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1. 发明授权

US6126836A Centrifugal flotation cell with rotating feed 失效
标题翻译：具有旋转进料的离心浮选槽
公开(公告)号：US6126836A
公开(公告)日：2000-10-03
申请号：US290371
申请日：1999-04-12
申请人： Jian Ding , Wan-Tai Yen , Alan R. Pindred
发明人： Jian Ding , Wan-Tai Yen , Alan R. Pindred
IPC分类号： B01D21/00 , B03D1/14 , B04B11/06 , B01D21/26
CPC分类号： B04B11/06 , B03D1/1418 , B03D1/1462 , B03D1/247 , B03D1/1412 , B03D2203/02
摘要： A superb centrifugal flotation cell with a rotating feed, is provided for use in an effective separation process to rapidly recover greater quantities of valuable fine particles. In the process, a slurry of fine particles is injected with air bubbles and moved downwardly through a stationary pipe and a rotating feed line comprising a centrifugal rotating downfeeder. The slurry is centrifugally discharged from the rotating downfeeder into the flotation chamber where the slurry is separated into a waste stream of non-floating gangue material and a particulate-enriched froth comprising air bubbles carrying a substantial amount of the valuable fine particles for further processing.
摘要翻译：提供具有旋转进料的超级离心浮选槽，用于有效的分离过程，以快速回收更多量的有价值的微粒。在此过程中，细小颗粒的浆料被注入气泡并向下移动通过固定管和包括离心旋转的下进料器的旋转进料管。将浆料从旋转的下进料器离心排放到浮选室中，其中浆料被分离成非浮动脉石材料的废物流和含有大量有用的细颗粒的气泡的颗粒富集泡沫用于进一步处理。

2. 发明授权

US5928125A Centrifugal flotation cell with rotating drum 失效
标题翻译：带旋转鼓的离心浮选槽
公开(公告)号：US5928125A
公开(公告)日：1999-07-27
申请号：US871516
申请日：1997-06-09
申请人： Jian Ding , Wan-Tai Yen , Alan R. Pindred
发明人： Jian Ding , Wan-Tai Yen , Alan R. Pindred
IPC分类号： B03D1/14 , B04B11/00 , B03D1/02 , B03D1/24
CPC分类号： B03D1/1418 , B03D1/1412 , B03D1/247
摘要： A user-friendly centrifugal flotation cell with a rotating drum, is provided for use in an efficient separation process to rapidly recover greater quantities of valuable fine particles. In the process, a slurry of fine particles is injected with air bubbles and moved downwardly through a stationary downfeeder to a centrifuge comprising a rotating flotation cell. The aerated slurry is centrifugally separated into a waste stream of non-floating gangue material and a particulate-enriched froth comprising air bubbles carrying a substantial amount of the valuable fine particles. The froth is processed by froth flotation in a froth flotation chamber.
摘要翻译：提供了一种用户友好的具有旋转鼓的离心浮选槽，用于有效的分离过程，以快速回收更多量的有价值的微粒。在此过程中，细小颗粒的浆料被注入气泡，并向下移动通过固定的向下进料器到包括旋转浮选槽的离心机。将充气浆料离心分离成非浮动脉石材料的废物流和含有大量有价值的细颗粒的气泡的颗粒富集泡沫。泡沫在泡沫浮选室中通过泡沫浮选进行处理。

3. 发明授权

US6059118A Process for recovering fine particulates in a centrifugal flotation cell with rotating drum 失效
标题翻译：在具有旋转滚筒的离心浮选槽中回收微细颗粒的方法
公开(公告)号：US6059118A
公开(公告)日：2000-05-09
申请号：US290367
申请日：1999-04-12
申请人： Jian Ding , Wan-Tai Yen , Alan R. Pindred
发明人： Jian Ding , Wan-Tai Yen , Alan R. Pindred
IPC分类号： B03D1/14 , B03D1/02
CPC分类号： B03D1/1418 , B03D1/1412 , B03D1/247
摘要： A user-friendly centrifugal flotation cell with a rotating drum, is provided for use in an efficient separation process to rapidly recover greater quantities of valuable fine particles. In the process, a slurry of fine particles is injected with air bubbles and moved downwardly through a stationary downfeeder to a centrifuge comprising a rotating flotation cell. The aerated slurry is centrifugally separated into a waste stream of non-floating gangue material and a particulate-enriched froth comprising air bubbles carrying a substantial amount of the valuable fine particles. The froth is processed by froth flotation in a froth flotation chamber.
摘要翻译：提供了一种用户友好的具有旋转鼓的离心浮选槽，用于有效的分离过程，以快速回收更多量的有价值的微粒。在此过程中，细小颗粒的浆料被注入气泡，并向下移动通过固定的向下进料器到包括旋转浮选槽的离心机。将充气浆料离心分离成非浮动脉石材料的废物流和含有大量有价值的细颗粒的气泡的颗粒富集泡沫。泡沫在泡沫浮选室中通过泡沫浮选进行处理。

