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1. 发明申请

US20130135624A1 INFORMATION PROCESSING APPARATUS AND METHOD FOR FD-OCT 有权
标题翻译： FD-OCT的信息处理装置和方法
公开(公告)号：US20130135624A1
公开(公告)日：2013-05-30
申请号：US13480209
申请日：2012-05-24
申请人： Ji Hyun KIM , Jichai Jeong
发明人： Ji Hyun KIM , Jichai Jeong
IPC分类号： G01B9/02
CPC分类号： A61B1/00009 , G01B9/02044 , G01B9/0207 , G01B9/02087
摘要： An information processing apparatus for frequency domain optical coherence tomography comprises an image scanning unit that receives measurement data from an optical coherence tomography device, while moving a measurement point to the next adjacent point at each measurement time by controlling the optical coherence tomography device, and generates depth information based on the measurement data to produce a raw tomographic image. The apparatus includes a noise reduction unit that reduces noise from the raw tomographic image to produce a result tomographic image. The noise reduction unit reduces the noise from the raw tomographic image by subtracting the depth information generated by the image scanning unit at each measurement time from the depth information generated at another measurement time adjacent to said each measurement time.
摘要翻译：用于频域光学相干断层摄影的信息处理装置包括：图像扫描单元，其通过控制光学相干断层摄影装置在每个测量时间将测量点移动到下一相邻点，从光学相干断层摄影装置接收测量数据，并产生基于测量数据的深度信息以产生原始断层图像。该装置包括降噪单元，其降低来自原始断层图像的噪声，以产生结果断层图像。噪声降低单元通过从与每个测量时间相邻的另一测量时间产生的深度信息减去在每个测量时间由图像扫描单元生成的深度信息来减少来自原始断层图像的噪声。

2. 发明申请

US20090024882A1 METHOD FOR MONITORING AN INTERNAL CONTROL SIGNAL OF A MEMORY DEVICE AND APPARATUS THEREFOR 有权
标题翻译：用于监视存储器件的内部控制信号的方法及其装置
公开(公告)号：US20090024882A1
公开(公告)日：2009-01-22
申请号：US12243292
申请日：2008-10-01
申请人： Ji Hyun KIM , Young Jun NAM
发明人： Ji Hyun KIM , Young Jun NAM
IPC分类号： G11B20/20 , G06F11/00
CPC分类号： G11C29/1201 , G11C29/48
摘要： Disclosed is a method for monitoring an internal control signal of a memory device and an apparatus therefore. The method includes (a) generating a first signal having a first pulse width by a burst operation command, (b) receiving the first signal, and generating N−1 (where, N is a burst length) second signals having a second pulse width, (c) receiving the first signal and the second signals, and outputting a third signal by changing the first pulse width of the first signal and the second pulse width of the second signals in accordance with a variation of a frequency of a clock signal of the memory device, (d) outputting the third signal to an external pin of the memory device and monitoring the third signal, and (e) adjusting a pulse width of a signal that controls an operation of a data bus connecting a bit-line sense amplifier and a data sense amplifier using the third signal.
摘要翻译：公开了一种用于监视存储装置的内部控制信号的方法及装置。该方法包括：（a）通过脉冲串操作命令产生具有第一脉冲宽度的第一信号，（b）接收第一信号，并产生N-1（其中，N是脉冲串长度）具有第二脉冲宽度的第二信号，（c）接收第一信号和第二信号，并且通过根据第一信号的第一脉冲宽度和第二信号的第二脉冲宽度，根据时钟信号的频率的变化来输出第三信号存储器件，（d）将第三信号输出到存储器件的外部引脚并监视第三信号，以及（e）调节控制连接位线检测的数据总线的操作的信号的脉冲宽度放大器和使用第三信号的数据读出放大器。

3. 发明申请

US20120309675A1 PEPTIDE BFP4 FOR PROMOTING OSTEOGENESIS OR VASCULARIZATION AND USE THEREOF 审中-公开
标题翻译：用于促进卵泡发育或血管生成及其使用的肽BFP4
公开(公告)号：US20120309675A1
公开(公告)日：2012-12-06
申请号：US13486035
申请日：2012-06-01
申请人： Taek Rim YOON , Hyung Keun KIM , Ji Hyun KIM
发明人： Taek Rim YOON , Hyung Keun KIM , Ji Hyun KIM
IPC分类号： A61K38/10 , C12N15/12 , A61P9/10 , A61P19/10 , A61P19/02 , C07K7/08 , C12N15/82
CPC分类号： A61K38/10 , C07K14/51
摘要： Disclosed are a peptide for promoting osteogenesis and vascularization, and the use thereof. The peptide has a low molecular weight so that it can be economically produced. In addition, it promotes osteoblastic differentiation, thus inducing osteogenesis. Further, the peptide can promote the expression of VEGF, resulting in vascularization. Accordingly, the peptide is useful for the prophylaxis or therapy of ischemic diseases.
摘要翻译：公开了用于促进成骨和血管形成的肽及其用途。该肽具有低分子量，使得其可经济地生产。此外，它促进成骨细胞分化，从而诱导成骨。此外，肽可以促进VEGF的表达，导致血管形成。因此，该肽可用于预防或治疗缺血性疾病。

