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1. 发明授权

US08050483B2 Method for image registration processes and X-ray angiography system 有权
标题翻译：图像配准过程和X射线血管造影系统的方法
公开(公告)号：US08050483B2
公开(公告)日：2011-11-01
申请号：US12070484
申请日：2008-02-19
申请人： Jan Boese , Jörn Justiz , Andreas Meyer , Marcus Pfister
发明人： Jan Boese , Jörn Justiz , Andreas Meyer , Marcus Pfister
IPC分类号： G06K9/00
CPC分类号： G06T7/38 , A61B2090/364 , G06T2207/10072 , G06T2207/10081 , G06T2207/10088 , G06T2207/30004 , G06T2207/30012 , G06T2207/30048
摘要： Registration of preoperatively acquired MRI images of soft parts to intraoperatively acquired X-ray images of soft parts is not possible. The invention shows a way of nevertheless using such preoperatively acquired images for superimposition with 2D projections of the soft parts, taking an indirect route via 3D/3D registration of images of the spinal column. For this purpose, 3D image data sets of the spinal column must be obtained separately on the one hand using MRI and on the other using the X-ray imaging system so that the 3D/3D registration produces a mapping rule which then also applies to the preoperatively acquired images of the soft part if the soft part images and the spinal images are acquired without intervening change in the patient position in the MRI scanner.
摘要翻译：将软件部分术前获取的MRI图像注册到软组件的术中获得的X射线图像是不可能的。本发明示出了一种使用这种预先获取的图像与软部件的2D投影叠加的方式，通过经脊柱的图像的3D / 3D对准进行间接路线。为此，必须使用MRI单独获得脊柱的3D图像数据集，另一方面必须使用X射线成像系统获得脊柱的3D图像数据集，使得3D / 3D注册产生映射规则，其然后也适用于如果获取软部分图像和脊柱图像而不在MRI扫描仪中的患者位置的中间改变，则在术前获取软部分的图像。

2. 发明申请

US20080212858A1 Method for image registration processes and X-ray angiography system 有权
标题翻译：图像配准过程和X射线血管造影系统的方法
公开(公告)号：US20080212858A1
公开(公告)日：2008-09-04
申请号：US12070484
申请日：2008-02-19
申请人： Jan Boese , Jorn Justiz , Andreas Meyer , Marcus Pfister
发明人： Jan Boese , Jorn Justiz , Andreas Meyer , Marcus Pfister
IPC分类号： G06K9/00
CPC分类号： G06T7/38 , A61B2090/364 , G06T2207/10072 , G06T2207/10081 , G06T2207/10088 , G06T2207/30004 , G06T2207/30012 , G06T2207/30048
摘要： Registration of preoperatively acquired MRI images of soft parts to intraoperatively acquired X-ray images of soft parts is not possible. The invention shows a way of nevertheless using such preoperatively acquired images for superimposition with 2D projections of the soft parts, taking an indirect route via 3D/3D registration of images of the spinal column. For this purpose, 3D image data sets of the spinal column must be obtained separately on the one hand using MRI and on the other using the X-ray imaging system so that the 3D/3D registration produces a mapping rule which then also applies to the preoperatively acquired images of the soft part if the soft part images and the spinal images are acquired without intervening change in the patient position in the MRI scanner.
摘要翻译：将软件部分术前获取的MRI图像注册到软组件的术中获得的X射线图像是不可能的。本发明示出了一种使用这种预先获取的图像与软部件的2D投影叠加的方式，通过经脊柱的图像的3D / 3D对准进行间接路线。为此，必须使用MRI单独获得脊柱的3D图像数据集，另一方面必须使用X射线成像系统获得脊柱的3D图像数据集，使得3D / 3D注册产生映射规则，其然后也适用于如果获取软部分图像和脊柱图像而不在MRI扫描仪中的患者位置的中间改变，则在术前获取软部分的图像。

