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1. 发明申请

US20050043361A1 MitoNEET polypeptide from mitochondrial membranes, modulators thereof, and methods of using the same 审中-公开
标题翻译：来自线粒体膜的MitoNEET多肽，其调节剂及其使用方法
公开(公告)号：US20050043361A1
公开(公告)日：2005-02-24
申请号：US10728679
申请日：2003-12-05
申请人： Jerry Colca , William McDonald
发明人： Jerry Colca , William McDonald
IPC分类号： C07K14/47 , C07K14/705 , A61K31/4439
CPC分类号： C07K14/47 , C07K14/705
摘要： The invention relates generally to a family of polypeptides from mitochondrial membranes, which bind insulin sensitizing, antidiabetic thiazolodinediones, and nucleic acid sequences encoding the family of polypeptides. The invention relates to methods of identifying therapeutic agents that bind to the polypeptides of the present invention. The invention further relates to methods useful for treating or modulating metabolic disorders in mammals in need of such biological effect.
摘要翻译：本发明一般涉及来自线粒体膜的多肽结合胰岛素敏化，抗糖尿病性噻唑烷二酮类和编码多肽家族的核酸序列。本发明涉及鉴定结合本发明多肽的治疗剂的方法。本发明还涉及可用于治疗或调节需要这种生物效应的哺乳动物代谢紊乱的方法。

2. 发明授权

US08371188B2 Transmission control assembly having a locking mechanism 有权
标题翻译：传动控制组件具有锁定机构
公开(公告)号：US08371188B2
公开(公告)日：2013-02-12
申请号：US12244029
申请日：2008-10-02
申请人： Christopher Bortolon , William McDonald
发明人： Christopher Bortolon , William McDonald
IPC分类号： B60K20/00 , G05G5/00 , F16H59/04
CPC分类号： F16H59/0204 , F16H59/10 , F16H61/22 , F16H61/24 , F16H2059/0239 , Y10T74/20085 , Y10T74/20159
摘要： A transmission control assembly having a housing and a bracket pivotally coupled to the housing for movement along a first path. A yoke is selectively coupled to the bracket for concurrent movement with the bracket along the first path. The yoke is also selectively pivotal about a second pivot axis substantially transverse to the first pivot axis for movement along a second path. A tactile device is supported by the bracket and engageable with the housing. The tactile device moves about the bracket during the movement of the bracket along the first path. A locking mechanism is coupled between the bracket and the yoke. The locking mechanism moves between an unlocked position when the yoke is coupled to the bracket for allowing movement of the tactile device and a locked position engaged with the tactile device when the yoke moves along the second path for preventing movement of the tactile device.
摘要翻译：传动控制组件，其具有壳体和支架，所述壳体和支架枢转地联接到所述壳体以沿着第一路径移动。轭被选择性地联接到支架，用于与支架沿着第一路径同时移动。轭还可以围绕基本上横向于第一枢转轴线的第二枢转轴线选择性地枢转，以便沿第二路径移动。触觉装置由支架支撑并与壳体接合。在支架沿着第一路径运动期间，触觉装置围绕支架移动。锁定机构联接在支架和轭架之间。当磁轭联接到支架上时，锁定机构在解锁位置之间移动，以允许触觉装置的移动，并且当磁轭沿着第二路径移动以防止触觉装置的移动时，与触觉装置接合的锁定位置。

