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1. 发明申请

US20090068739A1 Cell culture scaffold, methods of manufacturing the scaffold and cell culture methods 失效
标题翻译：细胞培养支架，制造支架的方法和细胞培养方法
公开(公告)号：US20090068739A1
公开(公告)日：2009-03-12
申请号：US12230457
申请日：2008-08-29
申请人： Jian Ping Gong , Yoshihito Osada , Yongmei Chen
发明人： Jian Ping Gong , Yoshihito Osada , Yongmei Chen
IPC分类号： C12N5/06
CPC分类号： C12N5/0068 , C12M25/14 , C12N2533/30
摘要： A cell culture scaffold containing a gel having a network structure comprised of a synthetic polymer such that cultured cells spread in a shorter time and the number of adsorbed cultured cells per unit area is larger than in the case of using a gel having a network structure comprised of polyacrylic acid, while taking advantage of synthetic polymers with low manufacturing cost, easy quality control and no risk of virus infection in cultured cell. Used as the cell culture scaffold is a gel containing a synthetic polymer obtained by polymerization or copolymerization of a monomer having a sulfonic group such as p-styrenesulfonic acid sodium salt (NaSS) and 2-acrylamide-2-methylpropane sulfonic acid sodium salt (NaAMPS).
摘要翻译：一种细胞培养支架，其含有具有由合成聚合物组成的网状结构的凝胶，使得培养细胞在较短时间内扩散，每单位面积吸附培养细胞数量大于使用具有网状结构的凝胶的情况的聚丙烯酸，同时利用低制造成本的合成聚合物，容易的质量控制和培养细胞中没有病毒感染的风险。用作细胞培养支架是含有通过聚合或共聚具有磺酸基的单体如对苯乙烯磺酸钠盐（NaSS）和2-丙烯酰胺-2-甲基丙磺酸钠盐（NaAMPS ）。

2. 发明授权

US07435594B2 Scaffold for culturing cells 失效
标题翻译：用于培养细胞的支架
公开(公告)号：US07435594B2
公开(公告)日：2008-10-14
申请号：US11050426
申请日：2005-02-04
申请人： Jian Ping Gong , Yoshihito Osada , Yongmei Chen
发明人： Jian Ping Gong , Yoshihito Osada , Yongmei Chen
IPC分类号： C12N5/00 , C12N11/08
CPC分类号： C12N5/0068 , C12M25/14 , C12N2533/30
摘要： A cell culture scaffold containing a gel having a network structure comprised of a synthetic polymer such that cultured cells spread in a shorter time and the number of adsorbed cultured cells per unit area is larger than in the case of using a gel having a network structure comprised of polyacrylic acid, while taking advantage of synthetic polymers with low manufacturing cost, easy quality control and no risk of virus infection in cultured cell. Used as the cell culture scaffold is a gel containing asynthetic polymer obtained by polymerization or copolymerization of a monomer having a sulfonic group such as p-styrenesulfonic acid sodium salt (NaSS) and 2-acrylamide-2-methylpropane sulfonic acid sodium salt (NaAMPS).
摘要翻译：一种细胞培养支架，其含有具有由合成聚合物组成的网状结构的凝胶，使得培养细胞在较短时间内扩散，每单位面积吸附培养细胞数量大于使用具有网状结构的凝胶的情况的聚丙烯酸，同时利用低制造成本的合成聚合物，容易的质量控制和培养细胞中没有病毒感染的风险。用作细胞培养支架是含有通过聚合或共聚具有磺酸基的单体如对苯乙烯磺酸钠盐（NaSS）和2-丙烯酰胺-2-甲基丙磺酸钠盐（NaAMPS）得到的合成聚合物的凝胶，。

