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1. 发明申请

US20070134255A1 Hmpv treatment with ribavirin and anti-hmpv antibody 审中-公开
标题翻译：使用利巴韦林和抗hmpv抗体进行Hmpv治疗
公开(公告)号：US20070134255A1
公开(公告)日：2007-06-14
申请号：US10555329
申请日：2004-05-03
申请人： Jeroen Maertzdorf , James Simon
发明人： Jeroen Maertzdorf , James Simon
IPC分类号： A61K39/42 , A61K31/7056
CPC分类号： A61K31/7056 , A61K38/21 , A61K2300/00
摘要： The invention relates to antimicrobial agents and antibodies and compositions comprising such agents and antibodies to treat and/or prevent respiratory and related diseases, in particular those caused by human metapneumovirus. Provided is a method for treating or preventing respiratory tract infections in a subject infected with a mammalian MPV, said method comprising administering a nucleoside analog, preferably Ribavirin or a derivative thereof, and an antimicrobial neutralising antibody, preferably an anti-hMPV antibody to said subject, and use of said nucleoside analog and antimicrobial neutralising antibody for the manufacture of a medicament for treating or preventing respiratory tract infections in a subject infected with a mammalian MPV.
摘要翻译：本发明涉及抗微生物剂和抗体以及包含此类试剂和抗体的组合物，其用于治疗和/或预防呼吸系统和相关疾病，特别是由人类偏肺病毒引起的疾病。提供一种治疗或预防感染哺乳动物MPV的受试者的呼吸道感染的方法，所述方法包括向所述受试者施用核苷类似物，优选利巴韦林或其衍生物，抗微生物中和抗体，优选抗HMPV抗体以及所述核苷类似物和抗微生物中和抗体用于制备用于治疗或预防感染哺乳动物MPV的受试者的呼吸道感染的药物的用途。

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