device which participates with a variety of peripherals at the station in a lower power communication LAN, while providing higher power communication to other network devices via a premises network with routing via a wireless spanning tree configuration.
摘要翻译：在无线多跳通信网络内操作的移动客户服务站包括在轮式底盘上的控制台。控制台携带并安装了用于商品销售操作的许多组件来完成客户购买交易。在控制台外部支持的物品是用于打印采购单，客户信用费用协议和交易记录的打印机，以及用于从客户信用卡的磁条读取信息的磁卡阅读器。在一个实施例中，打印机，信用卡读卡器和钱箱的操作由位于控制台的外壳内的多功能控制单元控制。控制单元由优选为深循环可充电电池的独立电源供电。控制台还容纳收发器单元，其在控制单元的控制下能够与房屋网络进行交互式通信。在另一个实施例中，移动服务站包括访问设备，该接入设备在较低功率通信LAN中的站点处参与各种外设，同时经由房屋网络向其他网络设备提供更高功率的通信，并通过无线生成树配置进行路由。

4. 发明授权

US5866554A Compositions for prevention of inflammation and adhesion formation and uses thereof 失效
标题翻译：用于预防炎症和粘连形成的组合物及其用途
公开(公告)号：US5866554A
公开(公告)日：1999-02-02
申请号：US684653
申请日：1996-07-19
申请人： Shalaby W. Shalaby , Julie Ann Miller
发明人： Shalaby W. Shalaby , Julie Ann Miller
IPC分类号： A61K31/715 , A61K33/06 , A61K45/06 , C08G18/08 , C08G18/63 , A61K31/70
CPC分类号： A61K31/728 , A61K31/715 , A61K33/06 , A61K45/06 , C08G18/14 , C08G18/632 , C08G2101/0008 , C08G2101/005 , C08G2101/0083
摘要： Pharmaceutical compositions comprising hyaluronic acid, non-steroidal inflammatory drugs, and organic salts of divalent metals, and methods of using these compositions for the inhibition of inflammation and adhesion formation are described.
摘要翻译：描述了包含透明质酸，非甾体炎症药物和二价金属的有机盐的药物组合物，以及使用这些组合物抑制炎症和粘附形成的方法。

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