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1. 发明授权

US07954492B2 Pharmaceutical powder cartridge, and inhaler equipped with same 有权
标题翻译：制药粉盒和配备相同的吸入器
公开(公告)号：US07954492B2
公开(公告)日：2011-06-07
申请号：US11270678
申请日：2005-11-09
申请人： Joachim Goede , Martin Herder , Karl-Heinz Lange , Meike Eilbracht
发明人： Joachim Goede , Martin Herder , Karl-Heinz Lange , Meike Eilbracht
IPC分类号： A61M15/00 , A61M16/00
CPC分类号： A61M15/0065 , A61M15/0003 , A61M2202/064
摘要： To improve administration of powdered pharmaceuticals, a pharmaceutical powder cartridge (1) for powder inhalers for holding a pharmaceutical depot for a large number of pharmaceutical powder doses is proposed, having at least one storage space (6) and an integrated metering device, said integrated metering device comprising at least one metering slide (9, 13, 14) which can be moved approximately transversely in a metering slide channel (12) at least from a filling position to an emptying position, approximately transversely with respect to the direction of flow of the pharmaceutical powder out from the at least one storage space (6), said metering slide channel (12) with the at least one metering slide (9, 13, 14) being sealed off from the environment at least in the filling position of the metering slide (9, 13, 14), and also further measures and a corresponding inhaler.
摘要翻译：为了改善粉末药物的给药，提出了一种用于容纳大量药物粉末剂量的药物贮库的用于粉末吸入器的药物粉盒（1），其具有至少一个储存空间（6）和一体式计量装置计量装置包括至少一个计量滑动件（9,13,14），其可以在计量滑动通道（12）中大致横向移动至少从填充位置到排空位置，大致横向于相对于流动方向的流动方向所述药物粉末从所述至少一个存储空间（6）出来，所述计量滑动通道（12）与所述至少一个计量滑动件（9,13,14）至少在所述至少一个计量滑动件计量滑块（9,13,14），以及进一步措施和相应的吸入器。

2. 发明授权

US07234464B2 Storage system for powdered pharmaceuticals, and inhaler equipped with this system 有权
标题翻译：粉末药品储存系统和配有该系统的吸入器
公开(公告)号：US07234464B2
公开(公告)日：2007-06-26
申请号：US09739170
申请日：2000-12-18
申请人： Joachim Goede , Karl-Heinz Lange
发明人： Joachim Goede , Karl-Heinz Lange
IPC分类号： A61M15/00
CPC分类号： A61M15/0003 , A61M15/0066 , A61M2202/064
摘要： A cartridge for powdered pharmaceuticals. At least two storage spaces are provided which are separate from each other and which are each intended to hold a multiplicity of doses of a medically active substance. The storage spaces are individual cartridges which may be lockingly coupled together to form a single cartridge. Each individual cartridge has a metering cavity.
摘要翻译：用于粉末药物的药筒。提供至少两个彼此分离的储存空间，它们各自用于容纳多种剂量的医用活性物质。存储空间是可以锁定地联接在一起以形成单个盒的各个盒。每个单独的墨盒具有计量腔。

