专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5521082A Novel process for purification of hepatitis a virions 失效
标题翻译：用于纯化肝炎病毒粒子的新方法
公开(公告)号：US5521082A
公开(公告)日：1996-05-28
申请号：US967920
申请日：1992-10-28
申请人： John A. Lewis , Marcy E. Armstrong , Emilio A. Emini
发明人： John A. Lewis , Marcy E. Armstrong , Emilio A. Emini
IPC分类号： C12N7/02 , A61K39/29 , A61P31/12 , C12N7/00 , C12N7/04 , C12N7/08
CPC分类号： A61K39/29 , A61K39/12 , A61K2039/5254 , C12N2770/32434 , C12N2770/32451
摘要： New methods for purifying Hepatitis A virus (HAV) are to commercial scale-up and manufacture of specific HAV vaccines, including formalin-inactivated HAV and attenuated HAV.
摘要翻译：用于纯化甲型肝炎病毒（HAV）的新方法是商业化扩大和制造特定的HAV疫苗，包括福尔马林灭活的HAV和减毒的HAV。

2. 发明授权

US07094767B2 Polynucleotide herpes virus vaccine 失效
公开(公告)号：US07094767B2
公开(公告)日：2006-08-22
申请号：US09835699
申请日：2001-04-16
申请人： Marcy E. Armstrong , Robert D. Keys , John A. Lewis , Margaret A. Liu , William L. McClements
发明人： Marcy E. Armstrong , Robert D. Keys , John A. Lewis , Margaret A. Liu , William L. McClements
IPC分类号： A61K48/00
CPC分类号： C07K14/005 , A61K2039/51 , C12N2710/16622
摘要： Genes encoding herpes simplex virus type 2 (HSV-2) proteins were cloned into eukaryotic expression vectors to express the encoded proteins in mammalian muscle cells in vivo. Animals were immunized by injection of these DNA constructs, termed polynucleotide vaccines or PNV, into their muscles. In a DNA titration, it was found that a single immunization of ≧0.5 μg of (one) PNV, gave >90% seroconversion by ten weeks post immunization. Immune antisera neutralized both HSV-2 and HSV-1 in cell culture. When animals were challenged with HSV-2, significant (p

3. 发明授权

US5226894A Safety syringe assembly with radially deformable body 失效
标题翻译：带径向变形体的安全注射器组件
公开(公告)号：US5226894A
公开(公告)日：1993-07-13
申请号：US580931
申请日：1990-09-11
申请人： Terry M. Haber , William H. Smedley , Clark B. Foster , John A. Lewis
发明人： Terry M. Haber , William H. Smedley , Clark B. Foster , John A. Lewis
IPC分类号： A61M5/24 , A61M5/32 , A61M39/04
CPC分类号： A61M5/3243 , A61M5/24 , A61M2005/2407 , A61M2005/3246 , A61M2039/042 , A61M2205/582
摘要： The present invention is directed to a syringe assembly (48), particularly useful for use with conventional prefilled pharmaceutical cartridge-needle units (46), including a hollow body (4) housing the cartridge-needle unit or other syringe structure. The substantially hollow body and the syringe structure include mating slits (28, 29, 30) and a ring (26) so that the needle (60) can be exposed for I.M. injection use and then withdrawn into the body for safety. The body is configured so that when the user diametrically squeezes the body adjacent the slit(s), the ring disengages the slit(s) due to the deformation of the body which permits the needle tip (62) to be positioned inside, for safety, or outside, for use, of the body. The internal position is also useful for safely injecting a pharmaceutical into an IV port (88). When the invention is used with a conventional pharmaceutical cartridge-needle unit as the syringe structure, the body can be part of an enclosure unit (2) which acts as the packaging for the pharmaceutical cartridge-needle unit, as the body of the syringe for administration of I.V. and I.M. injections, and as individual integral sharps containment for safe antineedle-stick disposal of the used cartridge-needle unit.
摘要翻译：本发明涉及一种注射器组件（48），其特别适合于与常规的预填充药物 - 针单元（46）一起使用，所述预充式药物盒 - 针单元包括容纳所述药筒针单元或其它注射器结构的中空体。基本上中空的主体和注射器结构包括配合狭缝（28,29,30）和环（26），使得针（60）可以暴露以进行I.M.注射使用，然后将其抽出到身体中以获得安全。主体构造成使得当使用者在狭缝附近径向挤压主体时，环由于主体的变形而使缝隙脱离，这允许针尖（62）位于内部，以便安全，或外部，用于身体。内部位置也可用于将药物安全注入IV口（88）。当本发明与常规药筒针单元一起用作注射器结构时，主体可以是用作药筒 - 针单元的包装的外壳单元（2）的一部分，作为注射器的主体管理IV 和I.M.注射剂，以及作为单独的整体式锐器保护装置，用于使用过的筒形针单元的安全的针刺处理。

