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1. 发明授权

US5486457A Method and system for measurement of mechanical properties of molecules and cells 失效
标题翻译：分子和细胞的机械性能测量方法和系统
公开(公告)号：US5486457A
公开(公告)日：1996-01-23
申请号：US112757
申请日：1993-08-25
申请人： James P. Butler , Jeffrey J. Fredberg , Donald E. Ingber , Ning Wang
发明人： James P. Butler , Jeffrey J. Fredberg , Donald E. Ingber , Ning Wang
IPC分类号： G01N24/00 , G01N33/483 , G01N33/487 , G01N35/00 , G01N33/53
CPC分类号： C12M35/06 , C12M41/36 , C12M41/46 , G01N27/745 , G01N24/00 , G01N35/0098 , Y10S436/806 , Y10S436/808
摘要： Mechanical stresses and deformations are applied directly to cell surface receptors or molecules and measured using a system including a magnetic twisting device in combination with ferromagnetic microbeads coated with ligands for integrins or any other surface receptors. The system can be used diagnostically to characterize cells and molecules and to determine the effect of transformation and compounds, including drugs, on the cells and molecules. The system can also be used to induce cells to grow or alter production of molecules by the cells.
摘要翻译：机械应力和变形直接施加到细胞表面受体或分子上，并使用包括磁力扭转装置的系统并与涂覆有用于整联蛋白或任何其它表面受体的配体的铁磁微珠组合来测量。该系统可以在诊断上用于表征细胞和分子，并确定转化和化合物（包括药物）对细胞和分子的影响。该系统还可用于诱导细胞生长或改变细胞的分子产生。

2. 外观设计

USD262365S Vehicle roof hatch frame 失效
公开(公告)号：USD262365S
公开(公告)日：1981-12-22
申请号：US967228
申请日：1978-12-07
申请人： James P. Butler
设计人： James P. Butler

3. 发明申请

US20140155732A1 SYSTEMS AND METHODS FOR PORTABLE MAGNETIC RESONANCE MEASUREMENTS OF LUNG PROPERTIES 审中-公开
标题翻译：用于便携式磁共振测量的系统和方法
公开(公告)号：US20140155732A1
公开(公告)日：2014-06-05
申请号：US14235337
申请日：2012-07-27
申请人： Samuel Patz , Mirko Hrovat , James P. Butler
发明人： Samuel Patz , Mirko Hrovat , James P. Butler
IPC分类号： G01R33/34 , G01R33/565 , G01R33/46 , A61B5/08 , A61B5/055 , A61B5/00
CPC分类号： G01R33/34092 , A61B5/004 , A61B5/055 , A61B5/08 , A61G11/00 , A61G2210/50 , A61M16/021 , A61M2016/0027 , A61M2205/3317 , G01R33/3808 , G01R33/421 , G01R33/5601 , G01R33/565
摘要： A portable magnetic resonance (MR) system for quantitatively measuring properties of a subject's lungs, such as regional ventilation and lung density, is provided. The portable MR system includes a magnet, radio frequency (RF) coil assembly, and spectrometer system. The magnet can be positioned near the subject's chest. The magnetic field of the magnet substantially homogeneous in a region-of-interest located at a distance from the surface of the magnet that localizes the region-of-interest in the subject's lung. The RF coil assembly includes one or more RF coils that are sized to be positioned near the subject's chest, and receives MR signals from the region-of-interest. The spectrometer system controls the RF coil assembly and computes from the acquired MR signals, a quantitative metric indicative of a characteristic of the subject's lung in the region-of-interest. An active noise cancellation system is provided so RF shielding of the portable MR system is not required.
摘要翻译：提供了用于定量测量受试者肺的特性的便携式磁共振（MR）系统，例如区域通气和肺密度。便携式MR系统包括磁体，射频（RF）线圈组件和光谱仪系统。磁铁可以靠近受试者的胸部。位于与磁体表面一定距离处的感兴趣区域中的磁体的磁场基本上均匀，该位置使得受试者的肺中的感兴趣区域定位。 RF线圈组件包括一个或多个RF线圈，其尺寸被定位成靠近被检者的胸部，并且从感兴趣区域接收MR信号。光谱仪系统控制RF线圈组件，并从获得的MR信号中计算出一个指示受试者在感兴趣区域的肺的特征的量度指标。提供了主动噪声消除系统，因此不需要便携式MR系统的RF屏蔽。

