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1. 发明授权

US4806467A Method for the detection of equine infectious anemia and other retrovirus infections using a competitive enzyme-linked immunoabsorbent assay and reagents useful in the same 失效
标题翻译：使用竞争性酶联免疫吸附测定法检测马传染性贫血和其他逆转录病毒感染的方法和相同的试剂
公开(公告)号：US4806467A
公开(公告)日：1989-02-21
申请号：US789910
申请日：1985-10-21
申请人： James P. Porter , Tatsuo Matsushita , Lyndal K. Hesterberg
发明人： James P. Porter , Tatsuo Matsushita , Lyndal K. Hesterberg
IPC分类号： G01N33/543 , G01N33/569 , G01N33/53
CPC分类号： G01N33/56988 , G01N33/543
摘要： The present invention relates to a method of detecting either antibody or antigen in the serum of horses infected with equine infectious anemia using a competitive enzyme-linked immunoabsorbent assay technique and reagents useful in such an assay. The competitive enzyme-linked immunoabsorbent assay incorporates a purified virus antigen conjugate and a monoclonal antibody specific for the virus antigen as both the reacting and competing components. Alternatively, the competitive enzyme-linked immunoabsorbent assay incorporates a purified virus antigen and a monoclonal antibody conjugate specific for the viral antigen as both reacting and competing components. This invention also relates to detecting antigen and antibody found in other retrovirus infections such as Acquired Immunodeficiency Syndrome in humans.
摘要翻译：本发明涉及使用竞争性酶联免疫吸附测定技术和用于该测定中的试剂检测用马感染性贫血感染的马的血清中的抗体或抗原的方法。竞争性酶联免疫吸附测定法将纯化的病毒抗原结合物和针对病毒抗原特异性的单克隆抗体作为反应和竞争组分。或者，竞争性酶联免疫吸附测定法将纯化的病毒抗原和针对病毒抗原特异性的单克隆抗体结合作为反应和竞争组分。本发明还涉及检测其它逆转录病毒感染如人类获得性免疫缺陷综合征中发现的抗原和抗体。

2. 发明授权

US5945294A Method to detect IgE 失效
标题翻译：检测IgE的方法
公开(公告)号：US5945294A
公开(公告)日：1999-08-31
申请号：US756387
申请日：1996-11-26
申请人： Glenn R. Frank , James P. Porter , Keith E. Rushlow , Donald L. Wassom
发明人： Glenn R. Frank , James P. Porter , Keith E. Rushlow , Donald L. Wassom
IPC分类号： G01N33/566 , C07K14/735 , C12N5/10 , C12N15/09 , G01N33/53 , G01N33/68 , C12Q1/68 , G01N33/554 , G01N33/567
CPC分类号： G01N33/6854 , G01N2333/70535 , G01N2800/24
摘要： The present invention includes a method to detect IgE using a human Fc epsilon receptor (Fc.sub..epsilon. R) to detect IgE antibodies in a biological sample from a cat, a dog, or a horse. The present invention also relates to kits to perform such methods.
摘要翻译：本发明包括使用人Fcε受体（FcεR）检测来自猫，狗或马的生物样品中的IgE抗体的IgE的方法。本发明还涉及用于执行这些方法的试剂盒。

3. 发明授权

US06682894B2 Method to detect IgE 有权
标题翻译：检测IgE的方法
公开(公告)号：US06682894B2
公开(公告)日：2004-01-27
申请号：US09944277
申请日：2001-08-30
申请人： Glenn R. Frank , James P. Porter , Keith E. Rushlow , Donald L. Wassom
发明人： Glenn R. Frank , James P. Porter , Keith E. Rushlow , Donald L. Wassom
IPC分类号： C12Q168
CPC分类号： G01N33/6854 , G01N2333/70535 , G01N2800/24
摘要： The present invention includes a method to detect IgE using a human Fc epsilon receptor (Fc&egr;R) to detect IgE antibodies in a biological sample from a cat, a dog, or a horse. The present invention also relates to kits to perform such methods.
摘要翻译：本发明包括使用人Fcε受体（FcepsilonR）检测来自猫，狗或马的生物样品中的IgE抗体的IgE的方法。本发明还涉及用于执行这些方法的试剂盒。

4. 发明授权

US06309832B1 Method to detect IgE 有权
标题翻译：检测IgE的方法
公开(公告)号：US06309832B1
公开(公告)日：2001-10-30
申请号：US09285873
申请日：1999-03-31
申请人： Glenn R. Frank , James P. Porter , Keith E. Rushlow , Donald L. Wassom
发明人： Glenn R. Frank , James P. Porter , Keith E. Rushlow , Donald L. Wassom
IPC分类号： C12Q158
CPC分类号： G01N33/6854 , G01N2333/70535 , G01N2800/24
摘要： The present invention includes a method to detect IgE using a human Fc epsilon receptor (Fc&egr;R) to detect IgE antibodies in a biological sample from a cat, a dog, or a horse. The present invention also relates to kits to perform such methods.
摘要翻译：本发明包括使用人Fcε受体（FcepsiR）检测来自猫，狗或马的生物样品中的IgE抗体的IgE的方法。本发明还涉及用于执行这些方法的试剂盒。

