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1. 发明申请

US20130062525A1 Positron Emission Tomography Block Detector Interconnect 有权
标题翻译：正电子发射断层扫描检测器互连
公开(公告)号：US20130062525A1
公开(公告)日：2013-03-14
申请号：US13229797
申请日：2011-09-12
申请人： James Frank Caruba , Niraj K. Doshi , John W. Young , Nan Zhang
发明人： James Frank Caruba , Niraj K. Doshi , John W. Young , Nan Zhang
IPC分类号： G01T1/20 , G01T1/164
CPC分类号： G01T1/1648
摘要： Using standard or “off the shelf” cable to interconnect between the PET block detector and the detector circuit may save substantial costs given the number of PMTs in a PET system. Given space constraints, simple maintenance with reduced risk of disturbing cabling is desired, making ongoing use of standard cabling without adding further cabling desired. To implement digital gain control, a further communication is provided between the PET detector block and the detector circuit. Since the standard cable may not have additional wires for such communications and to reduce timing degradation, the PMT signals are combined, such as generating position and energy signals at the PET detector block. The four PMT signals are reduced to three signals without reduction in function, allowing a fourth twisted pair of wires in a CAT5 cable to be used for digital gain control.
摘要翻译：使用标准或现货电缆在PET块检测器和检测器电路之间进行互连可以节省大量成本，因为PET系统中PMT的数量。鉴于空间限制，需要简单的维护，减少干扰布线的风险，不断增加布线需求，不断使用标准布线。为了实现数字增益控制，在PET检测器块和检测器电路之间提供进一步的通信。由于标准电缆可能没有用于这种通信的附加电线并且减少定时劣化，所以组合PMT信号，例如在PET检测器块处产生位置和能量信号。四个PMT信号减少到三个信号，而不会降低功能，允许CAT5电缆中的第四根双绞线用于数字增益控制。

2. 发明授权

US08735836B2 Positron emission tomography block detector interconnect 有权
标题翻译：正电子发射断层摄影块检测器互连
公开(公告)号：US08735836B2
公开(公告)日：2014-05-27
申请号：US13229797
申请日：2011-09-12
申请人： James Frank Caruba , Niraj K Doshi , John W Young , Nan Zhang
发明人： James Frank Caruba , Niraj K Doshi , John W Young , Nan Zhang
IPC分类号： G01T1/164
CPC分类号： G01T1/1648
摘要： Using standard or “off the shelf” cable to interconnect between the PET block detector and the detector circuit may save substantial costs given the number of PMTs in a PET system. Given space constraints, simple maintenance with reduced risk of disturbing cabling is desired, making ongoing use of standard cabling without adding further cabling desired. To implement digital gain control, a further communication is provided between the PET detector block and the detector circuit. Since the standard cable may not have additional wires for such communications and to reduce timing degradation, the PMT signals are combined, such as generating position and energy signals at the PET detector block. The four PMT signals are reduced to three signals without reduction in function, allowing a fourth twisted pair of wires in a CAT5 cable to be used for digital gain control.
摘要翻译：使用标准或“现成”电缆在PET块检测器和检测器电路之间进行互连可以节省大量成本，因为PET系统中PMT的数量。鉴于空间限制，需要简单的维护，减少干扰布线的风险，不断增加布线需求，不断使用标准布线。为了实现数字增益控制，在PET检测器块和检测器电路之间提供进一步的通信。由于标准电缆可能没有用于这种通信的附加电线并且减少定时劣化，所以组合PMT信号，例如在PET检测器块处产生位置和能量信号。四个PMT信号减少到三个信号而不减少功能，允许CAT5电缆中的第四根双绞线用于数字增益控制。