4. 发明申请

US20120213719A1 COSMETIC COMPOSITION FOR SKIN WHITENING 有权
标题翻译：化妆品组合物用于皮肤白化
公开(公告)号：US20120213719A1
公开(公告)日：2012-08-23
申请号：US13398353
申请日：2012-02-16
申请人： Hyun Seo KANG , Seung Hyun KANG , Ji Hyun KIM , Yong Joo Na , Jun Cheol CHO , Byung Guen CHAE
发明人： Hyun Seo KANG , Seung Hyun KANG , Ji Hyun KIM , Yong Joo Na , Jun Cheol CHO , Byung Guen CHAE
IPC分类号： A61K8/97 , A61Q19/02
CPC分类号： A61Q19/02 , A61K8/97 , A61K2800/5922
摘要： The present invention relates to a cosmetic composition for skin whitening containing at least two selected from the group consisting of a Magnolia obovata bark extract, a Citrus unshiu peel extract, a wild soybean extract, a Ginko biloba leaf extract, and a Honeysuckle extract, which composition depresses melanocytes, blocks stimulation from inflammation, UV radiation, or melasma blood vessels, strengthens melanocyte-supporting DEJs, inhibits skin hyper-pigmentation like skin spots and UV-induced skin tanning, and improves the skin tone and complexion look healthy and bright.
摘要翻译：本发明涉及一种皮肤美白用化妆品组合物，其含有选自玉兰薄荷皮树皮提取物，柑橘未提取物，野生大豆提取物，银杏叶提取物和金银花提取物中的至少两种，其中组合物抑制黑素细胞，阻止炎症，紫外线辐射或黑斑病血管的刺激，加强支持黑素细胞的DEJs，抑制皮肤色素沉着如皮肤斑点和紫外线诱导的皮肤晒黑，并改善肤色和肤色看起来健康和明亮。

5. 发明申请

US20110195906A1 OSTEOGENIC SYNTHETIC PEPTIDES, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND MEDIUM CONTAINING THE SAME 有权
标题翻译：毒素合成肽，包含其的药物组合物和含有它们的中间体
公开(公告)号：US20110195906A1
公开(公告)日：2011-08-11
申请号：US13093053
申请日：2011-04-25
申请人： Taek Rim YOON , Hyung Keun KIM , Ji Hyun KIM
发明人： Taek Rim YOON , Hyung Keun KIM , Ji Hyun KIM
IPC分类号： A61K38/10 , C07K7/08 , A61P19/08 , A61P19/10 , A61P19/02
CPC分类号： C07K14/51 , A61K38/00
摘要： Disclosed herein is an osteogenic synthetic peptide, derived from bone morphogenetic protein-7, consisting of a sequence of 15 amino acid residues. Provided are also a pharmaceutical composition and a medium composition comprising the same. Having remarkable activity related to promoting osteoblast differentiation, the osteogenic synthetic peptide is very useful in the treatment of osteoporosis, bone defects and/or osteoarthritis.
摘要翻译：本文公开了衍生自骨形态发生蛋白-7的成骨合成肽，其由15个氨基酸残基的序列组成。还提供了药物组合物和包含其的培养基组合物。与促进成骨细胞分化相关的显着活性，成骨合成肽在治疗骨质疏松症，骨缺损和/或骨关节炎方面非常有用。

