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1. 发明授权

US08852664B2 Neo-menthyl derivatives as flavor materials 有权
标题翻译：新薄荷醇衍生物作为香料
公开(公告)号：US08852664B2
公开(公告)日：2014-10-07
申请号：US12482210
申请日：2009-06-10
申请人： Jakob Peter Ley , Heiko Oertling , Michael Backes , Tobias Vössing
发明人： Jakob Peter Ley , Heiko Oertling , Michael Backes , Tobias Vössing
IPC分类号： A23L1/228 , A23L1/226 , C07C335/14 , A23L1/22 , C07C271/36 , C07C271/34 , C07C271/38 , C07C275/26
CPC分类号： A23L1/22091 , A23L27/20 , A23L27/2024 , A23L27/2028 , A23L27/88 , C07C271/34 , C07C271/36 , C07C271/38 , C07C275/26 , C07C335/14 , C07C2601/02 , C07C2601/08 , C07C2601/14
摘要： The present invention relates primarily to the use of particular ureas, thioureas, carbamates, thiocarbamates and guanidines based on the neomenthyl structure and corresponding mixtures with one another or with further compounds as flavor materials or flavor material mixtures for producing, imparting, modifying and/or enhancing savory flavor notes. the invention furthermore relates to particular compositions, preparations and semifinished products which comprise the said compounds, as well as methods for producing, imparting, modifying and/or enhancing particular flavor impressions. Lastly, the invention also relates to the compounds themselves and to corresponding mixtures.
摘要翻译：本发明主要涉及基于新薄荷结构和相应混合物的特定脲，硫脲，氨基甲酸酯，硫代氨基甲酸酯和胍，或其它化合物作为调味料或调味料混合物用于生产，赋予，改性和/或增强美味香味。本发明还涉及包含所述化合物的特定组合物，制剂和半成品，以及用于生产，赋予，改性和/或增强特定风味印象的方法。最后，本发明还涉及化合物本身和相应的混合物。

2. 发明申请

US20090311401A1 Neo-Menthyl Derivatives as Flavor Materials 有权
标题翻译：新薄荷衍生物作为香料
公开(公告)号：US20090311401A1
公开(公告)日：2009-12-17
申请号：US12482210
申请日：2009-06-10
申请人： Jakob Peter Ley , Heiko Oertling , Michael Backes , Tobias Vossing
发明人： Jakob Peter Ley , Heiko Oertling , Michael Backes , Tobias Vossing
IPC分类号： A23L1/228
CPC分类号： A23L1/22091 , A23L27/20 , A23L27/2024 , A23L27/2028 , A23L27/88 , C07C271/34 , C07C271/36 , C07C271/38 , C07C275/26 , C07C335/14 , C07C2601/02 , C07C2601/08 , C07C2601/14
摘要： The present invention relates primarily to the use of particular ureas, thioureas, carbamates, thiocarbamates and guanidines based on the neomenthyl structure and corresponding mixtures with one another or with further compounds as flavor materials or flavor material mixtures for producing, imparting, modifying and/or enhancing savory flavor notes. the invention furthermore relates to particular compositions, preparations and semifinished products which comprise the said compounds, as well as methods for producing, imparting, modifying and/or enhancing particular flavor impressions. Lastly, the invention also relates to the compounds themselves and to corresponding mixtures.
摘要翻译：本发明主要涉及基于新薄荷结构和相应混合物的特定脲，硫脲，氨基甲酸酯，硫代氨基甲酸酯和胍，或其它化合物作为调味料或调味料混合物用于生产，赋予，改性和/或增强美味香味。本发明还涉及包含所述化合物的特定组合物，制剂和半成品，以及用于生产，赋予，改性和/或增强特定风味印象的方法。最后，本发明还涉及化合物本身和相应的混合物。

3. 发明授权

US08344025B2 Oxalic acid derivatives and use thereof as physiological cooling active ingredients 有权
标题翻译：草酸衍生物及其作为生理冷却活性成分的用途
公开(公告)号：US08344025B2
公开(公告)日：2013-01-01
申请号：US12193375
申请日：2008-08-18
申请人： Horst Surburg , Jan Looft , Heiko Oertling , Tobias Vössing
发明人： Horst Surburg , Jan Looft , Heiko Oertling , Tobias Vössing
IPC分类号： A61K31/215 , C07C69/608 , A61P11/00
CPC分类号： A61K8/42 , A23G3/36 , A23G4/06 , A61K8/49 , A61K2800/244 , A61Q11/00 , C07C233/56 , C07C2601/02 , C07C2601/14 , C07C2602/42 , C07D295/185
摘要： The present invention relates to specific oxalic acid derivatives and to corresponding mixtures and to uses thereof as physiological cooling active ingredients.
摘要翻译：本发明涉及具体的草酸衍生物和相应的混合物及其作为生理冷却活性成分的用途。