3. 发明授权

US09086492B2 Concurrent DC-coupled anode and dynode readout scheme for PET block detectors 有权
标题翻译：并联DC耦合阳极和用于PET块检测器的倍增电极读出方案
公开(公告)号：US09086492B2
公开(公告)日：2015-07-21
申请号：US11753067
申请日：2007-05-24
申请人： Nan Zhang , Matthias J. Schmand , Niraj K. Doshi , Michael D. Loope
发明人： Nan Zhang , Matthias J. Schmand , Niraj K. Doshi , Michael D. Loope
IPC分类号： G01T1/00 , G01T1/164
CPC分类号： G01T1/1642 , G01T1/208
摘要： A scintillation detector including one or more photomultiplier tubes, a scintillation block optically attached to the photomultiplier tubes, and a DC-coupled bleeder circuit combining outputs of dynodes of the photomultipliers to provide a DC-coupled dynode output together with a DC-coupled anode output of the photomultiplier tubes. The DC-coupled bleeder circuit includes a RF transformer. A positive high voltage supply also can be used together with a DC-coupled bleeder circuit for the anode outputs.
摘要翻译：闪烁检测器，包括一个或多个光电倍增管，与光电倍增管光学连接的闪烁块，以及组合光电倍增管的倍增电极输出的DC耦合泄放电路，以提供DC耦合的倍增电极输出以及直流耦合的阳极输出的光电倍增管。直流耦合放电电路包括RF变压器。阳极高压电源也可以与阳极输出的直流耦合泄放电路一起使用。

4. 发明授权

US07579599B2 Parameter adjustment for medical device 有权
标题翻译：医疗器械参数调整
公开(公告)号：US07579599B2
公开(公告)日：2009-08-25
申请号：US11941562
申请日：2007-11-16
申请人： Nan Zhang , Volker Matschl , Niraj K. Doshi , Matthias J. Schmand
发明人： Nan Zhang , Volker Matschl , Niraj K. Doshi , Matthias J. Schmand
IPC分类号： G01T1/164
CPC分类号： A61B6/037 , A61B6/56
摘要： A medical device with a high voltage connection line for carrying a high DC supply voltage has a control unit generating said high DC supply voltage which is fed through a first AC block unit to said high voltage connection line and generating a digital control signal fed through a first AC coupling unit to said high voltage connection line, and a remotely located unit a second AC block unit coupled to said high voltage connection line for receiving said high DC supply voltage and a second AC coupling unit coupled to said high voltage connection line for receiving said digital control signal.
摘要翻译：具有用于承载高直流电源电压的高压连接线的医疗装置具有产生所述高直流电源电压的控制单元，所述高直流电源电压通过第一AC块单元馈送到所述高压连接线，并产生通过第一AC耦合单元连接到所述高压连接线，以及远程定位单元，耦合到所述高压连接线的第二AC块单元，用于接收所述高DC电源电压;以及第二AC耦合单元，耦合到所述高压连接线，用于接收所述数字控制信号。

5. 发明授权

US07495222B2 Signal polarity inverting multiplexing circuits for nuclear medical detectors 有权
标题翻译：用于核医学检测器的信号极性反转多路复用电路
公开(公告)号：US07495222B2
公开(公告)日：2009-02-24
申请号：US11751372
申请日：2007-05-21
申请人： Nan Zhang , Matthias J. Schmand , Niraj K. Doshi
发明人： Nan Zhang , Matthias J. Schmand , Niraj K. Doshi
IPC分类号： G01T1/20
CPC分类号： G01T1/1642 , G01T1/1647
摘要： A system for multiplexing photodetector signals from a scintillation detector. The system includes a detector module having a number of scintillator blocks, each scintillator block having a number of photosensors, and a number of multiplexing circuits. Each multiplexing circuit includes a number of inputs, a signal polarity inverter and at least one differential output attached to the signal polarity inverter. The multiplexing system inverts the polarity of preselected signals from the photosensors and selectively combines signals of different polarities to calculate event positioning and total energy.
摘要翻译：一种用于复用来自闪烁检测器的光检测器信号的系统。该系统包括具有多个闪烁体块的检测器模块，每个闪烁体块具有多个光电传感器，以及多个复用电路。每个多路复用电路包括多个输入端，信号极性反相器和附加到信号极性反相器的至少一个差分输出。复用系统将来自光电传感器的预选信号的极性反转，并且选择性地组合不同极性的信号以计算事件定位和总能量。

