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1. 发明授权

US5972926A Pyrazine fused to a cyclic peptide 失效
标题翻译：吡嗪与环肽融合
公开(公告)号：US5972926A
公开(公告)日：1999-10-26
申请号：US849456
申请日：1998-06-05
申请人： Jessie Sandosham , Johann Hiebl , Hermann Kollmann , Alan Cuthbertson , Peter Fischer , Michael Hartmann , Peter Kremminger , Franz Rovenszky , Mette Husbyn
发明人： Jessie Sandosham , Johann Hiebl , Hermann Kollmann , Alan Cuthbertson , Peter Fischer , Michael Hartmann , Peter Kremminger , Franz Rovenszky , Mette Husbyn
IPC分类号： C07D213/82 , C07D241/24 , C07D487/04 , A61K31/47 , C07D241/00
CPC分类号： C07D213/82 , C07D241/24 , C07D487/04
摘要： The present invention relates to pyrazine fused to a cyclic peptide which is capable of regulating, in particular stimulating, haematopoiesis.
摘要翻译： PCT No.PCT / GB95 / 02977 Sec。 371日期：1998年6月5日 102（e）1998年6月5日PCT 1995年12月20日PCT PCT。 WO96 / 19457 PCT出版物日期1996年6月27日本发明涉及与能够调节特别是刺激性造血作用的环肽融合的吡嗪。

2. 发明授权

US6124298A Pyrazinedicarboxylic-acid derivatives as cell proliferation regulators 失效
标题翻译：吡嗪二羧酸衍生物作为细胞增殖调节剂
公开(公告)号：US6124298A
公开(公告)日：2000-09-26
申请号：US377776
申请日：1999-08-20
申请人： Jessie Sandosham , Johann Hiebl , Hermann Kollmann , Alan Cuthbertson , Peter Fischer , Michael Hartmann , Peter Kremminger , Franz Rovenszky , Mette Husbyn
发明人： Jessie Sandosham , Johann Hiebl , Hermann Kollmann , Alan Cuthbertson , Peter Fischer , Michael Hartmann , Peter Kremminger , Franz Rovenszky , Mette Husbyn
IPC分类号： C07D213/82 , C07D241/24 , C07D487/04 , A61K31/4965 , C07D241/02 , C07D295/027
CPC分类号： C07D213/82 , C07D241/24 , C07D487/04
摘要： The present invention relates to novel pyrazine compounds and their use in the regulation of haematopoiesis, in particular in the stimulation of haematopoiesis, and in the treatment of bacterial, viral and fungal diseases.
摘要翻译：本发明涉及新颖的吡嗪化合物及其在调节造血作用，特别是刺激造血作用和用于治疗细菌，病毒和真菌疾病中的用途。

3. 发明授权

US5948759A Factor VII fragment 82-128 and its use in blood-clotting disorders 失效
标题翻译：因子VII片段82-128及其在血液凝固疾病中的应用
公开(公告)号：US5948759A
公开(公告)日：1999-09-07
申请号：US849248
申请日：1997-08-27
申请人： Mette Husbyn , Peter Fischer , Lars Orning
发明人： Mette Husbyn , Peter Fischer , Lars Orning
IPC分类号： C12N15/09 , A61K38/00 , A61K38/43 , A61P7/02 , A61P9/08 , A61P9/10 , C07K14/745 , C12N9/64 , A61K38/17 , A61K38/36 , C07K14/435
CPC分类号： C12N9/6437 , C12Y304/21021 , A61K38/00 , Y10S514/822
摘要： The present invention relates to peptide of the amino acid sequence of formula (I): 82 85 90 Glu Thr His Lys Asp Asp Gln Leu Ile 95 100 Cys Val Asn Glu Asn Gly Gly Cys Glu Gln 105 110 Tyr Cys Ser Asp His Thr Gly Thr Lys Arg 115 120 Ser Cys Arg Cys His Glu Gly Tyr Ser Leu 125 128 Leu Ala Asp Gly Val Ser Cys Thr (SEQ ID NO. 1) and functional equivalents thereof in which amino acids in the above stated sequence are modified or absent and wherein at least one of the cysteine residues may be blocked or replaced and wherein any cysteine residues which remain unblocked or unreplaced may be present in a disulphide bonded state. The invention also includes slats and derivatives of said peptides. The peptides and their salts and derivatives are useful in the treatment of blood clotting disorders.
摘要翻译： PCT No.PCT / GB95 / 02946 Sec。 371日期1997年8月27日第 102（e）日期1997年8月27日PCT提交1995年12月15日PCT公布。公开号WO96 / 18654 日期：1996年6月20日本发明涉及式（I）的氨基酸序列的肽： - 82 85 90 - Glu Thr His Lys Asp Asp Gln Leu Ile - - 95 100 - Cys Val Asn Glu Asn Gly Gly Cys Glu Gln - - 105 110 - Tyr Cys Ser Asp His Thr Gly Thr Lys Arg - - 115 120 - Ser Cys Arg Cys His Glu Gly Tyr Ser Leu - - 125 128 - Leu Ala Asp Gly Val Ser Cys Thr（SEQ ID NO.1 ）和其功能等同物，其中上述序列中的氨基酸被修饰或不存在，并且其中至少一个半胱氨酸残基可被阻断或替换，并且其中保持未阻断或未置换的任何半胱氨酸残基可以存在于二硫键中州。本发明还包括所述肽的板条和衍生物。肽及其盐和衍生物可用于治疗凝血障碍。

