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1. 发明申请

US20050014705A1 Coumarin derivatives useful as tnf alpha inhibitors 有权
标题翻译：香豆素衍生物可用作tnfα抑制剂
公开(公告)号：US20050014705A1
公开(公告)日：2005-01-20
申请号：US10333366
申请日：2001-07-19
申请人： Jie Cheng , Thomas Arrhenius , David Wallace , Mi Chen , Sovouthy Tith , Yoshiyuki Ono , Yoshiaki Watanabe
发明人： Jie Cheng , Thomas Arrhenius , David Wallace , Mi Chen , Sovouthy Tith , Yoshiyuki Ono , Yoshiaki Watanabe
IPC分类号： A61K31/37 , A61K31/381 , A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/422 , A61K31/427 , A61K31/4433 , A61K31/453 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/7048 , A61P1/04 , A61P3/10 , A61P7/00 , A61P9/10 , A61P11/02 , A61P11/06 , A61P11/16 , A61P17/06 , A61P19/02 , A61P19/08 , A61P19/10 , A61P21/00 , A61P25/00 , A61P25/18 , A61P27/02 , A61P29/00 , A61P29/02 , A61P31/04 , A61P33/06 , A61P35/00 , A61P37/02 , A61P37/06 , A61P39/02 , A61P43/00 , C07D311/16 , C07D311/18 , C07D405/04 , C07D405/06 , C07D405/12 , C07D405/14 , C07D407/06 , C07D409/06 , C07D417/06 , C07D417/12 , A61K31/353
CPC分类号： A61K31/37 , A61K31/4025 , A61K31/4178 , A61K31/422 , A61K31/427 , A61K31/453 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/7048 , C07D311/16 , C07D405/04 , C07D405/06 , C07D405/12 , C07D405/14 , Y02A50/411
摘要： Novel compounds composition capable of inhibiting TNFα and having antiimmunoinflammatory and autoimmune properties useful in a pharmaceutical composition, such as for a drug containing this as an active ingredient; and a therapeutic method with the use of these novel compounds.
摘要翻译：能够抑制TNFα并具有用于药物组合物的抗免疫炎性和自身免疫性质的新型化合物组合物，例如含有该作为活性成分的药物; 以及使用这些新化合物的治疗方法。

2. 发明申请

US20060020138A1 Coumarin derivatives useful as TNFalpha inhibitors 有权
标题翻译：可用作TNFα抑制剂的香豆素衍生物
公开(公告)号：US20060020138A1
公开(公告)日：2006-01-26
申请号：US11225940
申请日：2005-09-13
申请人： Jie Cheng , Thomas Arrhenius , David Wallace , Mi Chen , Sovouthy Tith , Hirotaka Kashiwagi , Yoshiyuki Ono , Yoshiaki Watanabe
发明人： Jie Cheng , Thomas Arrhenius , David Wallace , Mi Chen , Sovouthy Tith , Hirotaka Kashiwagi , Yoshiyuki Ono , Yoshiaki Watanabe
IPC分类号： A61K31/366 , C07D311/06
CPC分类号： A61K31/37 , A61K31/4025 , A61K31/4178 , A61K31/422 , A61K31/427 , A61K31/453 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/7048 , C07D311/16 , C07D405/04 , C07D405/06 , C07D405/12 , C07D405/14 , Y02A50/411
摘要： Novel compounds composition capable of inhibiting TNFα and having anti immunoinflammatory and autoimmune properties useful in a pharmaceutical composition, such as for a drug containing this as an active ingredient; and a therapeutic method with the use of these novel compounds.
摘要翻译：能够抑制TNFα并具有用于药物组合物的抗免疫炎症和自身免疫性质的新型化合物组合物，例如含有该作为活性成分的药物; 以及使用这些新化合物的治疗方法。

