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1. 发明授权

US07881781B2 Thoracic impedance detection with blood resistivity compensation 有权
标题翻译：胸部阻抗检测与血液电阻率补偿
公开(公告)号：US07881781B2
公开(公告)日：2011-02-01
申请号：US12628384
申请日：2009-12-01
申请人： Jeffrey E. Stahmann , John D. Hatlestad , Boyce Moon
发明人： Jeffrey E. Stahmann , John D. Hatlestad , Boyce Moon
IPC分类号： A61B5/00
CPC分类号： A61B5/053 , A61N1/3627 , A61N1/36521
摘要： This document discusses, among other things, a cardiac rhythm management device or other implantable medical device that uses thoracic impedance to determine how much fluid is present in the thorax, such as for detecting or predicting congestive heart failure, pulmonary edema, pleural effusion, hypotension, or the like. The thoracic fluid amount determined from the thoracic impedance is compensated for changes in blood resistivity, which may result from changes in hematocrit level or other factors. The blood-resistivity-compensated thoracic fluid amount can be stored in the device or transmitted to an external device for storage or display. The blood-resistivity-compensated thoracic fluid amount can also be used to adjust a cardiac pacing, cardiac resynchronization, or other cardiac rhythm management or other therapy to the patient. This document also discusses applications of the devices and methods for predicting or indicating anemia.
摘要翻译：本文件尤其涉及一种使用胸部阻抗来确定胸部存在多少液体的心律管理装置或其他可植入医疗装置，例如用于检测或预测充血性心力衰竭，肺水肿，胸腔积液，低血压，等等。根据胸部阻抗确定的胸腔液量补偿血液电阻率的变化，这可能是血细胞比容水平的变化或其他因素引起的。血液电阻补偿的胸腔液量可以存储在设备中或者传输到外部设备进行存储或显示。血液电阻补偿的胸液量也可用于调整心脏起搏，心脏再同步或其他心律控制或对患者的其他治疗。本文件还讨论了用于预测或指示贫血的装置和方法的应用。

2. 发明授权

US07672718B2 Thoracic impedance detection with blood resistivity compensation 有权
标题翻译：胸部阻抗检测与血液电阻率补偿
公开(公告)号：US07672718B2
公开(公告)日：2010-03-02
申请号：US12139948
申请日：2008-06-16
申请人： Jeffrey E. Stahmann , John D. Hatlestad , Boyce Moon
发明人： Jeffrey E. Stahmann , John D. Hatlestad , Boyce Moon
IPC分类号： A61B5/00
CPC分类号： A61B5/053 , A61N1/3627 , A61N1/36521
摘要： This document discusses, among other things, a cardiac rhythm management device or other implantable medical device that uses thoracic impedance to determine how much fluid is present in the thorax, such as for detecting or predicting congestive heart failure, pulmonary edema, pleural effusion, hypotension, or the like. The thoracic fluid amount determined from the thoracic impedance is compensated for changes in blood resistivity, which may result from changes in hematocrit level or other factors. The blood-resistivity-compensated thoracic fluid amount can be stored in the device or transmitted to an external device for storage or display. The blood-resistivity-compensated thoracic fluid amount can also be used to adjust a cardiac pacing, cardiac resynchronization, or other cardiac rhythm management or other therapy to the patient. This document also discusses applications of the devices and methods for predicting or indicating anemia.
摘要翻译：本文件尤其涉及一种使用胸部阻抗来确定胸部存在多少液体的心律管理装置或其他可植入医疗装置，例如用于检测或预测充血性心力衰竭，肺水肿，胸腔积液，低血压，等等。根据胸部阻抗确定的胸腔液量补偿血液电阻率的变化，这可能是血细胞比容水平的变化或其他因素引起的。血液电阻补偿的胸腔液量可以存储在设备中或者传输到外部设备进行存储或显示。血液电阻补偿的胸液量也可用于调整心脏起搏，心脏再同步或其他心律控制或对患者的其他治疗。本文件还讨论了用于预测或指示贫血的装置和方法的应用。

