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1. 发明授权

US07491956B2 Optical scanning device having a distance sensor and a determined focal distance for scanning objects 失效
标题翻译：具有距离传感器和确定的用于扫描物体的焦距的光学扫描装置
公开(公告)号：US07491956B2
公开(公告)日：2009-02-17
申请号：US11699722
申请日：2007-01-29
申请人： Jochem Knoche , Sebastian Schmidt , Christian P. Schultz , Wolfgang Strob
发明人： Jochem Knoche , Sebastian Schmidt , Christian P. Schultz , Wolfgang Strob
IPC分类号： G01N21/86
CPC分类号： G02B27/40 , A61B5/0059 , A61B5/0064
摘要： An optical scanning device is provided. The optical scanning device an excitation light source that is operable to illuminate the object to be scanned. An image detector is operable to detect excited emission rays through illumination of the object to be scanned by the excitation light source and imaging optics that dictate a focal distance. The image detector detects a scan image of the emission radiation of the object to be scanned with the highest level of image sharpness if the focal distance is maintained. A control device includes a distance sensor through which a distance between an optical scanning device and the object to be scanned can be measured, wherein maintenance of the focal distance as the function of the measured distance can be checked by the control device.
摘要翻译：提供光学扫描装置。光学扫描装置可操作以照射被扫描物体的激发光源。图像检测器可操作以通过照射由激发光源和要求焦距的成像光学元件来扫描的物体来检测激发的发射光线。如果保持焦距，图像检测器以最高水平的图像清晰度检测待扫描对象的发射辐射的扫描图像。控制装置包括距离传感器，通过该距离传感器可以测量光学扫描装置与待扫描物体之间的距离，其中通过控制装置可以检测作为测量距离的函数的焦距的维持。

2. 发明申请

US20070239034A1 Optical scanning device 失效
标题翻译：光学扫描装置
公开(公告)号：US20070239034A1
公开(公告)日：2007-10-11
申请号：US11699722
申请日：2007-01-29
申请人： Jochem Knoche , Sebastian Schmidt , Christian Schultz , Wolfgang Strob
发明人： Jochem Knoche , Sebastian Schmidt , Christian Schultz , Wolfgang Strob
IPC分类号： G02B26/08 , A61B6/00
CPC分类号： G02B27/40 , A61B5/0059 , A61B5/0064
摘要： An optical scanning device is provided. The optical scanning device an excitation light source that is operable to illuminate the object to be scanned. An image detector is operable to detect excited emission rays through illumination of the object to be scanned by the excitation light source and imaging optics that dictate a focal distance. The image detector detects a scan image of the emission radiation of the object to be scanned with the highest level of image sharpness if the focal distance is maintained. A control device includes a distance sensor through which a distance between an optical scanning device and the object to be scanned can be measured, wherein maintenance of the focal distance as the function of the measured distance can be checked by the control device.
摘要翻译：提供光学扫描装置。光学扫描装置可操作以照射被扫描物体的激发光源。图像检测器可操作以通过照射由激发光源和要求焦距的成像光学元件来扫描的物体来检测激发的发射光线。如果保持焦距，图像检测器以最高水平的图像清晰度检测待扫描对象的发射辐射的扫描图像。控制装置包括距离传感器，通过该距离传感器可以测量光学扫描装置与待扫描物体之间的距离，其中通过控制装置可以检测作为测量距离的函数的焦距的维持。

3. 发明申请

US20060264761A1 Portable fluorescence scanner for molecular signatures 审中-公开
标题翻译：便携式荧光扫描仪用于分子标记
公开(公告)号：US20060264761A1
公开(公告)日：2006-11-23
申请号：US11375934
申请日：2006-03-15
申请人： Jochem Knoche , Wolfgang Strob
发明人： Jochem Knoche , Wolfgang Strob
IPC分类号： A61B6/00
CPC分类号： A61B5/0059 , A61B5/415 , A61B5/418 , A61B5/7207 , G01N21/6428 , G01N21/6456
摘要： A fluorescence scanner, having a light source for generating excitation light, a detector for detecting fluorescent light, and a data acquisition unit. The excitation light source is operated in pulsed fashion. The pulsed mode results in short exposure times for the fluorescence images, so that artifacts caused by motion are reduced.
摘要翻译：具有用于产生激发光的光源的荧光扫描器，用于检测荧光的检测器和数据获取单元。激发光源以脉冲方式操作。脉冲模式导致荧光图像的短曝光时间，使得由运动引起的伪影减少。