3. 发明授权

US07258118B2 Pharmaceutical powder cartridge, and inhaler equipped with same 有权
标题翻译：制药粉盒和配备相同的吸入器
公开(公告)号：US07258118B2
公开(公告)日：2007-08-21
申请号：US10348874
申请日：2003-01-22
申请人： Joachim Goede , Martin Herder , Karl-Heinz Lange , Meike Eilbracht
发明人： Joachim Goede , Martin Herder , Karl-Heinz Lange , Meike Eilbracht
IPC分类号： A61M15/00 , A61M16/00
CPC分类号： A61M15/0065 , A61M15/0003 , A61M2202/064
摘要： To improve administration of powdered pharmaceuticals, a pharmaceutical powder cartridge (1) for powder inhalers for holding a pharmaceutical depot for a large number of pharmaceutical powder doses is proposed, having at least one storage space (6) and an integrated metering device, said integrated metering device comprising at least one metering slide (9, 13, 14) which can be moved approximately transversely in a metering slide channel (12) at least from a filling position to an emptying position, approximately transversely with respect to the direction of flow of the pharmaceutical powder out from the at least one storage space (6), said metering slide channel (12) with the at least one metering slide (9, 13, 14) being sealed off from the environment at least in the filling position of the metering slide (9, 13, 14), and also further measures and a corresponding inhaler.
摘要翻译：为了改善粉末药物的给药，提出了一种用于容纳大量药物粉末剂量的药物贮库的用于粉末吸入器的药物粉盒（1），其具有至少一个储存空间（6）和一体式计量装置计量装置包括至少一个计量滑动件（9,13,14），其可以在计量滑动通道（12）中大致横向移动至少从填充位置到排空位置，大致横向于相对于流动方向的流动方向所述药物粉末从所述至少一个存储空间（6）出来，所述计量滑动通道（12）与所述至少一个计量滑动件（9,13,14）至少在所述至少一个计量滑动件计量滑块（9,13,14），以及进一步措施和相应的吸入器。

4. 发明申请

US20060081246A1 Pharmaceutical powder cartridge, and inhaler equipped with same 有权
标题翻译：制药粉盒和配备相同的吸入器
公开(公告)号：US20060081246A1
公开(公告)日：2006-04-20
申请号：US11270678
申请日：2005-11-09
申请人： Joachim Goede , Martin Herder , Karl-Heinz Lange , Meike Eilbracht
发明人： Joachim Goede , Martin Herder , Karl-Heinz Lange , Meike Eilbracht
IPC分类号： A61M15/00
CPC分类号： A61M15/0065 , A61M15/0003 , A61M2202/064
摘要： To improve administration of powdered pharmaceuticals, a pharmaceutical powder cartridge (1) for powder inhalers for holding a pharmaceutical depot for a large number of pharmaceutical powder doses is proposed, having at least one storage space (6) and an integrated metering device, said integrated metering device comprising at least one metering slide (9, 13, 14) which can be moved approximately transversely in a metering slide channel (12) at least from a filling position to an emptying position, approximately transversely with respect to the direction of flow of the pharmaceutical powder out from the at least one storage space (6), said metering slide channel (12) with the at least one metering slide (9, 13, 14) being sealed off from the environment at least in the filling position of the metering slide (9, 13, 14), and also further measures and a corresponding inhaler.
摘要翻译：为了改善粉末药物的给药，提出了一种用于容纳大量药物粉末剂量的药物贮库的用于粉末吸入器的药物粉盒（1），其具有至少一个储存空间（6）和一体式计量装置计量装置包括至少一个计量滑动件（9,13,14），其可以在计量滑动通道（12）中大致横向移动至少从填充位置到排空位置，大致横向于相对于流动方向的流动方向所述药物粉末从所述至少一个存储空间（6）出来，所述计量滑动通道（12）与所述至少一个计量滑动件（9,13,14）至少在所述至少一个计量滑动件计量滑块（9,13,14），以及进一步措施和相应的吸入器。

5. 发明授权

US08375940B2 Storage system for powdered pharmaceuticals and inhaler equipped with this system 有权
标题翻译：配有该系统的粉末药物和吸入器的储存系统
公开(公告)号：US08375940B2
公开(公告)日：2013-02-19
申请号：US11753681
申请日：2007-05-25
申请人： Joachim Goede , Karl-Heinz Lange
发明人： Joachim Goede , Karl-Heinz Lange
IPC分类号： A61M15/00
CPC分类号： A61M15/0003 , A61M15/0066 , A61M2202/064
摘要： In order to improve the administration of powdered pharmaceuticals, the invention proposes a storage system for powdered pharmaceuticals, in particular for use or integration in a powder inhaler, for receiving a multiplicity of doses of at least one medically active substance, with at least two storage spaces (4) which are separate from each other and are each intended to hold a multiplicity of doses of a medically active substance, and the invention also proposes an inhaler for powdered pharmaceuticals, the inhaler comprising such a pharmaceutical powder cartridge system (1) as an integral part or as an exchangeable part.
摘要翻译：为了改进粉状药物的给药，本发明提出了一种用于粉末状药物的储存系统，特别是用于或整合在粉末吸入器中，用于接收多种剂量的至少一种医用活性物质，其中至少两个储存空间（4）彼此分开并且各自用于容纳多种剂量的医疗活性物质，并且本发明还提出了一种用于粉末状药物的吸入器，该吸入器包括这样的药物粉末盒系统（1），如组成部分或可交换部分。

