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1. 发明申请

US20100280363A1 Electromagnetic Navigation of Medical Instruments for Cardiothoracic Surgery 审中-公开
标题翻译：医学仪器用于心胸外科的电磁导航
公开(公告)号：US20100280363A1
公开(公告)日：2010-11-04
申请号：US12767163
申请日：2010-04-26
申请人： James Skarda , Mark Stewart , James Keogh , David Francischelli , Kenneth C. Gardeski , Thomas A. Poss , Michael Neidert
发明人： James Skarda , Mark Stewart , James Keogh , David Francischelli , Kenneth C. Gardeski , Thomas A. Poss , Michael Neidert
IPC分类号： A61B5/05
CPC分类号： A61B1/00154 , A61B1/00135 , A61B34/20 , A61B90/361 , A61B2017/00243 , A61B2017/00336 , A61B2034/2051 , A61N1/056
摘要： The present invention provides devices, instruments, systems, and methods to navigate medical instruments within the thoracic cavity. More specifically, the present invention provides a navigation system comprising medical instruments having electromagnetic tracking functionality and the integration of previously acquired imaging into a user interface of the navigation system.
摘要翻译：本发明提供了用于在胸腔内导航医疗器械的装置，仪器，系统和方法。更具体地，本发明提供了一种导航系统，其包括具有电磁跟踪功能的医疗仪器和将先前获取的成像集成到导航系统的用户界面中。

2. 发明授权

US09579161B2 Method and apparatus for tracking a patient 有权
标题翻译：用于跟踪患者的方法和装置
公开(公告)号：US09579161B2
公开(公告)日：2017-02-28
申请号：US12115907
申请日：2008-05-06
申请人： Steven L. Hartmann , Laurent Verard , James Kelley , Kenneth Gardeski , Kevin Thomas Wu , Michael Neidert
发明人： Steven L. Hartmann , Laurent Verard , James Kelley , Kenneth Gardeski , Kevin Thomas Wu , Michael Neidert
IPC分类号： A61B34/20
CPC分类号： A61B34/20 , A61B2034/2051 , A61B2090/364
摘要： A system for tracking a patient is provided. The system can include a first reference frame coupled to a first portion of an anatomical structure. The system can include a second reference frame, which can be coupled to a second portion of the anatomical structure. The system can also include a first tracking device coupled to the first reference frame and a second tracking device coupled to the second reference frame. The system can also include a tracking system that can track a position of the first tracking device and the second tracking device to ensure that the position of the first reference frame relative to the anatomical structure is substantially the same throughout a surgical procedure.
摘要翻译：提供了一种跟踪患者的系统。该系统可以包括耦合到解剖结构的第一部分的第一参考框架。该系统可以包括第二参考框架，其可耦合到解剖结构的第二部分。该系统还可以包括耦合到第一参考帧的第一跟踪设备和耦合到第二参考帧的第二跟踪设备。该系统还可以包括跟踪系统，其可以跟踪第一跟踪设备和第二跟踪设备的位置，以确保第一参考框架相对于解剖结构的位置在整个外科手术过程中基本相同。

3. 发明申请

US20060224118A1 Medical fluid delivery system 审中-公开
标题翻译：医疗液体输送系统
公开(公告)号：US20060224118A1
公开(公告)日：2006-10-05
申请号：US11097071
申请日：2005-03-31
申请人： Mary Morris , Michael Neidert , Kenneth Gardeski
发明人： Mary Morris , Michael Neidert , Kenneth Gardeski
IPC分类号： A61M5/178
CPC分类号： A61M5/158 , A61M25/0084
摘要： A medical fluid delivery system is provided including a steerable, guide catheter, a delivery catheter adapted for deployment at a targeted tissue site using the steerable guide catheter, the delivery catheter including a proximal port, a distal port, and a lumen extending between the proximal and distal ports; a distal fixation element coupled to the delivery catheter so as to position the distal port adjacent the targeted tissue site; and a flexible hollow needle adapted to be advanced through the delivery catheter lumen, the flexible needle including a tissue-piercing distal tip for extending from the distal port of the delivery catheter for advancement into the targeted tissue site and a proximal end for extending from the proximal port of the delivery catheter through which a medical fluid is delivered.
摘要翻译：提供了一种医疗流体输送系统，其包括可转向的导向导管，适于使用可转向引导导管在目标组织部位展开的输送导管，所述输送导管包括近端口，远端口和在近端和远端口; 远端固定元件，其联接到所述输送导管，以便将所述远端口邻近所述目标组织部位定位; 以及柔性中空针，其适于前进穿过输送导管腔，所述柔性针包括组织穿刺远侧末端，用于从输送导管的远端延伸进入目标组织部位，以及近端从输送导管的近端口，通过该端口传送医用流体。