5. 发明授权

US5958880A Feline Fc epsilon receptor alpha chain proteins and therapeutic uses thereof 失效
标题翻译： FelineFcεε受体α链蛋白及其治疗用途
公开(公告)号：US5958880A
公开(公告)日：1999-09-28
申请号：US768964
申请日：1996-12-19
申请人： Glenn R. Frank , James P. Porter , Keith E. Rushlow , Donald L. Wassom , Eric R. Weber
发明人： Glenn R. Frank , James P. Porter , Keith E. Rushlow , Donald L. Wassom , Eric R. Weber
IPC分类号： G01N33/53 , A61K38/00 , A61K39/395 , A61K45/00 , A61K48/00 , A61P17/00 , A61P37/08 , C07K14/705 , C07K14/735 , C07K16/18 , C07K16/28 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N7/00 , C12N15/09 , C12N15/12 , C12Q1/68 , G01N33/566 , G01N33/68 , C07K14/435 , A61K38/17 , A61K39/35
CPC分类号： G01N33/6857 , C07K14/70535 , A61K38/00 , C12N2799/026
摘要： The present invention relates to feline Fc epsilon receptor alpha chain nucleic acid molecules, proteins encoded by such nucleic acid molecules, antibodies raised against such proteins, and inhibitors of such proteins. The present invention also includes methods to detect IgE using such proteins and antibodies. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to mediate Fc epsilon receptor-mediated biological responses.
摘要翻译：本发明涉及猫科动物Fcε受体α链核酸分子，由这种核酸分子编码的蛋白质，针对这种蛋白质产生的抗体，以及这种蛋白质的抑制剂。本发明还包括使用这种蛋白质和抗体检测IgE的方法。本发明还包括包含这些蛋白质，核酸分子，抗体和/或抑制化合物的治疗组合物，以及这些治疗组合物用于介导Fcε受体介导的生物反应的治疗组合物。

6. 发明申请

US20150094905A1 VEHICLE INSPECTION VERIFICATION AND DIAGNOSTIC UNIT 有权
标题翻译：车辆检验验证和诊断单元
公开(公告)号：US20150094905A1
公开(公告)日：2015-04-02
申请号：US14041220
申请日：2013-09-30
申请人： Timothy J. Frashure , Richard J. Conklin , James P. Porter
发明人： Timothy J. Frashure , Richard J. Conklin , James P. Porter
IPC分类号： G07C5/06 , G01M17/007
CPC分类号： G07C5/06 , B60T17/22 , G01M17/007
摘要： A diagnostic display device is coupled to a vehicle data bus and receives vehicle identification information which is used to identify one or more expected onboard systems installed on the vehicle. Expected systems are queried to determine that they are present and operating properly. Presence and operation status information are stored and/or presented to a user to facilitate automated vehicle system inspection.
摘要翻译：诊断显示装置耦合到车辆数据总线并且接收用于识别安装在车辆上的一个或多个期望的车载系统的车辆识别信息。查询预期系统以确定它们是否存在并正常运行。将存在和操作状态信息存储和/或呈现给用户以便于自动车辆系统检查。

7. 发明授权

US07195767B2 Method to detect IgE 有权
标题翻译：检测IgE的方法
公开(公告)号：US07195767B2
公开(公告)日：2007-03-27
申请号：US11305447
申请日：2005-12-16
申请人： Glenn R. Frank , James P. Porter , Keith E. Rushlow , Donald L. Wassom
发明人： Glenn R. Frank , James P. Porter , Keith E. Rushlow , Donald L. Wassom
IPC分类号： A61K39/00 , A61K39/385 , A61K38/00 , C07K1/00 , C07K14/00 , C07K21/02 , C07K21/04
CPC分类号： G01N33/6854 , G01N2333/70535 , G01N2800/24
摘要： The present invention includes a method to detect IgE using a human Fc epsilon receptor (FcεR) to detect IgE antibodies in a biological sample from a cat, a dog, or a horse. The present invention also relates to kits to perform such methods.
摘要翻译：本发明包括使用人Fcε受体（FcεεR）R检测来自猫，狗或马的生物样品中的IgE抗体的IgE的方法。本发明还涉及用于执行这些方法的试剂盒。