6. 发明申请

US20070215152A1 STORAGE SYSTEM FOR POWDERED PHARMACEUTICALS AND INHALER EQUIPPED WITH THIS SYTEM 有权
标题翻译：粉末制药储存系统和装有本SYIS的吸入器
公开(公告)号：US20070215152A1
公开(公告)日：2007-09-20
申请号：US11753681
申请日：2007-05-25
申请人： Joachim Goede , Karl-Heinz Lange
发明人： Joachim Goede , Karl-Heinz Lange
IPC分类号： A61M15/00 , B65D83/04
CPC分类号： A61M15/0003 , A61M15/0066 , A61M2202/064
摘要： In order to improve the administration of powdered pharmaceuticals, the invention proposes a storage system for powdered pharmaceuticals, in particular for use or integration in a powder inhaler, for receiving a multiplicity of doses of at least one medically active substance, with at least two storage spaces (4) which are separate from each other and are each intended to hold a multiplicity of doses of a medically active substance, and the invention also proposes an inhaler for powdered pharmaceuticals, the inhaler comprising such a pharmaceutical powder cartridge system (1) as an integral part or as an exchangeable part.
摘要翻译：为了改进粉状药物的给药，本发明提出了一种用于粉末状药物的储存系统，特别是用于或整合在粉末吸入器中，用于接收多种剂量的至少一种医用活性物质，其中至少两个储存空间（4）彼此分开并且各自用于容纳多种剂量的医疗活性物质，并且本发明还提出了一种用于粉末状药物的吸入器，该吸入器包括这样的药物粉末盒系统（1），如组成部分或可交换部分。

7. 发明授权

US06667058B1 Oral forms of administration containing solid flupirtine with controlled release of active substance 失效
标题翻译：含有活性物质控制释放的固体氟吡汀的口服形式的给药
公开(公告)号：US06667058B1
公开(公告)日：2003-12-23
申请号：US08212578
申请日：1994-03-17
申请人： Joachim Goede , Helmut Hettche , Helmut Momberger , Jürgen Engel , Michael Lobisch
发明人： Joachim Goede , Helmut Hettche , Helmut Momberger , Jürgen Engel , Michael Lobisch
IPC分类号： A61K908
CPC分类号： A61K31/44 , A61K9/2077 , A61K9/209 , A61K9/5078 , A61K9/5084
摘要： Pharmaceutical dosage units containing flupirtine or a pharmaceutically acceptable salt of flupirtine with controlled release of active substance using a delayed-action or controlled-release component. There are 0.001 to 20 parts delayed-action component for each part by weight flupirtine (calculated as the base) and the release rate of flupirtine is between 5 and 300 mg per hour. In some cases, the dosage units may also contain a rapidly releasing component of flupirtine or of one of its salts. The dosage units reduce the sedative effect of flupirtine.
摘要翻译：含有氟吡汀或氟吡汀药学上可接受的盐的药物剂量单位，其使用延迟作用或控制释放组分控制释放活性物质。对于每份重量的氟吡汀（以碱为基准计），有0.001-20份延迟作用组分，氟吡汀的释放速率为5至300mg /小时。在一些情况下，剂量单位还可以含有氟吡汀或其一种盐的快速释放组分。剂量单位降低氟吡汀的镇静作用。