4. 发明申请

US20120263659A1 USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS 有权
标题翻译：使用生理冷却活性成分，以及含有此类活性成分的试剂
公开(公告)号：US20120263659A1
公开(公告)日：2012-10-18
申请号：US13510454
申请日：2010-11-22
申请人： Thomas Subkowski , Michael Backes , Heiko Oertling , Arnold Machinek , Hubert Loges , Ulrike Simchen , Horst Surburg , Claus Bollschweiler , Jens Wittenberg , Wolfgang Siegel
发明人： Thomas Subkowski , Michael Backes , Heiko Oertling , Arnold Machinek , Hubert Loges , Ulrike Simchen , Horst Surburg , Claus Bollschweiler , Jens Wittenberg , Wolfgang Siegel
IPC分类号： A61K31/438 , C07D491/048 , A61K31/4745 , C07D401/04 , A61K31/506 , C07D413/14 , A61K31/5377 , C07D405/12 , A61K31/443 , C07D317/60 , A61K31/36 , C07C233/11 , A61K31/165 , C07D213/74 , A61K31/4402 , C07D277/42 , A61K31/426 , A61Q11/00 , A61P11/14 , A61P11/04 , C12N5/07 , C07D495/10
CPC分类号： C07D495/20 , A23G3/36 , A23G4/06 , A23L2/52 , A23L27/2054 , A23L33/10 , A23V2002/00 , A24B13/00 , A24D1/002 , A61K8/49 , A61K8/4953 , A61K31/165 , A61K31/167 , A61K31/36 , A61K31/426 , A61K31/4375 , A61K31/438 , A61K31/4402 , A61K31/443 , A61K31/4741 , A61K31/4743 , A61K31/506 , A61K31/513 , A61K31/5377 , A61K2800/10 , A61K2800/244 , A61K2800/78 , A61Q11/00 , A61Q17/04 , A61Q19/00 , A61Q19/004 , C07C233/11 , C07C235/36 , C07C235/38 , C07C2601/14 , C07D213/75 , C07D317/60 , C07D401/04 , C07D405/12 , C07D491/147 , C07D495/22 , C09D5/1625 , D06M15/03 , D06M15/07 , D06M16/00
摘要： The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.
摘要翻译：本发明涉及一种用于实现对皮肤或粘膜的冷却作用的TRPM8调节剂。

5. 发明授权

US08927605B2 Use of physiological cooling active ingredients, and agents containing such active ingredients 有权
标题翻译：使用生理冷却活性成分，以及含有这些活性成分的药剂
公开(公告)号：US08927605B2
公开(公告)日：2015-01-06
申请号：US13510454
申请日：2010-11-22
申请人： Thomas Subkowski , Michael Backes , Heiko Oertling , Arnold Machinek , Hubert Loges , Ulrike Simchen , Horst Surburg , Claus Bollschweiler , Jens Wittenberg , Wolfgang Siegel
发明人： Thomas Subkowski , Michael Backes , Heiko Oertling , Arnold Machinek , Hubert Loges , Ulrike Simchen , Horst Surburg , Claus Bollschweiler , Jens Wittenberg , Wolfgang Siegel
IPC分类号： A61K31/165 , A61K31/4743 , A61K31/167 , D06M15/03 , C07D405/12 , C07C235/38 , D06M15/07 , A61K31/506 , C07D317/60 , A23G4/06 , D06M16/00 , A61Q19/00 , A61K31/426 , A61K31/513 , A23L2/52 , C07D213/75 , A61K31/4741 , A23L1/226 , A61K31/443 , A61K8/49 , A61K31/4402 , C09D5/16 , C07C235/36 , C07D401/04 , A23L1/30 , A23G3/36 , C07D495/20 , C07C233/11 , C07D495/22 , A61K31/36 , A61Q17/04 , A61Q11/00
CPC分类号： C07D495/20 , A23G3/36 , A23G4/06 , A23L2/52 , A23L27/2054 , A23L33/10 , A23V2002/00 , A24B13/00 , A24D1/002 , A61K8/49 , A61K8/4953 , A61K31/165 , A61K31/167 , A61K31/36 , A61K31/426 , A61K31/4375 , A61K31/438 , A61K31/4402 , A61K31/443 , A61K31/4741 , A61K31/4743 , A61K31/506 , A61K31/513 , A61K31/5377 , A61K2800/10 , A61K2800/244 , A61K2800/78 , A61Q11/00 , A61Q17/04 , A61Q19/00 , A61Q19/004 , C07C233/11 , C07C235/36 , C07C235/38 , C07C2601/14 , C07D213/75 , C07D317/60 , C07D401/04 , C07D405/12 , C07D491/147 , C07D495/22 , C09D5/1625 , D06M15/03 , D06M15/07 , D06M16/00
摘要： The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.
摘要翻译：本发明涉及一种用于实现对皮肤或粘膜的冷却作用的TRPM8调节剂。