4. 发明申请

US20090270714A1 Device to Treat Chronic Total Occlusions Using Energy Imparted By External Imaging 审中-公开
标题翻译：使用外部成像引发的能量治疗慢性完全闭塞的装置
公开(公告)号：US20090270714A1
公开(公告)日：2009-10-29
申请号：US12108921
申请日：2008-04-24
申请人： Niall Duffy , Michael Neidert
发明人： Niall Duffy , Michael Neidert
IPC分类号： A61B5/05 , A61B8/12
CPC分类号： A61B5/055 , A61B5/02007 , A61B17/2202 , A61B18/08 , A61B34/20 , A61B2034/2051 , A61B2090/374 , A61B2090/378 , A61N1/403
摘要： A visualization and treatment system for treating a chronic total occlusion. The system includes an elongated member configured to be tracked to the chronic total occlusion. The elongated member has a transducer located at a distal end of the elongated member. The transducer is constructed and arranged to convert a first form of energy into a second form of energy to treat the chronic total occlusion. The system also includes an external imaging system constructed and arranged to create an image of the chronic total occlusion and to provide the first form of energy to the transducer.
摘要翻译：一种用于治疗慢性完全闭塞的可视化和治疗系统。该系统包括细长构件，构造成跟踪到慢性完全闭塞。细长构件具有位于细长构件的远端处的换能器。换能器被构造和布置成将第一形式的能量转换成第二形式的能量以治疗慢性全闭塞。该系统还包括外部成像系统，该外部成像系统构造和布置成产生慢性完全闭塞的图像并向换能器提供第一形式的能量。

5. 发明申请

US20090281417A1 Method and apparatus for tracking a patient 有权
标题翻译：用于跟踪患者的方法和装置
公开(公告)号：US20090281417A1
公开(公告)日：2009-11-12
申请号：US12115907
申请日：2008-05-06
申请人： Steven L. Hartmann , Laurent Verard , James Kelley , Kenneth Gardeski , Kevin Thomas Wu , Michael Neidert
发明人： Steven L. Hartmann , Laurent Verard , James Kelley , Kenneth Gardeski , Kevin Thomas Wu , Michael Neidert
IPC分类号： A61B17/00
CPC分类号： A61B34/20 , A61B2034/2051 , A61B2090/364
摘要： A system for tracking a patient is provided. The system can include a first reference frame coupled to a first portion of an anatomical structure. The system can include a second reference frame, which can be coupled to a second portion of the anatomical structure. The system can also include a first tracking device coupled to the first reference frame and a second tracking device coupled to the second reference frame. The system can also include a tracking system that can track a position of the first tracking device and the second tracking device to ensure that the position of the first reference frame relative to the anatomical structure is substantially the same throughout a surgical procedure.
摘要翻译：提供了一种跟踪患者的系统。该系统可以包括耦合到解剖结构的第一部分的第一参考框架。该系统可以包括第二参考框架，其可耦合到解剖结构的第二部分。该系统还可以包括耦合到第一参考帧的第一跟踪设备和耦合到第二参考帧的第二跟踪设备。该系统还可以包括跟踪系统，其可以跟踪第一跟踪设备和第二跟踪设备的位置，以确保第一参考框架相对于解剖结构的位置在整个外科手术过程中基本相同。

6. 发明申请

US20090259284A1 Resonating Stent or Stent Element 审中-公开
标题翻译：共振支架或支架元件
公开(公告)号：US20090259284A1
公开(公告)日：2009-10-15
申请号：US12100574
申请日：2008-04-10
申请人： Dwayne S. Yamasaki , Michael Neidert
发明人： Dwayne S. Yamasaki , Michael Neidert
IPC分类号： A61F2/82 , A61F2/84 , A61N1/00 , A61B5/06
CPC分类号： A61B5/06 , A61B90/39 , A61B2034/2051 , A61B2090/397 , A61F2/07 , A61F2/86 , A61F2220/0075 , A61F2230/0054 , A61L31/022 , A61L31/18 , A61N1/40 , A61N2/02
摘要： A tubular member adapted for endovascular delivery in a human patient comprises a tubular wire framework and the tubular wire framework forms the core of a signal device. The signal device further includes a coil, which is wrapped around the core to form an inductor, and a capacitor coupled to the inductor to form an inductor capacitor circuit. The signal device can be excited and signals acquired therefrom to determine the position and/or orientation of the signal device and the tubular member. The relative positions and/or orientations of (1) the signal device and/or the tubular member and (2) a device having a signal generating element or a signal generating element being advanced toward the signal device, tubular member or framework can be monitored. Relative positions and/or orientations of a plurality of signal devices in a tubular wire framework also can be determined after the framework is deployed in a vessel and compared to predetermined positions and/or orientations.
摘要翻译：适于在人类患者中进行血管内递送的管状构件包括管状线框架，并且管状线框架形成信号装置的核心。该信号装置还包括线圈，该线圈缠绕在芯上以形成电感器，以及耦合到电感器的电容器以形成电感器电容器电路。可以激励信号装置并从中获取信号以确定信号装置和管状构件的位置和/或取向。（1）信号装置和/或管状构件的相对位置和/或取向和（2）可以监测具有朝向信号装置，管状构件或框架前进的信号产生元件或信号产生元件的装置。管状线框架中的多个信号装置的相对位置和/或取向也可以在将框架部署在容器中并与预定位置和/或取向进行比较之后确定。