3. 发明申请

US20070188847A1 MEMS device and method 审中-公开
标题翻译： MEMS器件及方法
公开(公告)号：US20070188847A1
公开(公告)日：2007-08-16
申请号：US11353473
申请日：2006-02-14
申请人： William McDonald , Armando Gonzalez
发明人： William McDonald , Armando Gonzalez
IPC分类号： G02B26/00
CPC分类号： G02B26/0833 , G02B26/0841
摘要： A micro-mirror hinge assembly for use in a MEMS device such as a DMD, and method. In a preferred embodiment, a first hinge member is mounted to a substrate by one or more via structures that may be integrally-formed with the hinge-member to facilitate torsional deformation. A second hinge member also configured for torsional deformation is mounted to and usually above the first hinge member so that deformation of the second hinge member occasions deformation of the first. Additional hinge members, each mounted to at least one other hinge member, may also be present. A mirror or similar reflecting surface is mounted to the second hinge member at one or more mirror vias. The MEMS device may include means for selectively inducing mirror reorientation, which in turn causes deformation in the hinge members of the hinge assembly.
摘要翻译：用于诸如DMD的MEMS装置中的微镜铰链组件和方法。在优选实施例中，第一铰链构件通过一个或多个通孔结构安装到基底上，该通孔结构可以与铰链构件整体形成以便于扭转变形。还构造成用于扭转变形的第二铰链构件安装到第一铰链构件上并且通常位于第一铰链构件上方，使得第二铰链构件的变形会使第一铰链构件发生变形。每个安装到至少一个其它铰链构件的铰链构件也可以存在。镜子或类似的反射表面在一个或多个镜子通孔处安装到第二铰链构件。 MEMS器件可以包括用于选择性地引起镜子重新定向的装置，这又引起铰链组件的铰链构件的变形。

4. 发明申请

US20070125578A1 Wellbore motor having magnetic gear drive 有权
标题翻译：井筒电机有磁齿轮传动
公开(公告)号：US20070125578A1
公开(公告)日：2007-06-07
申请号：US11604660
申请日：2006-11-27
申请人： William McDonald , Timothy Price , Gareth Hatch
发明人： William McDonald , Timothy Price , Gareth Hatch
IPC分类号： E21B4/00
CPC分类号： E21B4/006 , F16H49/005 , H02K49/102
摘要： A wellbore motor includes a means for converting flow of fluid in the wellbore into rotational energy. A magnetic gear member is operatively coupled at an input thereof to the means for converting. A wellbore rotary tool is coupled to an output of the magnetic gear member.
摘要翻译：井眼马达包括用于将井眼中的流体的流量转换成旋转能量的装置。磁齿轮构件在其输入处可操作地耦合到用于转换的装置。井筒旋转工具联接到磁齿轮构件的输出。

5. 发明申请

US20060053110A1 Out-of-home advertising inventory ratings methods and systems 审中-公开
标题翻译：户外广告库存评级方法和系统
公开(公告)号：US20060053110A1
公开(公告)日：2006-03-09
申请号：US11219453
申请日：2005-09-02
申请人： William McDonald , Thomas Adler , Stephen Lawe , Wendy Welles , Michael McCoy
发明人： William McDonald , Thomas Adler , Stephen Lawe , Wendy Welles , Michael McCoy
IPC分类号： G06F17/30
CPC分类号： G06Q30/02
摘要： Methods, systems and programs for estimating exposure to outdoor advertising are provided. In certain embodiments, exposure data is produced based on respondent data and traffic data. In certain embodiments, exposure data is produced based on outdoor inventory data and traffic data.
摘要翻译：提供了估算暴露于户外广告的方法，系统和程序。在某些实施例中，基于受访者数据和交通数据产生曝光数据。在某些实施例中，曝光数据是基于户外库存数据和交通数据产生的。

6. 发明申请

US20050282991A1 High impact poly (urethane urea) polysulfides 审中-公开
标题翻译：高抗冲聚氨酯脲多硫化物
公开(公告)号：US20050282991A1
公开(公告)日：2005-12-22
申请号：US11141636
申请日：2005-05-31
申请人： Nina Bojkova , Robert Smith , Robert Herold , Chandra Rao , William McDonald , Vidhu Nagpal , Marvin Graham , Phillip Yu , Suresh Sawant , Michael Okoroafor
发明人： Nina Bojkova , Robert Smith , Robert Herold , Chandra Rao , William McDonald , Vidhu Nagpal , Marvin Graham , Phillip Yu , Suresh Sawant , Michael Okoroafor
IPC分类号： C08G18/00 , C08G18/12 , C08G18/38 , C08G18/42 , C08G18/50 , C08G18/66 , C08G18/72 , C08G18/75 , C08G18/77
CPC分类号： C08G18/3876 , C08G18/12 , C08G18/4277 , C08G18/5072 , C08G18/52 , C08G18/6607 , C08G18/6611 , C08G18/664 , C08G18/6644 , C08G18/722 , C08G18/724 , C08G18/758 , C08G18/775 , G02B1/04 , C08G18/3237 , C08G18/3225 , C08L75/04 , C08L81/00
摘要： The present invention relates to a sulfur-containing polyureaurethane and a method of preparing said polyureaurethane. In an embodiment, the sulfur-containing polyureaurethane adapted to have a refractive index of at least 1.57, an Abbe number of at least 32 and a density of less than 1.3 grams/cm3, when at least partially cured.
摘要翻译：本发明涉及一种含硫聚脲氨基甲酸酯及其制备方法。在一个实施方案中，适于具有至少1.57的折射率，至少32的阿贝数和小于1.3克/厘米3的密度的含硫聚脲聚氨酯，当至少部分地治愈

