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    • 9. 发明申请
    • Anhydrous topical formulation for polyphenols
    • 无水局部用于多酚的配方
    • US20090017078A1
    • 2009-01-15
    • US10570481
    • 2004-09-21
    • Matthew BudererPeter FordGeorge RoentschRobert CervelliHeather Joyce
    • Matthew BudererPeter FordGeorge RoentschRobert CervelliHeather Joyce
    • A61K9/06A61K31/05
    • A61K9/0014A61K8/25A61K8/26A61K8/27A61K8/368A61K8/922A61K8/97A61K36/185A61K36/54A61K36/63A61K36/736A61K36/82A61K36/886A61K36/889A61K36/899A61K2800/31A61K2800/522A61Q19/00A61Q19/001A61K2300/00
    • The present invention discloses a composition of matter, and method to formulate same, which is an anhydrous topical cream, gel or ointment base, a polyphenol and a suitable adsorbent binding carrier to which the polyphenol will bind for purposes of even disbursement within the cream, gel or base and which will not inhibit the ability of the polyphenols to be released on and into the aqueous environment of the skin when the topical mixture is applied thereto. The binding carrier provides the ability to disperse a hydrophilic polyphenol in a non-aqueous medium for purposes of topical application to the body. In particular, the present invention discloses the use of polyphenols such as tea catechins, and in particular green tea catechins, disbursed in an anhydrous base consisting of either saturated or unsaturated plant oils or waxes through the use of a variety of binding carriers including, but is not limited to, talcs and clays, alginates, algae, agars, gums, gelatins, celluloses, silica, silica gels, simethicone, salicylates, silicates and silicone resins, tragacanths, calcium carbonates and magnesium or zinc oxides. Such binding carriers are particularly useful when polyphenol concentrations exceed 0.2% w/w in the mixture, and their use is preferred when concentrations are between 1.0 to 20% w/w polyphenols.
    • 本发明公开了一种物质组合物及其制备方法,其是无水局部乳膏,凝胶或软膏基质,多酚和合适的吸附剂结合载体,多酚将结合到其上以便均匀地分配在霜剂内, 凝胶或碱,并且当施用局部混合物时,其不会抑制多酚在皮肤的水性环境中释放的能力。 结合载体提供将亲水性多酚分散在非水性介质中以将其局部施用于身体的目的的能力。 特别地,本发明公开了通过使用多种结合载体,分散在由饱和或不饱和植物油或蜡组成的无水基质中的多酚如茶儿茶素,特别是绿茶儿茶素,但包括但不限于 不限于,滑石和粘土,藻酸盐,藻类,琼脂,树胶,明胶,纤维素,二氧化硅,二氧化硅凝胶,二甲硅油,水杨酸盐,硅酸盐和硅氧烷树脂,黄蓍胶,碳酸钙和镁或氧化锌。 当多酚浓度在混合物中超过0.2%w / w时,这种结合载体是特别有用的,当浓度为1.0-20%w / w多酚时优选使用它们。
    • 10. 发明申请
    • Managing packet-based telephony
    • 管理基于分组的电话
    • US20070258441A1
    • 2007-11-08
    • US11549003
    • 2006-10-12
    • Daniel GlasserPeter FordJeremy StoneBrian Daugherty
    • Daniel GlasserPeter FordJeremy StoneBrian Daugherty
    • H04L12/66
    • H04Q3/0062
    • A system for assisting a user in selecting a packet-based telephony service provider (“PBTSP”) from a group of PBTSPs, and in registering the user with the selected PBTSP for outbound and/or inbound calling. The selection of a particular PBTSP may be stored in a database, and this stored information may be used to enable the user to exchange telephone call data with one of the PBTSPs. One preferred system receives data from the user's computer device, determines whether the user is registered with one the PBTSPs and, if so, transmits data to the computer device which enables it to exchange telephone call data with one of the PBTSPs. The system also receives telephone call data from the computer device, accesses contact information for a PBTSP, and transmits the received telephone call data to the PBTSP using the accessed contact information.
    • 一种用于协助用户从一组PBTSP中选择基于分组的电话服务提供商(“PBTSP”)并且向所述用户注册所选择的PBTSP用于出站和/或呼入呼叫的系统。 特定PBTSP的选择可以存储在数据库中,并且该存储的信息可以用于使得用户能够与PBTSP之一交换电话呼叫数据。 一个优选的系统从用户的计算机设备接收数据,确定用户是否向PBTSP中的一个注册,如果是,则向计算机设备发送数据,使其能够与PBTSP之一交换电话呼叫数据。 该系统还从计算机设备接收电话呼叫数据,访问PBTSP的联系人信息,并使用所访问的联系人信息将接收的电话呼叫数据发送到PBTSP。