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1. 发明授权

US4767414A Ionizing plasma lubricant method 失效
标题翻译：电离等离子体润滑方法
公开(公告)号：US4767414A
公开(公告)日：1988-08-30
申请号：US36733
申请日：1987-04-10
申请人： Joel L. Williams , David A. Martin , David B. Montgomery
发明人： Joel L. Williams , David A. Martin , David B. Montgomery
IPC分类号： A61M5/31 , B05D3/14 , B05D5/08 , B29C59/14 , A61M5/315
CPC分类号： B05D3/148 , A61M5/31 , B29C59/14 , B05D5/08
摘要： A method to reduce high breakout and sustaining forces between slidable surfaces includes applying a film of lubricant to at least one of the surfaces and subjecting the lubricant and surface to an ionizing plasma. The invention includes articles having slidable surfaces of low breakout and sustaining forces.
摘要翻译：减少可滑动表面之间的高突破和持续力的方法包括将润滑剂膜施加到至少一个表面并使润滑剂和表面经受电离等离子体。本发明包括具有低突出和维持力的滑动表面的制品。

2. 发明授权

US4822632A Ionizing plasma lubricant method 失效
标题翻译：电离等离子体润滑方法
公开(公告)号：US4822632A
公开(公告)日：1989-04-18
申请号：US190028
申请日：1988-05-04
申请人： Joel L. Williams , David A. Martin , David B. Montgomery
发明人： Joel L. Williams , David A. Martin , David B. Montgomery
IPC分类号： A61M5/31 , B05D3/14 , B05D5/08 , B29C59/14 , B05D1/08
CPC分类号： B05D3/148 , A61M5/31 , B29C59/14 , B05D5/08
摘要： A method to reduce high breakout and sustaining forces between slidable surfaces includes applying a film of lubricant to at least one of the surfaces and subjecting the lubricant and surface to an ionizing plasma. The invention includes articles having slidable surfaces of low breakout and sustaining forces.
摘要翻译：减少可滑动表面之间的高突破和持续力的方法包括将润滑剂膜施加到至少一个表面并使润滑剂和表面经受电离等离子体。本发明包括具有低突出和维持力的滑动表面的制品。

3. 发明授权

US4452679A Substrate with chemically modified surface and method of manufacture thereof 失效
标题翻译：具有化学改性表面的基体及其制造方法
公开(公告)号：US4452679A
公开(公告)日：1984-06-05
申请号：US526297
申请日：1983-08-25
申请人： Terry S. Dunn , David B. Montgomery , Joel L. Williams
发明人： Terry S. Dunn , David B. Montgomery , Joel L. Williams
IPC分类号： B05D3/06 , C03C23/00 , C04B41/45 , C04B41/81 , C23C8/36 , C30B33/00 , C07C17/00
CPC分类号： C08J7/123 , C03C23/006 , C04B41/4505 , C04B41/81 , C23C8/36 , C30B33/00
摘要： A method for providing specific chemical functional groups on a substrate surface is provided. In the method a vaporized material is introduced into a reaction zone to produce a plasma. Selective species of the plasma are prevented from contacting the substrate surface while the remaining species are contacted with the substrate.
摘要翻译：提供了一种在衬底表面上提供特定化学官能团的方法。在该方法中，将气化材料引入反应区以产生等离子体。防止等离子体的选择性物质与基底表面接触，同时剩余的物质与基底接触。

4. 发明授权

US4967763A Platelet stable blood collection assembly 失效
标题翻译：血小板稳定采血组
公开(公告)号：US4967763A
公开(公告)日：1990-11-06
申请号：US322474
申请日：1989-03-13
申请人： Edward Nugent , Robert J. Losada , Hugh T. Conway , David B. Montgomery , Joel L. Williams
发明人： Edward Nugent , Robert J. Losada , Hugh T. Conway , David B. Montgomery , Joel L. Williams
IPC分类号： A61B5/15 , A61B5/151 , B01L3/14 , B29C59/14
CPC分类号： B01L3/5082 , A61B5/150022 , A61B5/150213 , A61B5/150343 , B29C59/142
摘要： A blood collection assembly includes a plasma-treated blood collection container and a blood collector which optionally may also be plasma-treated. The collector has a body portion providing a blood passageway between the container and a scoop shaped portion which contacts a puncture wound. A vent in the collector allows air displacement from the container when blood enters. The inside wall of the container has longitudinal ribs molded thereon and an altered surface chemistry characterized by an enhanced oxygen content. The invention includes a method to increase blood flow across the interior surface of a plastic blood collection container comprising plasma treatment of the surface.