4. 发明授权

US5606969A Methods for measuring lung function using diffused light 失效
标题翻译：使用扩散光测量肺功能的方法
公开(公告)号：US5606969A
公开(公告)日：1997-03-04
申请号：US414416
申请日：1995-03-31
申请人： James P. Butler , George P. Topulos , John L. Lehr
发明人： James P. Butler , George P. Topulos , John L. Lehr
IPC分类号： A61B5/00 , G01N21/47
CPC分类号： A61B5/0084 , G01N21/4795 , A61B5/0086
摘要： The method and device of the invention provides a measure of lung function at a preselected region of the lung by detecting and measuring light scattering following contact of the light onto lung tissue. Multiple parameters concerning the status of the lungs can be measured using a variety of wavelengths of light targeted at the lung tissue. In this way it is possible to determine regions of impaired lung function in patients with emphysema. The device utilizes an optical fiber, a light collection system and a spectral separation device to provide an image of the lung and to determine functional parameters such as gas exchange.
摘要翻译：本发明的方法和装置通过在将光接触肺组织之后检测和测量光散射来提供在肺的预选区域的肺功能的量度。关于肺状态的多个参数可以使用靶向肺组织的各种波长的光来测量。以这种方式，可以确定肺气肿患者肺功能受损区域。该装置利用光纤，光收集系统和光谱分离装置来提供肺的图像并确定诸如气体交换的功能参数。

5. 发明授权

US5002284A Balloon bounce game 失效
标题翻译：气球反弹游戏
公开(公告)号：US5002284A
公开(公告)日：1991-03-26
申请号：US586696
申请日：1990-09-24
申请人： Richard P. Butler , James P. Butler
发明人： Richard P. Butler , James P. Butler
IPC分类号： A63B63/00 , A63B67/00 , A63C19/04
CPC分类号： A63C19/04 , A63B67/002 , A63B63/007
摘要： A balloon bounce game suitable for use indoors, includes a generally rectangular mat of flexible material for defining a playing surface, the mat having first indicia for defining a center line that divides the playing surface into two equal area play fields, and second indicia for defining score areas in each of the play fields. The mat is of such dimensions as to enable the mat to be placed on a floor indoors, and for a player located in a serve zone behind a far end of one of the play fields to hit or strike a balloon over the center line to bounce or land in a score field in the other one of the play fields. The form and positions of the indicia therefore make a vertical net unnecessary.
摘要翻译：适合在室内使用的气球反弹游戏包括用于定义游戏表面的大体上矩形的柔性材料垫，该垫具有用于限定将播放表面划分成两个相等区域游戏场的中心线的第一标记，以及用于定义每个场地的得分区域。垫子具有如下尺寸：使得垫可以放置在室内的地板上，并且对于位于一个游戏区域的远端的服务区域中的玩家在中心线上击打或击打气球以反弹或者在另一个游戏场中的得分区域中登陆。因此，标记的形式和位置使得不需要垂直网。

6. 外观设计

USD259633S Vehicle console unit 失效
公开(公告)号：USD259633S
公开(公告)日：1981-06-23
申请号：US956077
申请日：1978-10-30
申请人： James P. Butler
设计人： James P. Butler

7. 发明授权

US08775215B1 Systems and methods for insurance claims settlements 有权
标题翻译：保险理赔系统和方法
公开(公告)号：US08775215B1
公开(公告)日：2014-07-08
申请号：US12177544
申请日：2008-07-22
申请人： James P. Butler , Connie T. Niebling , Sha L. Appenzeller , Ericka K. Fuhrmann
发明人： James P. Butler , Connie T. Niebling , Sha L. Appenzeller , Ericka K. Fuhrmann
IPC分类号： G06Q40/00
CPC分类号： G06Q10/10 , G06F19/00 , G06F19/328 , G06Q40/08 , G06Q50/22
摘要： Systems and methods for insurance claims processing are provided. A system for processing insurance claims may comprise at least one subsystem that makes an automatic assignment of a project to a loss services provider via a selection of an item on a user interface, and at least one subsystem that incorporates information from a report from the loss services provider into a database without manual retyping of said information from the report.
摘要翻译：提供了保险理赔处理的系统和方法。用于处理保险索赔的系统可以包括至少一个子系统，其通过在用户界面上的项目的选择来自动地将项目分配给损失服务提供者，以及至少一个子系统，其包含来自丢失的报告的信息服务提供商转换为数据库，而无需从报告中手动重新输入所述信息。

