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1. 发明申请

US20150224113A1 6-(5-HYDROXY-1H-PYRAZOL-1-YL)NICOTINAMIDE INHIBITORS OF PHD 有权
标题翻译： 6-（5-羟基-1H-吡唑-1-基）尼泊苷抑制剂
公开(公告)号：US20150224113A1
公开(公告)日：2015-08-13
申请号：US14693110
申请日：2015-04-22
申请人： Jason W. Brown , Melinda Davis , Anthony Ivetac , Benjamin Jones , Andre A. Kiryanov , Jon Kuehler , Marion Lanier , Joanne Miura , Sean Murphy , Xiaolun Wang
发明人： Jason W. Brown , Melinda Davis , Anthony Ivetac , Benjamin Jones , Andre A. Kiryanov , Jon Kuehler , Marion Lanier , Joanne Miura , Sean Murphy , Xiaolun Wang
IPC分类号： A61K31/5513 , A61K31/4985 , A61K31/5377 , A61K31/496 , A61K31/444 , A61K31/4545
CPC分类号： C07D401/14 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/551 , A61K31/5513 , C07D401/04 , C07D405/14 , C07D413/14 , C07D417/14 , C07D471/08 , C07D487/04 , C07D487/06 , C07D487/10 , C07D491/10 , C07D491/107
摘要： The present invention provides a method of treating acute heart failure by administering a compound of the formula: or a pharmaceutically acceptable salt thereof.
摘要翻译：本发明提供了通过给予下式化合物或其药学上可接受的盐治疗急性心力衰竭的方法。

2. 发明申请

US20200277262A1 N-(CYANO-SUBSTITUTED BENZYL OR PYRIDINYLMETHYL)-3-HYDROXYPICOLINAMIDE DERIVATIVES 审中-公开
公开(公告)号：US20200277262A1
公开(公告)日：2020-09-03
申请号：US16650858
申请日：2018-09-24
申请人： Benjamin Jones , Andre Kiryanov , Jon Kuehler , Marion Lanier , Sean Murphy , Feng Zhou , Takeda Pharmaceutical Company Limited
发明人： Benjamin Jones , Andre Kiryanov , Jon Kuehler , Marion Lanier , Sean Murphy , Feng Zhou
IPC分类号： C07D213/81
摘要： Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein R3, R4, R5, R6, R7, R8, R9, X1 and X2 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating diseases, disorders, and conditions associated with PHD.

3. 发明授权

US08336664B2 Telematics basic mobile device safety interlock 有权
标题翻译：远程信息处理基础移动设备安全互锁
公开(公告)号：US08336664B2
公开(公告)日：2012-12-25
申请号：US12926582
申请日：2010-11-29
申请人： Erik Wallace , Drew Morin , Lance D. Pitt , Sean Murphy
发明人： Erik Wallace , Drew Morin , Lance D. Pitt , Sean Murphy
IPC分类号： B60K28/02 , H04K3/00
CPC分类号： H04M1/67 , H04M1/6091 , H04M1/7253 , H04M1/72552 , H04M2250/02 , Y02D70/1262 , Y02D70/144 , Y02D70/146 , Y02D70/164 , Y02D70/23
摘要： A vehicle includes a telematics controller and a single short range, low power interior transmitter focused substantially only on a vehicle's driver's seat only. Synergistic interaction is provided between a vehicle's telematics controller and a wireless device used by the driver (e.g. a cell phone, smart phone, PDA, wireless laptop, etc.) to parametrically control at least one wireless service or other operation of a wireless device presumed operated by the driver of the vehicle. Example wireless services blocked or forced into a safe mode (such as hands-free operation) include SMS, Email, and Voice services.
摘要翻译：车辆包括远程信息处理控制器和仅基于车辆驾驶员座椅的单个短距离低功率内部发射器。在车辆远程信息处理控制器和驾驶员使用的无线设备（例如，手机，智能电话，PDA，无线笔记本电脑等）之间提供协同互动，以参数地控制至少一个无线服务或推定的无线设备的其他操作由车辆司机操作。阻止或强制进入安全模式（如免提操作）的示例包括短信，电子邮件和语音服务。

4. 发明申请

US20060201028A1 Mechanical cushioning system for footwear 有权
标题翻译：鞋类机械缓冲系统
公开(公告)号：US20060201028A1
公开(公告)日：2006-09-14
申请号：US11077327
申请日：2005-03-10
申请人： Marya Chan , Patrick Choe , David Dirsa , Edith Harmon-Weiss , Sean Murphy
发明人： Marya Chan , Patrick Choe , David Dirsa , Edith Harmon-Weiss , Sean Murphy
IPC分类号： A43B13/18 , A43B13/12
CPC分类号： A43B7/142 , A43B13/141 , A43B13/16 , A43B13/186 , A43B21/26 , A43B21/32
摘要： A midsole for footwear comprising a midsole element, which comprises a top plate, a bottom plate, and a plurality of strut members disposed between the top and bottom plates for supporting the top plate a distance away from the bottom plate. Adjacent strut members have a C shaped cross-section facing in the same direction. The midsole element may further comprise a heel cleft to increase the flexibility of the sole. In a preferred embodiment, the strut members on the medial side are arranged at an angle to the strut members on the lateral side of the sole. The directional design provides flexibility and stiffness anisotropically to the sole in the longitudinal and lateral directions of the sole respectively.
摘要翻译：一种用于鞋类的中底，其包括中底元件，其包括顶板，底板和设置在顶板和底板之间的多个支柱构件，用于将顶板支撑离开底板一定距离。相邻的支柱构件具有朝向相同方向的C形横截面。鞋底夹层元件还可以包括鞋跟裂缝以增加鞋底的柔性。在优选实施例中，内侧上的支柱构件与鞋底侧面上的支柱构件成一定角度布置。方向设计分别在鞋底的纵向和横向上各向异性地提供鞋底的柔性和刚度。