4. 发明授权

US5914034A Centrifugal flotation cell with rotating feed 失效
公开(公告)号：US5914034A
公开(公告)日：1999-06-22
申请号：US871227
申请日：1997-06-09
申请人： Jian Ding , Wan-Tai Yen , Alan R. Pindred
发明人： Jian Ding , Wan-Tai Yen , Alan R. Pindred
IPC分类号： B01D21/00 , B03D1/14 , B04B11/06 , B01D21/26
CPC分类号： B04B11/06 , B03D1/1418 , B03D1/1462 , B03D1/247 , B03D1/1412 , B03D2203/02
摘要： A superb centrifugal flotation cell with a rotating feed, is provided for use in an effective separation process to rapidly recover greater quantities of valuable fine particles. In the process, a slurry of fine particles is injected with air bubbles and moved downwardly through a stationary pipe and a rotating feed line comprising a centrifugal rotating downfeeder. The slurry is centrifugally discharged from the rotating downfeeder into the flotation chamber where the slurry is separated into a waste stream of non-floating gangue material and a particulate-enriched froth comprising air bubbles carrying a substantial amount of the valuable fine particles for further processing.

5. 发明授权

US11648288B2 Composition comprising an algal proteoglycan extract and use thereof 有权
公开(公告)号：US11648288B2
公开(公告)日：2023-05-16
申请号：US16922585
申请日：2020-07-07
申请人： Qing Qi , Jian Ding
发明人： Qing Qi , Jian Ding
IPC分类号： A61K35/748 , A61K38/16 , A61K36/02 , A61P35/00 , A61K9/00 , A61K31/282 , A61K31/513 , A61K31/675 , A61K31/704 , A61K31/7048 , A61K45/06
CPC分类号： A61K38/164 , A61K9/0019 , A61K9/0053 , A61K31/282 , A61K31/513 , A61K31/675 , A61K31/704 , A61K31/7048 , A61K35/748 , A61K36/02 , A61K45/06 , A61P35/00
摘要： The present application provides use of an algal proteoglycan extract and a composition comprising the same in treating or preventing tumor, pain, inflammation or diseases mediated by inflammatory factors.

6. 发明申请

US20200376076A1 COMPOSITION COMPRISING AN ALGAL PROTEOGLYCAN EXTRACT AND USE THEREOF 审中-公开
公开(公告)号：US20200376076A1
公开(公告)日：2020-12-03
申请号：US16922585
申请日：2020-07-07
申请人： Qing Qi , Jian Ding
发明人： Qing Qi , Jian Ding
IPC分类号： A61K38/16 , A61K36/02 , A61P35/00 , A61K9/00 , A61K31/282 , A61K31/513 , A61K31/675 , A61K31/704 , A61K31/7048 , A61K35/748 , A61K45/06
摘要： The present application provides use of an algal proteoglycan extract and a composition comprising the same in treating or preventing tumor, pain, inflammation or diseases mediated by inflammatory factors.

7. 发明授权

US10597399B2 Substituted triazolopiperazine PARP inhibitor, preparation method therefor and use thereof 有权
公开(公告)号：US10597399B2
公开(公告)日：2020-03-24
申请号：US15987458
申请日：2018-05-23
申请人： Ao Zhang , Zehong Miao , Pingyuan Wang , Shanshan Song , Zilan Song , Xiajuan Huan , Zhoulong Fan , Jian Ding
发明人： Ao Zhang , Zehong Miao , Pingyuan Wang , Shanshan Song , Zilan Song , Xiajuan Huan , Zhoulong Fan , Jian Ding
IPC分类号： C07D487/04 , A61K31/444 , A61K31/437 , A61K31/502 , C07D471/04 , A61K31/4985 , A61P35/00
摘要： A class of substituted triazolopiperazine compounds represented by formula (I), tautomers, enantiomers, diastereomers, racemates, metabolites, metabolic precursors, and pharmaceutically acceptable salts, esters, prodrugs or hydrate thereof, a preparation methods therefor, intermediates and a use thereof in the preparation of drugs for prevention and treatment of diseases associated with PARP including various ischemic diseases, neurodegenerative diseases and cancers.

