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1. 发明申请

US20080090782A1 Materials and methods to potentiate cancer treatment 失效
标题翻译：加强癌症治疗的材料和方法
公开(公告)号：US20080090782A1
公开(公告)日：2008-04-17
申请号：US11708163
申请日：2007-02-16
申请人： James Halbrook , Edward Kesicki , Laurence Burgess , Stephen Schlachter , Charles Eary , Justin Schiro , Hongmei Huang , Michael Evans , Yongxin Han
发明人： James Halbrook , Edward Kesicki , Laurence Burgess , Stephen Schlachter , Charles Eary , Justin Schiro , Hongmei Huang , Michael Evans , Yongxin Han
IPC分类号： A61K31/5375 , A61K31/5377 , A61K31/54 , A61K31/675 , A61P35/00 , C07D265/30 , C07D279/12 , C07D413/10 , C07D413/14
CPC分类号： C07D213/40 , A61K45/06 , C07C309/66 , C07D209/36 , C07D211/42 , C07D211/46 , C07D213/50 , C07D213/74 , C07D213/75 , C07D231/12 , C07D233/56 , C07D235/26 , C07D239/48 , C07D249/08 , C07D277/24 , C07D277/54 , C07D279/12 , C07D295/096 , C07D295/112 , C07D295/13 , C07D295/135 , C07D295/155 , C07D295/185 , C07D295/215 , C07D295/30 , C07D307/83 , C07D309/10 , C07D311/30 , C07D333/22 , C07D405/04 , C07D417/12 , C07F9/6533 , C07F9/65785
摘要： Compounds that inhibit DNA-dependent protein kinase, compositions comprising the compounds, methods to inhibit the DNA-PK biological activity, methods to sensitize cells the agents that cause DNA lesions, and methods to potentiate cancer treatment are disclosed.
摘要翻译：公开了抑制DNA依赖性蛋白激酶的化合物，包含该化合物的组合物，抑制DNA-PK生物活性的方法，使细胞致敏引起DNA病变的药剂，以及加强癌症治疗的方法。

2. 发明授权

US07179912B2 Materials and methods to potentiate cancer treatment 有权
标题翻译：加强癌症治疗的材料和方法
公开(公告)号：US07179912B2
公开(公告)日：2007-02-20
申请号：US09941897
申请日：2001-08-28
申请人： James Halbrook , Edward A. Kesicki , Laurence E. Burgess , Stephen T. Schlachter , Charles T. Eary , Justin G. Schiro , Hongmei Huang , Michael Evans , Yongxin Han
发明人： James Halbrook , Edward A. Kesicki , Laurence E. Burgess , Stephen T. Schlachter , Charles T. Eary , Justin G. Schiro , Hongmei Huang , Michael Evans , Yongxin Han
IPC分类号： C07D265/30 , C07D295/02
CPC分类号： C07D213/40 , A61K45/06 , C07C309/66 , C07D209/36 , C07D211/42 , C07D211/46 , C07D213/50 , C07D213/74 , C07D213/75 , C07D231/12 , C07D233/56 , C07D235/26 , C07D239/48 , C07D249/08 , C07D277/24 , C07D277/54 , C07D279/12 , C07D295/096 , C07D295/112 , C07D295/13 , C07D295/135 , C07D295/155 , C07D295/185 , C07D295/215 , C07D295/30 , C07D307/83 , C07D309/10 , C07D311/30 , C07D333/22 , C07D405/04 , C07D417/12 , C07F9/6533 , C07F9/65785
摘要： Compounds that inhibit DNA-dependent protein kinase, compositions comprising the compounds, methods to inhibit the DNA-PK biological activity, methods to sensitize cells the agents that cause DNA lesions, and methods to potentiate cancer treatment are disclosed.
摘要翻译：公开了抑制DNA依赖性蛋白激酶的化合物，包含该化合物的组合物，抑制DNA-PK生物活性的方法，使细胞致敏引起DNA病变的药剂，以及加强癌症治疗的方法。

