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1. 发明申请

US20100013642A1 Systems And Methods For Evaluating A Physiological Condition 有权
标题翻译：用于评估生理条件的系统和方法
公开(公告)号：US20100013642A1
公开(公告)日：2010-01-21
申请号：US12497824
申请日：2009-07-06
申请人： James Nicholas Watson , Paul Stanley Addison , Edward M. McKenna , James P. Ochs
发明人： James Nicholas Watson , Paul Stanley Addison , Edward M. McKenna , James P. Ochs
IPC分类号： G08B23/00
CPC分类号： G06F19/00 , A61B5/14551 , A61B5/7207 , A61B5/726 , G06F19/3418 , G06K9/00516
摘要： A method and system are provided for evaluating in patient monitoring whether a signal is sensed optimally by receiving a signal, transforming the signal using a wavelet transform, generating a scalogram based at least in part on the transformed signal, identifying a pulse band in the scalogram, identifying a characteristic of the pulse band, determining, based on the characteristic of the pulse band, whether the signal is sensed optimally; and triggering an event. The characteristics of the pulse band and scalogram may be used to provide an indication of monitoring conditions.
摘要翻译：提供了一种方法和系统，用于评估在患者监视中是否通过接收信号来最佳地感测信号，使用小波变换变换信号，至少部分地基于经变换的信号产生缩放图，识别标尺中的脉冲带识别所述脉冲频带的特性，基于所述脉冲频带的特性确定所述信号是否被最佳地感测到; 并触发事件。可以使用脉冲带和标尺的特征来提供监测条件的指示。

2. 发明申请

US20110004069A1 Systems And Methods For Processing Physiological Signals In Wavelet Space 有权
标题翻译：小波空间处理生理信号的系统与方法
公开(公告)号：US20110004069A1
公开(公告)日：2011-01-06
申请号：US12497822
申请日：2009-07-06
申请人： James P. Ochs , Paul Stanley Addison , James Nicholas Watson
发明人： James P. Ochs , Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B5/00
CPC分类号： A61B5/7235 , A61B5/024 , A61B5/02416 , A61B5/14542 , A61B5/14551 , A61B5/7203 , A61B5/7207 , A61B5/7225 , A61B5/726 , A61B5/7264 , G06F19/00
摘要： Methods and systems are disclosed for analyzing multiple scale bands in the scalogram of a physiological signal in order to obtain information about a physiological process. An analysis may be performed to identify multiple scale bands that are likely to contain the information sought. Each scale band may be assessed to determine a band quality, and multiple bands may be combined based on the band quality. Information about a physiological process may determined based on the combined band. In an embodiment, analyzing multiple scale bands in a scalogram arising from a wavelet transformation of a photoplethysmograph signal may yield clinically relevant information about, among other things, the blood oxygen saturation of a patient.
摘要翻译：公开了用于分析生理信号的标尺中的多个尺度带以获得关于生理过程的信息的方法和系统。可以执行分析以识别可能包含所寻求信息的多个尺度带。可以评估每个标度带以确定带质量，并且可以基于带质量来组合多个频带。关于生理过程的信息可以基于组合的带来确定。在一个实施例中，分析由光体积描记信号的小波变换产生的标尺中的多个尺度带可产生关于患者的血氧饱和度的临床相关信息。

