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1. 发明申请

US20070049901A1 Method of treating acne with stratum corneum piercing device 审中-公开
标题翻译：用角质层穿刺装置治疗痤疮的方法
公开(公告)号：US20070049901A1
公开(公告)日：2007-03-01
申请号：US11409454
申请日：2006-04-21
申请人： Jeffrey Wu , Jue Liu , Ying Sun , Justin McDonough , Danilo Lambino , Mariam Maghribi
发明人： Jeffrey Wu , Jue Liu , Ying Sun , Justin McDonough , Danilo Lambino , Mariam Maghribi
IPC分类号： A61M31/00
CPC分类号： A61M37/0015 , A61B2017/00765 , A61M37/00 , A61M2037/0023 , A61M2037/0046 , A61N1/306 , A61N1/325
摘要： The invention features a method of treating acne by piercing the stratum corneum of skin in need of such treatment with a stratum corneum-piercing device that contains at east one stratum corneum-piercing microprotrusion and a compressible cover such that the compressible cover substantially encases the at least one stratum corneum-piercing microprotrusion, and wherein upon contacting the skin with the compressible cover, the at least one stratum corneum-piercing microprotrusion protrudes from the compressible cover and pierces the stratum corneum of the skin.
摘要翻译：本发明的特征在于一种通过用东方一角质层穿刺微灌注的角质层刺穿装置刺穿需要这种治疗的皮肤角质层来治疗痤疮的方法，使得可压缩盖基本上包围在至少一个角质层刺穿微灌注，并且其中当使皮肤与可压缩覆盖层接触时，至少一个角质层刺穿的微量突出从可压缩盖突出并刺穿皮肤的角质层。

2. 发明申请

US20070270738A1 Method of treating ACNE with stratum corneum piercing patch 审中-公开
标题翻译：用角质层刺穿补片处理ACNE的方法
公开(公告)号：US20070270738A1
公开(公告)日：2007-11-22
申请号：US11690960
申请日：2007-03-26
申请人： Jeffrey Wu , Jue Liu , Ying Sun , Justin McDonough , Danilo Lambino , Mariam Maghribi
发明人： Jeffrey Wu , Jue Liu , Ying Sun , Justin McDonough , Danilo Lambino , Mariam Maghribi
IPC分类号： A61B17/20 , A61B17/00
CPC分类号： A61B17/205 , A61B2017/00747
摘要： The invention features a method of treating acne by piercing the stratum corneum of skin in need of such treatment with a stratum corneum-piercing device that contains at least one stratum corneum-piercing microprotrusion and a compressible cover such that the compressible cover substantially encases the at least one stratum corneum-piercing microprotrusion, and wherein upon contacting the skin with the compressible cover, the at least one stratum corneum-piercing microprotrusion protrudes from the compressible cover and pierces the stratum corneum of the skin.
摘要翻译：本发明的特征在于一种通过用包含至少一种角质层穿孔微灌注的角质层刺穿装置刺穿需要这种治疗的皮肤角质层来治疗痤疮的方法，使得可压缩盖基本上包围在至少一个角质层刺穿微灌注，并且其中当使皮肤与可压缩覆盖层接触时，至少一个角质层刺穿的微量突出从可压缩盖突出并刺穿皮肤的角质层。

3. 发明申请

US20060253079A1 Stratum corneum piercing device 审中-公开
标题翻译：角质层刺穿装置
公开(公告)号：US20060253079A1
公开(公告)日：2006-11-09
申请号：US11113952
申请日：2005-04-25
申请人： Justin McDonough , Jue-Chen Liu , Ying Sun , Danilo Lambino , Jeffrey Wu , Mariam Maghribi
发明人： Justin McDonough , Jue-Chen Liu , Ying Sun , Danilo Lambino , Jeffrey Wu , Mariam Maghribi
IPC分类号： A61M5/00
CPC分类号： A61M37/0015 , A61B2017/00765 , A61M37/00 , A61M2037/0023 , A61M2037/0046 , A61N1/306 , A61N1/325
摘要： The present invention features a stratum corneum-piercing device including a microprotrusion member having a skin-contacting surface and plurality of stratum corneum piercing microprotrusions thereon, the device being adapted to move the microprotrusion member lateral to the surface of the skin surface upon contact with the skin.
摘要翻译：本发明的特征在于一种角质层穿刺装置，其包括具有皮肤接触表面和多个角质层穿孔微突起的微突出物构件，该装置适于在接触到皮肤表面时将微突出物横向移动到皮肤表面的表面皮肤。