3. 发明授权

US08200326B2 Calibration of impedance monitoring of respiratory volumes using thoracic D.C. impedance 有权
标题翻译：使用胸部直流阻抗校正阻抗监测呼吸体积
公开(公告)号：US08200326B2
公开(公告)日：2012-06-12
申请号：US12557372
申请日：2009-09-10
申请人： John D. Hatlestad , Loell Boyce Moon , Jesse W. Hartley , Jeffrey E. Stahmann
发明人： John D. Hatlestad , Loell Boyce Moon , Jesse W. Hartley , Jeffrey E. Stahmann
IPC分类号： A61B5/05 , A61B5/08
CPC分类号： A61N1/36521 , A61B5/0809 , A61B2560/0223 , A61N1/3756
摘要： A system includes an implantable medical device that includes a trans-thoracic impedance measurement circuit providing a trans-thoracic impedance signal of a subject. A controller is coupled to the trans-thoracic impedance circuit. The controller extracts a respiration signal from the trans-thoracic impedance signal, measures a breathing volume of the subject using the amplitude of the respiration signal and a breathing volume calibration factor, computes an adjusted breathing volume calibration factor using a reference baseline value of the trans-thoracic impedance and a measured baseline value of the trans-thoracic impedance, and computes a calibrated breathing volume using the adjusted breathing volume calibration factor.
摘要翻译：一种系统包括可植入医疗装置，其包括提供受试者的胸部阻抗信号的跨胸阻抗测量电路。控制器耦合到跨胸阻抗电路。控制器从胸部阻抗信号中提取呼吸信号，使用呼吸信号的幅度和呼吸音量校准因子来测量受试者的呼吸体积，使用反式信号的参考基准值计算调整后的呼吸量校准因子胸廓阻抗和经胸阻抗的测量基线值，并使用调整后的呼吸量校准因子计算校准呼吸量。

4. 发明授权

US08915741B2 Sleep quality data collection and evaluation 有权
标题翻译：睡眠质量数据收集和评估
公开(公告)号：US08915741B2
公开(公告)日：2014-12-23
申请号：US13215592
申请日：2011-08-23
申请人： John D. Hatlestad , Quan Ni , Jeffrey E. Stahmann , Jesse Hartley , Qingsheng Zhu , Bruce H. KenKnight , Douglas R. Daum , Kent Lee
发明人： John D. Hatlestad , Quan Ni , Jeffrey E. Stahmann , Jesse Hartley , Qingsheng Zhu , Bruce H. KenKnight , Douglas R. Daum , Kent Lee
IPC分类号： G09B23/28 , A61B5/0205 , A61B5/00 , A61B5/0488 , A61B5/11 , A61B5/0476 , A61N1/362 , A61B5/08 , A61B5/0496
CPC分类号： A61B5/4815 , A61B5/0031 , A61B5/0205 , A61B5/0476 , A61B5/0488 , A61B5/0496 , A61B5/0809 , A61B5/11 , A61B5/4528 , A61B5/4818 , A61N1/3621 , G06F19/00
摘要： A sleep quality assessment approach involves collecting data based on detected physiological or non-physiological patient conditions. At least one of detecting patient conditions and collecting data is performed using an implantable device. Sleep quality may be evaluated using the collected data by an implantable or patient-external sleep quality processor. One approach to sleep quality evaluation involves computing one or more summary metrics based on occurrences of movement disorders or breathing disorders during sleep.
摘要翻译：睡眠质量评估方法包括基于检测到的生理或非生理性患者状况收集数据。使用可植入装置执行检测患者状况和收集数据中的至少一个。可以使用可植入或患者外部的睡眠质量处理器收集的数据来评估睡眠质量。睡眠质量评估的一种方法包括基于睡眠期间的运动障碍或呼吸障碍的发生来计算一个或多个总结度量。

