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1. 发明申请

US20090268952A1 METHOD AND APPARATUS FOR AUTOMATICALLY DEVELOPING A HIGH PERFORMANCE CLASSIFIER FOR PRODUCING MEDICALLY MEANINGFUL DESCRIPTORS IN MEDICAL DIAGNOSIS IMAGING 有权
标题翻译：用于自动开发用于在医学诊断成像中生产医学意义描述符的高性能分类器的方法和装置
公开(公告)号：US20090268952A1
公开(公告)日：2009-10-29
申请号：US11721999
申请日：2005-12-13
申请人： James David Schaffer , Walid Ali , Larry Eshelman , Claude Cohen-Bacrie , Jean-Michel Lagrange , Claire Levrier , Nicolas Francois Villain , Robert Randall Entrekin
发明人： James David Schaffer , Walid Ali , Larry Eshelman , Claude Cohen-Bacrie , Jean-Michel Lagrange , Claire Levrier , Nicolas Francois Villain , Robert Randall Entrekin
IPC分类号： G06K9/00
CPC分类号： G06K9/6217
摘要： A method for determining the presence or absence of malignant features in medical images, wherein a plurality of base comparison or training images of various types of lesions taken of actual patient is examined by one or more image reading experts to create a first database array. Low-level features of each of the lesions in the same plurality of base comparisons or training images arc determined using one or more image processing algorithms to obtain a second database array set. The first and second database array set are combined to create a training database array set which is input to a learning system that discovers/learns a classifier that maps from a subset of the low-level features to the expert's evaluation in the first database array set. The classifier is used to determine the presence of a particular mid-level feature in an image of lesion in a patient based solely on the image.
摘要翻译：一种用于确定医学图像中恶性特征的存在或不存在的方法，其中由一个或多个图像读取专家检查由实际患者取得的各种类型的损伤的多个基础比较或训练图像以创建第一数据库阵列。使用一个或多个图像处理算法确定相同多个基本比较或训练图像中的每个病变的低级特征以获得第二数据库阵列集。组合第一和第二数据库阵列组以创建训练数据库阵列集合，其被输入到发现/学习从低级特征的子集映射到第一数据库阵列集合中的专家评估的分类器的学习系统。分类器用于仅基于图像来确定患者的病变图像中特定中级特征的存在。

2. 发明授权

US08208697B2 Method and apparatus for automatically developing a high performance classifier for producing medically meaningful descriptors in medical diagnosis imaging 有权
标题翻译：用于自动开发用于在医学诊断成像中产生医学上有意义的描述符的高性能分类器的方法和装置
公开(公告)号：US08208697B2
公开(公告)日：2012-06-26
申请号：US11721999
申请日：2005-12-13
申请人： James David Schaffer , Walid Ali , Larry J. Eshelman , Claude Cohen-Bacrie , Jean-Michel Lagrange , Claire Levrier , Nicholas Villain , Robert R. Entrekin
发明人： James David Schaffer , Walid Ali , Larry J. Eshelman , Claude Cohen-Bacrie , Jean-Michel Lagrange , Claire Levrier , Nicholas Villain , Robert R. Entrekin
IPC分类号： G06K9/36
CPC分类号： G06K9/6217
摘要： A method for determining the presence or absence of malignant features in medical images, wherein a plurality of base comparison or training images of various types of lesions taken of actual patient is examined by one or more image reading experts to create a first database array. Low-level features of each of the lesions in the same plurality of base comparisons or training images are determined using one or more image processing algorithms to obtain a second database array set. The first and second database array set are combined to create a training database array set which is input to a learning system that discovers/learns a classifier that maps from a subset of the low-level features to the expert's evaluation in the first database array set. The classifier is used to determine the presence of a particular mid-level feature in an image of lesion in a patient based solely on the image.
摘要翻译：一种用于确定医学图像中恶性特征的存在或不存在的方法，其中由一个或多个图像读取专家检查由实际患者取得的各种类型的损伤的多个基础比较或训练图像以创建第一数据库阵列。使用一个或多个图像处理算法确定相同多个基本比较或训练图像中的每个病变的低级特征以获得第二数据库阵列集。组合第一和第二数据库阵列组以创建训练数据库阵列集合，其被输入到发现/学习从低级特征的子集映射到第一数据库阵列集合中的专家评估的分类器的学习系统。分类器用于仅基于图像来确定患者的病变图像中特定中级特征的存在。