3. 发明授权

US07994318B2 Coumarin derivatives useful as TNFα inhibitors 有权
标题翻译：香豆素衍生物可用作TNFα抑制剂
公开(公告)号：US07994318B2
公开(公告)日：2011-08-09
申请号：US12727053
申请日：2010-03-18
申请人： Jie Fei Cheng , Thomas Arrhenius , David Wallace , Mi Chen , Sovouthy Tith , Hirotaka Kashiwagi , Yoshiyuki Ono , Yoshiaki Watanabe
发明人： Jie Fei Cheng , Thomas Arrhenius , David Wallace , Mi Chen , Sovouthy Tith , Hirotaka Kashiwagi , Yoshiyuki Ono , Yoshiaki Watanabe
IPC分类号： C07D239/32 , C07D401/16 , C07D417/14
CPC分类号： A61K31/37 , A61K31/4025 , A61K31/4178 , A61K31/422 , A61K31/427 , A61K31/453 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/7048 , C07D311/16 , C07D405/04 , C07D405/06 , C07D405/12 , C07D405/14 , Y02A50/411
摘要： Novel compounds composition capable of inhibiting TNFα and having antiimmunionflammatory and autoimmune properties useful in a pharmaceutical composition, such as for a drug containing this as an active ingredient; and a therapeutic method with the use of these novel compounds.
摘要翻译：能够抑制TNFα并具有用于药物组合物的抗免疫性炎症和自身免疫性质的新型化合物组合物，例如含有其作为活性成分的药物; 以及使用这些新化合物的治疗方法。

4. 发明申请

US20100197917A1 COUMARIN DERIVATIVES USEFUL AS TNF ALPHA INHIBITORS 有权
公开(公告)号：US20100197917A1
公开(公告)日：2010-08-05
申请号：US12727053
申请日：2010-03-18
申请人： Jie Fei Cheng , Thomas Arrhenius , David Wallace , Mi Chen , Sovouthy Tith , Hirotaka Kashiwagi , Yoshiyuki Ono , Yoshiaki Watanabe
发明人： Jie Fei Cheng , Thomas Arrhenius , David Wallace , Mi Chen , Sovouthy Tith , Hirotaka Kashiwagi , Yoshiyuki Ono , Yoshiaki Watanabe
IPC分类号： C07D239/10 , C07D311/06 , C07D405/12 , C07D277/20
CPC分类号： A61K31/37 , A61K31/4025 , A61K31/4178 , A61K31/422 , A61K31/427 , A61K31/453 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/7048 , C07D311/16 , C07D405/04 , C07D405/06 , C07D405/12 , C07D405/14 , Y02A50/411
摘要： Novel compounds composition capable of inhibiting TNFα and having antiimmunionflammatory and autoimmune properties useful in a pharmaceutical composition, such as for a drug containing this as an active ingredient; and a therapeutic method with the use of these novel compounds.

5. 发明授权

US07872142B2 Coumarin derivatives useful as TNFα inhibitors 有权
标题翻译：香豆素衍生物可用作TNFα抑制剂
公开(公告)号：US07872142B2
公开(公告)日：2011-01-18
申请号：US12726986
申请日：2010-03-18
申请人： Jie Fei Cheng , Thomas Arrhenius , David Wallace , Mi Chen , Sovouthy Tith , Hirotaka Kashiwagi , Yoshiyuki Ono , Yoshiaki Watanabe
发明人： Jie Fei Cheng , Thomas Arrhenius , David Wallace , Mi Chen , Sovouthy Tith , Hirotaka Kashiwagi , Yoshiyuki Ono , Yoshiaki Watanabe
IPC分类号： C07D405/06
CPC分类号： A61K31/37 , A61K31/4025 , A61K31/4178 , A61K31/422 , A61K31/427 , A61K31/453 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/7048 , C07D311/16 , C07D405/04 , C07D405/06 , C07D405/12 , C07D405/14 , Y02A50/411
摘要： Novel compounds composition capable of inhibiting TNFα and having antiimmunoinflammatory and autoimmune properties useful in a pharmaceutical composition, such as for a drug containing this as an active ingredient; and a therapeutic method with the use of these novel compounds.
摘要翻译：能够抑制TNFα并具有用于药物组合物的抗免疫炎症和自身免疫性质的新型化合物组合物，例如含有其作为活性成分的药物; 以及使用这些新化合物的治疗方法。

