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1. 发明授权

US07653226B2 Flexible generation of digitally reconstructed radiographs 有权
标题翻译：灵活地生成数字重建的X光片
公开(公告)号：US07653226B2
公开(公告)日：2010-01-26
申请号：US10953342
申请日：2004-09-29
申请人： Jens Gühring , Sebastian Vogt , Ali Khamene
发明人： Jens Gühring , Sebastian Vogt , Ali Khamene
IPC分类号： G06K9/00 , G06K9/40 , A61B5/00 , A61B6/00
CPC分类号： G06T15/08
摘要： A system and corresponding method for flexible generation of digitally reconstructed radiograph (DRR) images on a graphics processing unit (GPU) are provided, the system including a processor, an imaging adapter in signal communication with the processor for receiving volumetric data, an integration unit in signal communication with the processor for integrating the volumetric data into incremental line integrals, and a modeling unit in signal communication with the processor for modeling composite line integrals from the incremental line integrals; and the corresponding method including receiving three-dimensional (3D) volumetric data into a graphics pipeline, integrating the 3D volumetric data into incremental line integrals along a plurality of viewing rays, modeling composite line integrals from the incremental line integrals, and adding the incremental line integrals for each composite line integral to form pixels of the DRR image.
摘要翻译：提供了一种用于在图形处理单元（GPU）上灵活生成数字重建X射线照片（DRR）图像的系统和相应方法，该系统包括处理器，与处理器进行信号通信的成像适配器，用于接收体积数据，整合单元与处理器的信号通信，用于将体积数据集成到增量线积分中，以及与处理器进行信号通信的建模单元，用于从增量线积分建模复合线积分; 以及相应的方法，包括将三维（3D）体积数据接收到图形管线中，将3D体积数据集成到沿着多个观察射线的增量线积分中，从增量线积分建模复合线积分，以及将增量线每个复合线的积分积分以形成DRR图像的像素。

2. 发明授权

US09681925B2 Method for augmented reality instrument placement using an image based navigation system 有权
公开(公告)号：US09681925B2
公开(公告)日：2017-06-20
申请号：US11107640
申请日：2005-04-15
申请人： Fred S. Azar , Ali Khamene , Frank Sauer , Sebastian Vogt
发明人： Fred S. Azar , Ali Khamene , Frank Sauer , Sebastian Vogt
IPC分类号： A61B5/05 , A61B90/00 , A61B34/20 , A61B90/11 , A61B34/10
CPC分类号： A61B90/36 , A61B34/10 , A61B34/20 , A61B90/11 , A61B90/361 , A61B2034/107 , A61B2090/365
摘要： A system and method for instrument placement using an image based navigation system is disclosed. A target of interest is identified in a medical image of a patient. An image plane is displayed that goes through a center of the target. The image plane has a configurable orientation. The image plane is used to select a path for an instrument from a position on the patient's skin to the center of the target. A trajectory plane is viewed from a tip of the instrument to the center of the target. The trajectory plane reflects an orientation of the instrument. A particular trajectory plane is selected that is representative of a desired orientation of the instrument. An image of the particular trajectory plane is frozen. The instrument can then be inserted using a virtual guide and is navigated toward the target.

3. 发明申请

US20050203380A1 System and method for augmented reality navigation in a medical intervention procedure 有权
标题翻译：医疗干预程序中增强现实导航的系统和方法
公开(公告)号：US20050203380A1
公开(公告)日：2005-09-15
申请号：US11056317
申请日：2005-02-11
申请人： Frank Sauer , Ali Khamene , Sebastian Vogt
发明人： Frank Sauer , Ali Khamene , Sebastian Vogt
IPC分类号： A61B5/05
CPC分类号： G02B7/002 , A61B34/10 , A61B34/20 , A61B90/20 , A61B90/36 , A61B90/361 , A61B2034/107 , A61B2034/2055 , A61B2034/2072 , A61B2090/371 , G02B27/017 , G02B2027/0138 , G02B2027/0187 , G06F3/012
摘要： A method for augmented reality navigation of a medical intervention includes providing a stereoscopic head mounted display, the display including a pair of stereo viewing cameras, at least one tracking camera, and a stereoscopic guidance display. During a medical intervention on a patient, the patient's body pose is determined from a rigid body transformation between the tracking camera and frame markers on the scanning table, and the pose of an intervention instrument with respect to the table is determined. A visual representation of the patient overlaid with an image of the intervention target, the instrument, and a path for guiding the instrument to perform said medical intervention is displayed in the stereoscopic guidance display.
摘要翻译：用于医疗干预的增强现实导航的方法包括提供立体头戴式显示器，所述显示器包括一对立体观看照相机，至少一个跟踪相机和立体指导显示器。在患者的医疗干预中，患者的身体姿势由跟踪摄像机和扫描台上的帧标记之间的刚性身体变换确定，并且确定干预仪器相对于桌子的姿势。在立体指导显示中显示覆盖有介入目标图像，仪器和用于引导仪器执行所述医疗干预的路径的患者的视觉表示。