3. 发明授权

US08158425B2 Cell culture scaffold containing gel having interpenetrating polymer network structure 失效
标题翻译：含有互穿聚合物网络结构的凝胶的细胞培养支架
公开(公告)号：US08158425B2
公开(公告)日：2012-04-17
申请号：US12230457
申请日：2008-08-29
申请人： Jian Ping Gong , Yoshihito Osada , Yongmei Chen
发明人： Jian Ping Gong , Yoshihito Osada , Yongmei Chen
IPC分类号： C12N5/00 , C12N5/07 , C12N11/08
CPC分类号： C12N5/0068 , C12M25/14 , C12N2533/30
摘要： A cell culture scaffold containing a gel having a network structure comprised of a synthetic polymer such that cultured cells spread in a shorter time and the number of adsorbed cultured cells per unit area is larger than in the case of using a gel having a network structure comprised of polyacrylic acid, while taking advantage of synthetic polymers with low manufacturing cost, easy quality control and no risk of virus infection in cultured cell. Used as the cell culture scaffold is a gel containing a synthetic polymer obtained by polymerization or copolymerization of a monomer having a sulfonic group such as p-styrenesulfonic acid sodium salt (NaSS) and 2-acrylamide-2-methylpropane sulfonic acid sodium salt (NaAMPS).
摘要翻译：一种细胞培养支架，其含有具有由合成聚合物组成的网状结构的凝胶，使得培养细胞在较短时间内扩散，每单位面积吸附培养细胞数量大于使用具有网状结构的凝胶的情况的聚丙烯酸，同时利用低制造成本的合成聚合物，容易的质量控制和培养细胞中没有病毒感染的风险。用作细胞培养支架是含有通过聚合或共聚具有磺酸基的单体如对苯乙烯磺酸钠盐（NaSS）和2-丙烯酰胺-2-甲基丙磺酸钠盐（NaAMPS ）。

4. 发明申请

US20060003442A1 Cell culture scaffold, methods of manufacturing the scaffold and cell culture methods 失效
标题翻译：细胞培养支架，制造支架的方法和细胞培养方法
公开(公告)号：US20060003442A1
公开(公告)日：2006-01-05
申请号：US11050426
申请日：2005-02-04
申请人： Jian Gong , Yoshihito Osada , Yongmei Chen
发明人： Jian Gong , Yoshihito Osada , Yongmei Chen
IPC分类号： C12N5/06 , C12M3/00
CPC分类号： C12N5/0068 , C12M25/14 , C12N2533/30
摘要： A cell culture scaffold containing a gel having a network structure comprised of a synthetic polymer such that cultured cells spread in a shorter time and the number of adsorbed cultured cells per unit area is larger than in the case of using a gel having a network structure comprised of polyacrylic acid, while taking advantage of synthetic polymers with low manufacturing cost, easy quality control and no risk of virus infection in cultured cell. Used as the cell culture scaffold is a gel containing asynthetic polymer obtained by polymerization or copolymerization of a monomer having a sulfonic group such as p-styrenesulfonic acid sodium salt (NaSS) and 2-acrylamide-2-methylpropane sulfonic acid sodium salt (NaAMPS).
摘要翻译：一种细胞培养支架，其含有具有由合成聚合物组成的网状结构的凝胶，使得培养细胞在较短时间内扩散，每单位面积吸附培养细胞数量大于使用具有网状结构的凝胶的情况的聚丙烯酸，同时利用低制造成本的合成聚合物，容易的质量控制和培养细胞中没有病毒感染的风险。用作细胞培养支架是含有通过聚合或共聚具有磺酸基的单体如对苯乙烯磺酸钠盐（NaSS）和2-丙烯酰胺-2-甲基丙磺酸钠盐（NaAMPS）得到的合成聚合物的凝胶，。