6. 发明申请

US20100174076A1 COUMARIN DERIVATIVES USEFUL AS TNF ALPHA INHIBITORS 有权
标题翻译：作为TNF ALPHA抑制剂有用的COUMARIN衍生物
公开(公告)号：US20100174076A1
公开(公告)日：2010-07-08
申请号：US12726986
申请日：2010-03-18
申请人： Jie Fei Cheng , Thomas Arrhenius , David Wallace , Mi Chen , Sovouthy Tith , Hirotaka Kashiwagi , Yoshiyuki Ono , Yoshiaki Watanabe
发明人： Jie Fei Cheng , Thomas Arrhenius , David Wallace , Mi Chen , Sovouthy Tith , Hirotaka Kashiwagi , Yoshiyuki Ono , Yoshiaki Watanabe
IPC分类号： C07D239/28 , C07D311/04 , C07D405/10 , C07D239/02
CPC分类号： A61K31/37 , A61K31/4025 , A61K31/4178 , A61K31/422 , A61K31/427 , A61K31/453 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/7048 , C07D311/16 , C07D405/04 , C07D405/06 , C07D405/12 , C07D405/14 , Y02A50/411
摘要： Novel compounds composition capable of inhibiting TNFα and having antiimmunionflammatory and autoimmune properties useful in a pharmaceutical composition, such as for a drug containing this as an active ingredient; and a therapeutic method with the use of these novel compounds.
摘要翻译：能够抑制TNFα并具有用于药物组合物的抗免疫性炎症和自身免疫性质的新型化合物组合物，例如含有其作为活性成分的药物; 以及使用这些新化合物的治疗方法。

7. 发明授权

US07709664B2 Coumarin derivatives useful as TNFα inhibitors 有权
标题翻译：香豆素衍生物可用作TNFα抑制剂
公开(公告)号：US07709664B2
公开(公告)日：2010-05-04
申请号：US11225940
申请日：2005-09-13
申请人： Jie Fei Cheng , Thomas Arrhenius , David Wallace , Mi Chen , Sovouthy Tith , Hirotaka Kashiwagi , Yoshiyuki Ono , Yoshiaki Watanabe
发明人： Jie Fei Cheng , Thomas Arrhenius , David Wallace , Mi Chen , Sovouthy Tith , Hirotaka Kashiwagi , Yoshiyuki Ono , Yoshiaki Watanabe
IPC分类号： C07D311/12
CPC分类号： A61K31/37 , A61K31/4025 , A61K31/4178 , A61K31/422 , A61K31/427 , A61K31/453 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/7048 , C07D311/16 , C07D405/04 , C07D405/06 , C07D405/12 , C07D405/14 , Y02A50/411
摘要： Novel compounds composition capable of inhibiting TNFα and having anti immunoinflammatory and autoimmune properties useful in a pharmaceutical composition, such as for a drug containing this as an active ingredient; and a therapeutic method with the use of these novel compounds.
摘要翻译：能够抑制TNFα并具有用于药物组合物的抗免疫炎症和自身免疫性质的新型化合物组合物，例如含有该作为活性成分的药物; 以及使用这些新化合物的治疗方法。

8. 发明授权

US07026491B2 Coumarin derivatives useful as TNFα inhibitors 有权
标题翻译：可用作TNFα抑制剂的香豆素衍生物
公开(公告)号：US07026491B2
公开(公告)日：2006-04-11
申请号：US10333366
申请日：2001-07-19
申请人： Jie Fei Cheng , Hirotaka Kashiwagi , Thomas Arrhenius , David Wallace , Mi Chen , Sovouthy Tith , Yoshiyuki Ono , Yoshiaki Watanabe
发明人： Jie Fei Cheng , Hirotaka Kashiwagi , Thomas Arrhenius , David Wallace , Mi Chen , Sovouthy Tith , Yoshiyuki Ono , Yoshiaki Watanabe
IPC分类号： C07D405/12 , C07D407/12 , C07D311/12
CPC分类号： A61K31/37 , A61K31/4025 , A61K31/4178 , A61K31/422 , A61K31/427 , A61K31/453 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/7048 , C07D311/16 , C07D405/04 , C07D405/06 , C07D405/12 , C07D405/14 , Y02A50/411
摘要： Novel compounds composition capable of inhibiting TNFα and having antiimmunoinflammatory and autoimmune properties useful in a pharmaceutical composition, such as for a drug containing this as an active ingredient; and a therapeutic method with the use of these novel compounds.
摘要翻译：能够抑制TNFα并具有用于药物组合物的抗免疫炎性和自身免疫性质的新型化合物组合物，例如含有该作为活性成分的药物; 以及使用这些新化合物的治疗方法。