6. 发明申请

US20130137710A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS 有权
标题翻译： CYCLOHEXYL碳酸酯化合物作为活性抗细胞成分
公开(公告)号：US20130137710A1
公开(公告)日：2013-05-30
申请号：US13699487
申请日：2010-05-25
申请人： Imke Meyer , Heiko Oertling , Nadine Hillebrand , Claudia Gömann , Rahim Brodhage
发明人： Imke Meyer , Heiko Oertling , Nadine Hillebrand , Claudia Gömann , Rahim Brodhage
IPC分类号： A61K8/44 , A61K31/27 , A61Q19/06
CPC分类号： A61K8/44 , A61K31/00 , A61K31/27 , A61Q19/06
摘要： The present invention relates to the cosmetic, dermatological or therapeutic use of certain cyclohexyl carbamate compounds of formula (I) given below, preferably as anti-cellulite actives. The invention further relates to compositions and cosmetic, dermatological or therapeutic products comprising such compounds of formula (I), which are preferably suitable for the prophylaxis (prevention) and cosmetic treatment (combating) of cellulite in human beings, corresponding methods and novel compounds of formula (I) wherein A denotes wherein X, Y and Z independently of one another denote hydrogen, C1-C4-alkyl or C2-C4-alkenyl, wherein optionally two of the radicals X, Y and Z are covalently bonded to one another under formation of a bicyclic ring system, in such a bicyclic ring system two of the radicals X, Y and Z together preferably form a radical having 1 to 4 carbon atoms, preferably a hydrocarbon radical having 1 to 3 carbon atoms, B denotes NR1R2, wherein R1 denotes hydrogen or an organic radical having 1 to 14 carbon atoms, R2 denotes an organic radical having 1 to 14 carbon atoms, and wherein optionally R1 and R2 are covalently bonded to one another, preferably so that B is a 3 to 8 membered ring.
摘要翻译：本发明涉及以下给出的某些式（I）环己基氨基甲酸酯化合物的化妆品，皮肤病学或治疗用途，优选作为抗脂肪团活性物质。本发明还涉及包含这样的式（I）化合物的组合物和化妆品，皮肤病学或治疗产品，其优选适用于预防（预防）和化妆品处理（抗击）人体中的脂肪团，相应的方法和新的化合物式（I）其中A表示其中X，Y和Z彼此独立地表示氢，C 1 -C 4 - 烷基或C 2 -C 4 - 烯基，其中任选地，基团X，Y和Z中的两个彼此共价键合双环体系的形成在这样的双环体系中，基团X，Y和Z中的两个一起优选形成具有1至4个碳原子的基团，优选地具有1至3个碳原子的烃基，B表示NR1R2，其中 R1表示氢或具有1至14个碳原子的有机基团，R2表示具有1至14个碳原子的有机基团，并且其中任选地R 1和R 2彼此共价键合，优选使得 B是3至8元环。

7. 发明申请

US20100130624A1 4-ALKYL SUBSTITUTED PYRIDINES AS ODIFEROUS SUBSTANCES 有权
标题翻译： 4-ALKYL取代的吡啶作为无害物质
公开(公告)号：US20100130624A1
公开(公告)日：2010-05-27
申请号：US12622996
申请日：2009-11-20
申请人： Heiko Oertling
发明人： Heiko Oertling
IPC分类号： A61K8/49 , A61K8/00 , C11D3/50 , A61Q13/00
CPC分类号： C11D3/28 , C11B9/0092 , C11D3/50 , C11D9/442
摘要： The present invention primarily concerns certain 4-alkyl pyridines of the following formula (I), wherein R is C8-C12 alkyl, odiferous substance mixtures and aromatic substance mixtures containing these 4-alkyl pyridines, the respective uses thereof as an odiferous or aromatic substance (mixture) and corresponding perfumed products.
摘要翻译：本发明主要涉及下列通式（I）的某些4-烷基吡啶，其中R是C 8 -C 12烷基，含磷物质混合物和含有这些4-烷基吡啶的芳香族物质混合物，其各自的用途作为含量或芳族物质（混合物）和相应的香料产品。