3. 发明授权

US09251593B2 Medical imaging system and a method for segmenting an object of interest 有权
标题翻译：医学成像系统和分割感兴趣对象的方法
公开(公告)号：US09251593B2
公开(公告)日：2016-02-02
申请号：US10550344
申请日：2004-03-18
申请人： Nicolas Villain , Claude Cohen-Bacrie , Jean-Michel LaGrange , Claire Levrier , Robert Randall Entrekin
发明人： Nicolas Villain , Claude Cohen-Bacrie , Jean-Michel LaGrange , Claire Levrier , Robert Randall Entrekin
IPC分类号： A61B5/05 , G06T7/00
CPC分类号： G06T7/0081 , A61B2576/00 , G06F19/00 , G06T7/11 , G06T7/155 , G06T2207/10132 , G06T2207/20132 , G06T2207/20152 , G06T2207/30004
摘要： The invention concerns a medical imaging system comprising means (4) of segmenting a region of interest around an object of interest within a volume of 3D data (3DV). The system according to the invention comprises means (5) of calculating a sub-regions map (CSR) within the segmented region (RS) and correction means (6) intended to exclude sub-regions of the segmented region by means of said sub-regions map (CSR). The correction can be made automatically or manually by means of control means (7) enabling a user to select the sub-regions to be excluded. Display means (3) make it possible to display a 2D representation (2DR) of the volume of 3D data (3DV) and the segmented region (RS, RS′) at various stages of the processing.
摘要翻译：本发明涉及一种医学成像系统，其包括在3D数据量（3DV）的范围内分割感兴趣对象周围的感兴趣区域的装置（4）。根据本发明的系统包括计算分段区域（RS）内的子区域映射（CSR）的装置（5）和旨在通过所述子区域（RS）排除分段区域的子区域的校正装置（6）区域地图（CSR）。可以通过控制装置（7）自动或手动进行校正，使得用户能够选择要排除的子区域。显示装置（3）使得可以在处理的各个阶段显示3D数据量（3DV）和分割区域（RS，RS'）的2D表示（2DR）。

4. 发明授权

US08355547B2 Ultrasonic imaging apparatus with adaptable spatial image combination 有权
标题翻译：具有适应性空间图像组合的超声成像设备
公开(公告)号：US08355547B2
公开(公告)日：2013-01-15
申请号：US10525132
申请日：2003-08-05
申请人： Jean-Michel Lagrange , Claude Cohen-Bacrie , Claire Levrier , Nicolas Villain , Robert R. Entrekin
发明人： Jean-Michel Lagrange , Claude Cohen-Bacrie , Claire Levrier , Nicolas Villain , Robert R. Entrekin
IPC分类号： G06K9/00
CPC分类号： G01S15/8995 , G01S7/52077
摘要： An ultrasonic imaging apparatus using a method for combining CMB images of the same object including a step of seeking representative contours CNT of an interface on the images to be combined IM,[I], IM[J] is disclosed. The step is intended to define interest areas IA[I], IA[J] in the vicinity of the representative contours. The method also includes analyzing the interest areas IA[I], IA[J] being intended to allocate weights W[I], W[J] to the points on the interest areas IA[I], IA[J] and to the points corresponding to the interest areas IA[I], IA[J] on the various images. The method also includes constructing a combination image IMC, a point on the combination image IMC corresponding to a point on at least one interest area IA being obtained from a weighting of the corresponding points on the images to be combined IM[I], IM[J] according to the weights W[I], W[J] allocated in the analysis step ANA.
摘要翻译：公开了一种使用组合相同对象的CMB图像的方法的超声波成像装置，包括在待组合的图像IM，[I]，IM [J]上的接口的代表性轮廓CNT的步骤。该步骤旨在定义在代表性轮廓附近的兴趣区域IA [I]，IA [J]。该方法还包括分析兴趣区域IA [I]，IA [J]旨在将权重W [I]，W [J]分配给兴趣区域IA [I]，IA [J]上的点，以及对应于各个图像上的兴趣区域IA [I]，IA [J]的点。该方法还包括构成组合图像IMC，对应于要组合的图像上的对应点的加权获得的至少一个感兴趣区域IA上的点上的组合图像IMC上的点，IM [I]，IM [ J]根据在分析步骤ANA中分配的权重W [I]，W [J]。