5. 发明授权

US4948628A Method for plasma treatment of small diameter tubes 失效
标题翻译：小直径管等离子体处理方法
公开(公告)号：US4948628A
公开(公告)日：1990-08-14
申请号：US335476
申请日：1989-04-10
申请人： David B. Montgomery , Joel L. Williams
发明人： David B. Montgomery , Joel L. Williams
IPC分类号： A61F2/06 , C23C16/04 , C23C16/509
CPC分类号： C23C16/045 , A61F2/062 , C23C16/509
摘要： An apparatus for generating a plasma in the lumen of a small diameter tube includes a housing having a diaphragm which separates the housing into a first chamber equipped with a gas inbleed assembly and a second chamber connected to a vacuum source. Parallel plate electrodes in the first chamber are encased in a dielectric which prevents substantially all plasma discharge external of a plasma zone between the electrodes. A conduit maintains gas flow between the chambers. A bore through the dielectric includes the plasma zone and receives the tube to be plasma treated.A method for treating the luminal wall of a plastic tube includes positioning a tube in the plasma zone, evacuating the chambers, bleeding a gas into the chambers, and delivering radiofrequency power to the electrodes. A long tube may be drawn through the plasma zone, or the dielectric and electrodes may be moved past the tube.
摘要翻译：一种用于在小直径管的内腔中产生等离子体的装置包括具有隔膜的壳体，该膜片将壳体分离成装备有气体入口组件的第一室和连接到真空源的第二室。第一室中的平行平板电极被封装在电介质中，该绝缘体基本上防止电极之间的等离子体区域外部的所有等离子体放电。导管保持室之间的气流。穿过电介质的孔包括等离子体区并接收待等离子体处理的管。用于处理塑料管的腔壁的方法包括将管定位在等离子体区域中，抽空腔室，将气体排放到腔室中，并将射频功率传送到电极。可以通过等离子体区域拉伸长管，或者电介质和电极可以移动经过管。

6. 发明授权

US4927676A Method for rapid adherence of endothelial cells onto a surface and surfaces prepared thereby 失效
标题翻译：内皮细胞快速粘附到由其制备的表面和表面上的方法
公开(公告)号：US4927676A
公开(公告)日：1990-05-22
申请号：US340190
申请日：1989-04-19
申请人： Joel L. Williams , David B. Montgomery , Lillian P. Baldwin
发明人： Joel L. Williams , David B. Montgomery , Lillian P. Baldwin
IPC分类号： A61L27/50 , A61L33/00 , A61L33/18
CPC分类号： A61L27/507 , A61L33/0094 , A61L33/18 , Y10T428/1386 , Y10T428/2913 , Y10T428/31551 , Y10T428/31786 , Y10T428/31938
摘要： Small diameter plastic tubing is plasma-treated on the lumen wall and endothelial cells are adhered thereto to give antithrombogenic small diameter conduits useful for vascular grafts and other articles intended to come in contact with blood.
摘要翻译：在管腔壁上对小直径的塑料管进行等离子体处理，并且将内皮细胞粘附到其上以产生用于血管移植物和旨在与血液接触的其它物品的抗血栓形成小直径导管。