5. 发明申请

US20110061647A1 Patient Monitoring, Diagnosis, And/Or Therapy Systems and Methods 审中-公开
标题翻译：患者监测，诊断和/或治疗系统和方法
公开(公告)号：US20110061647A1
公开(公告)日：2011-03-17
申请号：US12872730
申请日：2010-08-31
申请人： Jeffrey E. Stahmann , Kent Lee , Jesse W. Hartley , Quan Ni , John D. Hatlestad , Qingsheng Zhu , Krzysztof Z. Siejko
发明人： Jeffrey E. Stahmann , Kent Lee , Jesse W. Hartley , Quan Ni , John D. Hatlestad , Qingsheng Zhu , Krzysztof Z. Siejko
IPC分类号： A61M16/00
CPC分类号： A61B5/4818 , A61B5/0031 , A61B5/02055 , A61B5/0215 , A61B5/02405 , A61B5/0421 , A61B5/0422 , A61B5/0464 , A61B5/0476 , A61B5/0488 , A61B5/0496 , A61B5/053 , A61B5/0809 , A61B5/0836 , A61B5/087 , A61B5/103 , A61B5/1116 , A61B5/113 , A61B5/145 , A61B5/14539 , A61B5/14542 , A61B5/4035 , A61B5/4519 , A61B5/6814 , A61B5/6823 , A61B5/6828 , A61B5/686 , A61B5/6891 , A61B5/7275 , A61B7/00 , A61B2562/0219 , A61M16/0051 , A61M16/026 , A61M16/0666 , A61M16/10 , A61M2016/0021 , A61M2016/0036 , A61M2016/0039 , A61M2016/0042 , A61M2202/0208 , A61M2205/3303 , A61M2205/3306 , A61M2205/3375 , A61M2205/3561 , A61M2205/3592 , A61M2205/52 , A61M2230/04 , A61M2230/10 , A61M2230/202 , A61M2230/205 , A61M2230/30 , A61M2230/432 , A61M2230/435 , A61M2230/50 , A61M2230/60 , A61M2230/63 , A61M2230/65 , A61N1/3601 , A61N1/362 , A61N1/3627 , A61N1/365 , A61N1/36514 , A61N1/36535 , A61N1/36557 , A61N1/36578 , A61N1/36585 , A61N1/36592 , A61N1/37 , G16H20/30 , G16H20/40 , G16H50/20
摘要： Systems and methods involve an implantable device configured to perform at least one cardiac-related function, a patient-external respiratory therapy device, and a communication channel configured to facilitate communication between the implantable device and the respiratory therapy device. The implantable and respiratory therapy devices operate cooperatively via the communication channel to provide one or more of patient monitoring, diagnosis, and therapy. The communication channel may be configured to facilitate communication between an external processing system and at least one of the implantable device and the respiratory therapy device. The processing system is communicatively coupled to at least one of the implantable and respiratory therapy devices via the communication channel to provide one or more of patient monitoring, diagnosis, and therapy.
摘要翻译：系统和方法涉及被配置为执行至少一个心脏相关功能的可植入装置，患者外部呼吸治疗装置和被配置为促进可植入装置和呼吸治疗装置之间的通信的通信信道。可植入和呼吸治疗装置通过通信通道协同工作，以提供患者监测，诊断和治疗中的一个或多个。通信信道可以被配置为促进外部处理系统与至少一个可植入装置和呼吸治疗装置之间的通信。处理系统经由通信信道通信地耦合到可植入和呼吸治疗装置中的至少一个，以提供患者监测，诊断和治疗中的一个或多个。

6. 发明申请

US20090118627A1 SYSTEM AND METHOD FOR EVALUATING CARDIAC PERFORMANCE RELATIVE TO PERFORMANCE OF AN INTRATHORACIC PRESSURE MANEUVER 审中-公开
标题翻译：相对于静脉压力管理器的性能评估心脏性能的系统和方法
公开(公告)号：US20090118627A1
公开(公告)日：2009-05-07
申请号：US12349413
申请日：2009-01-06
申请人： Jeffrey E. Stahmann , Donald L. Hopper , Veerichetty Kadhiresan , John D. Hatlestad
发明人： Jeffrey E. Stahmann , Donald L. Hopper , Veerichetty Kadhiresan , John D. Hatlestad
IPC分类号： A61B5/0215
CPC分类号： A61B7/00 , A61B5/021
摘要： A system and method for evaluating cardiac performance relative to performance of an intrathoracic pressure maneuver is described. Blood pressure is indirectly sensed by directly collecting intracardiac impedance measures through an implantable medical device. Cardiac functional changes to the blood pressure are evaluated in response to performance of an intrathoracic pressure maneuver.
摘要翻译：描述了相对于胸内压力操作的性能来评估心脏性能的系统和方法。通过直接通过可植入医疗装置收集心内阻塞措施间接检测血压。根据胸腔内压力机动的性能评估对血压的心脏功能变化。

7. 发明授权

US07488290B1 System and method for assessing cardiac performance through transcardiac impedance monitoring 有权
标题翻译：通过心跳阻抗监测评估心脏性能的系统和方法
公开(公告)号：US07488290B1
公开(公告)日：2009-02-10
申请号：US10782642
申请日：2004-02-19
申请人： Jeffrey E. Stahmann , Donald L. Hopper , Veerichetty Kadhiresan , John D. Hatlestad
发明人： Jeffrey E. Stahmann , Donald L. Hopper , Veerichetty Kadhiresan , John D. Hatlestad
IPC分类号： A61B5/00
CPC分类号： A61B7/00 , A61B5/021
摘要： A system and method for assessing cardiac performance through transcardiac impedance monitoring is described. Intracardiac impedance measures are directly collected through an implantable medical device. The intracardiac impedance measures are correlated to cardiac dimensional measures relative to performance of an intrathoracic pressure maneuver. The cardiac dimensional measures are grouped into at least one measures set corresponding to a temporal phase of the intrathoracic pressure maneuver. The at least one cardiac dimensional measures set is evaluated against a cardiac dimensional trend for the corresponding intrathoracic pressure maneuver temporal phase to represent cardiac performance.
摘要翻译：描述了通过心跳阻抗监测来评估心脏性能的系统和方法。通过植入式医疗设备直接收集心内阻塞措施。心内阻抗测量与胸腔内压力操作性能相关的心脏尺寸测量值相关。心脏尺寸测量被分组为对应于胸内压力操纵的时间相位的至少一个测量组。针对相应的胸内压力机动时间阶段的心脏尺寸趋势来评估至少一个心脏尺寸测量集合以表示心脏性能。