3. 发明授权

US08358213B2 Systems and methods for evaluating a physiological condition using a wavelet transform and identifying a band within a generated scalogram 有权
标题翻译：用于使用小波变换来评估生理状态并识别生成的标尺内的带的系统和方法
公开(公告)号：US08358213B2
公开(公告)日：2013-01-22
申请号：US12497824
申请日：2009-07-06
申请人： James Nicholas Watson , Paul Stanley Addison , Edward M. McKenna , James P. Ochs
发明人： James Nicholas Watson , Paul Stanley Addison , Edward M. McKenna , James P. Ochs
IPC分类号： G08B21/00
CPC分类号： G06F19/00 , A61B5/14551 , A61B5/7207 , A61B5/726 , G06F19/3418 , G06K9/00516
摘要： A method and system are provided for evaluating in patient monitoring whether a signal is sensed optimally by receiving a signal, transforming the signal using a wavelet transform, generating a scalogram based at least in part on the transformed signal, identifying a pulse band in the scalogram, identifying a characteristic of the pulse band, determining, based on the characteristic of the pulse band, whether the signal is sensed optimally; and triggering an event. The characteristics of the pulse band and scalogram may be used to provide an indication of monitoring conditions.
摘要翻译：提供了一种方法和系统，用于评估在患者监视中是否通过接收信号来最佳地感测信号，使用小波变换变换信号，至少部分地基于经变换的信号产生缩放图，识别标尺中的脉冲带识别所述脉冲频带的特性，基于所述脉冲频带的特性确定所述信号是否被最佳地感测到; 并触发事件。可以使用脉冲带和标尺的特征来提供监测条件的指示。

4. 发明授权

US08636667B2 Systems and methods for processing physiological signals in wavelet space 有权
标题翻译：用于处理小波空间中的生理信号的系统和方法
公开(公告)号：US08636667B2
公开(公告)日：2014-01-28
申请号：US12497822
申请日：2009-07-06
申请人： James P. Ochs , Paul Stanley Addison , James Nicholas Watson
发明人： James P. Ochs , Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B5/02 , A61B5/024 , A61B5/1455
CPC分类号： A61B5/7235 , A61B5/024 , A61B5/02416 , A61B5/14542 , A61B5/14551 , A61B5/7203 , A61B5/7207 , A61B5/7225 , A61B5/726 , A61B5/7264 , G06F19/00
摘要： Methods and systems are disclosed for analyzing multiple scale bands in the scalogram of a physiological signal in order to obtain information about a physiological process. An analysis may be performed to identify multiple scale bands that are likely to contain the information sought. Each scale band may be assessed to determine a band quality, and multiple bands may be combined based on the band quality. Information about a physiological process may determined based on the combined band. In an embodiment, analyzing multiple scale bands in a scalogram arising from a wavelet transformation of a photoplethysmograph signal may yield clinically relevant information about, among other things, the blood oxygen saturation of a patient.
摘要翻译：公开了用于分析生理信号的标尺中的多个尺度带以获得关于生理过程的信息的方法和系统。可以执行分析以识别可能包含所寻求信息的多个尺度带。可以评估每个标度带以确定带质量，并且可以基于带质量来组合多个频带。关于生理过程的信息可以基于组合的带来确定。在一个实施例中，分析由光体积描记信号的小波变换产生的标尺中的多个尺度带可以产生关于患者的血氧饱和度的临床相关信息。

5. 发明授权

US09357937B2 System and method for determining stroke volume of an individual 有权
标题翻译：用于确定个体的搏动量的系统和方法
公开(公告)号：US09357937B2
公开(公告)日：2016-06-07
申请号：US13605626
申请日：2012-09-06
申请人： James Nicholas Watson , Paul Stanley Addison
发明人： James Nicholas Watson , Paul Stanley Addison
IPC分类号： A61B5/0265 , A61B5/0285 , A61B5/029 , A61B5/0295
CPC分类号： A61B5/0265 , A61B5/0285 , A61B5/029 , A61B5/0295
摘要： A system for determining stroke volume of an individual. The system includes a skew-determining module that is configured to calculate a first derivative of photoplethysmogram (PPG) signals of the individual. The first derivative forms a derivative waveform. The skew-determining module is configured to determine a skew metric of the first derivative, wherein the skew metric is indicative of a morphology of at least one pulse wave detected from blood flow of the individual in the derivative waveform. The system also includes an analysis module that is configured to determine a stroke volume of the individual. The stroke volume is a function of the skew metric of the first derivative.
摘要翻译：一种用于确定个体的搏动量的系统。该系统包括偏差确定模块，其被配置为计算个体的光谱体积描记图（PPG）信号的一阶导数。一阶导数形成导数波形。偏移确定模块被配置为确定一阶导数的偏斜量度，其中偏斜度量指示从导数波形中个体的血流检测到的至少一个脉搏波的形态。该系统还包括分析模块，该分析模块被配置为确定个人的冲程体积。行程体积是一阶导数的偏差度量的函数。