3. 发明授权

US08242115B2 Materials and methods to potentiate cancer treatment 失效
标题翻译：加强癌症治疗的材料和方法
公开(公告)号：US08242115B2
公开(公告)日：2012-08-14
申请号：US11708163
申请日：2007-02-16
申请人： James Halbrook , Edward A. Kesicki , Laurence E. Burgess , Stephen T. Schlachter , Charles T. Eary , Justin G. Schiro , Hongmei Huang , Michael Evans , Yongxin Han
发明人： James Halbrook , Edward A. Kesicki , Laurence E. Burgess , Stephen T. Schlachter , Charles T. Eary , Justin G. Schiro , Hongmei Huang , Michael Evans , Yongxin Han
IPC分类号： C07D311/86 , C07D405/04 , C07D219/06 , C07D219/16 , C07D401/06 , C07D405/12 , C07D471/04 , A61K31/35
CPC分类号： C07D213/40 , A61K45/06 , C07C309/66 , C07D209/36 , C07D211/42 , C07D211/46 , C07D213/50 , C07D213/74 , C07D213/75 , C07D231/12 , C07D233/56 , C07D235/26 , C07D239/48 , C07D249/08 , C07D277/24 , C07D277/54 , C07D279/12 , C07D295/096 , C07D295/112 , C07D295/13 , C07D295/135 , C07D295/155 , C07D295/185 , C07D295/215 , C07D295/30 , C07D307/83 , C07D309/10 , C07D311/30 , C07D333/22 , C07D405/04 , C07D417/12 , C07F9/6533 , C07F9/65785
摘要： Compounds that inhibit DNA-dependent protein kinase, compositions comprising the compounds, methods to inhibit the DNA-PK biological activity, methods to sensitize cells the agents that cause DNA lesions, and methods to potentiate cancer treatment are disclosed.
摘要翻译：公开了抑制DNA依赖性蛋白激酶的化合物，包含该化合物的组合物，抑制DNA-PK生物活性的方法，使细胞致敏引起DNA病变的药剂，以及加强癌症治疗的方法。

4. 发明申请

US20140338571A1 AGGREGATES 审中-公开
标题翻译：聚集
公开(公告)号：US20140338571A1
公开(公告)日：2014-11-20
申请号：US14368337
申请日：2012-12-21
申请人： Michael EVANS
发明人： Michael Evans
IPC分类号： C04B18/02 , C03C11/00 , C04B18/10 , C04B38/02 , C04B18/06 , C04B18/30 , C03C10/00 , C04B41/50
CPC分类号： C04B18/027 , C03C10/0063 , C03C11/00 , C03C2204/00 , C04B18/023 , C04B18/06 , C04B18/10 , C04B18/305 , C04B28/02 , C04B38/02 , C04B41/5027 , Y02W30/91 , Y02W30/92 , Y02W30/94 , Y02W30/97 , C04B12/04 , C04B14/22 , C04B14/26 , C04B18/04 , C04B18/0463 , C04B18/14 , C04B18/24 , C04B20/1055 , C04B22/0013 , C04B22/16 , C04B24/10 , C04B18/101 , C04B18/103 , C04B18/144
摘要： A method of forming an aggregate. The method comprising forming a green pellet including waste glass and additive(s). The unfired pellets are coated with a refractory material and sintered such that some of the additive/additives breaks down to generate gas which is at least partially retained in the microstructure of the mixture to form pores, the additive/additives so being that upon heating the additive/additives and glass combine to produce glass ceramics.
摘要翻译：一种形成骨料的方法。该方法包括形成包括废玻璃和添加剂的生丸。未烧制的颗粒用耐火材料涂覆并烧结，使得一些添加剂/添加剂分解以产生至少部分地保留在混合物的微结构中以形成孔的气体，添加剂/添加剂使得在加热添加剂/添加剂和玻璃结合生产玻璃陶瓷。