5. 发明申请

US20120006611A1 Telematics basic mobile device safety interlock 有权
公开(公告)号：US20120006611A1
公开(公告)日：2012-01-12
申请号：US12926582
申请日：2010-11-29
申请人： Erik Wallace , Drew Morin , Lance D. Pitt , Sean Murphy
发明人： Erik Wallace , Drew Morin , Lance D. Pitt , Sean Murphy
IPC分类号： B60K28/02
CPC分类号： H04M1/67 , H04M1/6091 , H04M1/7253 , H04M1/72552 , H04M2250/02 , Y02D70/1262 , Y02D70/144 , Y02D70/146 , Y02D70/164 , Y02D70/23
摘要： A vehicle includes a telematics controller and a single short range, low power interior transmitter focused substantially only on a vehicle's driver's seat only. Synergistic interaction is provided between a vehicle's telematics controller and a wireless device used by the driver (e.g. a cell phone, smart phone, PDA, wireless laptop, etc.) to parametrically control at least one wireless service or other operation of a wireless device presumed operated by the driver of the vehicle. Example wireless services blocked or forced into a safe mode (such as hands-free operation) include SMS, Email, and Voice services.

6. 发明申请

US20120006610A1 Telematics enhanced mobile device safety interlock 审中-公开
标题翻译：远程信息处理增强了移动设备安全互锁
公开(公告)号：US20120006610A1
公开(公告)日：2012-01-12
申请号：US12926581
申请日：2010-11-29
申请人： Erik Wallace , Drew Morin , Lance D. Pitt , Sean Murphy
发明人： Erik Wallace , Drew Morin , Lance D. Pitt , Sean Murphy
IPC分类号： B60K28/02
CPC分类号： H04M1/67 , H04M1/6091 , H04M1/7253 , H04M1/72552 , H04M2250/02 , Y02D70/1262 , Y02D70/144 , Y02D70/146 , Y02D70/164 , Y02D70/23
摘要： A vehicle includes a telematics controller and at least three short range, low power interior transceivers, one of which is focused on a vehicle's driver's seat only. At least two additional individual short range, low power interior transceivers are focused on a front passenger seat, and a rear seat. A fourth or more short range, low power interior transceiver may be included in a larger vehicle. Synergistic interaction is provided between a vehicle's telematics controller and wireless devices (e.g. cell phones, smart phones, PDAs, wireless laptops, etc.) to parametrically control at least one wireless service or other operation of a wireless device presumed operated by the driver of the vehicle. Example wireless services blocked or forced into a safe mode (such as hands-free operation) include SMS, Email, and Voice services.
摘要翻译：车辆包括远程信息处理控制器和至少三个短距离低功率内部收发器，其中一个专注于车辆的驾驶员座椅。至少另外两个单独的短距离，低功率内部收发器集中在前排乘客座椅和后座椅上。第四个或更多的短距离低功率内部收发器可以被包括在较大的车辆中。在车辆远程信息处理控制器和无线设备（例如，蜂窝电话，智能电话，PDA，无线笔记本电脑等）之间提供协同互动，以参数地控制由驾驶员假定的无线设备的至少一个无线服务或其他操作车辆。阻止或强制进入安全模式（如免提操作）的示例包括短信，电子邮件和语音服务。

7. 发明授权

US07865210B2 Ejectable component assemblies in electronic devices 有权
标题翻译：电子设备中的可弹性组件
公开(公告)号：US07865210B2
公开(公告)日：2011-01-04
申请号：US11824032
申请日：2007-06-28
申请人： Erik L. Wang , Sean Murphy , Tang Yew Tan , Jeffrey Eugene Neaves , Lawrence E. Davis , Sung Kim
发明人： Erik L. Wang , Sean Murphy , Tang Yew Tan , Jeffrey Eugene Neaves , Lawrence E. Davis , Sung Kim
IPC分类号： H04M1/00
CPC分类号： H04M1/026 , H04M2250/14 , H05K1/02 , H05K5/0295 , H05K7/1405 , H05K7/1427
摘要： Electronic devices are provided with ejectable component assemblies that can be substantially flush with the external surfaces of the housings of the devices, despite variations in their manufacture. The ejectable component assemblies may include connectors coupled to circuit boards of the devices, and trays that can be loaded with removable modules, inserted through openings in the housings of the devices, and into the connectors for functionally aligning the removable modules with the circuit boards. The ejectable component assemblies may also include ejectors coupled to the housings of the devices for ejecting the trays from the connectors and, thus, from the devices themselves.
摘要翻译：电子设备设置有可排出的部件组件，其可以与设备的壳体的外表面基本齐平，尽管其制造方面有变化。可喷射部件组件可以包括连接到设备的电路板的连接器，以及可以装载有通过设备壳体中的开口插入的可移除模块的托盘，并且用于将可拆卸模块与电路板功能对准。可喷射部件组件还可以包括联接到装置的壳体的喷射器，用于从连接器弹出托盘，并且因此从装置本身排出托盘。