5. 发明授权

US07361144B2 Ultrasound imaging system with a high lateral resolution 失效
标题翻译：具有高横向分辨率的超声成像系统
公开(公告)号：US07361144B2
公开(公告)日：2008-04-22
申请号：US10512492
申请日：2003-04-22
申请人： Claire Levrier , Claude Cohen-Bacrie , Nicholas Villain , Jean-Michel Lagrange , Robert R. Entrekin
发明人： Claire Levrier , Claude Cohen-Bacrie , Nicholas Villain , Jean-Michel Lagrange , Robert R. Entrekin
IPC分类号： A61B8/00
CPC分类号： G01S7/52049 , G01S15/8977 , G01S15/8995
摘要： The invention relates to an ultrasound imaging system for forming an echographic image of a medium, which system includes a set [REC] of transducer elements [EL] which are operative in a transmission mode and in a reception mode for ultrasound waves, construction means [REB] for constructing echographic signals on the basis of signals [S[1] . . . S[N]] received on the transducer elements [EL], display means [DIS] which are coupled to the construction means [REB] in order to display an image of the medium formed by means of the echographic signals. The construction means [REB] are such that in so-called exclusion zones, in which a coherent reflector is detected and which are determined by determination means [DET], the reception delays [D] are estimated in a manner [INT] other than that [CORR] used for the other zones. The calculation [CAL] of echographic signals is then carried out on the basis of the estimated delays [D[Z],Di[Z}}. The invention enables a correction of phase aberrations and nevertheless offers an excellent lateral resolution, notably in the case of point coherent reflectors.
摘要翻译：本发明涉及一种用于形成介质的回波图像的超声波成像系统，该系统包括以传输模式和超声波接收模式操作的换能器元件[EL]的组[REC]，构造装置[ REB]，用于根据信号[S [1]构建回波信号。。。 S [N]]接收到传感器元件[EL]上，显示装置[DIS]，它们耦合到构造装置[REB]，以便显示通过回波信号形成的介质的图像。构造装置[REB]使得在所谓的排除区域中，其中检测到相干反射器并且由确定装置[DET]确定，所述接收延迟[D]以除[ [CORR]用于其他区域。然后基于估计的延迟[D [Z]，Di [Z}}进行回波信号的计算[CAL]。本发明能够校正相位差，并且提供优异的横向分辨率，特别是在点相干反射器的情况下。

6. 发明申请

US20060173324A1 3d imaging system and method for signaling an object of interest in a volume of data 审中-公开
标题翻译： 3d成像系统和用于在一卷数据中发信号通知对象的方法
公开(公告)号：US20060173324A1
公开(公告)日：2006-08-03
申请号：US10545591
申请日：2004-03-01
申请人： Claude Cohen-Bacrie , Jean-Michel Lagrange , Nicolas Villain , Claire Levrier , Robert Entrekin
发明人： Claude Cohen-Bacrie , Jean-Michel Lagrange , Nicolas Villain , Claire Levrier , Robert Entrekin
IPC分类号： A61B8/14
CPC分类号： G06T19/00 , G06T7/0012 , G06T2207/30068 , G06T2210/41 , G06T2219/008 , G06T2219/028
摘要： The invention concerns a medical imaging system comprising means (2) of acquiring at least one volume of 3D data (3DV), means (3) of detecting at least one object of interest in said volume of data, display means (4) able to supply a 2D representation (2DR) of said volume of data and signaling means (5) intended to signal a location of said object of interest by means of a signal (SIG) superimposed on said 2D representation.
摘要翻译：本发明涉及一种医疗成像系统，其包括获取至少一个体积的3D数据（3 DV）的装置（2），在所述数据量中检测至少一个感兴趣对象的装置（3），能够以提供所述数据量和信令装置（5）的2D表示（2DR），用于通过叠加在所述2D表示上的信号（SIG）来发信号通知所述感兴趣对象的位置。