7. 发明申请

US20070164900A1 Therapy delivery system including a navigation element 有权
标题翻译：治疗传递系统包括导航元件
公开(公告)号：US20070164900A1
公开(公告)日：2007-07-19
申请号：US11322393
申请日：2005-12-30
申请人： Mark Schneider , Michael Neidert , Kenneth Gardeski , Johnson Goode
发明人： Mark Schneider , Michael Neidert , Kenneth Gardeski , Johnson Goode
IPC分类号： G01S1/00
CPC分类号： A61B19/5244 , A61B5/0084 , A61B5/055 , A61B5/6852 , A61B10/04 , A61B17/1214 , A61B17/3478 , A61B18/1492 , A61B18/18 , A61B34/20 , A61B34/25 , A61B90/36 , A61B90/39 , A61B2018/00071 , A61B2018/00839 , A61B2034/2051 , A61B2090/3958
摘要： An electromagnetic receiver assembly is included in a navigation element for a therapy delivery system. If the system is modular, the navigation element may be an insertable module thereof and/or include a lumen to receive another insertable module.
摘要翻译：用于治疗传送系统的导航元件中包括电磁接收器组件。如果系统是模块化的，则导航元件可以是其可插入模块和/或包括用于接收另一可插入模块的内腔。

8. 发明申请

US20050277889A1 Modular medical injection system 有权
标题翻译：模块化注射系统
公开(公告)号：US20050277889A1
公开(公告)日：2005-12-15
申请号：US10867059
申请日：2004-06-14
申请人： Michael Neidert , Kenneth Gardeski , David Quinn , Russell Redmond , Michael Collinson , Claude Vidal
发明人： Michael Neidert , Kenneth Gardeski , David Quinn , Russell Redmond , Michael Collinson , Claude Vidal
IPC分类号： A61M5/00 , A61M25/00 , A61M25/06
CPC分类号： A61M25/0068 , A61M25/0097 , A61M25/0102 , A61M25/0606 , A61M25/0662 , A61M2025/0004 , A61M2025/0073
摘要： A medical injection system includes an elongate injection apparatus and an actuator apparatus. The actuator apparatus includes a fitting for coupling the actuator apparatus to a delivery catheter and a reversible gripping means to grip the injection apparatus; the gripping means is included in a plunger that is slideably engaged with the fitting and directs the injection apparatus through a fitting lumen and through a catheter lumen, when the fitting is coupled to the catheter.
摘要翻译：医疗注射系统包括细长注射装置和致动器装置。致动器装置包括用于将致动器装置连接到输送导管的配件和用于夹紧注射装置的可逆夹持装置; 夹紧装置被包括在与配件可滑动地接合的柱塞中，并且当配件联接到导管时，引导注射装置通过配合内腔并通过导管腔。

9. 发明授权

US06666886B1 Tissue equivalent approach to a tissue-engineered cardiovascular valve 有权
标题翻译：组织工程心血管瓣膜的组织等效方法
公开(公告)号：US06666886B1
公开(公告)日：2003-12-23
申请号：US09505121
申请日：2000-02-16
申请人： Robert T. Tranquillo , Timothy S. Girton , Michael Neidert
发明人： Robert T. Tranquillo , Timothy S. Girton , Michael Neidert
IPC分类号： A61F206
CPC分类号： A61L27/3804 , A61F2/2415 , A61F2/2475 , A61L27/225 , A61L27/24 , A61L27/3843
摘要： The invention provides a molded valve leaflet containing a molded biopolymer having fibrils and cells within the molded biopolymer, wherein the fibrils of the molded biopolymer have commisure-to-commisure alignment. The invention also provides a valve equivalent containing a plurality of molded valve leaflets that are connected to a base, wherein the molded valve leaflets include a molded biopolymer having fibrils and cells within the molded biopolymer, wherein the fibrils of the molded biopolymer have commisure-to-commisure alignment.
摘要翻译：本发明提供了一种模制的瓣膜小叶，其包含在模制的生物聚合物内具有原纤维和细胞的模制生物聚合物，其中模制的生物聚合物的原纤维具有一致的连续对齐。本发明还提供了一种阀门等效物，其包含连接到基座的多个模制的瓣叶，其中模制的瓣叶包括在模制的生物聚合物中具有原纤维和细胞的模制生物聚合物，其中模制的生物聚合物的原纤维具有 - 对齐。

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