4. 发明授权

US10005225B2 Structure stamp, device and method of embossing 有权
公开(公告)号：US10005225B2
公开(公告)日：2018-06-26
申请号：US14425657
申请日：2012-09-06
申请人： Peter Fischer , Gerald Kreindl , Jakob Harming , Christine Thanner , Christian Schön
发明人： Peter Fischer , Gerald Kreindl , Jakob Harming , Christine Thanner , Christian Schön
IPC分类号： B29C59/02 , B29C59/00 , G03F7/00 , B82Y10/00 , B82Y40/00
CPC分类号： B29C59/022 , B29C59/002 , B29C2059/023 , B29K2821/003 , B82Y10/00 , B82Y40/00 , G03F7/0002 , G03F7/0017
摘要： A structure stamp with a flexible stamp which has a microstructured or nanostructured stamp surface for embossing of an embossing structure which corresponds to the stamp surface on an embossing surface, and a frame for clamping the stamp. Moreover, the invention relates to a device for embossing an embossing pattern on an embossing surface with the following features: a stamp receiver for accommodating and moving a structure stamp, an embossing material receiver for accommodating and placing an embossing material opposite the structure stamp, an embossing element drive for moving an embossing element along the structure stamp.

5. 发明授权

US09513881B2 System for the discovery and provisioning of artifacts and composites 有权
标题翻译：用于发现和配置工件和复合材料的系统
公开(公告)号：US09513881B2
公开(公告)日：2016-12-06
申请号：US12142952
申请日：2008-06-20
申请人： Peter Fischer , Hendrik Haddorp , Oliver Koeth , Andreas Nauerz
发明人： Peter Fischer , Hendrik Haddorp , Oliver Koeth , Andreas Nauerz
IPC分类号： G06F9/44 , G06F9/445
CPC分类号： G06F8/36 , G06F8/60
摘要： A system for assisted generation of composite applications which are composed of instantiable components includes a portal system executing in memory of a computer to:a) dynamically access a data source of one or more components being potentially suitable for being used within the composite application,b) parse the data source for a predetermined searched component according to a predetermined functionality specification standard,c) rank found components according to predetermined ranking criteria,d) define a list of selected usable components from the ranking,e) store at least a subset of the selected components locally, and,f) automatically deploy the composite application from the selected components.
摘要翻译： f）从所选组件自动部署组合应用程序。