8. 发明申请

US20090054520A1 OXALIC ACID DERIVATIVES AND USE THEREOF AS PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS 有权
标题翻译：氧化酸衍生物及其作为生理冷却活性成分的用途
公开(公告)号：US20090054520A1
公开(公告)日：2009-02-26
申请号：US12193375
申请日：2008-08-18
申请人： Horst Surburg , Jan Looft , Heiko Oertling , Tobias Vossing
发明人： Horst Surburg , Jan Looft , Heiko Oertling , Tobias Vossing
IPC分类号： A61K31/215 , C07C69/608 , A61P11/00
CPC分类号： A61K8/42 , A23G3/36 , A23G4/06 , A61K8/49 , A61K2800/244 , A61Q11/00 , C07C233/56 , C07C2601/02 , C07C2601/14 , C07C2602/42 , C07D295/185
摘要： The present invention relates to specific oxalic acid derivatives and to corresponding mixtures and to uses thereof as physiological cooling active ingredients.
摘要翻译：本发明涉及具体的草酸衍生物和相应的混合物及其作为生理冷却活性成分的用途。

9. 发明申请

US20110081303A1 TEETH CLEANING COMPOUND CONTAINING MENTHOL WITH REDUCED BITTER SENSATION 有权
标题翻译：含有减少双点传感器的含有清洁剂的清洁清洁剂
公开(公告)号：US20110081303A1
公开(公告)日：2011-04-07
申请号：US12898893
申请日：2010-10-06
申请人： Heiko Oertling , Hubert Loges , Arnold Machinek , Ulrike Simchen , Horst Surburg
发明人： Heiko Oertling , Hubert Loges , Arnold Machinek , Ulrike Simchen , Horst Surburg
IPC分类号： A61K8/42 , A61Q11/00
CPC分类号： A61Q11/00 , A61K8/0216 , A61K8/0241 , A61K8/11 , A61K8/347 , A61K8/35 , A61K8/36 , A61K2800/244
摘要： The present invention primarily concerns teeth cleaning compounds containing menthol for use with a toothbrush, preferably tooth pastes, tooth crèmes, tooth cleaning gels or tooth powders. Such a tooth cleaning compound according to the invention contains menthol and a quantity, for masking the bitterness of the menthol, of menthane carboxylic acid-N-(4-methoxyphenyl)-amide (WS-12) of the following formula (Ia), in particular of the following formula (Ib), i.e. L-menthane carboxylic acid-N-(4-methoxyphenyl)-amide. The present invention also concerns the use of menthane carboxylic acid-N-(4-methoxyphenyl)-amide (WS-12) of the formulas (Ia) or (preferably) (Ib) to mask the bitter taste of menthol in a teeth cleaning compound.The present invention also concerns a method for dissolving menthane carboxylic acid-N-(4-methoxyphenyl)-amide (WS-12) in a teeth cleaning compound and a method for masking the bitterness of menthol in a teeth cleaning compound.
摘要翻译：本发明主要涉及含有用于牙刷，优选牙膏，牙膏，牙齿清洁凝胶或牙粉的薄荷醇的牙齿清洁化合物。根据本发明的这种牙齿清洁化合物含有薄荷醇和用于掩蔽薄荷醇的苦味的量的下式（Ia）的薄荷烷羧酸-N-（4-甲氧基苯基） - 酰胺（WS-12）特别是下式（Ib），即L-薄荷烷羧酸-N-（4-甲氧基苯基） - 酰胺。本发明还涉及式（Ia）或（优选）（Ib）的薄荷烷羧酸-N-（4-甲氧基苯基） - 酰胺（WS-12）在牙齿清洁中掩蔽薄荷醇的苦味的用途复合。本发明还涉及将薄荷烷羧酸-N-（4-甲氧基苯基） - 酰胺（WS-12）溶解在牙齿清洁化合物中的方法和用于掩蔽牙齿清洁化合物中薄荷醇的苦味的方法。

10. 发明授权

US07846886B2 Mixtures of unsaturated macrocyclic epoxides as odoriferous substances 有权
标题翻译：不饱和大环环氧化物作为气味物质的混合物
公开(公告)号：US07846886B2
公开(公告)日：2010-12-07
申请号：US12223633
申请日：2007-01-10
申请人： Heiko Oertling , Horst Surburg
发明人： Heiko Oertling , Horst Surburg
IPC分类号： C11D3/50
CPC分类号： C07D303/06
摘要： A mixture of 17-oxabicyclo[14.1.0]heptadec-8-ene and its isomers as an odoriferous substance and an odoriferous or aroma substance mixture comprising 17-oxabicyclo[14.1.0]heptadec-8-ene and one or more further odoriferous or aroma substances are described.
摘要翻译： 17-氧杂二环[14.1.0]十七碳-8-烯及其异构体作为有气味物质和含有气味或芳香物质混合物的混合物，其包含17-氧杂二环[14.1.0]十七碳-8-烯和一种或多种另外的有气味或芳香物质。

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