7. 发明申请

US20060270912A1 Medical imaging system and a method for segmenting an object of interest 有权
标题翻译：医学成像系统和分割感兴趣对象的方法
公开(公告)号：US20060270912A1
公开(公告)日：2006-11-30
申请号：US10550344
申请日：2004-03-18
申请人： Nicolas Villain , Claude Cohen-Bacrie , Jean-Michel LaGrange , Claire Levrier , Robert Entrekin
发明人： Nicolas Villain , Claude Cohen-Bacrie , Jean-Michel LaGrange , Claire Levrier , Robert Entrekin
IPC分类号： A61B19/00
CPC分类号： G06T7/0081 , A61B2576/00 , G06F19/00 , G06T7/11 , G06T7/155 , G06T2207/10132 , G06T2207/20132 , G06T2207/20152 , G06T2207/30004
摘要： The invention concerns a medical imaging system comprising means (4) of segmenting a region of interest around an object of interest within a volume of 3D data (3DV). The system according to the invention comprises means (5) of calculating a sub-regions map (CSR) within the segmented region (RS) and correction means (6) intended to exclude sub-regions of the segmented region by means of said sub-regions map (CSR). The correction can be made automatically or manually by means of control means (7) enabling a user to select the sub-regions to be excluded. Display means (3) make it possible to display a 2D representation (2DR) of the volume of 3D data (3DV) and the segmented region (RS, RS′) at various stages of the processing.
摘要翻译：本发明涉及一种医学成像系统，其包括在3D数据量（3 DV）内分割感兴趣对象周围的感兴趣对象区域的装置（4）。根据本发明的系统包括计算分段区域（RS）内的子区域映射（CSR）的装置（5）和旨在通过所述子区域（RS）排除分段区域的子区域的校正装置（6）区域地图（CSR）。可以通过控制装置（7）自动或手动进行校正，使得用户能够选择要排除的子区域。显示装置（3）使得可以在处理的各个阶段显示3D数据量（3 DV）和分割区域（RS，RS'）的2D表示（2 DR）。

8. 发明申请

US20050288580A1 Ultrasonic imaging apparatus with adaptable spatial image combination 有权
标题翻译：具有适应性空间图像组合的超声成像设备
公开(公告)号：US20050288580A1
公开(公告)日：2005-12-29
申请号：US10525132
申请日：2003-08-05
申请人： Jean-Michel Lagrange , Claude Cohen-Bacrie , Claire Levrier , Nicolas Villain , Robert Entrekin
发明人： Jean-Michel Lagrange , Claude Cohen-Bacrie , Claire Levrier , Nicolas Villain , Robert Entrekin
IPC分类号： A61B8/00 , G01S7/52 , G01S15/89 , G06T1/00 , G06T3/00
CPC分类号： G01S15/8995 , G01S7/52077
摘要： The invention relates to an ultrasonic imaging apparatus using a method for combining CMB images of the same object including a step of seeking representative contours CNT of an interface on the images to be combined IM[I], IM[J], said step being intended to define interest areas IA[I], IA[J] in the vicinity of said representative contours, a step ANA of analyzing the interest areas IA[I], IA[J], said analysis step ANA being intended to allocate weights W[I], W[J] to the points on said interest areas IA[I], A[J] and to the points corresponding to said interest areas IA[I], IA[J] on the various images, a step CC of constructing a combination image IMC, a point on the combination image IMC corresponding to a point on at least one interest area IA being obtained from a weighting of the corresponding points on the images to be combined IM[I], IM[J] according to the weights W[I], W[J] allocated in said analysis step ANA. The invention makes it possible to preserve the properties of certain areas of a particular image within a combination of images without for all that being detrimental to the advantages shown by the combination. Application: Ultirasonic imaging apparatus using a spatial combination of images.
摘要翻译：本发明涉及一种使用组合相同对象的CMB图像的方法的超声波成像设备，包括在要组合的图像IM [I]，IM [J]上寻找代表性轮廓CNT的界面的步骤的步骤在所述代表性轮廓附近定义兴趣区域IA [I]，IA [J]，分析兴趣区域IA [I]，IA [J]的步骤ANA，所述分析步骤ANA旨在分配权重W [ I]，W [J]到所述兴趣区域IA [I]，A [J]上的点以及对于各个图像上的所述兴趣区域IA [I]，IA [J]的点，步骤CC 构成组合图像IMC，对应于至少一个感兴趣区域IA上的点的组合图像IMC上的点，根据要组合的图像IM [I]，IM [J]上的对应点的加权获得在所述分析步骤ANA中分配的权重W [I]，W [J]。本发明使得可以在图像组合中保留特定图像的特定区域的特性，而不是对于组合所示的优点的所有方面都是有害的。应用：使用图像的空间组合的超声成像设备。