6. 发明授权

US09066691B2 Using a continuous wavelet transform to generate a reference signal 有权
标题翻译：使用连续小波变换产生参考信号
公开(公告)号：US09066691B2
公开(公告)日：2015-06-30
申请号：US12245425
申请日：2008-10-03
申请人： Paul Stanley Addison , James Nicholas Watson
发明人： Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B5/1455 , A61B5/00 , G06K9/64
CPC分类号： A61B5/726 , A61B5/14551 , A61B5/7203
摘要： According to embodiments, systems and methods for generating reference signals are provided. A signal may be transformed using a continuous wavelet transform. Regions of interest may be selected from a transform or the resulting scalogram that may be used to generate a reference signal to use in filtering the signal or other signals. Cross-correlation techniques may be used to cancel noise components or isolate non-noise components from the signal. A physiological parameter may then be determined from the filtered signal or isolated components in the signal.
摘要翻译：根据实施例，提供了用于产生参考信号的系统和方法。可以使用连续小波变换来变换信号。感兴趣区域可以从可用于生成用于滤波信号或其他信号的参考信号的变换或生成的标尺中选择。可以使用互相关技术来消除噪声分量或从信号中隔离非噪声分量。然后可以从经滤波的信号或信号中的隔离分量确定生理参数。

7. 发明授权

US09060745B2 System and method for detecting fluid responsiveness of a patient 有权
标题翻译：用于检测患者的液体反应性的系统和方法
公开(公告)号：US09060745B2
公开(公告)日：2015-06-23
申请号：US13591455
申请日：2012-08-22
申请人： Mark Su , James Nicholas Watson , Paul Stanley Addison
发明人： Mark Su , James Nicholas Watson , Paul Stanley Addison
IPC分类号： A61B5/00 , A61B5/024 , A61B5/0245 , A61B5/026 , A61B5/1455 , A61B5/1495 , A61B6/00 , A61B8/06 , A61B5/0432 , A61B5/05
CPC分类号： A61B5/14552 , A61B5/0059 , A61B5/02007 , A61B5/0205 , A61B5/02416 , A61B5/0245 , A61B5/026 , A61B5/0261 , A61B5/0295 , A61B5/0432 , A61B5/0507 , A61B5/1495 , A61B5/4839 , A61B5/486 , A61B5/6826 , A61B5/7214 , A61B5/7225 , A61B5/7278 , A61B5/742 , A61B6/507 , A61B8/06
摘要： A system is configured to determine a fluid responsiveness index of a patient from a physiological signal. The system may include a sensor configured to be secured to an anatomical portion of the patient, and a monitor operatively connected to the sensor. The sensor is configured to sense a physiological characteristic of the patient. The monitor is configured to receive a physiological signal from the sensor. The monitor may include an index-determining module configured to determine the fluid responsiveness index through formation of a ratio of one or both of amplitude or frequency modulation of the physiological signal to baseline modulation of the physiological signal.
摘要翻译：系统被配置为从生理信号确定患者的流体反应性指数。系统可以包括被配置为固定到患者的解剖部分的传感器，以及可操作地连接到传感器的监视器。传感器被配置为感测患者的生理特征。监视器被配置成从传感器接收生理信号。监视器可以包括索引确定模块，其被配置为通过形成生理信号的幅度或频率调制与生理信号的基线调制之间的一个或两个的比率来确定流体响应性指数。