3. 发明申请

US20070167706A1 Method and apparatus for visually supporting an electrophysiological catheter application in the heart by means of bidirectional information transfer 审中-公开
标题翻译：通过双向信息传递在心脏中视觉上支持电生理导管应用的方法和装置
公开(公告)号：US20070167706A1
公开(公告)日：2007-07-19
申请号：US11516138
申请日：2006-09-06
申请人： Jan Boese , Andreas Meyer , Marcus Pfister , Norbert Rahn
发明人： Jan Boese , Andreas Meyer , Marcus Pfister , Norbert Rahn
IPC分类号： A61B5/05
CPC分类号： G06T11/008 , A61B18/1492 , A61B90/36 , A61B2017/00053 , A61B2018/00839 , A61B2090/364
摘要： Method and apparatus for visually supporting an electrophysiological catheter application in the heart by means of bidirectional information transfer The present invention relates to a method and apparatus for visually supporting an electrophysiological catheter application in the heart. For the method, 3D image data of at least the heart, which is captured using a tomographic 3D imaging method prior to execution of the catheter application, and electroanatomical 3D mapping data of at least one area of the heart to be treated, which is captured during execution of the catheter application, is provided and the electroanatomical 3D mapping data and/or at least part of the 3D image data is displayed during execution of the catheter application. The method is characterized in that, in the electroanatomical 3D mapping data and/or the 3D image data, the contour of one or more areas (3) relevant to the catheter application is captured and transferred to the other system in each case on which the areas (3) are superimposed as a single polyline (5) in the representation (2, 4) of the electroanatomical 3D mapping data and/or 3D image data. The method proposed and the associated apparatus provide the user with a rapid overview of the areas relevant to the catheter application.
摘要翻译：通过双向信息转移在心脏中视觉上支持电生理学导管应用的方法和装置技术领域本发明涉及用于在心脏中视觉上支持电生理导管应用的方法和装置。对于该方法，在执行导管应用之前使用断层摄影3D成像方法捕获的至少心脏的3D图像数据以及被捕获的心脏的至少一个区域的电解剖3D绘图数据在执行导管应用期间，并且在执行导管应用期间显示电解剖3D绘图数据和/或3D图像数据的至少一部分。该方法的特征在于，在电解剖3D图数据和/或3D图像数据中，与导管应用相关的一个或多个区域（3）的轮廓被捕获并传送到另一个系统，在每个情况下，在电解剖3D绘图数据和/或3D图像数据的表示（2,4）中，区域（3）被叠加为单个折线（5）。提出的方法和相关联的装置向用户提供与导管应用相关的区域的快速概述。

4. 发明申请

US20060285738A1 Method and device for marking three-dimensional structures on two-dimensional projection images 有权
标题翻译：用于在二维投影图像上标记三维结构的方法和装置
公开(公告)号：US20060285738A1
公开(公告)日：2006-12-21
申请号：US11453623
申请日：2006-06-15
申请人： Jan Boese , Andreas Meyer , Marcus Pfister , Norbert Rahn
发明人： Jan Boese , Andreas Meyer , Marcus Pfister , Norbert Rahn
IPC分类号： G06K9/00
CPC分类号： G03B42/026 , A61B6/02 , A61B6/4441 , A61B6/466 , A61B6/469 , A61B6/481 , A61B6/503 , A61B6/504 , A61B6/541 , A61B34/20 , A61B90/37 , A61B2017/00703 , A61B2090/364 , A61B2090/376 , G03B42/021
摘要： The invention relates to a method and a device for marking three-dimensional structures on two-dimensional projection images of an object, with which a position marker is determined on two projection images of the object recorded from different projection directions, from which the position of the position marker in the three-dimensional space is calculated so that further, subsequently recorded projection images can be displayed superimposed by the position marker.
摘要翻译：本发明涉及一种用于标记物体的二维投影图像上的三维结构的方法和装置，利用该方法和装置在从不同投影方向记录的物体的两个投影图像上确定位置标记，计算三维空间中的位置标记，使得随后记录的投影图像可以通过位置标记叠加显示。

5. 发明授权

US07760926B2 Method and device for marking three-dimensional structures on two-dimensional projection images 有权
标题翻译：用于在二维投影图像上标记三维结构的方法和装置
公开(公告)号：US07760926B2
公开(公告)日：2010-07-20
申请号：US11453623
申请日：2006-06-15
申请人： Jan Boese , Andreas Meyer , Marcus Pfister , Norbert Rahn
发明人： Jan Boese , Andreas Meyer , Marcus Pfister , Norbert Rahn
IPC分类号： G06K9/00
CPC分类号： G03B42/026 , A61B6/02 , A61B6/4441 , A61B6/466 , A61B6/469 , A61B6/481 , A61B6/503 , A61B6/504 , A61B6/541 , A61B34/20 , A61B90/37 , A61B2017/00703 , A61B2090/364 , A61B2090/376 , G03B42/021
摘要： The invention relates to a method and a device for marking three-dimensional structures on two-dimensional projection images of an object, with which a position marker is determined on two projection images of the object recorded from different projection directions, from which the position of the position marker in the three-dimensional space is calculated so that further, subsequently recorded projection images can be displayed superimposed by the position marker.
摘要翻译：本发明涉及一种用于标记物体的二维投影图像上的三维结构的方法和装置，利用该方法和装置在从不同投影方向记录的物体的两个投影图像上确定位置标记，计算三维空间中的位置标记，使得随后记录的投影图像可以通过位置标记叠加显示。