5. 发明授权

US08148269B2 Boron nitride and boron-nitride derived materials deposition method 有权
标题翻译：氮化硼和氮化硼衍生材料的沉积方法
公开(公告)号：US08148269B2
公开(公告)日：2012-04-03
申请号：US12415759
申请日：2009-03-31
申请人： Mihaela Balseanu , Christopher D. Bencher , Yongmei Chen , Li Yan Miao , Victor Nguyen , Isabelita Roflox , Li-Qun Xia , Derek R. Witty
发明人： Mihaela Balseanu , Christopher D. Bencher , Yongmei Chen , Li Yan Miao , Victor Nguyen , Isabelita Roflox , Li-Qun Xia , Derek R. Witty
IPC分类号： H01L21/302 , H01L21/461
CPC分类号： H01L21/31144 , H01L21/3086 , H01L21/3105 , H01L21/31111 , H01L21/31122 , H01L21/318 , H01L21/76832 , H01L29/4966
摘要： A method and apparatus are provided to form spacer materials adjacent substrate structures. In one embodiment, a method is provided for processing a substrate including placing a substrate having a substrate structure adjacent a substrate surface in a deposition chamber, depositing a spacer layer on the substrate structure and substrate surface, and etching the spacer layer to expose the substrate structure and a portion of the substrate surface, wherein the spacer layer is disposed adjacent the substrate structure. The spacer layer may comprise a boron nitride material. The spacer layer may comprise a base spacer layer and a liner layer, and the spacer layer may be etched in a two-step etching process.
摘要翻译：提供了一种形成邻近衬底结构的间隔物材料的方法和装置。在一个实施例中，提供了一种用于处理衬底的方法，包括将具有邻近衬底表面的衬底结构的衬底放置在沉积室中，在衬底结构和衬底表面上沉积间隔层，以及蚀刻间隔层以暴露衬底结构和衬底表面的一部分，其中间隔层邻近衬底结构设置。间隔层可以包括氮化硼材料。间隔层可以包括基底间隔层和衬垫层，并且可以在两步蚀刻工艺中蚀刻间隔层。

6. 发明申请

US20090263972A1 BORON NITRIDE AND BORON-NITRIDE DERIVED MATERIALS DEPOSITION METHOD 有权
标题翻译：硼硝酸盐和硼 - 硼衍生物质沉积方法
公开(公告)号：US20090263972A1
公开(公告)日：2009-10-22
申请号：US12415759
申请日：2009-03-31
申请人： Mihaela Balseanu , Christopher D. Bencher , Yongmei Chen , Li Yan Miao , Victor Nguyen , Isabelita Roflox , Li-Qun Xia , Derek R. Witty
发明人： Mihaela Balseanu , Christopher D. Bencher , Yongmei Chen , Li Yan Miao , Victor Nguyen , Isabelita Roflox , Li-Qun Xia , Derek R. Witty
IPC分类号： H01L21/311
CPC分类号： H01L21/31144 , H01L21/3086 , H01L21/3105 , H01L21/31111 , H01L21/31122 , H01L21/318 , H01L21/76832 , H01L29/4966
摘要： A method and apparatus are provided to form spacer materials adjacent substrate structures. In one embodiment, a method is provided for processing a substrate including placing a substrate having a substrate structure adjacent a substrate surface in a deposition chamber, depositing a spacer layer on the substrate structure and substrate surface, and etching the spacer layer to expose the substrate structure and a portion of the substrate surface, wherein the spacer layer is disposed adjacent the substrate structure. The spacer layer may comprise a boron nitride material. The spacer layer may comprise a base spacer layer and a liner layer, and the spacer layer may be etched in a two-step etching process.
摘要翻译：提供了一种形成邻近衬底结构的间隔物材料的方法和装置。在一个实施例中，提供了一种用于处理衬底的方法，包括将具有邻近衬底表面的衬底结构的衬底放置在沉积室中，在衬底结构和衬底表面上沉积间隔层，以及蚀刻间隔层以暴露衬底结构和衬底表面的一部分，其中间隔层邻近衬底结构设置。间隔层可以包括氮化硼材料。间隔层可以包括基底间隔层和衬垫层，并且可以在两步蚀刻工艺中蚀刻间隔层。