5. 发明申请

US20120166087A1 Method of Determining Density of Underground Formations Using Neutron-Gamma Ray Measurements 有权
标题翻译：使用中子伽马射线测量法确定地层密度的方法
公开(公告)号：US20120166087A1
公开(公告)日：2012-06-28
申请号：US13262643
申请日：2010-04-14
申请人： Michael Evans
发明人： Michael Evans
IPC分类号： G06F19/00 , G01V5/10
CPC分类号： G01V5/101
摘要： A method of determining the density of an underground formation surrounding a borehole from measurement of gamma rays arising from irradiation of the formation by a nuclear source in a tool body located in the borehole, and measurement of gamma-ray flux in the tool body at two different detector spacings from the source, the method comprising determining a substantially straight-line relationship between gamma-ray flux measurements at each different spacing with respect to the density of the formation for a tool body with no standoff; determining a relationship defining the deviation with respect to tool standoff of the density determined from the measured gamma-ray flux measurements at the two different detector spacings from the density calculated from the straight line relationships; and for a given pair of gamma-ray flux measurements at the different detector spacings, determining the intersection of the relationship defining the deviation with the straight line relationship so as to indicate the density of the formation surrounding the bore-hole; wherein the source is a neutron source and the gamma rays measured in the too! body are neutron-induced gamma rays resulting from neutron irradiation of the formation.
摘要翻译：一种通过从位于钻孔中的工具体中的核源照射产生的伽马射线的测量来确定钻孔周围地下地层的密度的方法，以及在两个工具体中测量γ射线通量与源不同的检测器间隔，该方法包括确定在每个不同间隔处的伽马射线通量测量值相对于没有间隙的工具主体的密度的基本上的直线关系; 确定相对于从两个不同检测器间隔处测量的伽马射线通量测量值与从直线关系计算的密度确定的密度的刀具间隔的界定的关系; 并且对于在不同检测器间距处的给定的一对伽马射线通量测量，确定限定偏差的关系与直线关系的交点，以指示围绕钻孔的地层的密度; 其中源是中子源，伽马射线也在测量中！身体是由地层的中子照射产生的中子诱导的γ射线。

6. 发明授权

US08185280B2 Method and apparatus for shifting gears in transmissions 有权
标题翻译：用于在变速器中换档的方法和装置
公开(公告)号：US08185280B2
公开(公告)日：2012-05-22
申请号：US12003004
申请日：2007-12-19
申请人： Michael Evans , Simon Conway
发明人： Michael Evans , Simon Conway
IPC分类号： G06F17/00
CPC分类号： F16H61/462 , F16H47/02 , F16H61/0403 , F16H61/47 , F16H2061/047 , F16H2306/44 , F16H2306/48
摘要： A method of changing from a first gear position to a second gear position of a transmission arrangement is disclosed. The arrangement includes a rotatable transmission member, a hydrostatic continuously variable transmission coupled to the transmission member and operable to rotate the transmission member at a first speed, a controller configured to control operation of the hydrostatic continuously variable transmission, and a gear apparatus coupled to the transmission member and configured to be shiftable between at least the first gear position and the second gear position. The method includes controlling the hydrostatic continuously variable transmission, using the controller, to rotate the transmission member at the first speed, and shifting the gear apparatus from the first gear position to the second gear position while the transmission member is rotating at, or converging with, the first speed.
摘要翻译：公开了一种从变速器装置的第一档位改变到第二档位的方法。该装置包括可旋转的传动构件，连接到传动构件并且可操作以以第一速度旋转传动构件的静压无级变速传动装置，配置成控制静液压无级变速器的操作的控制器，以及耦合到传动构件，并且构造成能够在至少第一档位与第二档位之间移动。该方法包括使用控制器控制静液压无级变速器，以一速度旋转变速器构件，并且在传动构件在第一档位转动或与其同步时将齿轮装置从第一档位移动到第二档位，第一速。

7. 发明授权

US07566272B2 Gaming device with offer/acceptance game having offer chosen from multiple formed offers 失效
标题翻译：具有提供/接受游戏的游戏装置具有从多个成形优惠中选择的优惠
公开(公告)号：US07566272B2
公开(公告)日：2009-07-28
申请号：US11853603
申请日：2007-09-11
申请人： Peter Gerrard , Michael Evans , Dov L. Randall , Aaron T. Jones
发明人： Peter Gerrard , Michael Evans , Dov L. Randall , Aaron T. Jones
IPC分类号： A63F9/24
CPC分类号： G07F17/3262 , G07F17/32
摘要： A primary or secondary game for a gaming device. In one embodiment, the player is provided up to three picks, i.e., picks three contestants. The first two contestants both form potential award offers. The game then provides the greater of the two potential award offers to the player as an initial offer. This initial sequence alternatives includes more than two picks, contestants and potential offers. The offer acceptance feature arises after the initial offer. The player must decide whether to keep the initial offer or forego that offer for a final offer. If the player keeps the offer the game provides that initial offer to the player and ends if the player rejects that initial offer, the game proceeds to build a third and final offer, which is then provided to the player automatically.
摘要翻译：游戏设备的主要或次要游戏。在一个实施例中，玩家最多提供三个选择，即选择三个选手。前两名参赛者均形成潜在奖项。游戏然后提供两个潜在的奖励优惠给玩家作为初始报价。这个初始序列替代方案包括两个以上的选择，参赛者和潜在的优惠。报价接受功能在初始报价后出现。玩家必须决定是否保留最终报价或放弃最终报价的报价。如果玩家保持优惠，则游戏向玩家提供初始报价，并且如果玩家拒绝该初始报价，则结束游戏，游戏继续建立第三和最终报价，然后自动提供给玩家。