6. 发明申请

US20070083103A1 Arrangement for acquiring an object 审中-公开
标题翻译：获取物品的安排
公开(公告)号：US20070083103A1
公开(公告)日：2007-04-12
申请号：US11529681
申请日：2006-09-28
申请人： Jan Boese , Martin Kleen , Andreas Meyer , Marcus Pfister , Norbert Rahn
发明人： Jan Boese , Martin Kleen , Andreas Meyer , Marcus Pfister , Norbert Rahn
IPC分类号： A61B5/05
CPC分类号： G01B21/20 , A61B5/06 , A61B5/062 , A61B6/4441 , A61B6/467 , A61B6/5235
摘要： The invention relates to an arrangement having a 3D device, the 3D device being embodied for acquiring an objects and generating a 3D acquisition result representing the object at least partially in at least three dimensions. The arrangement also has a 2D device, the 2D device being embodied for acquiring the object and generating a 2D acquisition result representing the object in at least two dimensions. The 2D acquisition result represents the object at least partially, in particular a top view of the object, a view through the object or a section through the objects. The invention is characterized in that the 3D devices and the 2D devices are connected to one another, mechanically electrically, in such a way that a part of the 3D acquisition result corresponding to an object location can be assigned to a part of the 2D acquisition result corresponding to the same object location.
摘要翻译：本发明涉及一种具有3D装置的装置，该3D装置被实施为用于获取对象并且至少部分地至少三维地生成表示该对象的3D采集结果。该装置还具有2D设备，2D设备被实现为用于获取对象并在至少二维中生成表示对象的2D采集结果。 2D采集结果至少部分地表示对象，特别是对象的顶视图，通过对象的视图或通过对象的部分。本发明的特征在于，3D装置和2D装置彼此机械电连接，使得对应于对象位置的3D采集结果的一部分可被分配给2D采集结果的一部分对应于相同的对象位置。

7. 发明授权

US07778690B2 Method for locating a medical instrument during an intervention performed on the human body 有权
标题翻译：在对人体进行的干预中定位医疗器械的方法
公开(公告)号：US07778690B2
公开(公告)日：2010-08-17
申请号：US11805215
申请日：2007-05-22
申请人： Jan Boese , Marcus Pfister
发明人： Jan Boese , Marcus Pfister
IPC分类号： A61B5/05 , H01J35/00
CPC分类号： A61B5/063 , A61B5/06 , A61B5/062 , A61B6/12 , A61B34/20 , A61B90/36 , A61B2034/2051 , A61B2090/376 , G06F19/00
摘要： The invention relates to a method for locating a medical instrument during an intervention performed on the human body using an X-ray image recording system and an electromagnetic locating system whose systems of coordinates have been or will be mutually registered, with a first item of positional information about the instrument being obtained continuously by means of the locating system and in each case two two-dimensional X-ray images positioned at an angle to each other being intermittently recorded by means of the X-ray image recording system, from which images a second item of positional information about the instrument is determined and compared with the first item of positional information, after which the first item of positional information will be corrected depending on the comparison result taking account of the second item of positional information obtained from the X-ray images.
摘要翻译：本发明涉及一种用于在使用X射线图像记录系统对人体进行的干预期间定位医疗器械的方法以及其坐标系统已经或将要相互注册的电磁定位系统，其中第一项位置关于通过定位系统连续获得的仪器的信息，并且在每种情况下，通过X射线图像记录系统间歇地记录彼此成角度定位的两个二维X射线图像，图像a 确定与仪器相关的位置信息的第二项，并将其与位置信息的第一项进行比较，之后根据从X轴获得的位置信息的第二项目考虑的比较结果来修正位置信息的第一项，射线图像。

8. 发明申请

US20060235295A1 Method for movement-compensation in imaging 有权
公开(公告)号：US20060235295A1
公开(公告)日：2006-10-19
申请号：US11402320
申请日：2006-04-11
申请人： Jan Boese , Martin Kleen , Marcus Pfister , Norbert Rahn
发明人： Jan Boese , Martin Kleen , Marcus Pfister , Norbert Rahn
IPC分类号： A61B5/05
CPC分类号： A61B8/5276 , A61B5/7285 , A61B6/5264 , A61B6/527 , A61B6/541 , A61B8/543 , G06T7/20
摘要： In a method for mathematical compensation of a periodic movement of an organ in a first image-generation method used to image said organ, two time series of three-dimensional image data are acquired using gating, one by the first image-generation method and one by the second image-generation method, the image data that have been acquired by the second image-generation method being used to calculate motion fields which are applied for the compensation of the data from the time series which was acquired by the first image-generation method. The compensation encompasses the mathematical inclusion of motion fields and the mapping of the image data to a reference time. All the image data mapped back to the reference time are added together.

