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1. 发明授权

US07335725B2 Lipopeptides as antibacterial agents 有权
标题翻译：脂肽作为抗菌剂
公开(公告)号：US07335725B2
公开(公告)日：2008-02-26
申请号：US11121851
申请日：2005-05-04
申请人： Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xian Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
发明人： Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xian Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
IPC分类号： C07K7/50
CPC分类号： C07K7/08 , A61K38/00
摘要： The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
摘要翻译：本发明涉及新型脂肽化合物。本发明还涉及这些化合物的药物组合物和使用这些化合物作为抗菌化合物的方法。本发明还涉及生产这些新型脂肽化合物的方法和用于生产这些化合物的中间体。

2. 发明授权

US06911525B2 Lipopeptides as antibacterial agents 有权
标题翻译：脂肽作为抗菌剂
公开(公告)号：US06911525B2
公开(公告)日：2005-06-28
申请号：US09738742
申请日：2000-12-15
申请人： Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xian Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
发明人： Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xian Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
IPC分类号： A61K45/00 , A61K38/00 , A61P31/04 , C07K1/06 , C07K7/08 , C07K7/50
CPC分类号： C07K7/08 , A61K38/00
摘要： The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
摘要翻译：本发明涉及新型脂肽化合物。本发明还涉及这些化合物的药物组合物和使用这些化合物作为抗菌化合物的方法。本发明还涉及生产这些新型脂肽化合物的方法和用于生产这些化合物的中间体。

3. 发明授权

US06794490B2 Lipopeptides as antibacterial agents 有权
标题翻译：脂肽作为抗菌剂
公开(公告)号：US06794490B2
公开(公告)日：2004-09-21
申请号：US09739535
申请日：2000-12-15
申请人： Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xian Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
发明人： Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xian Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
IPC分类号： A61K3812
CPC分类号： C07K7/08 , A61K38/00
摘要： The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
摘要翻译：本发明涉及新型脂肽化合物。本发明还涉及这些化合物的药物组合物和使用这些化合物作为抗菌化合物的方法。本发明还涉及生产这些新型脂肽化合物的方法和用于生产这些化合物的中间体。

4. 发明授权

US07408025B2 Lipopeptides as antibacterial agents 有权
公开(公告)号：US07408025B2
公开(公告)日：2008-08-05
申请号：US09737908
申请日：2000-12-15
申请人： Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xiang Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
发明人： Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xiang Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
IPC分类号： C07K7/50
CPC分类号： C07K7/08 , A61K38/00
摘要： The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.

5. 发明申请

US20090011977A1 Novel Lipopeptides as Antibacterial Agents 审中-公开
标题翻译：新型脂肽作为抗菌剂
公开(公告)号：US20090011977A1
公开(公告)日：2009-01-08
申请号：US12163225
申请日：2008-06-27
申请人： Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xiang Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
发明人： Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xiang Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
IPC分类号： A61K38/12 , C07K7/64
CPC分类号： C07K7/08 , A61K38/00
摘要： The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
摘要翻译：本发明涉及新型脂肽化合物。本发明还涉及这些化合物的药物组合物和使用这些化合物作为抗菌化合物的方法。本发明还涉及生产这些新型脂肽化合物的方法和用于生产这些化合物的中间体。

6. 发明申请

US20080287347A1 Novel Lipopeptides as Antibacterial Agents 审中-公开
标题翻译：新型脂肽作为抗菌剂
公开(公告)号：US20080287347A1
公开(公告)日：2008-11-20
申请号：US12163299
申请日：2008-06-27
申请人： Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xiang Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
发明人： Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xiang Yang Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan D. Watson , Yan Zhang
IPC分类号： A61K38/12 , C07K7/54 , A61P31/04
CPC分类号： C07K7/08 , A61K38/00
摘要： The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
摘要翻译：本发明涉及新型脂肽化合物。本发明还涉及这些化合物的药物组合物和使用这些化合物作为抗菌化合物的方法。本发明还涉及生产这些新型脂肽化合物的方法和用于生产这些化合物的中间体。

7. 发明申请

US20050203006A1 Novel lipopeptides as antibacterial agents 有权
标题翻译：新型脂肽作为抗菌剂
公开(公告)号：US20050203006A1
公开(公告)日：2005-09-15
申请号：US11121851
申请日：2005-05-04
申请人： Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xian Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan Watson , Yan Zhang
发明人： Jason Hill , Ian Parr , Michael Morytko , Jim Siedlecki , Xian Yu , Jared Silverman , Dennis Keith , John Finn , Dale Christensen , Tsvetelina Lazarova , Alan Watson , Yan Zhang
IPC分类号： A61K45/00 , A61K38/00 , A61P31/04 , C07K1/06 , C07K7/08 , A61K38/12 , C07K7/64
CPC分类号： C07K7/08 , A61K38/00
摘要： The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
摘要翻译：本发明涉及新型脂肽化合物。本发明还涉及这些化合物的药物组合物和使用这些化合物作为抗菌化合物的方法。本发明还涉及生产这些新型脂肽化合物的方法和用于生产这些化合物的中间体。