8. 发明申请

US20130281830A1 System and Method for Improved Lung Fourier Decomposition Magnetic Resonance Imaging 有权
标题翻译：改进肺部傅里叶分解磁共振成像的系统和方法
公开(公告)号：US20130281830A1
公开(公告)日：2013-10-24
申请号：US13453493
申请日：2012-04-23
申请人： Samuel Patz , James P. Butler
发明人： Samuel Patz , James P. Butler
IPC分类号： A61B5/0205 , A61B5/091 , A61B5/055
CPC分类号： A61B5/055 , A61B5/004 , A61B5/0205 , A61B5/024 , A61B5/0263 , A61B5/0816 , A61B5/7257 , A61B2576/02
摘要： A system and method for producing a more accurate ventilation image, as compared to existing lung Fourier decomposition methods, and an image of ventilation dependent blood volume are provided. A time series of images depicting a subject's lungs during free-breathing are acquired and co-registered to a reference image. From the registration process, geometric information indicative proton density changes due to inhalation and exhalation of gas is obtained. This geometric information is used to correct the proton density values in the time series of image frames. These corrected proton density values are Fourier transformed to produce a Fourier spectrum, from which a signal peak occurring at the breathing frequency is extracted and Fourier transformed to produce a more accurate ventilation image. This more accurate ventilation image can be subtracted from a breathing frequency image produced by conventional lung Fourier decomposition methods to produce a ventilation dependent blood volume image.
摘要翻译：提供了与现有的肺部傅立叶分解方法相比，用于产生更准确的通气图像的系统和方法以及通气依赖血液量的图像。获取在自由呼吸期间描绘受试者的肺的时间序列图像并共同登记到参考图像。从注册过程中，获得指示由于吸入和气体呼气引起的质子密度变化的几何信息。该几何信息用于校正图像帧的时间序列中的质子密度值。这些校正的质子密度值被傅里叶变换以产生傅里叶谱，从其中提取在呼吸频率处出现的信号峰，并进行傅立叶变换以产生更准确的通气图像。可以从由常规肺傅里叶分解方法产生的呼吸频率图像中减去更准确的通气图像，以产生通气依赖性血容量图像。

9. 发明授权

US4320919A Aerodynamic visor 失效
标题翻译：气动遮阳板
公开(公告)号：US4320919A
公开(公告)日：1982-03-23
申请号：US971649
申请日：1978-12-21
申请人： James P. Butler
发明人： James P. Butler
IPC分类号： B62D35/00
CPC分类号： B62D35/001
摘要： A visor for automotive use including a plurality of air directing channels for reducing the aerodynamic drag of the visor. The visor is formed from a single sheet of material and the channels are formed by flat bottomed depressions beginning near the front edge of the visor and becoming progressively deeper to a point near the back edge of the visor. From this point, the bottom of the depression abruptly rises back to the visor surface. The depressions have a maximum width near the front edge and taper to half this width near the back edge of the visor. The channels direct air from under the visor through openings formed between the visor and the vehicle and exhaust the air with essentially laminar flow.
摘要翻译：一种用于汽车用途的遮阳板，包括多个空气引导通道，用于减少遮阳板的气动阻力。遮阳板由单张材料形成，通道由靠近遮阳板前边缘的平底凹陷形成，并逐渐变深到靠近遮阳板后边缘的一个点。从这一点来看，凹陷的底部突然上升回遮阳板表面。凹陷在前边缘附近具有最大宽度，并在遮阳板的后边缘附近逐渐变窄到该宽度的一半。通道通过形成在遮阳板和车辆之间的开口将空气从遮阳板下方引导，并以基本层流排出空气。

10. 外观设计

USD261500S Vehicle visor 失效
公开(公告)号：USD261500S
公开(公告)日：1981-10-27
申请号：US966470
申请日：1978-12-04
申请人： James P. Butler
设计人： James P. Butler

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