6. 发明授权

US08332459B2 Federation of composite applications 失效
标题翻译：复合应用联合会
公开(公告)号：US08332459B2
公开(公告)日：2012-12-11
申请号：US12388648
申请日：2009-02-19
申请人： Michael Blum , Peter Fischer , Hendrik Haddorp , Stefan Hepper , Stefan Liesche , Michael Marks , Thomas Stober
发明人： Michael Blum , Peter Fischer , Hendrik Haddorp , Stefan Hepper , Stefan Liesche , Michael Marks , Thomas Stober
IPC分类号： G06F15/16
CPC分类号： G06F9/5038 , G06F9/44521 , G06F9/505 , Y02D10/22
摘要： A predetermined business task of a composite application can be fulfilled. The composite application can include a set of components. The composite application is instantiated by a template means and a predefined collaborative context module controls the interaction of the set of components during the runtime of the composite application. A set of components fulfilling individual services on individual different server systems is leveraged by the composite application. During the instantiation of the composite application from a template, the referenced components (as types) are instantiated leading to runtime instances of these components. The interaction of the different components is controlled on individual different server systems utilizing a primary context module. The primary context module communicates with an appropriate collaborative module implemented locally on the respective set of servers, where the local context modules act as secondary context modules in relation to the primary context modules. For each of the secondary context modules, local components communicate to control the interaction of components.
摘要翻译：组合应用程序的预定业务任务可以满足。复合应用程序可以包括一组组件。复合应用程序由模板手段实例化，预定义的协作上下文模块控制组合应用程序运行时期间组件集的交互。复合应用程序利用一组满足个别不同服务器系统上个性化服务的组件。在从模板实例化复合应用程序期间，引用的组件（作为类型）被实例化，导致这些组件的运行时实例。利用主上下文模块，在不同的服务器系统上控制不同组件的交互。主上下文模块与在相应的服务器集合上本地实现的适当的协作模块进行通信，其中本地上下文模块作为相对于主上下文模块的辅助上下文模块。对于每个辅助上下文模块，本地组件进行通信以控制组件的交互。

7. 发明申请

US20120236311A1 METHOD FOR MONITORING AND/OR REGULATING FUEL CELLS 有权
标题翻译：用于监测和/或调节燃料电池的方法
公开(公告)号：US20120236311A1
公开(公告)日：2012-09-20
申请号：US13512602
申请日：2010-12-06
申请人： Hans Bettermann , Peter Fischer , Arno Goedecke Reichelt , Irmgard Buder , Volker Peinecke
发明人： Hans Bettermann , Peter Fischer , Arno Goedecke Reichelt , Irmgard Buder , Volker Peinecke
IPC分类号： G01N21/59
CPC分类号： H01M8/04447 , G01N21/67 , H01M8/04089 , H01M8/04455 , Y02E60/50
摘要： The invention relates to a method for monitoring and/or regulating fuel cells, in particular comprising determining the composition of the operating gases of the fuel cells. The method comprises the following steps: introducing the gas mixture to be analyzed into a measuring cell (1); producing an arc in the measuring cell (1); absorbing the radiation emitted by the arc; optical filtering of the emitted radiation and/or spectral decomposition of the emitted radiation; converting the emitted radiation into an electric signal; evaluating the electric signal.
摘要翻译：本发明涉及用于监测和/或调节燃料电池的方法，特别地包括确定燃料电池的工作气体的组成。该方法包括以下步骤：将要分析的气体混合物引入测量池（1）中; 在测量单元（1）中产生电弧; 吸收由电弧发射的辐射; 所发射的辐射的光学滤波和/或发射的辐射的光谱分解; 将发射的辐射转换成电信号; 评估电信号。

8. 发明授权

US08235639B2 Method for producing adhesive-bound book blocks from gathered signatures 有权
标题翻译：从收集的签名生产粘合剂书本块的方法
公开(公告)号：US08235639B2
公开(公告)日：2012-08-07
申请号：US12196685
申请日：2008-08-22
申请人： Theo Hug , Peter Fischer , Heinz Bötchi
发明人： Theo Hug , Peter Fischer , Heinz Bötchi
IPC分类号： B42C11/00 , B42C13/00 , B42C11/02 , B42C11/04 , B42B9/00
CPC分类号： B42C19/08 , B42C9/0006 , B42C11/02 , B65H2301/321 , B65H2301/363 , B65H2405/50 , B65H2701/182 , B65H2701/18282
摘要： A method for producing adhesive-bound book blocks from gathered signatures for which the individual signatures forming a non-bound book block are supplied while positioned on the spine on a transfer section to an opened conveying clamp on a perfect binder and are subsequently held while clamped in by the closed conveying clamp along the flat outer surfaces. The gathered signatures of a book block are released in an additional conveying section from the conveying clamp in order to be aligned while guided. Prior to leaving the conveying section for aligning the signatures, the signatures are clamped in once more by the conveying clamps along the flat outer surfaces, so that they can be conveyed to further processing locations.
摘要翻译：一种用于从收集的签名生成粘合剂书本块的方法，其中形成无约束书本块的各个签名在位于转印部分上的书脊上的同时被提供给在完美的粘合剂上的打开的输送夹具上，并且随后被夹持通过沿着平坦的外表面的封闭输送夹具。书本块的收集的签名从输送夹具释放在另外的输送部分中，以便在被引导的同时被对准。在离开用于对准签名的输送部分之前，通过输送夹具沿着平坦的外表面再次夹紧签名，使得它们可以被输送到另外的处理位置。