4. 发明授权

US4867172A Collapsible blood collector 失效
标题翻译：可折叠的血液收集器
公开(公告)号：US4867172A
公开(公告)日：1989-09-19
申请号：US159374
申请日：1988-02-23
申请人： Terry M. Haber , John A. Lewis
发明人： Terry M. Haber , John A. Lewis
IPC分类号： A61B5/15 , A61M5/178 , A61M5/31 , A61M5/32
CPC分类号： A61M5/3275 , A61B5/15003 , A61B5/150305 , A61B5/150389 , A61B5/150496 , A61B5/150572 , A61B5/150671 , A61B5/150732 , A61B5/154 , A61M5/3129 , A61M2005/3247
摘要： A low-cost, disposable blood collector which may be collapsed into a low volume disposal package, whereby to maximize both safety and efficiency when discarding the blood collector after use. The blood collector comprises a hollow, collapsible blood collection tube holder for receiving an evacuated blood collection tube, a double-ended hypodermic needle cannula for making a veni puncture and drawing a sample of a patient's blood to a blood collection tube at the interior of the blood collection tube holder, and a collapsible needle cover which surrounds the distal end of the needle cannula. The blood collection tube holder is collapsible from an open, cylindrical configuration, at which to receive a blood collection tube therewithin, to a closed, generally planar configuration, with the blood collection tube removed therefrom. The needle cover is collapsible from an open, expanded configuration, at which the distal end of the needle cannula is exposed for making a veni puncture through the patient's skin, to a closed, generally planar configuration, at which to surround and shield the distal end of the cannula and thereby avoid an accidental needle strike.
摘要翻译：一种低成本的一次性血液收集器，其可能被折叠成低体积的处理包装，从而在使用后丢弃血液收集器时最大化安全性和效率。血液收集器包括用于接收抽空的采血管的中空的可收缩的采血管保持器，用于制造静脉穿刺并将患者血液样本抽吸到血液收集管内的采血管的双端皮下注射针管采血管保持器和围绕针插管的远端的可折叠的针罩。采血管保持器从开放的圆柱形构造可收缩，在其中将血液收集管接收到封闭的大体上平面的构型上，其中取出血液采集管。针盖可以从打开的扩展构型折叠，在该开口处，针插管的远端暴露以使得静脉穿刺穿过患者的皮肤到封闭的大体上平面的构造，围绕并屏蔽远端的插管，从而避免意外的针刺。

5. 发明授权

US4044734A Exhaust gas recirculation valve malfunction indicator apparatus 失效
标题翻译：排气再循环阀故障指示仪
公开(公告)号：US4044734A
公开(公告)日：1977-08-30
申请号：US691263
申请日：1976-05-28
申请人： John A. Lewis
发明人： John A. Lewis
IPC分类号： F01L1/34 , F02M25/06
CPC分类号： F01L1/34
摘要： An internal combustion engine provided with an exhaust gas recirculating (EGR) system containing a vacuum/electric switch assembly activated in response to a non-movement type malfunction of the EGR valve to energize a warning light.
摘要翻译：具有排气再循环（EGR）系统的内燃机，其包含真空/电开关组件，所述真空/电开关组件响应于EGR阀的不运动型故障而激活，以激励警告灯。