7. 发明授权

US10035059B2 Flat ground cross-country type roller skate 有权
公开(公告)号：US10035059B2
公开(公告)日：2018-07-31
申请号：US15549672
申请日：2016-02-14
申请人： Yongmei Chen , Yongping Chen
发明人： Yongmei Chen , Yongping Chen
IPC分类号： A63C17/04 , A63C17/22 , A63C17/00
CPC分类号： A63C17/226 , A63C17/0046 , A63C17/008 , A63C17/02 , A63C17/04 , A63C17/062 , A63C2201/02 , A63C2203/20 , A63C2203/42
摘要： The present invention discloses a flat ground cross-country type roller skate comprising a skate body (1), wherein a wheel assembly at a lower part of the skate body, wherein the wheel assembly comprises a mounting seat (6) used to mount the skate body (1) and a hoisting mechanism disposed on the mounting seat (6). There are at least three wheel assemblies disposed on the hoisting mechanism, and each wheel assembly can hoist independently under the action of the hoisting mechanism. Thus, the wheel assemblies of the roller skate can be hoisted independently so as to adapt to various roads with uneven surface.

8. 发明申请

US20120148599A1 METHODS AND COMPOSITIONS FOR NEURAL DISEASE IMMUNOTHERAPY 有权
标题翻译：神经疾病免疫学方法与组合
公开(公告)号：US20120148599A1
公开(公告)日：2012-06-14
申请号：US13292633
申请日：2011-11-09
申请人： Jasvinder Atwal , Yongmei Chen , Cecilia Pui Chi Chiu , Robert A. Lazarus , Weiru Wang , Ryan J. Watts , Yan Wu , Yingnan Zhang
发明人： Jasvinder Atwal , Yongmei Chen , Cecilia Pui Chi Chiu , Robert A. Lazarus , Weiru Wang , Ryan J. Watts , Yan Wu , Yingnan Zhang
IPC分类号： A61K39/395 , C12N15/13 , C12N5/10 , C12P21/02 , G01N33/573 , C12N9/50 , C07K16/40 , C07K19/00
CPC分类号： C07K16/40 , A61K39/3955 , A61K47/6871 , A61K2039/505 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12P21/005 , G01N33/573
摘要： The invention provides antibodies to specific neural proteins and methods of using the same.
摘要翻译：本发明提供了针对特定神经蛋白的抗体及其使用方法。

9. 发明授权

US11148036B2 Multi-link wheel base and applications thereof 有权
公开(公告)号：US11148036B2
公开(公告)日：2021-10-19
申请号：US16608197
申请日：2019-06-25
申请人： Yongmei Chen , Yongping Chen
发明人： Yongmei Chen , Yongping Chen
IPC分类号： A63C17/01 , A63C17/00 , A63C17/02 , A63C17/14 , A63C17/22
摘要： A multi-link wheel base includes a main body composed of a plurality of links connected in series and wheels provided on the main body, and the wheels are provided on the link assembly the link assembly includes an intermediate link and an end link, wherein both sides of the intermediate link are provided with a rotational connection position, one side of the end link is provided with a rotational connection position, and the rotational connection positions on the adjacent link assemblies are rotationally connected by means of a connecting device.

10. 发明申请

US20150056800A1 Self-aligned interconnects formed using substractive techniques 有权
标题翻译：使用减法技术形成的自对准互连
公开(公告)号：US20150056800A1
公开(公告)日：2015-02-26
申请号：US13987667
申请日：2013-08-20
申请人： Bencherki Mebarki , Huixiong Dai , Yongmei Chen , He Ren , Mehul Naik
发明人： Bencherki Mebarki , Huixiong Dai , Yongmei Chen , He Ren , Mehul Naik
IPC分类号： H01L21/768
CPC分类号： H01L21/76897 , H01L21/32139 , H01L21/76885 , H01L23/53257 , H01L23/53276 , H01L2924/0002 , H01L2924/00
摘要： A method of forming an interconnect structure for semiconductor or MEMS structures at a 10 nm Node (16 nm HPCD) down to 5 nm Node (7 nm HPCD), or lower, where the conductive contacts of the interconnect structure are fabricated using solely subtractive techniques applied to conformal layers of conductive materials.
摘要翻译：在10nm节点（16nm HPCD）下至5nm节点（7nm HPCD）或更低的半导体或MEMS结构处形成互连结构的方法，其中互连结构的导电触点仅使用减法技术应用于导电材料的保形层。

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