7. 发明授权

US4846101A Apparatus for plasma treatment of small diameter tubes 失效
标题翻译：用于小直径管等离子体处理的装置
公开(公告)号：US4846101A
公开(公告)日：1989-07-11
申请号：US214244
申请日：1988-07-01
申请人： David B. Montgomery , Joel L. Williams
发明人： David B. Montgomery , Joel L. Williams
IPC分类号： A61L33/00 , A61F2/06 , C08J7/00 , C23C16/04 , C23C16/509
CPC分类号： C23C16/045 , A61F2/062 , C23C16/509
摘要： An apparatus for generating a plasma in the lumen of a small diameter tube includes a housing having a diaphragm which separates the housing into a first chamber equipped with a gas inbleed assembly and a second chamber connected to a vacuum source. Parallel plate electrodes in the first chamber are encased in a dielectric which prevents substantially all plasma discharge external of a plasma zone between the electrodes. A conduit maintains gas flow between the chambers. A bore through the dielectric includes the plasma zone and receives the tube to be plasma treated.A method for treating the luminal wall of a plastic tube includes positioning a tube in the plasma zone, evacuating the chambers, bleeding a gas into the chambers, and delivering radiofrequency power to the electrodes. A long tube may be drawn through the plasma zone, or the dielectric and electrodes may be moved past the tube.

8. 发明授权

US5744087A Medical articles and method therefor 失效
标题翻译：医疗用品及其方法
公开(公告)号：US5744087A
公开(公告)日：1998-04-28
申请号：US311985
申请日：1994-09-26
申请人： Joel L. Williams , Hugh T. Conway
发明人： Joel L. Williams , Hugh T. Conway
IPC分类号： A61L33/00 , B29C43/00 , B29C43/06 , B29K21/00 , B29K23/00 , B29L31/00 , C08L21/00 , C08L23/06 , B28B3/06 , B28B5/00
CPC分类号： B29C43/00 , B29L2031/56
摘要： A medical article of a polymeric nonthermoplastic material and method therefor is made by a continuous compression molding method in which a predetermined quantity of the polymer is added sequentially to a series of molds on a track.
摘要翻译：聚合物非热塑性材料的医疗制品及其制造方法是通过连续压缩成型法制备的，其中将预定量的聚合物依次添加到轨道上的一系列模具中。

9. 发明授权

US5616369A Process for barrier coating of plastic objects 失效
标题翻译：塑料物件的阻隔涂层工艺
公开(公告)号：US5616369A
公开(公告)日：1997-04-01
申请号：US265173
申请日：1994-06-24
申请人： Joel L. Williams , Susan L. Burkett , Shel McGuire
发明人： Joel L. Williams , Susan L. Burkett , Shel McGuire
IPC分类号： A61L31/08 , C23C14/02 , C23C14/46 , C23C16/02 , C23C16/40 , C23C16/44 , C23C16/50 , H05H1/00
CPC分类号： A61L31/088 , A61L31/084 , C23C14/022 , C23C14/46 , C23C16/0254 , C23C16/0272 , C23C16/401 , C23C16/4401 , C23C16/50
摘要： A method for sequentially depositing a silicon oxide based film as a barrier on a substrate. The film is useful for providing an effective barrier against gas permeability in containers and for extending shelf-life of containers, especially plastic evacuated blood collection devices.
摘要翻译：一种用于在基板上依次沉积氧化硅基膜作为阻挡层的方法。该膜可用于提供容器中气体渗透性的有效屏障，并延长容器，特别是塑料抽空采血装置的保存期限。

10. 发明授权

US4782647A Flexible packaging and the method of production 失效
标题翻译：柔性包装和生产方法
公开(公告)号：US4782647A
公开(公告)日：1988-11-08
申请号：US109679
申请日：1987-10-08
申请人： Joel L. Williams , Walter P. Miller, III
发明人： Joel L. Williams , Walter P. Miller, III
IPC分类号： B65B9/02 , B65B47/02 , B65B61/00
CPC分类号： B65B9/023 , A61F2013/0296 , A61K9/703 , A61K9/7084
摘要： Methods are provided for producing flexible packages and particularly transdermal medication patches. The method includes the continuous and rapid production of a plurality of such packages while continuously treating one portion of the laminate forming the package by corona discharge in order to modify the surface adhesion properties thereof to provide, simultaneously, a proper seal of a transdermal membrane in the laminate forming the package, while maintaining the desired medication dispensing properties thereof.
摘要翻译：提供了用于生产柔性包装和特别是透皮药物贴剂的方法。该方法包括连续快速地生产多个这样的包装，同时通过电晕放电连续地处理形成包装的层压体的一部分，以便改变其表面粘合性能，同时提供透皮膜的适当密封形成包装的层压体，同时保持所需的药物分配性质。

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