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1. 发明申请

US20050273479A1 Reformulation of the finite-difference time-domain algorithm for hardware-based accelerators 有权
标题翻译：重构基于硬件的加速器的有限差分时域算法
公开(公告)号：US20050273479A1
公开(公告)日：2005-12-08
申请号：US11100861
申请日：2005-04-07
申请人： James Durbano , John Humphrey , Fernando Ortiz , Dennis Prather , Mark Mirotznik
发明人： James Durbano , John Humphrey , Fernando Ortiz , Dennis Prather , Mark Mirotznik
IPC分类号： G06F7/00 , G06F17/50
CPC分类号： G06F17/5018
摘要： A hardware-based acceleration platform for computational electromagnetic algorithms, specifically the finite-difference time-domain (“FDTD”) method, comprises reformulating the FDTD algorithm in order to make it more hardware friendly. This reformulation makes use of split fields at every node in the mesh, and combines total- and scattered-field formulations into a single, hybrid formulation. By precomputing coefficients for the nodes in the mesh, it is possible for a single set of equations to support plane waves, point sources, PML ABCs, and PEC walls. In the method sources are determined by means of a lookup table, rather than through direct hardware computations. All of these modifications enable the hardware designer to much more easily develop an FDTD accelerator.
摘要翻译：用于计算电磁算法的硬件加速平台，特别是有限差分时域（“FDTD”）方法，包括重新配置FDTD算法，使其更加硬件友好。这种重新设计利用网格中每个节点的分割场，并将总场分布和散射场拟合组合成单个混合公式。通过预先计算网格中节点的系数，单个方程组可以支持平面波，点源，PML ABC和PEC墙。在方法中，源通过查找表而不是通过直接硬件计算来确定。所有这些修改使得硬件设计人员能够更容易地开发FDTD加速器。

2. 发明授权

US5502386A Pulsed low frequency EPR spectrometer and imager 失效
公开(公告)号：US5502386A
公开(公告)日：1996-03-26
申请号：US340100
申请日：1994-11-15
申请人： John Bourg , James Mitchell , Mark Mirotznik , Bradley Roth , Sankaran Subramanian , Murali Cherukuri , Paul G. Zablocky , Thomas J. Pohida , Paul D. Smith , Walter S. Friauf , Rolf G. Tschudin
发明人： John Bourg , James Mitchell , Mark Mirotznik , Bradley Roth , Sankaran Subramanian , Murali Cherukuri , Paul G. Zablocky , Thomas J. Pohida , Paul D. Smith , Walter S. Friauf , Rolf G. Tschudin
IPC分类号： G01R33/20 , A61B5/055 , G01N24/10 , G01R33/60
CPC分类号： G01R33/60
摘要： An EPR imager and spectrometer includes pulse generating system for generating broadband pulses having an RF carrier frequency that is not highly absorbed by biological samples. The pulse generating system includes up and down chirp convertors for frequency modulating a carrier frequency pulse and compressing the frequency modulated pulse to form a broadband excitation pulse of high energy. Such a machine could form the basis of a clinical imaging device capable of high sensitivity to free radical species in human patients.

3. 发明授权

US07997732B2 Lenslet array for retinal oximetry 有权
标题翻译：用于视网膜血氧饱和度的Lenslet阵列
公开(公告)号：US07997732B2
公开(公告)日：2011-08-16
申请号：US12262696
申请日：2008-10-31
申请人： Jessica C. Ramella-Roman , Mark Mirotznik , Scott A. Mathews
发明人： Jessica C. Ramella-Roman , Mark Mirotznik , Scott A. Mathews
IPC分类号： A61B3/10 , A61B3/14 , G02B27/10
CPC分类号： A61B5/14555 , G02B3/0056 , G02B5/201 , G02B27/28
摘要： The multi-aperture system of the present invention provides a retinal oximetry apparatus for determining the level of oxygen saturation in retinal vessels using a lenslet array comprising at least seven lenses for the simultaneous measurement of reflected light with at least three wavelengths and at least four polarization states. The multi-aperture system of the present invention further provides an apparatus for determining the level of oxygen saturation in retinal vessels using a lenslet array comprising at least ten lenses for the simultaneous measurement of reflected light with at least three wavelengths for oxygen measurement, at least three wavelengths for melanin content, and at least four polarization states. Methods of operating the same are also provided.
摘要翻译：本发明的多孔径系统提供一种视网膜血氧测定装置，用于使用包括至少七个透镜的小透镜阵列来确定视网膜血管中的氧饱和度水平，用于同时测量具有至少三个波长的反射光和至少四个极化状态。本发明的多孔径系统还提供一种用于使用包括至少十个透镜的小透镜阵列来确定视网膜血管中的氧饱和度的装置，用于同时测量具有至少三个波长的用于氧测量的反射光，至少三个波长的黑色素含量和至少四个极化状态。还提供了其操作方法。

