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1. 发明申请

US20110006011A1 METHOD FOR THE ELUTION OF 18F FLUORIDE TRAPPED ON AN ANION-EXCHANGE PHASE IN A FORM SUITABLE FOR EFFICIENT RADIOLABELING WITHOUT ANY EVAPORATION STEP 有权
标题翻译：用于在无任何蒸发步骤的情况下用于有效放射性物质的形式的阴离子交换相上的18F氟化物溶液的方法
公开(公告)号：US20110006011A1
公开(公告)日：2011-01-13
申请号：US12528284
申请日：2008-02-19
申请人： Joel Aerts , Christian Lemaire , Steve Lignon , Andre Luxen , Jean-Luc Morelle , Gauthier Philippart , Samuel Voccia
发明人： Joel Aerts , Christian Lemaire , Steve Lignon , Andre Luxen , Jean-Luc Morelle , Gauthier Philippart , Samuel Voccia
IPC分类号： B01D15/36
CPC分类号： C22B3/42 , A61K51/04 , B01D15/363 , B01D15/426 , C01B9/08 , C02F2001/422 , C02F2101/14 , G21G4/08 , Y02P10/234
摘要： A method extracts out of an aqueous solution, concentrate and/or reformulate [18F] fluorides without any evaporation step. The eluting solution is a low water content, preferably
摘要翻译：在没有任何蒸发步骤的情况下，从水溶液中提取出方法，浓缩和/或重整[18 F]氟化物。洗脱溶液是低水含量，优选<3％的水，有机溶液至少含有：作为叔醇官能的分子的第一化合物（A），适合于相转移剂的第二化合物（B）用于放射性标记，这是阴离子交换过程所必需的。

2. 发明申请

US20100243972A1 METHOD FOR THE PREPARATION OF REACTIVE [18] F FLUORIDE 有权
标题翻译：反应性[18]氟化物的制备方法
公开(公告)号：US20100243972A1
公开(公告)日：2010-09-30
申请号：US12596254
申请日：2008-04-22
申请人： Samuel Voccia , Joél Aerts , Christian Lemaire , André Luxen , Jean-Luc Morelle , Gauthier Philippart
发明人： Samuel Voccia , Joél Aerts , Christian Lemaire , André Luxen , Jean-Luc Morelle , Gauthier Philippart
IPC分类号： C09K11/04
CPC分类号： C01B9/08 , C01P2006/88 , C02F2001/422 , C02F2101/006 , C02F2101/14
摘要： The present invention is related to a method to obtain reactive [18F] fluorides in an organic medium suitable for radiolabelling without any azeotropic evaporation step, by the use of a solid phase extraction column containing a modified non-ionic solid support.
摘要翻译：本发明涉及通过使用含有改性的非离子固体支持物的固相萃取塔，在适于放射性标记而不进行任何共沸蒸发步骤的有机介质中获得反应性[18 F]氟化物的方法。

3. 发明授权

US08641903B2 Method for the preparation of reactive [18] F fluoride 有权
标题翻译：氟化物的制备方法
公开(公告)号：US08641903B2
公开(公告)日：2014-02-04
申请号：US12596254
申请日：2008-04-22
申请人： Samuel Voccia , Joël Aerts , Christian Lemaire , André Luxen , Jean-Luc Morelle , Gauthier Philippart
发明人： Samuel Voccia , Joël Aerts , Christian Lemaire , André Luxen , Jean-Luc Morelle , Gauthier Philippart
IPC分类号： B01D11/00 , B01D15/08 , B01D15/36 , B01D15/42 , A61K51/00 , C01B7/20 , C01B9/08 , C09K11/04
CPC分类号： C01B9/08 , C01P2006/88 , C02F2001/422 , C02F2101/006 , C02F2101/14
摘要： The present invention is related to a method to obtain reactive [18F] fluorides in an organic medium suitable for radiolabelling without any azeotropic evaporation step, by the use of a solid phase extraction column containing a modified non-ionic solid support.
摘要翻译：本发明涉及通过使用含有改性的非离子固体支持物的固相萃取塔，在适于放射性标记而不进行任何共沸蒸发步骤的有机介质中获得反应性[18 F]氟化物的方法。