6. 发明授权

US5333971A Interlocking bulkhead 失效
标题翻译：联锁舱壁
公开(公告)号：US5333971A
公开(公告)日：1994-08-02
申请号：US970562
申请日：1992-11-03
申请人： John A. Lewis
发明人： John A. Lewis
IPC分类号： E02D5/28 , E02D5/00 , E02D7/20
CPC分类号： E02D5/28
摘要： A bulkhead member for assembling a bulkhead is disclosed, comprising a body having two opposed faces and first and second substantially parallel edges. The first edge includes an integral split socket and the second edge includes an integral connecting bead. At least one of the opposed faces includes a planar surface, and one of the socket and bead is mounted adjacent the planar surface. The connecting bead is angled with respect to the planar surface, and the gap in the split socket is correlatively angled, such that when the bead of the first bulkhead member is lockingly received in the socket of another like bulkhead member, the planar surfaces of the two bulkhead members may be substantially coplanar, and the connecting bead and socket of the two bulkhead members are offset from the common plane of the planar surfaces of the two bulkhead members.
摘要翻译：公开了一种用于组装隔板的隔板构件，包括具有两个相对面的主体和第一和第二基本上平行的边缘。第一边缘包括整体分离插座，第二边缘包括整体连接珠。相对面中的至少一个包括平面，并且插座和珠中的一个安装在平面附近。连接凸缘相对于平坦表面成角度，并且分离插座中的间隙相关地成角度，使得当第一隔板构件的凸缘被锁定地容纳在另一个类似的隔板构件的插座中时，平面表面两个隔板构件可以是基本上共面的，并且两个隔板构件的连接胎圈和插座从两个隔板构件的平坦表面的公共平面偏移。

7. 发明授权

US3955364A Engine deceleration vacuum differential valve control 失效
标题翻译：发动机减速真空差压阀控制
公开(公告)号：US3955364A
公开(公告)日：1976-05-11
申请号：US430818
申请日：1974-01-04
申请人： John A. Lewis
发明人： John A. Lewis
IPC分类号： F01N3/22 , F02B75/10
CPC分类号： F01N3/227 , F01N3/22 , F01N2390/06 , Y10S261/19
摘要： A valve located in an engine intake manifold vacuum line is operated by differential vacuum forces to temporarily open an air bleed during engine deceleration high manifold vacuums to apply atmospheric pressure to a vacuum controlled unit that then bypasses air away from a catalytic converter and the engine to protect the converter and prevent backfire.
摘要翻译：位于发动机进气歧管真空管路中的阀门通过差分真空力来操作，以在发动机减速期间临时打开空气泄放高歧管真空，以将真空控制单元施加大气压力，然后将空气从催化转化器和发动机旁路保护转换器并防止回火。

8. 发明授权

US4813935A Urinary catheter 失效
标题翻译：导尿管
公开(公告)号：US4813935A
公开(公告)日：1989-03-21
申请号：US78103
申请日：1987-07-27
申请人： Terry M. Haber , John A. Lewis , Clark B. Foster
发明人： Terry M. Haber , John A. Lewis , Clark B. Foster
IPC分类号： A61M25/04
CPC分类号： A61M25/04 , A61M25/0017 , A61M2025/0018
摘要： An improved urinary catheter having a unique, low volume device by which to retain the catheter within the bladder, so that urine can be removed therefrom. The retaining device consumes less volume in the bladder than that which would ordinarily be consumed by a conventional Foley-style balloon, whereby both the frequency and severity of urinary bladder spasms, which are induced by pressure against the trigonal area of the bladder, can be reduced. What is more, the retaining device is advantageously adapted to provide little resistance, and thereby minimize any damage to the urinary tract, in the event that a patient should suddenly and forceably attempt to remove the catheter from his bladder.
摘要翻译：一种改进的导尿管，其具有独特的低体积装置，通过该装置将导管保持在膀胱内，使得可以从其中移除尿液。保持装置消耗的膀胱体积比通常由常规的Foley型气囊消耗的体积小，由此压迫膀胱三角区域的膀胱痉挛的频率和严重程度可以是减少此外，如果患者应该突然且有力地试图将导管从他的膀胱中移除，则保持装置有利地适于提供很小的阻力，从而使对尿道的任何损伤最小化。

