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1. 发明授权

US06287783B1 Optical assay device and method 失效
标题翻译：光学测定装置及方法
公开(公告)号：US06287783B1
公开(公告)日：2001-09-11
申请号：US09272641
申请日：1999-03-18
申请人： James E. Maynard , Mark A. Crosby , Alan J. Fujii
发明人： James E. Maynard , Mark A. Crosby , Alan J. Fujii
IPC分类号： G01N3353
CPC分类号： B01L3/5023 , B01L2300/042 , B01L2300/046 , B01L2300/069 , B01L2300/0832 , B01L2400/0406 , Y10S435/808 , Y10S435/81 , Y10S436/805
摘要： The present invention involves an optical assay device and method of use for the detection of an analyte of interest in a sample that conveniently allows control of the flow characteristics of the sample through the device without significant user intervention. The optical assay device includes a base having an absorbent material, and a member having an optically active test stack that is rotatably coupled to the base for rotation between a lowered position and a raised position. In the lowered position, the optically active test stack contacts the absorbent material for drawing the sample through the surface. In the raised position, the optically active test stack does not contact the absorbent material.
摘要翻译：本发明涉及一种用于检测样品中感兴趣的分析物的光学测定装置和方法，其方便地允许通过装置控制样品的流动特性而无需显着的用户干预。该光学测定装置包括具有吸收材料的底座和具有光学活动的测试叠层的构件，其可旋转地联接到基座以在降低位置和升高位置之间旋转。在降低的位置，光学活性测试堆叠接触吸收材料，以将样品通过表面。在升高位置，光学活性测试叠层不接触吸收材料。

2. 外观设计

USD431867S Immunoassay test device 失效
公开(公告)号：USD431867S
公开(公告)日：2000-10-10
申请号：US102418
申请日：1999-03-22
申请人： James E. Maynard , Mark A. Crosby , Alan J. Fujii
设计人： James E. Maynard , Mark A. Crosby , Alan J. Fujii

3. 发明授权

US06770447B2 Optical assay device and method 失效
标题翻译：光学测定装置及方法
公开(公告)号：US06770447B2
公开(公告)日：2004-08-03
申请号：US09905146
申请日：2001-07-12
申请人： James E. Maynard , Mark A. Crosby , Alan J. Fujii
发明人： James E. Maynard , Mark A. Crosby , Alan J. Fujii
IPC分类号： G01N3353
CPC分类号： B01L3/5023 , B01L2300/042 , B01L2300/046 , B01L2300/069 , B01L2300/0832 , B01L2400/0406 , Y10S435/808 , Y10S435/81 , Y10S436/805
摘要： The present invention involves an optical assay device and method of use for the detection of an analyte of interest in a sample that conveniently allows control of the flow characteristics of the sample through the device without significant user intervention. The optical assay device includes a base having an absorbent material, and a member having an optically active test stack that is rotatably coupled to the base for rotation between a lowered position and a raised position. In the lowered position, the optically active test stack contacts the absorbent material for drawing the sample through the surface. In the raised position, the optically active test stack does not contact the absorbent material.
摘要翻译：本发明涉及一种用于检测样品中感兴趣的分析物的光学测定装置和方法，其方便地允许通过装置控制样品的流动特性而无需显着的用户干预。该光学测定装置包括具有吸收材料的底座和具有光学活动的测试叠层的构件，其可旋转地联接到基座以在降低位置和升高位置之间旋转。在降低的位置，光学活性测试堆叠接触吸收材料，以将样品通过表面。在升高位置，光学活性测试叠层不接触吸收材料。