6. 发明申请

US20110109362A1 CIRCUIT FOR CONTROLLING AN ENABLING TIME OF AN INTERNAL CONTROL SIGNAL ACCORDING TO AN OPERATING FREQUENCY OF A MEMORY DEVICE AND THE METHOD THEREOF 有权
标题翻译：用于控制根据存储器件的操作频率的内部控制信号的启动时间的电路及其方法
公开(公告)号：US20110109362A1
公开(公告)日：2011-05-12
申请号：US13008314
申请日：2011-01-18
申请人： Ji Hyun KIM , Young Jun NAM
发明人： Ji Hyun KIM , Young Jun NAM
IPC分类号： H03K3/017
CPC分类号： G11C29/028 , G11C7/1048 , G11C29/02 , G11C29/50012
摘要： Provided is a circuit for controlling a data bus connecting a bitline sense amplifier to a data sense amplifier in accordance with a variation of an operating frequency of a memory device, being comprised of a pulse width adjusting circuit for varying a pulse width of an input signal in accordance with the operating frequency of the memory device after receiving the input signal, a signal transmission circuit for buffing a signal outputted from the pulse width adjusting circuit, and an output circuit for outputting a first signal to control the data bus in response to a signal outputted from the signal transmission circuit.
摘要翻译：提供了一种用于根据存储器件的工作频率的变化来控制连接位线读出放大器与数据读出放大器的数据总线的电路，其包括用于改变输入信号的脉冲宽度的脉冲宽度调整电路在接收到输入信号之后，根据存储器件的工作频率，对从脉冲宽度调节电路输出的信号进行抛光的信号传输电路，以及输出电路，用于输出第一信号，以响应于信号从信号传输电路输出。

7. 发明申请

US20180008530A9 COSMETIC COMPOSITION FOR IMPROVING SKIN ELASTICITY 有权
公开(公告)号：US20180008530A9
公开(公告)日：2018-01-11
申请号：US14506128
申请日：2014-10-03
申请人： Eui Dong SON , Dae Jin MIN , Hui Kyoung CHANG , Hyun Jung CHOI , Seong A CHO , Ji Hyun KIM , Tae Ryong LEE
发明人： Eui Dong SON , Dae Jin MIN , Hui Kyoung CHANG , Hyun Jung CHOI , Seong A CHO , Ji Hyun KIM , Tae Ryong LEE
IPC分类号： A61K8/97 , A61K8/64 , A61K8/14 , A61K36/18 , A61Q19/08
CPC分类号： A61K8/97 , A61K8/14 , A61K8/64 , A61K36/18 , A61K2800/56 , A61Q19/08
摘要： Provided is a cosmetic composition for improving skin elasticity containing Phyllanthus urinaria extract and a polymersome in which an anti-aging peptide is stabilized as active ingredients. The cosmetic composition of the present disclosure is efficacious in improving skin wrinkles, restoring skin elasticity and increasing skin water content, and thus is effective for improving skin elasticity.

8. 发明申请

US20110275157A1 COMPOSITION FOR REPROGRAMMING SOMATIC CELLS TO GENERATE INDUCED PLURIPOTENT STEM CELLS, COMPRISING Bmi1 AND LOW MOLECULAR WEIGHT SUBSTANCE, AND METHOD FOR GENERATING INDUCED PLURIPOTENT STEM CELLS USING THE SAME 有权
标题翻译：用于复制SOMATIC细胞以产生诱导的包含Bmi1和低分子重量物质的诱导型干细胞的组合物，以及用于产生使用其的诱导的细胞干细胞的方法
公开(公告)号：US20110275157A1
公开(公告)日：2011-11-10
申请号：US13103611
申请日：2011-05-09
申请人： Seungkwon YOU , Jai-Hee MOON , Jun Sung KIM , Byung Sun YOON , Jung Han LEE , Eun Kyoung JUN , June Seok HEO , Ji Hyun KIM , Ji Hye HWANG , Su Hyun GWON
发明人： Seungkwon YOU , Jai-Hee MOON , Jun Sung KIM , Byung Sun YOON , Jung Han LEE , Eun Kyoung JUN , June Seok HEO , Ji Hyun KIM , Ji Hye HWANG , Su Hyun GWON
IPC分类号： C12N15/85 , C12N5/0735
CPC分类号： C12N15/873 , C12N5/0696 , C12N2501/065 , C12N2501/115 , C12N2501/70 , C12N2501/727 , C12N2501/998 , C12N2799/027
摘要： Provided is a composition for reprogramming somatic cells to generate embryonic stem cell-like cells, comprising: a) a Bmi1 (B cell-specific Moloney murine leukemia virus integration site 1) protein or a nucleic acid molecule encoding the Bmi1 protein; and b) at least one low molecular weight substance selected from the group consisting of a set of a MEK/ERK (mitogen-activated protein kinase/extracellular regulated kinase) inhibitor and a GSK (glycogen synthase kinase) inhibitor, a set of a G9a HMTase (G9a histone methyltransferase) inhibitor and a DMNT (DNA methyltransferase) inhibitor, and a histone deacetylase inhibitor. Also, a method is provided for reprogramming somatic cells to generate embryonic stem cell-like cells using the composition. In addition to reducing the number of the reprogramming factors conventionally needed, the composition and method allow the generation of pluripotent embryonic stem cell-like cells which have high potential in the cell therapy of various diseases.
摘要翻译：提供了一种用于重编程体细胞以产生胚胎干细胞样细胞的组合物，其包含：a）Bmi1（B细胞特异性莫洛尼鼠白血病病毒整合位点1）蛋白或编码Bmi1蛋白的核酸分子; 和b）至少一种选自MEK / ERK（丝裂原活化蛋白激酶/细胞外调节激酶）抑制剂和GSK（糖原合成酶激酶）抑制剂）的一组低分子量物质，一组G9a HMTase（G9a组蛋白甲基转移酶）抑制剂和DMNT（DNA甲基转移酶）抑制剂和组蛋白脱乙酰酶抑制剂。此外，提供了一种使用该组合物重新编程体细胞以产生胚胎干细胞样细胞的方法。除了减少常规需要的重新编程因子的数量之外，组合物和方法允许产生在各种疾病的细胞治疗中具有高潜力的多能胚胎干细胞样细胞。