4. 发明申请

US20100196254A1 METHOD FOR THE DIRECT ELUTION OF REACTIVE 18F FLUORIDE FROM AN ANION EXCHANGE RESIN IN AN ORGANIC MEDIUM SUITABLE FOR RADIOLABELLING WITHOUT ANY EVAPORATION STEP BY THE USE OF STRONG ORGANIC BASES 有权
标题翻译：用于直接吹扫18F氟化物的方法直接用于有机介质的有机介质，适用于通过使用强有机基体而无任何蒸发步骤进行放射性吸收
公开(公告)号：US20100196254A1
公开(公告)日：2010-08-05
申请号：US12664615
申请日：2008-07-01
申请人： Christian Lemaire , Samuel Voccia , Joël Aerts , André Luxen , Jean-Luc Morelle , Gauthier Philipart
发明人： Christian Lemaire , Samuel Voccia , Joël Aerts , André Luxen , Jean-Luc Morelle , Gauthier Philipart
IPC分类号： C01B7/20
CPC分类号： B01D15/363
摘要： A method to extract out of an aqueous solution, concentrate and/or reformulate [18F] fluorides without any evaporation step wherein the eluting solution is a organic solution having a water content
摘要翻译：在没有任何蒸发步骤的情况下从水溶液中萃取出浓缩和/或重整[18 F]氟化物的方法，其中洗脱溶液是水含量<3％的有机溶液。该溶液至少含有：适用于随后的放射性标记反应的有机溶剂; 第一化合物（A），其是含有至少一个酸性氢的分子和第二化合物（B），其是足够强的能够将第一化合物（A）的酸性氢在酸 - 导致形成有机盐（S）的碱反应。

5. 发明授权

US08491790B2 Method for the direct elution of reactive 18F fluoride from an anion exchange resin in an organic medium suitable for radiolabelling without any evaporation step by the use of strong organic bases 有权
标题翻译：在适合于放射性标记的有机介质中通过使用强有机碱直接洗脱活性18 F氟化物从阴离子交换树脂直接洗脱而无任何蒸发步骤的方法
公开(公告)号：US08491790B2
公开(公告)日：2013-07-23
申请号：US12664615
申请日：2008-07-01
申请人： Christian Lemaire , Samuel Voccia , Joël Aerts , André Luxen , Jean-Luc Morelle , Gauthier Philipart
发明人： Christian Lemaire , Samuel Voccia , Joël Aerts , André Luxen , Jean-Luc Morelle , Gauthier Philipart
IPC分类号： B01D15/08
CPC分类号： B01D15/363
摘要： A method to extract out of an aqueous solution, concentrate and/or reformulate [18F] fluorides without any evaporation step wherein the eluting solution is a organic solution having a water content
摘要翻译：在没有任何蒸发步骤的情况下从水溶液中萃取出浓缩和/或重整[18 F]氟化物的方法，其中洗脱溶液是水含量<3％的有机溶液。该溶液至少含有：适用于随后的放射性标记反应的有机溶剂; 第一化合物（A），其是含有至少一个酸性氢的分子和第二化合物（B），其是足够强的能够将第一化合物（A）的酸性氢在酸 - 导致形成有机盐（S）的碱反应。

6. 发明授权

US5858791A Method and device for the continuous measurement of variations in the overall saturation of a sample with incompressible immiscible fluids 失效
标题翻译：用于连续测量具有不可压缩不混溶流体的样品的总体饱和度变化的方法和装置
公开(公告)号：US5858791A
公开(公告)日：1999-01-12
申请号：US931944
申请日：1997-09-17
申请人： Christian Lemaire
发明人： Christian Lemaire
IPC分类号： G01N15/08 , G01N33/24
CPC分类号： G01N33/241 , G01N15/0826 , G01N33/24 , Y10S436/908
摘要： Saturation variations are obtained by displacing a first fluid (for example water) that initially saturates a sample (1) coated with resin (2) by injecting therein, through a first end plate or cap (3) and by means of a pump (7), a second fluid (for example oil). The mixture flowing out through an opposite end plate (4) is collected in an initially filled two-phase separator (9) placed on an electronic balance (10). The first excess fluid flows towards a vessel (13), and the progressive accumulation of the second fluid in separator (9) leads to a variation in the total weight. A programmed processor (14) computes permanently the saturation values of the sample with respect to the first and to the second fluid, from the measured weight variations of separator (9). The method and device can be used for laboratory measurements of rock samples for example.
摘要翻译：饱和度变化是通过使第一流体（例如水）首先通过第一端板或盖（3）和泵（7）中的注入而使涂覆有树脂（2）的样品（1）饱和的第一流体（例如水）），第二流体（例如油）。通过相对端板（4）流出的混合物被收集在放置在电子天平（10）上的初始填充的两相分离器（9）中。第一多余流体朝向容器（13）流动，并且第二流体在分离器（9）中的逐渐累积导致总重量的变化。编程处理器（14）根据所测量的分离器（9）的重量变化，永久地计算样品相对于第一和第二流体的饱和度值。该方法和装置可用于例如岩石样品的实验室测量。