8. 发明授权

US5840279A Pharmaceutical powder cartridge with integrated metering device and inhaler for powdered medicaments 失效
标题翻译：具有集成计量装置和粉末药物吸入器的药粉盒
公开(公告)号：US5840279A
公开(公告)日：1998-11-24
申请号：US667414
申请日：1996-06-21
申请人： Andre Narodylo , Wolfgang Gottenauer , Joachim Goede , Coenraad Lerk , Anne H. De Boer
发明人： Andre Narodylo , Wolfgang Gottenauer , Joachim Goede , Coenraad Lerk , Anne H. De Boer
IPC分类号： A61K9/14 , A61K9/72 , A61M11/00 , A61M15/00
CPC分类号： A61M15/00 , A61M11/002 , A61M15/0065 , A61M15/0068 , A61M15/0095 , A61M15/0096 , A61M2202/064
摘要： Pharmaceutical powder cartridge for powder inhalers for receiving a medicament depot for a large number of pharmaceutical powder doses, having an integrated metering device which comprises at least one metering cavity for receiving a predetermined quantity of a pharmaceutical powder, the integrated metering device being capable of being moved at least out of a filling position into an emptying position approximately transversely with respect to the flow direction of the pharmaceutical powder, and an inhaler for powdered medicaments, in which inhaler the medicament can be received by a patient by means of an air stream and which has a receptacle for such a pharmaceutical powder cartridge.
摘要翻译：用于接收用于大量药物粉末剂量的药物贮库的粉末吸入器的药物粉末盒，其具有集成的计量装置，其包括用于接收预定量的药物粉末的至少一个计量腔，所述综合计量装置能够至少从填充位置移动到相对于药物粉末的流动方向大致横向的排空位置，以及用于粉末状药物的吸入器，其中药物可以由患者通过气流接收，并且其具有用于这种药物粉末盒的容器。

9. 发明授权

US10537550B2 Methods of treating underlying inflammation from COPD or asthma 有权
公开(公告)号：US10537550B2
公开(公告)日：2020-01-21
申请号：US12189598
申请日：2008-08-11
申请人： Joachim Goede , Joachim Maus , Peter Jürgen Cnota , Istvan Szelenyi
发明人： Joachim Goede , Joachim Maus , Peter Jürgen Cnota , Istvan Szelenyi
IPC分类号： A61K31/401 , A61K31/4015 , A61K31/573
摘要： The present invention describes the combination of topically inhaled medicinal formulations comprising an anticholinergic component and a glucocorticosteroid component and its use in the symptomatic and prophylactic treatment of diseases of the respiratory tract, especially with an obstructive component or underlying inflammation like asthma and chronic obstructive pulmonary disease (COPD). It further comprises the presentation of this combination in a locally applied (inhaled) formulation and application in an inhalation device for instance in the NOVOLIZER®.

10. 发明授权

US07985766B2 Combination of anticholineric and β mimetics for the treatment of respiratory diseases 有权
标题翻译：抗胆碱药与组合用于治疗呼吸系统疾病的模拟物质
公开(公告)号：US07985766B2
公开(公告)日：2011-07-26
申请号：US11882109
申请日：2007-07-30
申请人： Joachim Goede , Joachim Maus , Peter Jurgen Cnota , Istvan Szelenyi
发明人： Joachim Goede , Joachim Maus , Peter Jurgen Cnota , Istvan Szelenyi
IPC分类号： A61K31/4015 , A61K31/167
CPC分类号： A61K45/06 , A61K9/0075 , A61K9/008 , A61K31/138 , A61K31/167 , A61K31/401 , A61K31/4015 , A61K2300/00
摘要： The present invention describes a combination of an anticholinergic, such as R,R-glycopyrrolate, and a β mimetic, such as tormoterol, for the treatment of respiratory diseases including airway inflammation or obstruction such as chronic obstructive pulmonary disease (COPD) and asthma.
摘要翻译：本发明描述了抗胆碱能药物如R，R-格隆溴铵和一种bgr的组合; 模拟物，如泰莫曲醇，用于治疗呼吸道疾病，包括呼吸道炎症或梗阻，如慢性阻塞性肺疾病（COPD）和哮喘。

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