8. 发明授权

US08696585B2 Detecting a probe-off event in a measurement system 有权
标题翻译：检测测量系统中的探测事件
公开(公告)号：US08696585B2
公开(公告)日：2014-04-15
申请号：US12242894
申请日：2008-09-30
申请人： Paul Stanley Addison , James Nicholas Watson
发明人： Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B5/02 , A61B8/14
CPC分类号： G06K9/527 , A61B5/14551 , A61B5/6843 , A61B5/726
摘要： According to embodiments, techniques for detecting probe-off events are disclosed. A sensor or probe may be used to obtain a plethysmograph or photoplethysmograph (PPG) signal from a subject. A wavelet transform of the signal may be performed and a scalogram may be generated based at least in part on the wavelet transform. One or more characteristics of the scalogram may be determined. The determined characteristics may include, for example, an energy decrease, a broadscale high-energy cone, a regular, repeated high-scale pattern, a low-scale information pattern; and a pulse band. The absence or presence of these and other characteristics, along with information about the characteristics, may be analyzed to detect a probe-off event. A confidence indicator may be calculated in connection with probe-off event detections and alarms may be generated when probe-off events occur.
摘要翻译：根据实施例，公开了用于检测探测事件的技术。可以使用传感器或探针来获得来自受试者的体积描记器或光电体积描记器（PPG）信号。可以执行信号的小波变换，并且可以至少部分地基于小波变换来生成缩放图。可以确定缩放图的一个或多个特征。确定的特性可以包括例如能量减少，大尺度高能量锥，规则的，重复的高比例图案，低比例的信息图案; 和脉冲带。可以分析这些和其他特征的缺失或存在以及关于特征的信息以检测探测事件。可以结合探测事件检测计算置信指标，并且可以在发生探测事件时生成报警。

9. 发明申请

US20140073962A1 SYSTEM AND METHOD FOR DETERMINING STROKE VOLUME OF A PATIENT 有权
标题翻译：用于确定患者体重的系统和方法
公开(公告)号：US20140073962A1
公开(公告)日：2014-03-13
申请号：US13609566
申请日：2012-09-11
申请人： Paul Stanley Addison , James Nicholas Watson
发明人： Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B6/00
CPC分类号： A61B5/029 , A61B5/024 , A61B5/02416 , A61B5/02427 , A61B5/0261 , A61B5/14551 , A61B5/742 , A61B8/02
摘要： A PPG system for determining a stroke volume of a patient includes a PPG sensor configured to be secured to an anatomical portion of the patient. The PPG sensor is configured to sense a physiological characteristic of the patient. The PPG system may include a monitor operatively connected to the PPG sensor. The monitor receives a PPG signal from the PPG sensor. The monitor includes a pulse trending module determining a slope transit time of an upslope of a primary peak of the PPG signal. The pulse trending module determines a stroke volume of the patient as a function of the slope transit time.
摘要翻译：用于确定患者的行程体积的PPG系统包括被配置为固定到患者的解剖部分上的PPG传感器。 PPG传感器被配置为感测患者的生理特征。 PPG系统可以包括可操作地连接到PPG传感器的监视器。监视器从PPG传感器接收PPG信号。监视器包括确定PPG信号的主峰的上坡的斜率通过时间的脉冲趋势模块。脉冲趋势模块根据斜率通过时间确定患者的搏动量。

10. 发明申请

US20140066732A1 SYSTEM AND METHOD FOR DETERMINING CARDIAC OUTPUT 审中-公开
标题翻译：用于确定心脏输出的系统和方法
公开(公告)号：US20140066732A1
公开(公告)日：2014-03-06
申请号：US13597501
申请日：2012-08-29
申请人： Paul Stanley Addison , James Nicholas Watson
发明人： Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B5/0205 , A61B5/021 , A61B6/00
CPC分类号： A61B5/029 , A61B5/021 , A61B5/1455
摘要： A system is configured to determine cardiac output of a patient. The system may include a first sub-system configured to detect a first physiological signal, and a second sub-system configured to detect a second physiological signal that differs from the first physiological signal. The first and second sub-systems may be separate and distinct from one another. The system may also include a cardiac output determination module that is configured to determine the cardiac output based, at least in part, on the first and second physiological signals.
摘要翻译：系统被配置为确定患者的心输出量。该系统可以包括配置成检测第一生理信号的第一子系统，以及配置成检测不同于第一生理信号的第二生理信号的第二子系统。第一和第二子系统可以是分离的并且彼此不同。该系统还可以包括心输出确定模块，其被配置为至少部分地基于第一和第二生理信号来确定心输出量。

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