6. 发明授权

US09006664B2 Encoding for nuclear medical imaging block detectors 有权
标题翻译：核医学成像块检测器的编码
公开(公告)号：US09006664B2
公开(公告)日：2015-04-14
申请号：US13115220
申请日：2011-05-25
申请人： Nan Zhang , Niraj K. Doshi , Matthias J. Schmand
发明人： Nan Zhang , Niraj K. Doshi , Matthias J. Schmand
IPC分类号： G01T1/20
CPC分类号： G01T1/2018
摘要： Signals generated by radiation sensors can be encoded to reduce the number of cables needed to transport information from a nuclear imaging apparatus to a processor for reconstruction. For example, signals from 16 radiation sensors can be encoded into three signals: T (top), L (left), and E (energy). This method of encoding signals can be capable of substantially reducing the number of signals, thereby reducing costs. In addition, reducing the number of signals could improve system timing performance by eliminating cable time-skew and facilitate the filter design by downgrading the circuit accuracy requirements such as group-delay error and filter signal skews.
摘要翻译：可以编码由辐射传感器产生的信号以减少将信息从核成像设备传输到处理器以进行重建所需的电缆数量。例如，来自16个辐射传感器的信号可以被编码成三个信号：T（上），L（左）和E（能量）。这种编码信号的方法能够显着减少信号的数量，从而降低成本。此外，减少信号数量可以通过消除电缆时间偏移来提高系统定时性能，并通过降低电路精度要求（如组延迟误差和滤波器信号偏移）来促进滤波器设计。

7. 发明申请

US20120212355A1 Encoding for Nuclear Medical Imaging Block Detectors 有权
标题翻译：核医学成像检测器编码
公开(公告)号：US20120212355A1
公开(公告)日：2012-08-23
申请号：US13115220
申请日：2011-05-25
申请人： Nan Zhang , Niraj K. Doshi , Matthias J. Schmand
发明人： Nan Zhang , Niraj K. Doshi , Matthias J. Schmand
IPC分类号： H03M7/00 , G01T1/20 , G01T1/00
CPC分类号： G01T1/2018
摘要： Signals generated by radiation sensors can be encoded to reduce the number of cables needed to transport information from a nuclear imaging apparatus to a processor for reconstruction. For example, signals from 16 radiation sensors can be encoded into three signals: T (top), L (left), and E (energy). This method of encoding signals can be capable of substantially reducing the number of signals, thereby reducing costs. In addition, reducing the number of signals could improve system timing performance by eliminating cable time-skew and facilitate the filter design by downgrading the circuit accuracy requirements such as group-delay error and filter signal skews.
摘要翻译：可以编码由辐射传感器产生的信号以减少将信息从核成像设备传输到处理器以进行重建所需的电缆数量。例如，来自16个辐射传感器的信号可以被编码成三个信号：T（上），L（左）和E（能量）。这种编码信号的方法能够显着减少信号的数量，从而降低成本。此外，减少信号数量可以通过消除电缆时间偏移来提高系统定时性能，并通过降低电路精度要求（如组延迟误差和滤波器信号偏移）来促进滤波器设计。

8. 发明申请

US20090072151A1 Parameter Adjustment for Medical Device 有权
标题翻译：医疗器械参数调整
公开(公告)号：US20090072151A1
公开(公告)日：2009-03-19
申请号：US11941562
申请日：2007-11-16
申请人： Nan Zhang , Volker Matschl , Niraj K. Doshi , Matthias J. Schmand
发明人： Nan Zhang , Volker Matschl , Niraj K. Doshi , Matthias J. Schmand
IPC分类号： G01T1/164 , H04B3/54
CPC分类号： A61B6/037 , A61B6/56
摘要： A medical device with a high voltage connection line for carrying a high DC supply voltage has a control unit generating said high DC supply voltage which is fed through a first AC block unit to said high voltage connection line and generating a digital control signal fed through a first AC coupling unit to said high voltage connection line, and a remotely located unit a second AC block unit coupled to said high voltage connection line for receiving said high DC supply voltage and a second AC coupling unit coupled to said high voltage connection line for receiving said digital control signal.
摘要翻译：具有用于承载高直流电源电压的高压连接线的医疗装置具有产生所述高直流电源电压的控制单元，所述高直流电源电压通过第一AC块单元馈送到所述高压连接线，并产生通过第一AC耦合单元连接到所述高压连接线，以及远程定位单元，耦合到所述高压连接线的第二AC块单元，用于接收所述高DC电源电压;以及第二AC耦合单元，耦合到所述高压连接线，用于接收所述数字控制信号。