9. 发明授权

US4296447A Magnetic recording and reproduction 失效
标题翻译：磁记录和再现
公开(公告)号：US4296447A
公开(公告)日：1981-10-20
申请号：US102540
申请日：1979-12-11
申请人： John A. Lewis
发明人： John A. Lewis
IPC分类号： G11B5/00 , G11B5/33 , G11B5/39 , G11B5/30
CPC分类号： G11B5/3903 , G11B5/33 , G11B5/39 , G11B2005/0018 , G11B5/3948
摘要： A magnetic tape recording head comprises a strip of magneto-resistive material whose magnetic field/resistance change characteristic is in the form of two mirror image nonlinear curves starting at the origin of the graph. The strip is energized with a constant current and the voltage across it is fed to two sample and hold circuits. These are respectively triggered by antiphase pulses and the samples from the two sample and hold circuits are fed to the respective inputs of a differential amplifier. A bias conductor alongside the magneto-resistive strip is energized with pulses having the same polarity as, and synchronous with, the sampling pulses so as to bias the strip to predetermined points which are alternately on the positive and negative parts of the graph. The overall effective characteristic is therefore the sum of one part of the graph and the inverted other part, and is substantially linear.
摘要翻译：磁带记录头包括一个磁阻材料条，其磁场/电阻变化特征是从图的原点开始的两个镜像非线性曲线的形式。该带通过恒定电流通电，并且其上的电压被馈送到两个采样和保持电路。这些分别由反相脉冲触发，并且来自两个采样和保持电路的样本被馈送到差分放大器的相应输入。与磁阻带一起的偏置导体由与采样脉冲具有相同极性并且与其同步的脉冲激励，以便将条偏置到交替地在图的正负部分上的预定点。因此，整体有效特性是图的一部分和反转的其它部分的和，并且基本上是线性的。

10. 发明授权

US3930475A Engine exhaust gas recirculating control 失效
标题翻译：发动机排气再循环控制
公开(公告)号：US3930475A
公开(公告)日：1976-01-06
申请号：US391411
申请日：1973-08-24
申请人： John A. Lewis , John R. Marshall
发明人： John A. Lewis , John R. Marshall
IPC分类号： F02M25/07 , F02M25/06
CPC分类号： F02M26/56
摘要： The engine has a duct connecting the gases in the exhaust gas crossover passage to the intake manifold, the duct normally being closed by a valve that is opened by manifold vacuum that is modulated as a function of carburetor throttle blade opening and connected to the duct past an air-bleed device that normally is open and closed against a spring force by unmodulated manifold vacuum below a predetermined level so that the gas recirculating valve opening signal force varies directly with manifold vacuum decreases to prevent recirculation during engine idle and cruising and wide-open throttle operations while providing controlled operation in the engine accelerating range between.
摘要翻译：发动机具有将废气交叉通道中的气体连接到进气歧管的管道，管道通常由通过歧管真空打开的阀门关闭，该歧管被调节为化油器节流阀开度并连接到管道过去的功能一个排气装置，通常通过未调节的歧管真空度低于预定水平而通过弹簧力打开和关闭，使得气体再循环阀打开信号力直接与歧管真空度变化减小，以防止在发动机空转和巡航和大开度期间的再循环节气门操作，同时在发动机加速范围内提供受控操作。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式