9. 发明申请

US20090250616A1 INTEGRATED MULTI-CHANNEL TIME-TO-DIGITAL CONVERTER FOR TIME-OF-FLIGHT PET 有权
标题翻译：用于飞行时间飞行器的集成多通道时数转换器
公开(公告)号：US20090250616A1
公开(公告)日：2009-10-08
申请号：US12304135
申请日：2007-05-29
申请人： Torsten J. Solf , Peter Fischer
发明人： Torsten J. Solf , Peter Fischer
IPC分类号： G01T1/166 , G01R35/00 , H03H11/26 , G01J5/10
CPC分类号： G01T1/2985 , A61B6/037 , G04F10/005
摘要： In a radiation detector (10) for a time of flight positron emission tomography (PET) scanner (2), a radiation sensitive member (20) generates a signal (22) indicative of a radiation detection event. A time to digital converter (34) includes digital delay elements (40) operatively interconnected as a ring oscillator (36, 36′) and readout circuitry (50, 52, 60, 82, 84, 86, 88) configured to generate a timestamp for the radiation detection event based at least on a state of the ring oscillator when the signal is generated. Delay trim elements (46) operatively connected to the digital delay elements set a substantially common delay for the digital delay elements. Additionally or alternatively, the digital delay elements (40) include readout buffers (48′) having transition times substantially longer than a delay of the digital delay elements, analog to digital converters (82, 84) digitize values of the delay elements, and decoding circuitry (86, 88) computes the state of the ring oscillator (36′) based on the digitized values.
摘要翻译：在用于飞行时间正电子发射断层摄影（PET）扫描仪（2）的放射线检测器（10）中，辐射敏感部件（20）产生指示辐射检测事件的信号（22）。时间到数字转换器（34）包括作为环形振荡器（36,36'）可操作地互连的数字延迟元件（40）和被配置为生成时间戳的读出电路（50,52,60,82,84,86,88）用于当产生信号时至少基于环形振荡器的状态的辐射检测事件。可操作地连接到数字延迟元件的延迟微调元件（46）为数字延迟元件设置基本上公用的延迟。附加地或替代地，数字延迟元件（40）包括读出缓冲器（48'），其具有比数字延迟元件的延迟更多的转换时间，模数转换器（82,84）数字化延迟元件的值，并且解码电路（86,88）基于数字化值来计算环形振荡器（36'）的状态。

10. 发明申请

US20080003080A1 Glue applicator for applying an adhesive to the spine or adjacent areas of a book block being conducted past the glue applicator in a transport direction 有权
标题翻译：用于将粘合剂施加到书芯的脊柱或相邻区域的胶水涂抹器在输送方向上穿过胶涂机
公开(公告)号：US20080003080A1
公开(公告)日：2008-01-03
申请号：US11823718
申请日：2007-06-28
申请人： Christian Abegglen , Peter Fischer
发明人： Christian Abegglen , Peter Fischer
IPC分类号： B42C9/00
CPC分类号： B42C9/0031 , Y10S412/90 , Y10S412/901
摘要： A glue applicator for applying an adhesive to the spine of a book block or to adjacent areas of a book block of stacked printed sheets being conducted past the glue applicator includes a tank holding liquid adhesive, into which at least one glue applicator roll dips to take up the adhesive and to transfer it to the spine of the book block, the roll being driven in the same travel direction as the book block, wherein the glue applicator roll works together with a doctor blade which is installed above the surface of the glue in the tank, and wherein the doctor blade determines the thickness of the adhesive film to be transferred to the spine of the book block through variation of its distance from the glue applicator roll, and where an actuating element for the doctor blade is positively connected to a cam disk, which is driven by a motor.
摘要翻译：用于将粘合剂施加到书芯的脊柱或通过涂胶器穿过的堆叠的打印片材的书本块的相邻区域的胶粘剂施加器包括容纳液体粘合剂的容器，至少一个胶水涂布器辊浸入其中粘合剂并将其转移到书芯的脊柱上，该卷筒以与书芯相同的行进方向驱动，其中胶涂机辊与安装在胶水表面上方的刮刀一起工作罐，并且其中刮刀通过改变其距离胶粘剂辊的距离来确定待传送到书芯的脊柱的粘合剂膜的厚度，并且其中用于刮刀的致动元件被正确连接到凸轮盘由电机驱动。

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