9. 发明申请

US20080290282A1 Concurrent DC-Coupled Anode and Dynode Readout Scheme For PET Block Detectors 有权
标题翻译：用于PET块检测器的并行DC耦合阳极和Dynode读出方案
公开(公告)号：US20080290282A1
公开(公告)日：2008-11-27
申请号：US11753067
申请日：2007-05-24
申请人： Nan Zhang , Matthias J. Schmand , Niraj K. Doshi , Michael D. Loope
发明人： Nan Zhang , Matthias J. Schmand , Niraj K. Doshi , Michael D. Loope
IPC分类号： G01T1/20
CPC分类号： G01T1/1642 , G01T1/208
摘要： A scintillation detector including one or more photomultiplier tubes, a scintillation block optically attached to the photomultiplier tubes, and a DC-coupled bleeder circuit combining outputs of dynodes of the photomultipliers to provide a DC-coupled dynode output together with a DC-coupled anode output of the photomultiplier tubes. The DC-coupled bleeder circuit includes a RF transformer. A positive high voltage supply also can be used together with a DC-coupled bleeder circuit for the anode outputs.
摘要翻译：闪烁检测器，包括一个或多个光电倍增管，与光电倍增管光学连接的闪烁块，以及组合光电倍增管的倍增电极输出的DC耦合泄放电路，以提供DC耦合的倍增电极输出以及直流耦合的阳极输出的光电倍增管。直流耦合放电电路包括RF变压器。阳极高压电源也可以与阳极输出的直流耦合泄放电路一起使用。

10. 发明授权

US08369928B2 Data processing system for multi-modality imaging 有权
标题翻译：多模态成像数据处理系统
公开(公告)号：US08369928B2
公开(公告)日：2013-02-05
申请号：US12564635
申请日：2009-09-22
申请人： Roger E. Arseneau , James Frank Caruba , Michael E. Casey , Mark Musrock , Nan Zhang
发明人： Roger E. Arseneau , James Frank Caruba , Michael E. Casey , Mark Musrock , Nan Zhang
IPC分类号： A61B5/05
CPC分类号： G01T1/1603 , A61B6/037 , A61B6/5247
摘要： A data processing process and embodiment for optimizing the signal path for multi-modality imaging is described. The embodiment and process optimizes the signal to noise ratio in a positron emission tomography (PET) signal path utilizing scintillation crystals, avalanche photo diodes, and charge sensitive preamplifiers in a dual modality MRI/PET scanner. The dual use of both and analog pole zero circuit and a digital filter enables higher signal levels or a fixed ADC input range and thus a higher possible signal to noise ratio in the presence of significant pileup caused by high positron activity. The higher signal to noise ratio is needed in the PET signal architecture, because of the presence of non-modal time varying electromagnetic fields from the MR, which are a significant source of noise for the wideband PET signal modality.
摘要翻译：描述了用于优化用于多模态成像的信号路径的数据处理过程和实施例。实施例和过程利用双重模式MRI / PET扫描器中的闪烁晶体，雪崩光电二极管和电荷敏感前置放大器在正电子发射断层摄影（PET）信号路径中优化信噪比。双重使用模拟极零电路和数字滤波器可实现更高的信号电平或固定的ADC输入范围，从而在存在由高正电子活动引起的重大堆积的情况下，可能的信噪比更高。在PET信号架构中需要更高的信噪比，因为存在来自MR的非模态时变电磁场，这是对于宽带PET信号模态的噪声的重要来源。

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