4. 发明授权

US08308299B2 Lenslet array for retinal oximetry 失效
标题翻译：用于视网膜血氧饱和度的Lenslet阵列
公开(公告)号：US08308299B2
公开(公告)日：2012-11-13
申请号：US13177742
申请日：2011-07-07
申请人： Jessica C. Ramella-Roman , Scott A. Mathews , Mark Mirotznik
发明人： Jessica C. Ramella-Roman , Scott A. Mathews , Mark Mirotznik
IPC分类号： A61B3/00 , A61B3/14 , A61B3/10 , G02B27/10
CPC分类号： A61B5/14555 , G02B3/0056 , G02B5/201 , G02B27/28
摘要： The multi-aperture system of the present invention provides a retinal oximetry apparatus for determining the level of oxygen saturation in retinal vessels using a lenslet array comprising at least seven lenses for the simultaneous measurement of reflected light with at least three wavelengths and at least four polarization states. The multi-aperture system of the present invention further provides an apparatus for determining the level of oxygen saturation in retinal vessels using a lenslet array comprising at least ten lenses for the simultaneous measurement of reflected light with at least three wavelengths for oxygen measurement, at least three wavelengths for melanin content, and at least four polarization states. Methods of operating the same are also provided.
摘要翻译：本发明的多孔径系统提供一种视网膜血氧测定装置，用于使用包括至少七个透镜的小透镜阵列来确定视网膜血管中的氧饱和度水平，用于同时测量具有至少三个波长的反射光和至少四个极化状态。本发明的多孔径系统还提供一种用于使用包括至少十个透镜的小透镜阵列来确定视网膜血管中的氧饱和度的装置，用于同时测量具有至少三个波长的用于氧测量的反射光，至少三个波长的黑色素含量和至少四个极化状态。还提供了其操作方法。

5. 发明申请

US20110261321A1 LENSLET ARRAY FOR RETINAL OXIMETRY 失效
公开(公告)号：US20110261321A1
公开(公告)日：2011-10-27
申请号：US13177742
申请日：2011-07-07
申请人： Jessica C. RAMELLA-ROMAN , Mark Mirotznik , Scott A. Mathews
发明人： Jessica C. RAMELLA-ROMAN , Mark Mirotznik , Scott A. Mathews
IPC分类号： A61B3/14
CPC分类号： A61B5/14555 , G02B3/0056 , G02B5/201 , G02B27/28
摘要： The multi-aperture system of the present invention provides a retinal oximetry apparatus for determining the level of oxygen saturation in retinal vessels using a lenslet array comprising at least seven lenses for the simultaneous measurement of reflected light with at least three wavelengths and at least four polarization states. The multi-aperture system of the present invention further provides an apparatus for determining the level of oxygen saturation in retinal vessels using a lenslet array comprising at least ten lenses for the simultaneous measurement of reflected light with at least three wavelengths for oxygen measurement, at least three wavelengths for melanin content, and at least four polarization states. Methods of operating the same are also provided.
摘要翻译：本发明的多孔径系统提供一种视网膜血氧测定装置，用于使用包括至少七个透镜的小透镜阵列来确定视网膜血管中的氧饱和度水平，用于同时测量具有至少三个波长的反射光和至少四个极化状态。本发明的多孔径系统还提供一种用于使用包括至少十个透镜的小透镜阵列来确定视网膜血管中的氧饱和度的装置，用于同时测量具有至少三个波长的用于氧测量的反射光，至少三个波长的黑色素含量和至少四个极化状态。还提供了其操作方法。

6. 发明授权

US5387867A Pulsed low frequency EPR spectrometer and imager 失效
标题翻译：脉冲低频EPR光谱仪和成像仪
公开(公告)号：US5387867A
公开(公告)日：1995-02-07
申请号：US97811
申请日：1993-07-26
申请人： John Bourg , James Mitchell , Mark Mirotznik , Bradley Roth , Sankaran Subramanian , Murali Cherukuri , Paul G. Zablocky
发明人： John Bourg , James Mitchell , Mark Mirotznik , Bradley Roth , Sankaran Subramanian , Murali Cherukuri , Paul G. Zablocky
IPC分类号： G01R33/20 , A61B5/055 , G01N24/10 , G01R33/60
CPC分类号： G01R33/60
摘要： An EPR imager and spectrometer includes pulse generating system for generating broadband pulses having an RF carrier frequency that is not highly absorbed by biological samples. The pulse generating system includes up and down chirp convertors for frequency modulating a carrier frequency pulse and compressing the frequency modulated pulse to form a broadband excitation pulse of high energy. Such a machine could form the basis of a clinical imaging device capable of high sensitivity to free radical species in human patients.
摘要翻译： EPR成像器和光谱仪包括用于产生具有不被生物样品高度吸收的RF载波频率的宽带脉冲的脉冲发生系统。脉冲发生系统包括用于频率调制载波频率脉冲的上和下啁啾转换器，并压缩频率调制脉冲以形成高能量的宽带激励脉冲。这种机器可以形成能够对人类患者中的自由基物质具有高度敏感性的临床成像装置的基础。

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