9. 发明申请

US20060025474A1 Bisphenyl compounds useful as vitamin D3 receptor agonists 审中-公开
标题翻译：可用作维生素D3受体激动剂的二苯基化合物
公开(公告)号：US20060025474A1
公开(公告)日：2006-02-02
申请号：US11076584
申请日：2005-03-08
申请人： David Wallace , Thomas Arrhenius , Anna Russell , Dingguo Liu , Amy Xing , Sovouthy Tith , Zheng Hou , Tadakatsu Takahashi , Yoshiyuki Ono , Hirotaka Kashiwagi , Kazuki Shimizu , Hitoshi Ikura
发明人： David Wallace , Thomas Arrhenius , Anna Russell , Dingguo Liu , Amy Xing , Sovouthy Tith , Zheng Hou , Tadakatsu Takahashi , Yoshiyuki Ono , Hirotaka Kashiwagi , Kazuki Shimizu , Hitoshi Ikura
IPC分类号： A61K31/366 , A61K31/365 , A61K31/192
CPC分类号： C07D207/26 , C07C57/60 , C07C59/56 , C07C59/68 , C07C59/72 , C07C65/28 , C07C69/712 , C07C69/732 , C07C217/20 , C07C217/34 , C07C229/22 , C07C233/25 , C07C235/20 , C07C317/18 , C07C317/44 , C07C323/16 , C07C2601/08 , C07C2601/14 , C07D205/08 , C07D207/16 , C07D209/32 , C07D211/40 , C07D213/30 , C07D257/04 , C07D307/12 , C07D307/32 , C07D307/33 , C07D307/68 , C07D309/22 , C07D309/30 , C07D317/22 , C07D319/12
摘要： The present invention discloses bisphenyl compounds of the formula: wherein R1, R2, R3, R4, R5, R6, X, Y, W are defined herein after. These compounds are useful as pharmaceuticals.
摘要翻译：本发明公开了下式的双苯化合物：其中R 1，R 2，R 3，R 4，R 5，R 6，X，Y，W如下文所定义。这些化合物可用作药物。

10. 发明授权

US08873475B2 Method of controlling allocation of a radio resource for transmitting a radio resource allocation request 有权
标题翻译：控制用于发送无线资源分配请求的无线资源的分配的方法
公开(公告)号：US08873475B2
公开(公告)日：2014-10-28
申请号：US12612893
申请日：2009-11-05
申请人： Yoshiyuki Ono
发明人： Yoshiyuki Ono
IPC分类号： H04W4/00 , H04W72/12 , H04L12/28 , H04J3/00 , H04L12/66 , H04W72/00 , H04W72/04 , H04W8/24
CPC分类号： H04W72/1252 , H04W8/24 , H04W72/0413 , H04W72/042 , H04W72/1242 , H04W72/1284
摘要： Provided is a allocation controlling method of a radio resource for a radio resource allocation request in a base station which allocates, to a terminal, in response to the radio resource allocation request received from the terminal, a radio resource for transmitting retention data in a transmission buffer of the terminal to the base station, and which transmits to the terminal a radio resource allocation notification indicating a result of the allocation. When an amount of retention data in the transmission buffer received from the terminal is not zero, a transmission cycle that is suited to the retention amount is determined as a transmission cycle of the notification of radio resource allocation for transmitting the retention data in the transmission buffer and, during cyclic transmission of the radio resource allocation notification, the allocation of a radio resource for the radio resource allocation request is stopped.
摘要翻译：提供了一种用于基站中的无线电资源分配请求的无线电资源的分配控制方法，该基站响应于从终端接收到的无线电资源分配请求向终端分配用于在传输中发送保留数据的无线电资源向基站发送终端的缓冲器，向终端发送表示分配结果的无线资源分配通知。当从终端接收到的发送缓冲器中的保留数据量不为零时，将适合于保留量的发送周期确定为用于在发送缓冲器中发送保留数据的无线资源分配通知的发送周期并且在循环发送无线资源分配通知期间，停止对无线资源分配请求的无线资源的分配。

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