4. 发明授权

US06207445B1 Filtration and extraction device and method of using the same 有权
标题翻译：过滤和提取装置及其使用方法
公开(公告)号：US06207445B1
公开(公告)日：2001-03-27
申请号：US09617394
申请日：2000-07-17
申请人： Mark A. Crosby
发明人： Mark A. Crosby
IPC分类号： C12M100
CPC分类号： B01D29/05 , B01D29/78 , B01D29/822 , B01D35/00 , B01D2201/202 , C12M33/14 , Y10S435/975
摘要： The present invention involves a simple, disposable, manual filtration and extraction device and method of use that provides a sample directly to an analytical method. The device is capable of providing a clarified liquid ready for analysis or disposal as appropriate for the specific analyte of interest, and is capable of capturing particulate materials and allowing for further extraction of those particles directly with the device. Once extracted, the device will deliver a liquid containing the analyte of interest to an analytical method. The filtration and extraction device includes a pliant body having an open top end and an internal wall defining an inner chamber. A sealing mechanism is adapted to seal the open top end of the body. A gradient filter assembly including at least one filter is supported by a support assembly carried by the body. The pliant body is adapted to be squeezed by a user's fingers so as to impart a positive pressure in the chamber sufficient to cause a fluid in the chamber to flow through the filter assembly.
摘要翻译：本发明涉及一种简单的，一次性的，手动的过滤和提取装置以及将样品直接提供给分析方法的使用方法。该装置能够提供适合于感兴趣的特定分析物的分析或处理的澄清液体，并且能够捕获颗粒材料并允许直接用该装置进一步提取那些颗粒。一旦提取，装置将输送含有目的分析物的液体到分析方法。过滤和提取装置包括具有开口顶端和限定内室的内壁的柔韧体。密封机构适于密封身体的敞开的顶端。包括至少一个过滤器的梯度过滤器组件由主体承载的支撑组件支撑。柔顺的身体适于被使用者的手指挤压，以便在腔室中施加足够的正压力使得腔室中的流体流过过滤器组件。

5. 发明授权

US6090572A Filtration and extraction device and method of using the same 失效
标题翻译：过滤和提取装置及其使用方法
公开(公告)号：US6090572A
公开(公告)日：2000-07-18
申请号：US105309
申请日：1998-06-26
申请人： Mark A. Crosby
发明人： Mark A. Crosby
IPC分类号： G01N33/48 , B01D11/02 , B01D29/05 , B01D35/00 , B01D35/02 , B01D39/16 , B01D63/08 , B01D69/06 , B01D71/10 , B01D71/12 , B01D71/16 , B01D71/26 , B01D71/56 , B01D71/68 , C12M1/12 , C12M1/40 , G01N1/04 , G01N1/10 , G01N33/493 , G01N33/531 , G01N33/543 , G01N33/569 , G01N33/68 , C12Q1/02 , C12Q1/00 , C12Q1/37 , C12Q1/04
CPC分类号： B01D29/05 , B01D35/00 , C12M33/14 , B01D2201/202 , Y10S435/975
摘要： The present invention involves a simple, disposable, manual filtration and extraction device and method of use that provides a sample directly to an analytical method. The device is capable of providing a clarified liquid ready for analysis or disposal as appropriate for the specific analyte of interest, and is capable of capturing particulate materials and allowing for further extraction of those particles directly with the device. Once extracted, the device will deliver a liquid containing the analyte of interest to an analytical method. The filtration and extraction devise includes a pliant body having an open top end and an internal wall defining an inner chamber. A sealing mechanism is adapted to seal the open top end of the body. A gradient filter assembly including at least one filter is supported by a support assembly carried by the body. The pliant body is adapted to be squeezed by a user's fingers so as to impart a positive pressure in the chamber sufficient to cause a fluid in the chamber to flow through the filter assembly.
摘要翻译：本发明涉及一种简单的，一次性的，手动的过滤和提取装置以及将样品直接提供给分析方法的使用方法。该装置能够提供适合于感兴趣的特定分析物的分析或处理的澄清液体，并且能够捕获颗粒材料并允许直接用该装置进一步提取那些颗粒。一旦提取，装置将输送含有目的分析物的液体到分析方法。过滤和提取设备包括具有开口顶端和限定内室的内壁的柔韧体。密封机构适于密封身体的敞开的顶端。包括至少一个过滤器的梯度过滤器组件由主体承载的支撑组件支撑。柔顺的身体适于被使用者的手指挤压，以便在腔室中施加足够的正压力使得腔室中的流体流过过滤器组件。

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