8. 发明申请

US20100126040A1 Mechanical cushioning system for footwear 有权
标题翻译：鞋类机械缓冲系统
公开(公告)号：US20100126040A1
公开(公告)日：2010-05-27
申请号：US12590050
申请日：2009-11-02
申请人： Paul S. Grote , Patrick Y. Choe , Sean Murphy
发明人： Paul S. Grote , Patrick Y. Choe , Sean Murphy
IPC分类号： A43B13/18
CPC分类号： A43B7/24 , A43B13/181
摘要： A midsole element is adapted for positioning on a medial or lateral side of a shoe. The midsole element, having a longitudinal direction and a transverse direction, includes a top portion, a bottom portion, and a compression element, which has at least two first strut members and at least two second strut members disposed between the top and bottom portions and supporting the top portion a distance away from the bottom portion. The at least two first strut members being separated by a first longitudinal distance in the longitudinal direction. The at least two second strut members being separated by a second longitudinal distance in the longitudinal direction and each of said first and second transversely disposed two strut members are oriented and adapted to preferentially deflect in the same direction in response to a force imparted on the midsole element.
摘要翻译：中底元件适于定位在鞋的内侧或外侧上。具有纵向和横向的中底元件包括顶部，底部和压缩元件，其具有至少两个第一支柱构件和设置在顶部和底部之间的至少两个第二支柱构件，以及支撑顶部距离底部一定距离。所述至少两个第一支柱构件在纵向方向上分开第一纵向距离。所述至少两个第二支柱构件在纵向方向上被第二纵向距离分开，并且所述第一和第二横向布置的两个支柱构件中的每一个被定向并适于响应于施加在中底上的力而在相同方向上优先偏转元件。

9. 发明申请

US20050119231A1 Quinolone antibacterial agents 审中-公开
标题翻译：喹诺酮抗菌剂
公开(公告)号：US20050119231A1
公开(公告)日：2005-06-02
申请号：US10936223
申请日：2004-09-08
申请人： Edmund Ellsworth , Kim Hutchings , Timothy Kuss , Sean Murphy , Sharon Powell , Richard Sciotti , Jeremy Starr , Tuan Tran
发明人： Edmund Ellsworth , Kim Hutchings , Timothy Kuss , Sean Murphy , Sharon Powell , Richard Sciotti , Jeremy Starr , Tuan Tran
IPC分类号： A61K31/517 , A61K31/519 , A61K31/675 , A61P31/04 , C07D403/04 , C07D405/14 , C07D413/14 , C07D417/14 , C07D471/04
CPC分类号： C07D403/04 , C07D405/14 , C07D413/14 , C07D417/14 , C07D471/04
摘要： Compounds of formula I and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula I as well as pharmaceutically acceptable compositions comprising compounds of formula I. Compounds of formula I as disclosed herein can be used in a variety of applications including use as antibacterial agents.
摘要翻译：公开了式I化合物及其制备方法。还公开了制备式I的生物活性化合物的方法以及包含式I化合物的药学上可接受的组合物的方法。本文公开的式I化合物可用于多种应用，包括用作抗菌剂。

10. 发明申请

US20050096297A1 Antibacterial agents 审中-公开
标题翻译：抗菌剂
公开(公告)号：US20050096297A1
公开(公告)日：2005-05-05
申请号：US10936209
申请日：2004-09-08
申请人： Edmund Ellsworth , Kim Hutchings , Sean Murphy , Sharon Powell , Richard Sciotti , Tuan Tran
发明人： Edmund Ellsworth , Kim Hutchings , Sean Murphy , Sharon Powell , Richard Sciotti , Tuan Tran
IPC分类号： A61K31/4709 , A61K31/4745 , A61K31/69 , A61P31/04 , C07D401/04 , C07D401/14 , C07D471/02 , C07D471/04 , C07F5/02 , C07D43/02
CPC分类号： C07D471/04 , C07D401/04 , C07D401/14
摘要： Compounds of formula I and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula I as well as pharmaceutically acceptable compositions comprising compounds of formula I. Compounds of formula I as disclosed herein can be used in a variety of applications including use as antibacterial agents.
摘要翻译：公开了式I化合物及其制备方法。还公开了制备式I的生物活性化合物的方法以及包含式I化合物的药学上可接受的组合物的方法。本文公开的式I化合物可用于多种应用，包括用作抗菌剂。

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