8. 发明授权

US09216962B2 Thiazole compounds, methods for preparation and use thereof 有权
标题翻译：噻唑化合物，其制备方法和用途
公开(公告)号：US09216962B2
公开(公告)日：2015-12-22
申请号：US14116944
申请日：2012-05-07
申请人： Fajun Nan , Fei Chen , Yangming Zhang , Jia Li , Yubo Zhou , Mingbo Su , Jian Ding , Linghua Meng , Xin Xie , Shixian Wang
发明人： Fajun Nan , Fei Chen , Yangming Zhang , Jia Li , Yubo Zhou , Mingbo Su , Jian Ding , Linghua Meng , Xin Xie , Shixian Wang
IPC分类号： C07D417/00 , C07D277/56 , C07D277/58 , C07D277/60 , C07D417/14 , C07D417/04
CPC分类号： C07D277/56 , C07D277/58 , C07D277/60 , C07D417/04 , C07D417/14
摘要： The present invention relates to thiazole compounds of formula I, the method for preparation and use thereof. More specifically, the present invention relates to novel derivatives of natural product largazole, the method for preparing them and their uses for treatments against tumor and multiple sclerosis as inhibitors of histone deacetylase.
摘要翻译：本发明涉及式I的噻唑化合物，其制备方法和用途。更具体地，本发明涉及天然产物大唑的新衍生物，其制备方法及其用于治疗肿瘤和多发性硬化的用途，作为组蛋白脱乙酰酶的抑制剂。

9. 发明授权

US09056874B2 Complement pathway modulators and uses thereof 有权
公开(公告)号：US09056874B2
公开(公告)日：2015-06-16
申请号：US13826725
申请日：2013-03-14
申请人： Christopher Michael Adams , Charles Babu , Michael Paul Capparelli , Jian Ding , Takeru Ehara , Keith Jendza , Nan Ji , Rajeshri Ganesh Karki , Toshio Kawanami , Liang Xue , Nello Mainolfi , James J. Powers , Michael H. Serrano-Wu , Chun Zhang
发明人： Christopher Michael Adams , Charles Babu , Michael Paul Capparelli , Jian Ding , Takeru Ehara , Keith Jendza , Nan Ji , Rajeshri Ganesh Karki , Toshio Kawanami , Liang Xue , Nello Mainolfi , James J. Powers , Michael H. Serrano-Wu , Chun Zhang
IPC分类号： C07D403/06 , C07D403/04 , C07D403/08 , C07D403/14 , C07D401/14 , C07D413/14 , C07D487/04 , C07D491/048 , A61K31/4184 , C07D413/06 , A61K31/423 , A61K31/4439 , A61K45/06
CPC分类号： A61K31/4184 , A61K31/423 , A61K31/4245 , A61K31/4439 , A61K45/06 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/08 , C07D403/14 , C07D413/06 , C07D413/14 , C07D487/04 , C07D491/048
摘要： The present invention provides a compound of formula I: a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

10. 发明申请

US20140128421A1 CAMPTOTHECIN COMPOUND CONTAINING STABLE 7-MEMBERED LACTONE RING, PREPARATION METHOD AND USE 有权
标题翻译：包含稳定的7会员手环的化合物，制备方法和用途
公开(公告)号：US20140128421A1
公开(公告)日：2014-05-08
申请号：US14112583
申请日：2012-04-13
申请人： Wei Lv , Shanbao Yu , Yu Luo , Yi Chen , Jian Ding
发明人： Wei Lv , Shanbao Yu , Yu Luo , Yi Chen , Jian Ding
IPC分类号： C07D491/22
CPC分类号： C07D491/22
摘要： Provided are a camptothecin compound containing 7-membered lactone ring, as shown in general formula I, and pharmaceutically acceptable salt thereof, as well as the preparation method and use thereof. In general formula I, R1 is H, a C1˜C3 alkyl, acetyl or propionyl; R2 is H, a C1˜C6 alkyl, a C3˜C6 cycloalkyl, piperidyl; or a C1˜C6 alkyl substituted by an amino; R3 is H, a C1˜C3 alkyl, or a C1˜C6 alkyl substituted by an amino; R4 is H, a hydroxyl, or a C1˜C6 alkoxy; R5 is H, or a C1˜C6 alkoxyl; or R4 and R5 are linked to each other to form —OCH2O— or —OCH2CH2O—. The compound has good anti-tumor activity, and can be clinically used via oral administration, intravenous injection, and intramuscular injection, among others.
摘要翻译：提供了如通式I所示的含有7-元内酯环的喜树碱化合物及其药学上可接受的盐以及其制备方法和用途。在通式Ⅰ中，R 1是H，C 1 -C 3烷基，乙酰基或丙酰基; R2是H，C1〜C6烷基，C3〜C6环烷基，哌啶基; 或被氨基取代的C 1-6烷基; R3是H，C1〜C3烷基或被氨基取代的C1〜C6烷基; R4是H，羟基或C1〜C6烷氧基; R5是H或C1〜C6烷氧基; 或R 4和R 5彼此连接形成-OCH 2 O-或-OCH 2 CH 2 O-。该化合物具有良好的抗肿瘤活性，可以通过口服给药，静脉内注射和肌内注射等临床使用。

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