7. 发明授权

US08066029B2 Persuasive environmental recovery system 有权
标题翻译：说服性环境恢复系统
公开(公告)号：US08066029B2
公开(公告)日：2011-11-29
申请号：US12143399
申请日：2008-06-20
申请人： William McDonald , Walter L. Dabbs , Paul Willman
发明人： William McDonald , Walter L. Dabbs , Paul Willman
IPC分类号： F16K21/18
CPC分类号： E03F7/00 , E03B7/071 , Y02A20/15 , Y10T137/0324 , Y10T137/6991 , Y10T137/7287 , Y10T137/742 , Y10T137/8342 , Y10T137/86381
摘要： A sewer backup alarm and overflow prevention device eliminates raw sewage spills by preventing pressure buildup in sewer drains. One or more sewage level sensors may be coupled to an alarm and/or to an automatic water main shut-off valve. The level sensor may detect excess fluid levels in a sewer lateral line. The sewer backup alarm and overflow prevention device may include a joggle which is a component of a non-mechanical backflow prevention device. The level sensor may detect fluid levels in the lower portion of the joggle and activate the automatic water main shut-off valve and/or the alarm. The sewer backup alarm and overflow prevention device may include at least one two-way, in-line cleanout tube which may extend vertically upwardly from the joggle. The level sensor may be mounted in the vertical cleanout tube. The components may be contained within a seamless polyethylene vault for ease of installation and protection against root intrusion.
摘要翻译：下水道备用报警和溢流防止装置通过防止下水道排水管中的压力累积，消除原污水泄漏。一个或多个污水液位传感器可以联接到报警器和/或自动水主截止阀。水位传感器可以检测下水道侧线中的过多液体水平。下水道备用报警和溢流防止装置可以包括作为非机械回流防止装置的部件的jog子。液位传感器可以检测槌下部的液位，并激活自动水主截止阀和/或报警器。下水道备用报警和溢流防止装置可以包括至少一个双向的在线清洁管，其可以从耙子垂直向上延伸。液位传感器可以安装在垂直清洗管中。组件可以包含在无缝聚乙烯保险库内，以便于安装和防止根部侵入。

8. 发明申请

US20110125593A1 ONLINE MARKETING PAYMENT MONITORING METHOD AND SYSTEM 审中-公开
标题翻译：在线营销支付监测方法与系统
公开(公告)号：US20110125593A1
公开(公告)日：2011-05-26
申请号：US12675747
申请日：2008-09-02
申请人： Robert Wright , David M. Schrader , Dale Couch , Robert Charest , Anibal Santiago , William McDonald , Edward H. Benson, III , Josh Griffin , Robert Sefick , Mark Ebel
发明人： Robert Wright , David M. Schrader , Dale Couch , Robert Charest , Anibal Santiago , William McDonald , Edward H. Benson, III , Josh Griffin , Robert Sefick , Mark Ebel
IPC分类号： G06Q30/00 , G06F15/16
CPC分类号： G06Q30/02 , G06Q30/0277 , G06Q30/0641
摘要： A method of collecting and correlating information about user interactions with a plurality of websites including adding a first cookie from a first website, the first cookie recording information concerning interactions of a user with the first website; adding a second cookie from a second website, the second cookie recording information concerning interactions of the user with the second website; initiating a tracking pixel on a third website; capturing information from the first and second cookie; and determining a first contribution of the first website and a second contribution of the second website to interests in the third website.
摘要翻译：一种收集和关联与多个网站的用户交互的信息的方法，包括从第一网站添加第一cookie，关于用户与第一网站的交互的第一cookie记录信息; 从第二网站添加第二个cookie，第二个cookie记录关于用户与第二个网站的交互的信息; 在第三个网站上发起跟踪像素; 捕获来自第一和第二cookie的信息; 以及确定第一网站的第一贡献和第二网站的第二贡献对第三网站的兴趣。