4. 发明授权

US07447538B2 Method and apparatus for displaying a tissue containing a fluorescent dye 有权
标题翻译：用于显示含有荧光染料的组织的方法和装置
公开(公告)号：US07447538B2
公开(公告)日：2008-11-04
申请号：US11525905
申请日：2006-09-25
申请人： Thomas Ehben , Sebastian Schmidt , Wolfgang Strob
发明人： Thomas Ehben , Sebastian Schmidt , Wolfgang Strob
IPC分类号： A61B6/00
CPC分类号： G01N21/6428 , A61B5/0059 , G01N21/3563 , G01N21/359 , G01N21/6456 , G01N2021/6419 , G01N2021/6421 , G01N2201/0691
摘要： A method is disclosed for displaying a tissue containing a fluorescent dye at least in sections. In order to reduce interference signals, it is proposed to record a first fluorescent image during an illumination phase, and a second fluorescent image during a dark phase, and to correct the first fluorescent image by subtracting the second fluorescent image and to process it subsequently to form an overall image.
摘要翻译：公开了至少在部分显示含有荧光染料的组织的方法。为了减少干扰信号，建议在暗相期间在照明阶段记录第一荧光图像和第二荧光图像，并且通过减去第二荧光图像来校正第一荧光图像，并且随后将其处理形成整体形象。

5. 发明申请

US20070083124A1 Method and apparatus for displaying a tissue containing a fluorescent dye 有权
标题翻译：用于显示含有荧光染料的组织的方法和装置
公开(公告)号：US20070083124A1
公开(公告)日：2007-04-12
申请号：US11525905
申请日：2006-09-25
申请人： Thomas Ehben , Sebastian Schmidt , Wolfgang Strob
发明人： Thomas Ehben , Sebastian Schmidt , Wolfgang Strob
IPC分类号： A61B6/00
CPC分类号： G01N21/6428 , A61B5/0059 , G01N21/3563 , G01N21/359 , G01N21/6456 , G01N2021/6419 , G01N2021/6421 , G01N2201/0691
摘要： A method is disclosed for displaying a tissue containing a fluorescent dye at least in sections. In order to reduce interference signals, it is proposed to record a first fluorescent image during an illumination phase, and a second fluorescent image during a dark phase, and to correct the first fluorescent image by subtracting the second fluorescent image and to process it subsequently to form an overall image.
摘要翻译：公开了至少部分显示含有荧光染料的组织的方法。为了减少干扰信号，建议在暗相期间在照明阶段记录第一荧光图像和第二荧光图像，并且通过减去第二荧光图像来校正第一荧光图像，并且随后将其处理形成整体形象。

6. 发明授权

US07633071B2 Image sensor for a fluorescence scanner 失效
标题翻译：用于荧光扫描仪的图像传感器
公开(公告)号：US07633071B2
公开(公告)日：2009-12-15
申请号：US11376583
申请日：2006-03-15
申请人： Norbert Eustergerling , Donal Medlar , Volker Pritsching , Wolfgang Strob
发明人： Norbert Eustergerling , Donal Medlar , Volker Pritsching , Wolfgang Strob
IPC分类号： G02B21/06
CPC分类号： G01N21/645 , A61B1/042 , A61B5/0059 , A61B5/415 , A61B5/418 , G01N21/6486 , H04N5/332
摘要： An image sensor for a fluorescence scanner for recording both optical and fluorescence images is described. The image sensor includes an image detector and a filter layer. The filter layer comprises at least two different surface portions which have at least two different filter properties. At least one surface portion has a filter characteristic such that fluorescent light can pass through, and at least visible light is filtered out. At least one further surface portion has a filter characteristic such that visible light can pass through.
摘要翻译：描述了用于记录光学和荧光图像的荧光扫描仪的图像传感器。图像传感器包括图像检测器和滤波器层。过滤层包括至少两个具有至少两个不同过滤性质的不同表面部分。至少一个表面部分具有使得荧光可以通过的滤光器特性，并且至少可见光被滤出。至少一个另外的表面部分具有使得可见光可以通过的过滤器特性。

7. 发明申请

US20060268402A1 Image sensor for a fluorescence scanner 失效
公开(公告)号：US20060268402A1
公开(公告)日：2006-11-30
申请号：US11376583
申请日：2006-03-15
申请人： Norbert Eustergerling , Donal Medlar , Volker Pritsching , Wolfgang Strob
发明人： Norbert Eustergerling , Donal Medlar , Volker Pritsching , Wolfgang Strob
IPC分类号： G02B21/06
CPC分类号： G01N21/645 , A61B1/042 , A61B5/0059 , A61B5/415 , A61B5/418 , G01N21/6486 , H04N5/332
摘要： An image sensor for a fluorescence scanner for recording both optical and fluorescence images is described. The image sensor includes an image detector and a filter layer. The filter layer comprises at least two different surface portions which have at least two different filter properties. At least one surface portion has a filter characteristic such that fluorescent light can pass through, and at least visible light is filtered out. At least one further surface portion has a filter characteristic such that visible light can pass through.