8. 发明授权

US08323204B2 Medical event logbook system and method 有权
标题翻译：医疗事件日志系统和方法
公开(公告)号：US08323204B2
公开(公告)日：2012-12-04
申请号：US12403880
申请日：2009-03-13
申请人： Jeffrey E. Stahmann , John D. Hatlestad , Jesse W. Hartley , Quan Ni , Kent Lee
发明人： Jeffrey E. Stahmann , John D. Hatlestad , Jesse W. Hartley , Quan Ni , Kent Lee
IPC分类号： A61B5/08 , A61B5/02
CPC分类号： A61B5/0803 , A61B5/02405 , A61N1/3601
摘要： An event-based approach to collecting and organizing information associated with events affecting respiration is presented. The detection or prediction of an event affecting the respiration of a patient initiates acquisition of information associated with the event. The respiratory logbook system acquires information associated with the event during the event and during intervals proximate in time to the event. The information is organized as a respiratory log entry. The user can access the information by operating a user interface. The information may be presented in textual or graphical form.
摘要翻译：提出了一种基于事件的方法来收集和组织与影响呼吸的事件相关的信息。影响患者呼吸的事件的检测或预测启动与事件相关联的信息的获取。呼吸记录系统在事件期间以及在时间上接近事件的间隔期间获取与事件相关联的信息。信息被组织为呼吸日志条目。用户可以通过操作用户界面访问信息。信息可以以文本或图形形式呈现。

9. 发明授权

US08002553B2 Sleep quality data collection and evaluation 有权
公开(公告)号：US08002553B2
公开(公告)日：2011-08-23
申请号：US10642998
申请日：2003-08-18
申请人： John D. Hatlestad , Quan Ni , Jeffrey E. Stahmann , Jesse Hartley , Qingsheng Zhu , Bruce H. Kenknight , Douglas R. Daum , Kent Lee
发明人： John D. Hatlestad , Quan Ni , Jeffrey E. Stahmann , Jesse Hartley , Qingsheng Zhu , Bruce H. Kenknight , Douglas R. Daum , Kent Lee
IPC分类号： G09B23/28
CPC分类号： A61B5/4815 , A61B5/0031 , A61B5/0205 , A61B5/0476 , A61B5/0488 , A61B5/0496 , A61B5/0809 , A61B5/11 , A61B5/4528 , A61B5/4818 , A61N1/3621 , G06F19/00
摘要： A sleep quality assessment approach involves collecting data based on detected physiological or non-physiological patient conditions. At least one of detecting patient conditions and collecting data is performed using an implantable device. Sleep quality may be evaluated using the collected data by an implantable or patient-external sleep quality processor. One approach to sleep quality evaluation involves computing one or more summary metrics based on occurrences of movement disorders or breathing disorders during sleep.

10. 发明授权

US07983745B2 Advanced patient management with environmental data 有权
标题翻译：高级患者管理与环境数据
公开(公告)号：US07983745B2
公开(公告)日：2011-07-19
申请号：US12350875
申请日：2009-01-08
申请人： John D. Hatlestad , Jeffrey E. Stahmann , Qingsheng Zhu
发明人： John D. Hatlestad , Jeffrey E. Stahmann , Qingsheng Zhu
IPC分类号： A61N1/00
CPC分类号： A61B5/0031 , A61B5/0022 , A61B5/0205 , A61B5/0537 , A61B5/0816 , A61B5/091 , A61B5/1118 , A61B7/04 , A61B2560/0247 , A61B2560/0252 , A61B2560/0257 , A61N1/37252 , A61N1/37282 , G06F19/00 , G06F19/3418 , G16H40/63 , G16H50/30
摘要： Systems, devices and methods for using environmental data to manage health care are disclosed. One aspect is an advanced patient management system. In various embodiments, the system includes at least one implantable medical device (IMD) to acquire at least one IMD parameter indicative of patient wellness, means to acquire at least one environmental parameter from at least one external source, and means to correlate the at least one parameter indicative of patient wellness and the at least one environmental parameter to assist with patient health care decisions. Other aspects and embodiments are provided herein.
摘要翻译：公开了使用环境数据来管理医疗保健的系统，设备和方法。一个方面是先进的患者管理系统。在各种实施例中，系统包括至少一个可植入医疗装置（IMD），以获取指示患者健康的至少一个IMD参数，从至少一个外部源获取至少一个环境参数的手段，以及至少将指示患者健康的一个参数和用于协助患者医疗保健决定的至少一个环境参数。本文提供了其它方面和实施例。

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