4. 发明申请

US20050271302A1 GPU-based image manipulation method for registration applications 有权
标题翻译：基于GPU的图像处理方法用于注册应用
公开(公告)号：US20050271302A1
公开(公告)日：2005-12-08
申请号：US11109126
申请日：2005-04-19
申请人： Ali Khamene , Christophe Chefd'hotel , Jens Guhring , Bernhard Geiger , Sebastian Vogt
发明人： Ali Khamene , Christophe Chefd'hotel , Jens Guhring , Bernhard Geiger , Sebastian Vogt
IPC分类号： G06K9/00 , G06K9/64 , G06T7/00
CPC分类号： G06T15/005 , G06K9/00986 , G06K9/64 , G06T1/20 , G06T7/35 , G06T2200/28 , G06T2207/10072 , G06T2207/10116 , G06T2207/10132 , G06T2207/30004
摘要： Exemplary systems and methods for performing registration applications are provided. An exemplary system includes a central processing unit (CPU) for transferring a plurality of images to a graphics processing unit (GPU); wherein the GPU performs a registration application on the plurality of images to produce a registration result, and wherein the GPU returns the registration result to the CPU. An exemplary method includes the steps of transferring a plurality of images from a central processing unit (CPU) to a graphics processing unit (GPU); performing a registration application on the plurality of images using the GPU; transferring the result of the step of performing from the GPU to CPU.
摘要翻译：提供了用于执行注册申请的示例性系统和方法。示例性系统包括用于将多个图像传送到图形处理单元（GPU）的中央处理单元（CPU）; 其中所述GPU对所述多个图像执行注册应用以产生注册结果，并且其中所述GPU将所述注册结果返回给所述CPU。一种示例性方法包括将多个图像从中央处理单元（CPU）传送到图形处理单元（GPU）的步骤; 使用所述GPU对所述多个图像执行注册应用; 将执行步骤的结果从GPU传送到CPU。

5. 发明申请

US20050238223A1 Flexible generation of digitally reconstructed radiographs 有权
标题翻译：灵活地生成数字重建的X光片
公开(公告)号：US20050238223A1
公开(公告)日：2005-10-27
申请号：US10953342
申请日：2004-09-29
申请人： Jens Guhring , Sebastian Vogt , Ali Khamene
发明人： Jens Guhring , Sebastian Vogt , Ali Khamene
IPC分类号： G06K9/00 , G06K9/36 , G06T15/08
CPC分类号： G06T15/08
摘要： A system and corresponding method for flexible generation of digitally reconstructed radiograph (DRR) images on a graphics processing unit (GPU) are provided, the system including a processor, an imaging adapter in signal communication with the processor for receiving volumetric data, an integration unit in signal communication with the processor for integrating the volumetric data into incremental line integrals, and a modeling unit in signal communication with the processor for modeling composite line integrals from the incremental line integrals; and the corresponding method including receiving three-dimensional (3D) volumetric data into a graphics pipeline, integrating the 3D volumetric data into incremental line integrals along a plurality of viewing rays, modeling composite line integrals from the incremental line integrals, and adding the incremental line integrals for each composite line integral to form pixels of the DRR image.
摘要翻译：提供了一种用于在图形处理单元（GPU）上灵活生成数字重建X射线照片（DRR）图像的系统和相应方法，该系统包括处理器，与处理器进行信号通信的成像适配器，用于接收体积数据，整合单元与处理器的信号通信，用于将体积数据集成到增量线积分中，以及与处理器进行信号通信的建模单元，用于从增量线积分建模复合线积分; 以及相应的方法，包括将三维（3D）体积数据接收到图形管线中，将3D体积数据集成到沿着多个观察射线的增量线积分中，从增量线积分建模复合线积分，以及将增量线每个复合线的积分积分以形成DRR图像的像素。