7. 发明授权

US5602340A Selective pressure tap for a pressure detector 失效
标题翻译：用于压力检测器的选择性压力分接头
公开(公告)号：US5602340A
公开(公告)日：1997-02-11
申请号：US575042
申请日：1995-12-19
申请人： Christian Lemaire , Fran.cedilla.ois Kalaydjian
发明人： Christian Lemaire , Fran.cedilla.ois Kalaydjian
IPC分类号： G01L19/00 , G01L7/00
CPC分类号： G01L19/0007
摘要： A selective pressure tap is used for measuring, at a point of a porous sample containing at least two distinct fluids such as water and oil for example and placed in a case or sheath, the pressure exerted selectively by one of the fluids. It comprises a body provided with a central channel that is externally threaded over part of its length so as to be screwed into a hole provided through the sheath. The body of the pressure tap comprises a ferrule externally provided with 0-ring seals. The end face of the ferrule is suited for pressing closely against the wall of the sample, during the screwing operation, one or several semipermeable membranes permeable to the fluid in question. The central channel communicates with a pressure detector through a pipe.
摘要翻译：选择性压力分接头用于在包含例如水和油的至少两种不同流体（例如水和油）的多孔样品的点处测量，并且放置在壳或壳中，由一种流体选择性地施加压力。它包括设置有中心通道的主体，该中心通道在其长度的一部分上被外螺纹拧入到通过护套提供的孔中。压头的主体包括外部设置有O形密封圈的套圈。套圈的端面适于在螺旋操作期间紧紧地压靠在样品的壁上，一个或多个可渗透所述流体的半透膜。中央通道通过管道与压力检测器连通。

8. 发明授权

US08501868B2 Thermoplastic molding compositions with improved optical properties 失效
标题翻译：具有改善光学性能的热塑性模塑组合物
公开(公告)号：US08501868B2
公开(公告)日：2013-08-06
申请号：US13072099
申请日：2011-03-25
申请人： Matthias Müller , Ludger Leber , Achim Datko , Leonie Felicitas Braun , Christian Lemaire , Piyada Charoensirisomboon , Michel Pepers
发明人： Matthias Müller , Ludger Leber , Achim Datko , Leonie Felicitas Braun , Christian Lemaire , Piyada Charoensirisomboon , Michel Pepers
IPC分类号： C08L33/12 , C08L51/06 , C08L25/12 , C08L33/20 , C08L51/04
CPC分类号： C08L33/12 , C08F285/00 , C08L25/00 , C08L51/003 , C08L51/04 , C08L2207/53 , C08L25/12 , C08F212/08
摘要： The present invention relates to thermoplastic molding compositions having a mixture of (a) from 10 to 50% by weight of a methyl methacrylate polymer as component (A), from 20 to 60% by weight of a copolymer as component (B), and from 20 to 70% by weight of a graft copolymer as component (C). Component (C) is obtainable from components (c1) a core, (c2) a first graft shell, and (c3) a second graft shell. The second graft shell (c3) is obtainable via polymerization of a C1-C8-alkyl ester of methacrylic acid as component (c31) and a further vinylaromatic monomer as component (c32). Graft copolymer (C) is produced via emulsion polymerization and is isolated from the reaction mixture by precipitation resulting from shear. Also disclosed are processes for producing the molding compositions, the use of the molding compositions, and moldings obtainable from the molding compositions.
摘要翻译：本发明涉及具有（a）10至50重量％的作为组分（A）的甲基丙烯酸甲酯聚合物，20至60重量％的作为组分（B）的共聚物的混合物的热塑性模塑组合物，以及 20〜70重量％的作为组分（C）的接枝共聚物。组分（C）可从组分（c1）芯，（c2）第一接枝壳和（c3）第二接枝壳获得。第二接枝壳（c3）可通过作为组分（c31）的甲基丙烯酸的C 1 -C 8烷基酯和作为组分（c32）的另外的乙烯基芳族单体的聚合获得。接枝共聚物（C）通过乳液聚合制备，并通过剪切产生的沉淀从反应混合物中分离。还公开了用于生产模塑组合物的方法，模塑组合物的使用以及可从成型组合物获得的模制品。