9. 发明申请

US20150044265A1 COSMETIC COMPOSITION FOR IMPROVING SKIN ELASTICITY 有权
标题翻译：用于改善皮肤弹性的化妆品组合物
公开(公告)号：US20150044265A1
公开(公告)日：2015-02-12
申请号：US14506128
申请日：2014-10-03
申请人： Eui Dong SON , Dae Jin MIN , Hui Kyoung CHANG , Hyun Jung CHOI , Seong A CHO , Ji Hyun KIM , Tae Ryong LEE
发明人： Eui Dong SON , Dae Jin MIN , Hui Kyoung CHANG , Hyun Jung CHOI , Seong A CHO , Ji Hyun KIM , Tae Ryong LEE
IPC分类号： A61K8/97 , A61Q19/08 , A61K8/14 , A61K8/64
CPC分类号： A61K8/97 , A61K8/14 , A61K8/64 , A61K36/18 , A61K2800/56 , A61Q19/08
摘要： Provided is a cosmetic composition for improving skin elasticity containing Phyllanthus urinaria extract and a polymersome in which an anti-aging peptide is stabilized as active ingredients. The cosmetic composition of the present disclosure is efficacious in improving skin wrinkles, restoring skin elasticity and increasing skin water content, and thus is effective for improving skin elasticity.
摘要翻译：本发明提供一种用于改善皮肤弹性的化妆品组合物，其中含有叶黄芩提取物和抗衰老肽作为活性成分稳定的聚合物。本公开的化妆品组合物在改善皮肤皱纹，恢复皮肤弹性和增加皮肤含水量方面是有效的，因此对于改善皮肤弹性是有效的。

10. 发明申请

US20120196809A1 USE OF ICAM-1 FOR PREVENTION OR TREATMENT OF NEUROLOGICAL DISEASES 有权
标题翻译：使用ICAM-1预防或治疗神经病
公开(公告)号：US20120196809A1
公开(公告)日：2012-08-02
申请号：US13365022
申请日：2012-02-02
申请人： Yoon-Sun YANG , Won Il OH , Jong Wook CHANG , Ji Hyun KIM
发明人： Yoon-Sun YANG , Won Il OH , Jong Wook CHANG , Ji Hyun KIM
IPC分类号： A61K38/17 , A61P25/24 , A61P25/08 , A61P25/18 , A61P25/16 , A61P25/28 , A61P25/00
CPC分类号： A61K38/1774
摘要： The present invention relates to a pharmaceutical composition for the prevention or treatment of neurological disorders, comprising an ICAM-1 (intercellular adhesion molecule-1) protein, or a fragment or a variant thereof as an active ingredient, which can increase the expression of neprilysin to remove amyloid-beta (Aβ), a cause of dementia, and is thus useful in preventing or treating a neurological disease including Alzheimer's disease.
摘要翻译：本发明涉及一种用于预防或治疗神经系统疾病的药物组合物，其包含作为活性成分的ICAM-1（细胞间粘附分子-1）蛋白或其片段或变体，其可以增加内皮素的表达去除淀粉样蛋白β（A＆bgr），是痴呆的一个原因，因此可用于预防或治疗包括阿尔茨海默病在内的神经疾病。

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