6. 发明申请

US20050251030A1 Method for augmented reality instrument placement using an image based navigation system 有权
标题翻译：使用基于图像的导航系统增强现实仪器放置的方法
公开(公告)号：US20050251030A1
公开(公告)日：2005-11-10
申请号：US11107640
申请日：2005-04-15
申请人： Fred Azar , Ali Khamene , Frank Sauer , Sebastian Vogt
发明人： Fred Azar , Ali Khamene , Frank Sauer , Sebastian Vogt
IPC分类号： A61B5/05 , A61B6/00 , A61B19/00
CPC分类号： A61B90/36 , A61B34/10 , A61B34/20 , A61B90/11 , A61B90/361 , A61B2034/107 , A61B2090/365
摘要： A system and method for instrument placement using an image based navigation system is disclosed. A target of interest is identified in a medical image of a patient. An image plane is displayed that goes through a center of the target. The image plane has a configurable orientation. The image plane is used to select a path for an instrument from a position on the patient's skin to the center of the target. A trajectory plane is viewed from a tip of the instrument to the center of the target. The trajectory plane reflects an orientation of the instrument. A particular trajectory plane is selected that is representative of a desired orientation of the instrument. An image of the particular trajectory plane is frozen. The instrument can then be inserted using a virtual guide and is navigated toward the target.
摘要翻译：公开了一种使用基于图像的导航系统进行仪器放置的系统和方法。在患者的医学图像中识别感兴趣的目标。显示穿过目标中心的图像平面。图像平面具有可配置的方向。图像平面用于从患者皮肤上的位置到目标的中心选择仪器的路径。从仪器的尖端到目标的中心观察轨迹平面。轨迹平面反映了仪器的方向。选择代表仪器的期望取向的特定轨迹平面。特定轨迹平面的图像被冻结。然后可以使用虚拟指南插入仪器并导航到目标。

7. 发明授权

US07774044B2 System and method for augmented reality navigation in a medical intervention procedure 有权
标题翻译：医疗干预程序中增强现实导航的系统和方法
公开(公告)号：US07774044B2
公开(公告)日：2010-08-10
申请号：US11056317
申请日：2005-02-11
申请人： Frank Sauer , Ali Khamene , Sebastian Vogt
发明人： Frank Sauer , Ali Khamene , Sebastian Vogt
IPC分类号： A61B5/05 , G09G5/00
CPC分类号： G02B7/002 , A61B34/10 , A61B34/20 , A61B90/20 , A61B90/36 , A61B90/361 , A61B2034/107 , A61B2034/2055 , A61B2034/2072 , A61B2090/371 , G02B27/017 , G02B2027/0138 , G02B2027/0187 , G06F3/012
摘要： A method for augmented reality navigation of a medical intervention includes providing a stereoscopic head mounted display, the display including a pair of stereo viewing cameras, at least one tracking camera, and a stereoscopic guidance display. During a medical intervention on a patient, the patient's body pose is determined from a rigid body transformation between the tracking camera and frame markers on the scanning table, and the pose of an intervention instrument with respect to the table is determined. A visual representation of the patient overlaid with an image of the intervention target, the instrument, and a path for guiding the instrument to perform said medical intervention is displayed in the stereoscopic guidance display.
摘要翻译：用于医疗干预的增强现实导航的方法包括提供立体头戴式显示器，所述显示器包括一对立体观看照相机，至少一个跟踪相机和立体指导显示器。在患者的医疗干预中，患者的身体姿势由跟踪摄像机和扫描台上的帧标记之间的刚性身体变换确定，并且确定干预仪器相对于桌子的姿势。在立体指导显示中显示覆盖有介入目标图像，仪器和用于引导仪器执行所述医疗干预的路径的患者的视觉表示。