4. 发明申请

US20080009802A1 Method of treating acne with stratum corneum piercing device 审中-公开
标题翻译：用角质层穿刺装置治疗痤疮的方法
公开(公告)号：US20080009802A1
公开(公告)日：2008-01-10
申请号：US11113937
申请日：2005-04-25
申请人： Danilo Lambino , Jue-Chen Liu , Ying Sun , Justin McDonough , Jeffrey Wu , Mariam Maghribi
发明人： Danilo Lambino , Jue-Chen Liu , Ying Sun , Justin McDonough , Jeffrey Wu , Mariam Maghribi
IPC分类号： A61M5/00
CPC分类号： A61N1/30 , A61B17/205 , A61B2017/00747 , A61B2017/00765 , A61M37/0015 , A61M2037/0023 , A61M2037/0046 , A61N1/205 , A61N1/328
摘要： The invention features a method of treating acne by piercing the stratum corneum of skin in need of such treatment with a stratum corneum-piercing device including a microprotrusion member having a skin-contacting surface and plurality of stratum corneum-piercing microprotrusions thereon.
摘要翻译：本发明的特征在于一种通过用角质层刺穿装置刺穿需要这种治疗的皮肤角质层来治疗痤疮的方法，所述角质层穿刺装置包括具有皮肤接触表面的微量输注构件和在其上的多个角质层穿孔微突起。

5. 发明申请

US20060253078A1 Method of treating skin disorders with stratum corneum piercing device 审中-公开
标题翻译：用角质层穿刺装置治疗皮肤病的方法
公开(公告)号：US20060253078A1
公开(公告)日：2006-11-09
申请号：US11113890
申请日：2005-04-25
申请人： Jeffrey Wu , Jue-Chen Liu , Ying Sun , Justin McDonough , Danilo Lambino , Mariam Maghribi
发明人： Jeffrey Wu , Jue-Chen Liu , Ying Sun , Justin McDonough , Danilo Lambino , Mariam Maghribi
IPC分类号： A61M5/00
CPC分类号： A61M37/0015 , A61B2017/00765 , A61M37/00 , A61M2037/0023 , A61M2037/0046 , A61N1/306 , A61N1/325
摘要： The present invention features a device having a barrier membrane contacting surface, the device containing: a power source; a first conductive electrode; a second conductive electrode; and a reservoir; wherein said power source is in electric communication with said first conductive electrode and said second conductive electrode, wherein said first conductive electrode and said second conductive electrode are arranged such that they are both capable of being in ionic communication with a carrier upon the inclusion of said carrier to said reservoir; and the use thereof.
摘要翻译：本发明的特征在于具有阻挡膜接触表面的装置，该装置包括：电源; 第一导电电极; 第二导电电极; 和一个水库; 其中所述电源与所述第一导电电极和所述第二导电电极电连通，其中所述第一导电电极和所述第二导电电极被布置成使得它们能够在包含所述第一导电电极和所述第二导电电极时能够与载体离子连通载体到所述储存器; 及其用途。

6. 发明申请

US20060113537A1 Electronic unit integrated into a flexible polymer body 有权
公开(公告)号：US20060113537A1
公开(公告)日：2006-06-01
申请号：US11326967
申请日：2006-01-05
申请人： Peter Krulevitch , Mariam Maghribi , William Benett , Julie Hamilton , Klint Rose , James Davidson , Mark Strauch
发明人： Peter Krulevitch , Mariam Maghribi , William Benett , Julie Hamilton , Klint Rose , James Davidson , Mark Strauch
IPC分类号： H01L31/0376
CPC分类号： H01L25/165 , B81C1/0023 , H01L21/6835 , H01L31/048 , H01L31/0543 , H01L2221/68345 , H01L2924/0002 , H01L2924/09701 , H01L2924/19041 , H01L2924/19105 , Y02E10/52 , H01L2924/00
摘要： A peel and stick electronic system comprises a silicone body, and at least one electronic unit operatively connected to the silicone body. The electronic system is produce by providing a silicone layer on a substrate, providing a metal layer on the silicone layer, and providing at least one electronic unit connected to the metal layer.

7. 发明申请

US20080103462A1 WOUND HEALING PATCH WITH INTEGRAL PASSIVE VACUUM AND ELECTROSTIMULATION 审中-公开
标题翻译：具有整体被动真空和电沉积的创伤治疗贴
公开(公告)号：US20080103462A1
公开(公告)日：2008-05-01
申请号：US11876175
申请日：2007-10-22
申请人： Stuart Wenzel , Mariam Maghribi , Mark Huang , Zara Sieh , Michael V. Williamson
发明人： Stuart Wenzel , Mariam Maghribi , Mark Huang , Zara Sieh , Michael V. Williamson
IPC分类号： A61M35/00
CPC分类号： A61M27/00 , A61F13/023 , A61F2013/00174 , A61F2013/00187 , A61F2013/0028 , A61F2013/0054 , A61F2013/00902 , A61F2013/00919 , A61F2013/00931 , A61M1/0003 , A61M1/0011 , A61M1/0088 , A61N1/205
摘要： In one example, the present invention is directed to wound-healing patche that passively or actively draw fluids from a wound using an internal, integral vacuum source. The patches may also include electrodes and electronics for electrostimulation, and bioactive compounds that promote healing, such as anti-inflammatory agents.
摘要翻译：在一个实例中，本发明涉及伤口愈合贴片，其被动地或主动地使用内部的整体式真空源从伤口吸取流体。贴剂还可以包括用于电刺激的电极和电子元件，以及促进愈合的生物活性化合物，例如抗炎剂。