8. 发明授权

US06397772B1 Boat motor trolling attachment 失效
标题翻译：船电机拖钓附件
公开(公告)号：US06397772B1
公开(公告)日：2002-06-04
申请号：US09543494
申请日：2000-04-06
申请人： Dale Christensen
发明人： Dale Christensen
IPC分类号： B63H2544
CPC分类号： B63H20/34 , B63H25/44
摘要： The present invention discloses a boat motor trolling attachment for use in conjunction with a boat motor and propeller to achieve effective trolling speeds. The boat motor trolling attachment includes a frame, defining an opening, and attached to a mounting bracket which is secured to the boat motor. Two springs are attached between the frame and the mounting bracket so as to bias the frame into a trolling position wherein the frame is disposed in a plane perpendicular to an axis defined by the propeller. Four control members are disposed horizontally across the opening and rotatably fixed to the frame so that a outflow of water impinging on the control members when the boat motor is in a forward gear automatically causes the control members to rotate in the frame so as to substantially close off the opening and form a continuous surface. The outflow of water generated by the propeller acts on the continuous surface and is transmitted thereby to the boat so as to resist forward motion of the boat. When the boat motor is in a reverse gear, the control members automatically rotate to allow a inflow of water to be generated by the propeller thereby facilitating control and maneuverability of the boat in reverse. At high forward speeds, the outflow of water generated by the propeller overcomes the bias imposed on the frame by the springs and automatically moves the frame to an inoperative position wherein the frame is disposed in a plane substantially parallel to the axis defined by the propeller.
摘要翻译：本发明公开了一种用于与船用电动机和螺旋桨结合使用以实现有效牵引速度的船用电动机拖钓附件。船用马达拖钓附件包括框架，其限定开口，并且附接到固定到船用马达的安装支架。两个弹簧连接在框架和安装支架之间，以便将框架偏置成拖曳位置，其中框架设置在垂直于由螺旋桨限定的轴线的平面内。四个控制构件水平地布置在开口上并且可旋转地固定到框架上，使得当船电机处于前进档时撞击在控制构件上的水的流出自动地使得控制构件在框架中旋转以便基本上闭合打开开口并形成连续的表面。由螺旋桨产生的水的流出作用在连续的表面上并由此传递给船，以阻止船的向前运动。当船用电机处于倒档时，控制构件自动旋转以允许由螺旋桨产生的水的流入，从而有助于船的控制和机动性相反。在高前进速度下，由螺旋桨产生的水的流出克服了由弹簧施加在框架上的偏压，并且自动地将框架移动到非工作位置，其中框架设置在基本上平行于由螺旋桨限定的轴线的平面中。

9. 发明申请

US20100258658A1 Water outlet coupler 审中-公开
标题翻译：出水口
公开(公告)号：US20100258658A1
公开(公告)日：2010-10-14
申请号：US12384859
申请日：2009-04-09
申请人： Dale Christensen , John Kastl , Ricky D. McGee , Dennis R. Theilen
发明人： Dale Christensen , John Kastl , Ricky D. McGee , Dennis R. Theilen
IPC分类号： B05B3/00 , F16L39/02
CPC分类号： F16L33/04 , A01G25/092 , F16L41/084 , Y10T137/9029
摘要： A coupler is provided for an irrigation system wherein the coupler is mounted in the bottom of the water supply pipe rather than at the top of the water supply pipe with the upper end of the coupler projecting sufficiently upwardly within the water supply pipe to prevent debris from entering the interior thereof. A modified form of the invention is also disclosed.
摘要翻译：提供了一种用于灌溉系统的耦合器，其中耦合器安装在供水管的底部，而不是在供水管的顶部，同时耦合器的上端在供水管中足够地向上突出，以防止碎屑进入其内部还公开了本发明的修改形式。

10. 发明申请

US20060234210A1 Filtration device and method for removing selected materials from biological fluids 审中-公开
标题翻译：用于从生物流体中去除所选材料的过滤装置和方法
公开(公告)号：US20060234210A1
公开(公告)日：2006-10-19
申请号：US11105202
申请日：2005-04-13
申请人： Daniel Kenan , Dale Christensen , Mark Grinstaff
发明人： Daniel Kenan , Dale Christensen , Mark Grinstaff
IPC分类号： C12Q1/70 , G01N33/53
CPC分类号： A61M1/3633 , Y10T436/25375
摘要： A filter and method for removing selected materials from a biological fluid sample are provided. The filter comprises an outer housing, inlet, and outlet. A plurality of filter surfaces are provided within the outer housing, and at least one coating is applied to the filter surfaces. The at least one coating comprises at least two binding modules that are in turn selectively bound to one another. One binding module is selectively bound to the filter surfaces and another binding module is configured to bind selectively to the selected materials that are to be removed from the fluid sample. As the fluid sample is allowed to pass through the inlet, outer housing, and outlet, the selected materials are selectively bound to the filter surfaces via the coating, thus producing a filtered product at the outlet.
摘要翻译：提供了用于从生物流体样品中去除所选材料的过滤器和方法。过滤器包括外壳，入口和出口。多个过滤器表面设置在外壳体内，并且至少一个涂层被施加到过滤器表面。所述至少一个涂层包括至少两个结合模块，所述至少两个结合模块又选择性地结合到另一个上。一个装订模块选择性地结合到过滤器表面，另一个装订模块被配置成选择性地结合待从流体样品中移除的所选择的材料。当流体样品被允许通过入口，外部壳体和出口时，所选择的材料通过涂层选择性地结合到过滤表面，从而在出口处产生过滤产物。

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