8. 发明授权

US07750315B2 Apparatus for generating 3D fluorescence or luminescence 失效
标题翻译：用于产生3D荧光或发光的装置
公开(公告)号：US07750315B2
公开(公告)日：2010-07-06
申请号：US11376578
申请日：2006-03-15
申请人： Norbert Eustergerling , Donal Medlar , Volker Pritsching , Wolfgang Strob
发明人： Norbert Eustergerling , Donal Medlar , Volker Pritsching , Wolfgang Strob
IPC分类号： G01N21/64
CPC分类号： G01N21/6456 , A61B5/0059 , A61B5/415 , A61B5/418 , G01N2021/6423 , G06F19/00
摘要： A fluorescence or luminescence scanner and a method for generating 3D fluorescence or luminescence scans are disclosed. The scanner records a fluorescence and/or luminescence image and an optical image of the body to be examined. A pattern, such as a pattern of stripes or some other geometric pattern, is projected at a first angle onto the body to be examined. As a function of the geometric angles, based on the patterns recorded, 3D location information of each surface point of the scanned body is calculated. Both an optical image and a 3D fluorescence and/or luminescence image are obtained. The mutually superimposed (fused) images can be displayed in the form of a 3D fluorescence or luminescence scan.
摘要翻译：公开了荧光或发光扫描器和产生3D荧光或发光扫描的方法。扫描器记录荧光和/或发光图像和待检体的光学图像。将诸如条纹图案或其他几何图案的图案以第一角度投影到要检查的身体上。作为几何角度的函数，基于记录的图案，计算扫描体的每个表面点的3D位置信息。获得光学图像和3D荧光和/或发光图像。相互叠加（融合）的图像可以以3D荧光或发光扫描的形式显示。

9. 发明申请

US20060249690A1 Fluorescence scanner for molecular signatures 失效
公开(公告)号：US20060249690A1
公开(公告)日：2006-11-09
申请号：US11375948
申请日：2006-03-15
申请人： Marcus Pfister , Wolfgang Strob
发明人： Marcus Pfister , Wolfgang Strob
IPC分类号： H05B33/00
CPC分类号： G01N21/6456 , A61B5/0059 , A61B5/415 , A61B5/418 , G01N2201/0221
摘要： An apparatus detects fluorescence. The apparatus, also known as a fluorescence scanner, includes an image detector, which is embodied for detecting image data in the wavelength range of fluorescent light, and an excitation light source, which is embodied for generating light in a wavelength range suitable for exciting the fluorescence. The apparatus has a guide beam projector, which is embodied for generating a guide beam from light in the visible wavelength range. The guide beam is aimed such that a projection of the guide beam, a region that is detectable by the image detector is displayed. The guide beam allows exact viewing of a body region to be examined possible for the surgeon, which is not possible on the basis only of the light for exciting a fluorescence, at least whenever the excitation light is in the non-visible wavelength range, such as IR or NIR, or is generated directly during the recording of the fluorescence image.

10. 发明授权

US5559845A Computed tomography apparatus with a rotating anode x-ray tube and method for operating same 失效
标题翻译：具有旋转阳极x射线管的计算机断层摄影装置及其操作方法
公开(公告)号：US5559845A
公开(公告)日：1996-09-24
申请号：US531278
申请日：1995-09-20
申请人： Wolfgang Strob
发明人： Wolfgang Strob
IPC分类号： H05G1/00 , A61B6/03
CPC分类号： A61B6/035 , A61B6/032
摘要： In a computed tomography apparatus having a gantry, on which a rotating anode x-ray tube and a radiation detector are disposed, the gantry being rotatable around a system axis and being tiltable relative to an axis extending perpendicularly to the system axis, the direction of rotation of the gantry is opposite the direction of rotation of the rotating anode in the x-ray tube. Gyroscopic forces acting on the bearing of the rotating anode are thereby at least partially cancelled, significantly reducing mechanical stress on the anode bearing.
摘要翻译：在具有台架的计算机断层摄影装置中，旋转阳极x射线管和放射线检测器设置在该台架上，所述台架能够围绕系统轴线旋转并且可相对于垂直于系统轴延伸的轴线倾斜，台架的旋转与X射线管中的旋转阳极的旋转方向相反。因此，作用在旋转阳极的轴承上的陀螺力因此被至少部分抵消，显着地降低了阳极轴承上的机械应力。

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