9. 发明申请

US20050197559A1 Method for endoluminal imaging with movement correction 有权
标题翻译：用于运动矫正的腔内成像方法
公开(公告)号：US20050197559A1
公开(公告)日：2005-09-08
申请号：US11076537
申请日：2005-03-08
申请人： Jan Boese , Martin Kleen , Marcus Pfister , Norbert Rahn
发明人： Jan Boese , Martin Kleen , Marcus Pfister , Norbert Rahn
IPC分类号： G01N21/64 , A61B5/00 , A61B5/05 , A61B5/055 , A61B5/06 , A61B6/00 , A61B6/02 , A61B6/03 , A61B6/12 , A61B8/12 , A61B19/00 , A61M25/095 , G01N21/17
CPC分类号： A61B5/06 , A61B5/0073 , A61B5/0084 , A61B5/7207 , A61B5/7289 , A61B8/12 , A61B8/5238
摘要： The present invention relates to a method for imaging using an image-generating, endoluminal instrument (1) by means of which a sequence of 2D image data of a hollow channel (2), in particular a vessel, of an object under investigation is recorded, wherein the images are recorded in a known temporal relation to a periodic movement of the object under investigation and spatial coordinates of the image are captured by means of a position sensor during each recording of an image (5) and stored as position data (9, 10) together with the 2D image data of the image (5). The method is characterized in that first position data (10) which does not lie in a predefinable movement phase of the object under investigation is corrected, before or after being stored, by interpolation between second position data (9) which does lie in the specified movement phase and/or by subtraction or addition of predetermined values. By means of the method a movement correction of the data can be performed without the need to reduce the volume of recorded image material.
摘要翻译：本发明涉及一种使用图像生成的腔内器械（1）进行成像的方法，通过该方法，记录被调查对象的空心通道（2），特别是血管的2D图像数据的序列，其中图像以已知的时间关系记录在被调查对象的周期性运动中，并且在每次记录图像（5）期间通过位置传感器捕获图像的空间坐标，并将其存储为位置数据（9），10）与图像（5）的2D图像数据一起。该方法的特征在于，通过在位于指定的位置的第二位置数据（9）之间的内插来校正不在被调查对象的预定义移动阶段的第一位置数据（10），在存储之前或之后，移动阶段和/或通过减去或添加预定值。通过该方法，可以执行数据的移动校正，而不需要减少记录的图像材料的体积。

10. 发明申请

US20050187538A1 Remote control device for a medical probe 有权
标题翻译：用于医疗探头的遥控装置
公开(公告)号：US20050187538A1
公开(公告)日：2005-08-25
申请号：US10966754
申请日：2004-10-15
申请人： Jan Boese , Martin Kleen , Marcus Pfister , Norbert Rahn
发明人： Jan Boese , Martin Kleen , Marcus Pfister , Norbert Rahn
IPC分类号： G02B23/24 , A61B1/00 , A61B8/12 , A61B17/00 , A61B19/00 , A61M25/01 , A61M31/00 , G05D1/00
CPC分类号： A61B1/00039 , A61B34/70 , A61B34/74 , A61B34/76 , A61B34/77 , A61M25/0136
摘要： The device according to the invention ensures accurate and in particular sensitive navigation of the probe, which can be inserted into a body, despite the fact that the remote control uses simple means, by means of a movement (MR;MB;MP) corresponding intuitively to the navigation of a probe using the control device (1). Intuitive operation can be converted in particular using an inventive U-shaped embodiment of the control device (1). Sensitive controllability can be increased by transmitting the mechanical interaction between the probe and an environment under examination to the control device (1) and thus directly to the operating hand (3) by means of inventive feedback.
摘要翻译：根据本发明的装置，尽管远程控制使用简单的手段，借助于直观对应的移动（MR; MB; MP），可以确保探头的精确和特别灵敏的导航，其可插入到身体中使用控制装置（1）到探针的导航。可以使用控制装置（1）的本发明的U形实施例特别地转换直观的操作。可以通过发明反馈将探测器和被检查环境之间的机械相互作用传输到控制装置（1），从而直接传递给操作手（3）来增加敏感的可控性。

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