9. 发明申请

US20110237749A1 THERMOPLASTIC MOLDING COMPOSITIONS WITH IMPROVED OPTICAL PROPERTIES 失效
标题翻译：具有改进的光学性质的热塑性成型组合物
公开(公告)号：US20110237749A1
公开(公告)日：2011-09-29
申请号：US13072099
申请日：2011-03-25
申请人： Matthias Müller , Ludger Leber , Achim Datko , Leonie Felicitas Braun , Christian Lemaire , Piyada Charoensirisomboon , Michel Pepers
发明人： Matthias Müller , Ludger Leber , Achim Datko , Leonie Felicitas Braun , Christian Lemaire , Piyada Charoensirisomboon , Michel Pepers
IPC分类号： C08L51/06 , C08L33/12 , C08L33/20
CPC分类号： C08L33/12 , C08F285/00 , C08L25/00 , C08L51/003 , C08L51/04 , C08L2207/53 , C08L25/12 , C08F212/08
摘要： The present invention relates to thermoplastic molding compositions comprising a mixture of (a) from 10 to 50% by weight, based on the entirety of components (A), (B), and (C), of a methyl methacrylate polymer as component (A), and (b) from 20 to 60% by weight, based on the entirety of components (A), (B), and (C), of a copolymer as component (B), obtainable via polymerization of a vinylaromatic monomer and of a vinyl cyanide, and (c) from 20 to 70% by weight, based on the entirety of components (A), (B), and (C), of a graft copolymer as component (C), obtainable from (c1) from 50 to 70% by weight, based on (C), of a core as component (C1), obtainable via polymerization of a 1,3-diene and of a vinylaromatic monomer and an agglomeration polymer, and (c2) from 15 to 25% by weight, based on (C), of a first graft shell as component (C2), obtainable via polymerization of a vinylaromatic monomer, of a C1-C8-alkyl ester of methacrylic acid, and/or of a C1-C8-alkyl ester of acrylic acid, and a crosslinking monomer, and (c3) from 15 to 25% by weight, based on (C), of a second graft shell as component (C3), obtainable via polymerization of a C1-C8-alkyl ester of methacrylic acid as component (C31) and a further monomer as component (C32), where it is essential to the invention that component (C32) is a vinylaromatic monomer and the graft copolymer (C) is produced via emulsion polymerization and is isolated from the reaction mixture by precipitation resulting from shear, and also to processes for producing said molding compositions, to the use of these, and to the moldings obtainable therefrom.
摘要翻译：本发明涉及热塑性模塑组合物，其包含（a）10至50重量％，基于组分（A），（B）和（C）的组分（A），（B）和（C））的混合物，所述甲基丙烯酸甲酯聚合物作为组分 A），（b）20〜60重量％，作为成分（B）的共聚物的组分（A），（B）和（C）的全部，可通过乙烯基芳族单体和（c）20〜70重量％的组分（A），（B）和（C））作为组分（C）的接枝共聚物，可从（ c1）基于（C）50〜70重量％的作为组分（C1）的芯可通过1,3-二烯和乙烯基芳族单体和附聚聚合物的聚合获得，和（c2）从 15重量％至25重量％，基于（C），作为组分（C2）的第一接枝壳可通过乙烯基芳族单体聚合得到甲基丙烯酸的C 1 -C 8烷基酯和/或C 1 -C 8烷基酯丙烯酸的-C8-烷基酯，和a 交联单体和（c3）15至25重量％，基于（C），作为组分（C 3）的第二接枝壳可通过作为组分（C31）的甲基丙烯酸的C 1 -C 8烷基酯的聚合）和作为组分（C32）的另外的单体，其中本发明组分（C32）是乙烯基芳族单体并且通过乳液聚合制备接枝共聚物（C）是重要的，并且通过沉淀从反应混合物中分离剪切，以及用于生产所述模塑组合物的方法，使用它们以及由其获得的模制品。

10. 发明授权

US5698791A Method and device for separating and for measuring the volume of the different phases of a mixture of fluids 失效
标题翻译：用于分离和测量流体混合物的不同相的体积的方法和装置
公开(公告)号：US5698791A
公开(公告)日：1997-12-16
申请号：US575037
申请日：1995-12-19
申请人： Christian Lemaire
发明人： Christian Lemaire
IPC分类号： G01N15/08 , G01N33/24 , G02F1/74
CPC分类号： G01N15/082 , G01N33/241
摘要： Volumes of different constitutive phases of a multiphase mixture contained in a vessel are measured after vertical stratification, mainly by comparing by two differential pressure detectors, the pressure generated by three fluid columns, one being totally filled with at least one of the fluids (a liquid phase for example topped by a gas phase), a second one with at least two of the fluids (one liquid phase for example topped by the same gas phase). The vessel can be, for example, an elongated column with a calibrated section arranged vertically and provided with pressure taps at three distinct points of the height thereof which taps communicate with detectors by appropriate fine lines. A processing set combines the pressure measurements in order to obtain the respective volumes of the phases. This method can be used for volume measurements in various vessels; notably in chemical engineering facilities and to conduct tests on porous geographic samples saturated with a multiphase mixture.
摘要翻译：容器中包含的多相混合物的不同组成相的体积在垂直分层之后测量，主要通过两个差压检测器比较，由三个流体柱产生的压力，一个完全填充有至少一种流体（液体相，例如由气相填充），第二相具有至少两个流体（一个液相例如由相同气相顶部）。容器可以是例如具有校准部分的细长柱，其垂直布置并且在其高度的三个不同点处设置有压力抽头，其中抽头通过适当的细线与检测器通信。处理集合将压力测量结合起来以获得相位的相应体积。该方法可用于各种容器的体积测量; 特别是化学工程设施，并对多相混合物饱和的多孔地质样品进行试验。

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