8. 发明申请

US20060052656A1 Implantable devices using magnetic guidance 审中-公开
标题翻译：使用磁性引导的植入式装置
公开(公告)号：US20060052656A1
公开(公告)日：2006-03-09
申请号：US10938816
申请日：2004-09-09
申请人： Mariam Maghribi , Peter Krulevitch , James Davidson , Julie Hamilton
发明人： Mariam Maghribi , Peter Krulevitch , James Davidson , Julie Hamilton
IPC分类号： A61N2/00
CPC分类号： A61N1/0541 , A61N1/0543
摘要： A system for movement in a body and performing a function on the body. The system comprises a polymer body portion, an electronic unit carried by the polymer body portion, a circuit in the polymer body portion operatively connected to the electronic unit, pieces in the polymer body portion, and a system for controlling movement of the polymer body portion utilizing magnetic forces controlling movement of the pieces. The system utilizes magnetic guidance to control movement of a polymer body portion.
摘要翻译：用于身体运动并在身体上执行功能的系统。该系统包括聚合物主体部分，由聚合物主体部分承载的电子单元，可操作地连接到电子单元的聚合物主体部分中的电路，聚合物主体部分中的片，以及用于控制聚合物主体部分的运动的系统利用磁力控制片的运动。该系统利用磁引导来控制聚合物主体部分的运动。

9. 发明申请

US20050136639A1 Pin-deposition of conductive inks for microelectrodes and contact via filling 有权
标题翻译：用于微电极的导电油墨的引脚沉积和通过填充的接触
公开(公告)号：US20050136639A1
公开(公告)日：2005-06-23
申请号：US10742112
申请日：2003-12-18
申请人： J. Davidson , Peter Krulevitch , Mariam Maghribi , Julie Hamilton , William Benett , Armando Tovar
发明人： J. Davidson , Peter Krulevitch , Mariam Maghribi , Julie Hamilton , William Benett , Armando Tovar
IPC分类号： H01L21/44 , H01L21/768 , H05K3/40
CPC分类号： H01L21/76838 , H05K3/4053 , H05K2203/0195 , H05K2203/0338 , Y10T29/49155
摘要： A system for metalization of an integrated microsystem. The system comprises providing a substrate and applying a conductive material to the substrate by taking up small aliquots of conductive material and releasing the conductive material onto the substrate to produce a circuit component.
摘要翻译：一个集成微系统的金属化系统。该系统包括提供衬底并且通过吸收导电材料的小等分试样并将导电材料释放到衬底上以产生电路部件而将导电材料施加到衬底。

10. 发明授权

US07756586B2 Wound healing patch with guard electrodes 有权
标题翻译：伤口愈合贴片与保护电极
公开(公告)号：US07756586B2
公开(公告)日：2010-07-13
申请号：US11876134
申请日：2007-10-22
申请人： Stuart Wenzel , Mariam Maghribi , Mark Huang
发明人： Stuart Wenzel , Mariam Maghribi , Mark Huang
IPC分类号： A61N1/04
CPC分类号： A61N1/326 , A61N1/205
摘要： In one example, the present invention is directed to a wound-healing patch including a flexible substrate, at least one wound electrode, at least one guard electrode and at least one return electrode. The guard electrode is positioned between the wound and return electrodes in the electrical path of current traveling between the return and wound electrodes on the surface of the skin, sinking the surface current and force the wound current to travel deeper into the tissue. In the invention, the wound electrode(s) is positioned on a portion of the flexible substrate designed to be placed over wounded tissue and the return electrode is positioned on a portion of the substrate substantially surrounding the wound and guard electrodes and is designed to be placed over healthy tissue.
摘要翻译：在一个实例中，本发明涉及包括柔性基底，至少一个缠绕电极，至少一个保护电极和至少一个返回电极的伤口愈合贴片。保护电极位于卷绕和返回电极之间的电路中，电流在皮肤表面的返回电极和缠绕电极之间传播，从而降低表面电流，并迫使伤口电流更深地进入组织。在本发明中，卷绕电极位于设计成放置在受伤组织上的柔性基板的一部分上，并且返回电极位于基本上围绕伤口和保护电极的基底的一部分上，并被设计为放在健康的组织上。

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