8. 发明申请

US20090173645A2 Partially Cut Loosefill Package 有权
标题翻译：部分切割松散包装
公开(公告)号：US20090173645A2
公开(公告)日：2009-07-09
申请号：US11581522
申请日：2006-10-16
申请人： Michael Evans , Todd Jenkins , Timothy Schoenenberger , Brian Linstedt , Hugo Eccles , John Youger , Joseph Sexton , Jeffrey Accursi , Christopher Kujawski , Robert O'Grady
发明人： Michael Evans , Todd Jenkins , Timothy Schoenenberger , Brian Linstedt , Hugo Eccles , John Youger , Joseph Sexton , Jeffrey Accursi , Christopher Kujawski , Robert O'Grady
IPC分类号： B65D71/00
CPC分类号： B65D75/5827 , B65D75/5888 , B65D85/07 , E04F21/085
摘要： A package of compressed blowing insulation includes a body of compressed blowing insulation, a bag encapsulating the body of compressed blowing insulation and a slit extending through the package to define a partially divided package.
摘要翻译：一种压缩吹风绝缘体包括一个压缩吹风绝缘体，一个封装压缩吹风绝缘体的袋子，以及一个延伸穿过包装的狭缝，以限定一个部分分开的包装。

9. 发明申请

US20070211916A1 Method Of Detecting A Target With A Cfar Thresholding Function Using Clutter Map Entries 审中-公开
标题翻译：使用杂波映射条目检测具有Cfar阈值函数的目标的方法
公开(公告)号：US20070211916A1
公开(公告)日：2007-09-13
申请号：US10593456
申请日：2005-03-22
申请人： Iain Smith , Adrian Shalley , Adrian Britton , Samantha Lycett , Michael Evans
发明人： Iain Smith , Adrian Shalley , Adrian Britton , Samantha Lycett , Michael Evans
IPC分类号： G06K9/00
CPC分类号： G01S7/2927 , G01S13/04 , G01S13/723
摘要： A method of detecting a target in a scene comprises the steps of (a) obtaining a first data set of data elements which correspond to returns from different parts of the scene; and (b) determining a detection threshold for a part of the scene by reference to data elements corresponding to returns to neighbouring parts of the scene; characterized in that (i) the method further comprises the steps of (c) obtaining a second data set of data elements which correspond only to clutter returns from different parts of the scene; and (d) identifying clutter returns in the first data set by comparing the first and second data sets; and (ii) in step (b), data elements identified in step (d) as corresponding to clutter returns are discounted in determining the detection threshold. The method provides for improved target detection the presence of clutter.
摘要翻译：一种在场景中检测目标的方法包括以下步骤：（a）获得对应于来自场景的不同部分的返回的数据元素的第一数据集; 以及（b）通过参照对应于对场景的相邻部分的返回的数据元素来确定场景的一部分的检测阈值; 其特征在于，（i）所述方法还包括以下步骤：（c）获得仅对应于来自所述场景的不同部分的杂波返回的数据元素的第二数据集; 和（d）通过比较第一和第二数据集来识别第一数据集中的杂波返回; 和（ii）在步骤（b）中，在确定检测阈值时折扣在步骤（d）中识别为与杂波返回相对应的数据元素。该方法提供了改进的目标检测杂波的存在。

10. 发明申请

US20070105747A1 Control of body odours 审中-公开
标题翻译：控制身体气味
公开(公告)号：US20070105747A1
公开(公告)日：2007-05-10
申请号：US10556302
申请日：2004-04-30
申请人： Keith Perring , John Behan , Paula Cawkill , Michael Evans
发明人： Keith Perring , John Behan , Paula Cawkill , Michael Evans
IPC分类号： A61Q13/00
CPC分类号： A61L15/46 , A61L2300/216
摘要： The invention concerns the control of body odours, particularly odours (other than axillary malodour) associated with body fluids and solids, by use of low odour compositions of fragrance materials. The composition of fragrance material preferably includes at least 5 of one or more musks and at least 5% of one or more salicylates.
摘要翻译：本发明涉及通过使用低气味组合物的香料材料来控制身体气味，特别是与体液和固体相关的气味（除了腋窝恶臭之外）。芳香剂材料的组成优选包括至少5个一种或多种麝香和至少5％的一种或多种水杨酸酯。

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