9. 发明申请

US20070155940A1 IMPACT RESISTANT POLYUREAURETHANE LENS 审中-公开
标题翻译：耐冲击聚氨酯透镜
公开(公告)号：US20070155940A1
公开(公告)日：2007-07-05
申请号：US11685794
申请日：2007-03-14
申请人： Vidhu Nagpal , William McDonald , Robert Smith
发明人： Vidhu Nagpal , William McDonald , Robert Smith
IPC分类号： C08G18/00
CPC分类号： C08G18/758 , C08G18/12 , C08G18/3206 , C08G18/4018 , C08G18/4277 , C08G18/6611 , C08G18/6644 , C08G18/6677 , G02B1/041 , C08L75/04 , C08G18/3814 , C08G18/3243 , C08G18/3225
摘要： The present invention relates to a polyether-containing polyureaurethane lens. The polyureaurethane lens can include a prepolymer comprising a polyisocyanate and a polyether-containing polyol material that can be reacted with an amine-containing curing agent to produce the polyureaurethane lens of the present invention. The polyether-containing polyureaurethane lens can have a hard coating on both surfaces and a maximum center thickness of 2.2 mm in a piano configuration, with an impact resistance of at least 148 feet per second as defined by The High Impact Test.
摘要翻译：本发明涉及含聚醚的聚脲氨酯透镜。聚脲氨酯透镜可以包括含有多异氰酸酯和含聚醚的多元醇材料的预聚物，其可与含胺固化剂反应以制备本发明的聚脲聚氨酯透镜。含聚醚的聚脲氨基甲酸酯透镜可以在两个表面上具有硬涂层，并且在钢琴结构中可以具有2.2mm的最大中心厚度，其耐冲击性为“高冲击试验”所定义的至少148英尺/秒。

10. 发明申请

US20100083784A1 TRANSMISSION CONTROL ASSEMBLY HAVING A LOCKING MECHANISM 有权
标题翻译：具有锁定机构的变速箱控制装置
公开(公告)号：US20100083784A1
公开(公告)日：2010-04-08
申请号：US12244029
申请日：2008-10-02
申请人： Christopher Bortolon , William McDonald
发明人： Christopher Bortolon , William McDonald
IPC分类号： G05G5/02
CPC分类号： F16H59/0204 , F16H59/10 , F16H61/22 , F16H61/24 , F16H2059/0239 , Y10T74/20085 , Y10T74/20159
摘要： A transmission control assembly having a housing and a bracket pivotally coupled to the housing for movement along a first path. A yoke is selectively coupled to the bracket for concurrent movement with the bracket along the first path. The yoke is also selectively pivotal about a second pivot axis substantially transverse to the first pivot axis for movement along a second path. A tactile device is supported by the bracket and engageable with the housing. The tactile device moves about the bracket during the movement of the bracket along the first path. A locking mechanism is coupled between the bracket and the yoke. The locking mechanism moves between an unlocked position when the yoke is coupled to the bracket for allowing movement of the tactile device and a locked position engaged with the tactile device when the yoke moves along the second path for preventing movement of the tactile device.
摘要翻译：传动控制组件，其具有壳体和支架，所述壳体和支架枢转地联接到所述壳体以沿着第一路径移动。轭被选择性地联接到支架，用于与支架沿着第一路径同时移动。轭还可以围绕基本上横向于第一枢转轴线的第二枢转轴线选择性地枢转，以便沿第二路径移动。触觉装置由支架支撑并与壳体接合。在支架沿着第一路径运动期间，触觉装置围绕支架移动。锁定机构联接在支架和轭架之间。当磁轭联接到支架上时，锁定机构在解锁位置之间移动，以允许触觉装置的移动，并且当磁轭沿着第二路径移动以防止触觉装置的移动时，与触觉装置接合的锁定位置。

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