8. 发明申请

US20060281971A1 METHOD AND APPARATUS FOR MINIMALLY INVASIVE SURGERY USING ENDOSCOPES 有权
标题翻译：使用内镜治疗微创外科手术的方法和装置
公开(公告)号：US20060281971A1
公开(公告)日：2006-12-14
申请号：US11383598
申请日：2006-05-16
申请人： Frank Sauer , Ali Khamene , Sebastian Vogt
发明人： Frank Sauer , Ali Khamene , Sebastian Vogt
IPC分类号： A61B1/04
CPC分类号： A61B34/20 , A61B1/0005 , A61B1/04 , A61B90/36 , A61B2090/364 , A61B2090/376 , G16H50/50
摘要： A method and apparatus for presenting three-dimensional data to a physician is provided to facilitate the flexible navigation of an endoscope and surgical instruments with respect to anatomical structures. In accordance with a first embodiment a first set of data corresponding to a three dimensional model of a patient's anatomy is received. This three-dimensional model may be rendered from images taken in CT or MRI scanning, as discussed above In accordance with this embodiment, this model is then combined with a second set of data corresponding to a view obtained from an endoscope. In another embodiment, the view from the illustrative endoscope is displayed as an inset image on the display of the three-dimensional image. In yet another embodiment, the three-dimensional image comprises a graphical representation of at least a first surgical instrument, such as said endoscope. The surgeon may select among various combinations of views and may zoom in or out from any particular view.
摘要翻译：提供了一种用于向医师呈现三维数据的方法和装置，以便于内窥镜和外科器械相对于解剖结构的灵活导航。根据第一实施例，接收对应于患者解剖结构的三维模型的第一组数据。这种三维模型可以从CT或MRI扫描中拍摄的图像呈现，如上所述根据本实施例，该模型然后与对应于从内窥镜获得的视图的第二组数据组合。在另一个实施例中，来自说明性内窥镜的视图作为插入图像被显示在三维图像的显示器上。在另一个实施例中，三维图像包括至少第一外科器械（例如所述内窥镜）的图形表示。外科医生可以在各种视图组合中进行选择，并且可以放大或缩小任何特定视图。

9. 发明授权

US09289267B2 Method and apparatus for minimally invasive surgery using endoscopes 有权
标题翻译：使用内窥镜进行微创手术的方法和装置
公开(公告)号：US09289267B2
公开(公告)日：2016-03-22
申请号：US11383598
申请日：2006-05-16
申请人： Frank Sauer , Ali Khamene , Sebastian Vogt
发明人： Frank Sauer , Ali Khamene , Sebastian Vogt
IPC分类号： A61B1/00 , A61B1/04 , A62B1/04 , A61B19/00 , G06F19/00
CPC分类号： A61B34/20 , A61B1/0005 , A61B1/04 , A61B90/36 , A61B2090/364 , A61B2090/376 , G16H50/50
摘要： A method and apparatus for presenting three-dimensional data to a physician is provided to facilitate the flexible navigation of an endoscope and surgical instruments with respect to anatomical structures. In accordance with a first embodiment a first set of data corresponding to a three dimensional model of a patient's anatomy is received. This three-dimensional model may be rendered from images taken in CT or MRI scanning, as discussed above. In accordance with this embodiment, this model is then combined with a second set of data corresponding to a view obtained from an endoscope. In another embodiment, the view from the illustrative endoscope is displayed as an inset image on the display of the three-dimensional image. In yet another embodiment, the three-dimensional image comprises a graphical representation of at least a first surgical instrument, such as said endoscope. The surgeon may select among various combinations of views and may zoom in or out from any particular view.
摘要翻译：提供了一种用于向医师呈现三维数据的方法和装置，以便于内窥镜和外科器械相对于解剖结构的灵活导航。根据第一实施例，接收对应于患者解剖结构的三维模型的第一组数据。如上所述，该三维模型可以从在CT或MRI扫描中拍摄的图像呈现。根据本实施例，然后将该模型与对应于从内窥镜获得的视图的第二组数据组合。在另一个实施例中，来自说明性内窥镜的视图作为插入图像被显示在三维图像的显示器上。在另一个实施例中，三维图像包括至少第一外科器械（例如所述内窥镜）的图形表示。外科医生可以在各种视图组合中进行选择，并且可以放大或缩小任何特定视图。

10. 发明授权

US07920144B2 Method and system for visualization of dynamic three-dimensional virtual objects 有权
标题翻译：动态三维虚拟物体可视化的方法与系统
公开(公告)号：US07920144B2
公开(公告)日：2011-04-05
申请号：US11328562
申请日：2006-01-10
申请人： Sebastian Vogt , Frank Sauer , Ali Khamene
发明人： Sebastian Vogt , Frank Sauer , Ali Khamene
IPC分类号： G06T15/70
CPC分类号： G06T13/20 , G06T15/005
摘要： A method for visualization of dynamic three-dimensional (3D) virtual objects comprises storing a plurality of static 3D key-models respectively describing a dynamic 3D object in at least one of a number of poses and shapes; and rendering the dynamic 3D object by interpolation of the 3D key-models by performing the interpolation in a vertex shader program of a programmable graphics processing unit (GPU).
摘要翻译：一种用于可视化动态三维（3D）虚拟对象的方法包括以多个姿态和形状中的至少一个存储分别描述动态3D对象的多个静态3D关键字模型; 以及通过在可编程图形处理单元（GPU）的顶点着色器程序中执行插值来对3D键模型进行插值来呈现动态3D对象。

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