8. 发明授权

US06391569B1 Method to detect Dirofilaria immitis infection 失效
标题翻译：检测疟原虫感染的方法
公开(公告)号：US06391569B1
公开(公告)日：2002-05-21
申请号：US08715628
申请日：1996-09-18
申请人： Robert B. Grieve , Glenn R. Frank , Roy R. Mondesire , James P. Porter , Nancy Wisnewski
发明人： Robert B. Grieve , Glenn R. Frank , Roy R. Mondesire , James P. Porter , Nancy Wisnewski
IPC分类号： G01N3353
CPC分类号： C07K14/4354 , G01N33/569 , G01N2333/4353
摘要： The present invention includes a method to detect D. immitis infection in a host animal using a D. immitis Di33 protein to detect anti-D. immitis Di33 antibodies in a bodily fluid of the animal. Also included is a method to detect D. immitis infection in a host animal using a D. immitis anti-Di33 protein to detect Di33 proteins in a bodily fluid of the animal. The present invention also relates to D. immitis detection kits that include either a Di33 protein or an anti-Di33 antibody; such kits also include a composition to detect an immunocomplex between the anti-Di33 antibody and D. immitis Di33 protein. The present invention also includes Di33 proteins, nucleic acid molecules encoding such proteins, as well as recombinant molecules and recombinant cells comprising such nucleic acid molecules, and anti-Di33 antibodies. Also included are methods to produce such proteins, nucleic acid molecules and antibodies.
摘要翻译：本发明包括使用D.Imitmiti Di33蛋白检测宿主动物中的D. immitis感染以检测抗-D的方法。 immitis Di33抗体在动物的体液中。还包括在宿主动物中使用D.emmitis抗-Di33蛋白检测动物体内的Di33蛋白的方法。本发明还涉及包含Di33蛋白或抗-Di33抗体的D.IMIITIS检测试剂盒; 这样的试剂盒还包括用于检测抗Di33抗体和D.Imitmiti Di33蛋白之间的免疫复合物的组合物。本发明还包括Di33蛋白，编码这种蛋白质的核酸分子，以及重组分子和包含这种核酸分子的重组细胞和抗Di33抗体。还包括产生这种蛋白质，核酸分子和抗体的方法。

9. 发明授权

US09563987B2 Vehicle inspection verification and diagnostic unit 有权
标题翻译：车辆检验验证单位
公开(公告)号：US09563987B2
公开(公告)日：2017-02-07
申请号：US14041220
申请日：2013-09-30
申请人： Timothy J. Frashure , Richard J. Conklin , James P. Porter
发明人： Timothy J. Frashure , Richard J. Conklin , James P. Porter
IPC分类号： G01M17/00 , G06F7/00 , G06F19/00 , G07C5/06 , G01M17/007 , B60T17/22
CPC分类号： G07C5/06 , B60T17/22 , G01M17/007
摘要： A diagnostic display device is coupled to a vehicle data bus and receives vehicle identification information which is used to identify one or more expected onboard systems installed on the vehicle. Expected systems are queried to determine that they are present and operating properly. Presence and operation status information are stored and/or presented to a user to facilitate automated vehicle system inspection.
摘要翻译：诊断显示装置耦合到车辆数据总线并且接收用于识别安装在车辆上的一个或多个期望的车载系统的车辆识别信息。查询预期系统以确定它们是否存在并正常运行。将存在和操作状态信息存储和/或呈现给用户以便于自动车辆系统检查。

10. 发明授权

US07870535B2 Distributed development environment for building internet applications by developers at remote locations 有权
标题翻译：分布式开发环境，用于在远程位置的开发人员构建互联网应用程序
公开(公告)号：US07870535B2
公开(公告)日：2011-01-11
申请号：US10468785
申请日：2002-02-21
申请人： Donald J. Rippert, Jr. , James P. Porter , Michael G. Condon
发明人： Donald J. Rippert, Jr. , James P. Porter , Michael G. Condon
IPC分类号： G06F9/44
CPC分类号： G06F8/20 , G06F11/36 , G06Q10/10
摘要： A system and a method for developing Internet-hosted business applications composed of web services and software for use in such environments where applications and application components interoperate to perform requested business functions. The system and method of the present invention utilize a software development application services provider module (DASP), an Instantiatior module, a Builder module, an Applications Service Provider (ASP) Infrastructure Platform (AIP) module, and a hosted production environment module. The system and method of the present invention seeks to maximize the use of prior work to eliminate repetition and reduce development cost and development time. With each new project the library and experience increases. The system and method of the present invention can use developers and testers situated in diverse locations so that a larger pool of skilled people can be employed, the work can be done around the clock by using people all over the globe, and the costs can be reduced by directing work to people in countries with lower labor rates. The system and method of the present invention increases efficiencies and reduces costs to all parties by partnering the developers with third parties who are brought in at the beginning of development.
摘要翻译：一种用于开发由Web服务和软件构成的因特网托管业务应用程序的系统和方法，用于在应用程序和应用程序组件互操作以执行请求的业务功能的环境中使用。本发明的系统和方法利用软件开发应用服务提供者模块（DASP），Instantiatior模块，Builder模块，应用服务提供商（ASP）基础设施平台（AIP）模块和托管生产环境模块）。本发明的系统和方法旨在最大限度地利用先前的工作来消除重复并降低开发成本和开发时间。随着每个新项目，图书馆和经验增加。本发明的系统和方法可以使用位于不同位置的开发人员和测试人员，以便能够雇佣更多的技术人才，通过使用世界各地的人们可以全天候完成工作，成本可以是通过向劳动力较低的国家的人们指导工作减少。本发明的系统和方法通过与开发人员在开发阶段带来的第三方合作来提高效率并降低成本。

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