9. 发明申请

US20060058668A1 Ultrasound imaging system with a high lateral resolution 失效
标题翻译：具有高横向分辨率的超声成像系统
公开(公告)号：US20060058668A1
公开(公告)日：2006-03-16
申请号：US10512492
申请日：2003-04-22
申请人： Claire Levrier , Claude Cohen-Bacrie , Nicolas Villain , Jean-Michel Lagrange , Robert Entrekin
发明人： Claire Levrier , Claude Cohen-Bacrie , Nicolas Villain , Jean-Michel Lagrange , Robert Entrekin
IPC分类号： A61B8/06
CPC分类号： G01S7/52049 , G01S15/8977 , G01S15/8995
摘要： The invention relates to an ultrasound imaging system for forming an echographic image of a medium, which system includes a set [REC] of transducer elements [EL] which are operative in a transmission mode and in a reception mode for ultra-sound waves, construction means [REB] for constructing echographic signals on the basis of signals [S[1] . . . S[N]] received on said transducer elements [EL], display means [DIS] which are coupled to said construction means [REB] in order to display an image of the medium formed by means of the echographic signals. Said construction means [REB] are such that in so-called exclusion zones, in which a coherent reflector is detected and which are determined by determination means [DET], the reception delays [D] are estimated in a manner [INT] other than that [CORR] used for the other zones. The calculation [CAL] of echographic s is then carried out on the basis of said estimated delays [D[Z],Di[Z]]. The invention enables a correction of phase aberrations and nevertheless offers an excellent lateral resolution, notably in the case of point coherent reflectors.
摘要翻译：本发明涉及用于形成介质的回波图像的超声波成像系统，该系统包括以传输模式和超声波的接收模式操作的换能器元件[EL]的集合[REC] 意思是[REB]，用于根据信号[S [1]构建回波信号。。。 S [N]]，所述显示装置[DIS]被耦合到所述构造装置[REB]上，以便显示通过回波信号形成的介质的图像。所述构造装置[REB]使得在所谓的排除区域中，其中检测到相干反射器并且由确定装置[DET]确定，所述接收延迟[D]以除[ [CORR]用于其他区域。然后基于所述推定的延迟[D [Z]，Di [Z]]进行回波记录的计算[CAL]。本发明能够校正相位差，并且提供优异的横向分辨率，特别是在点相干反射器的情况下。

10. 发明授权

US10795007B2 Method and a device for imaging a visco-elastic medium 有权
公开(公告)号：US10795007B2
公开(公告)日：2020-10-06
申请号：US12294898
申请日：2007-03-22
申请人： Jérémy Bercoff , David Savery , Claude Cohen-Bacrie , Jacques Souquet
发明人： Jérémy Bercoff , David Savery , Claude Cohen-Bacrie , Jacques Souquet
IPC分类号： G01S7/52 , G01S15/89 , A61B8/08 , A61B5/00 , A61N7/00
摘要： The invention relates to a method and a device for imaging a visco-elastic medium (2). The method comprises an excitation step during which an internal mechanical stress is generated in an excitation zone [A] and an imaging step of acquiring signals during the movements generated by the mechanical stress in the visco-elastic medium (2) in response to the internal mechanical stress in an imaging zone [B] that includes the excitation zone [A]. According to the invention, the method further comprises a step of calculating a quantitative index [Cij] associated with the rheological properties of the visco-elastic medium (2) at at least one point [Bij] of the imaging zone situated at a given depth outside the excitation zone [A].

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