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1. 发明申请

US20100062030A1 USE OF DIACETYL DIMER AS AN AROMATIC AND/OR FLAVOURING SUBSTANCE 失效
标题翻译：使用二乙二醇作为芳香和/或挥发性物质
公开(公告)号：US20100062030A1
公开(公告)日：2010-03-11
申请号：US12300820
申请日：2007-05-07
申请人： Jakob Ley , Berthold Weber , Gerhard Krammer , Ingo Reiss , Heinz-Jürgen Bertram , Ian Galfield , Petra Hoffmann-Lücke
发明人： Jakob Ley , Berthold Weber , Gerhard Krammer , Ingo Reiss , Heinz-Jürgen Bertram , Ian Galfield , Petra Hoffmann-Lücke
IPC分类号： A23L1/226 , A61K8/49 , A61K8/02 , A61Q11/00
CPC分类号： A23C9/1307 , A21D2/14 , A21D13/40 , A21D13/80 , A23C9/156 , A23D7/0056 , A23D7/015 , A23G3/36 , A23G4/06 , A23G9/32 , A23L19/00 , A23L27/206 , C12C5/026 , C12G1/00 , C12G3/06
摘要： The invention relates to the use of 5-acetyl-2,5-dimethyl-2-hydroxy-tetrahydrofuran-3-one (diacetyl dimer of formula (I)) in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two, three or four of its stereoisomers (i) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (ii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavour; and/or (iii) as an aromatic and/or flavouring substance. The invention furthermore relates to a process (i) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (ii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavour, to corresponding aromatic compositions, to formulations selected from a nutrition formulation (foodstuff), an oral hygiene formulation, a luxury product formulation, a formulation for oral pharmaceutical use or a semi-finished good formulation for the preparation of nutrition formulations or luxury product formulations, as well as preparations comprising one or more of said compositions and/or formulations.
摘要翻译：本发明涉及其一种立体异构体形式的5-乙酰基-2,5-二甲基-2-羟基 - 四氢呋喃-3-酮（式（I）的二乙酰二聚体）或混合物形式的用途包含或含有二，三或四种立体异构体（i）用于赋予，增强和/或改变口腔中的乳状和/或脂肪感觉，（ii）用于赋予，增强和/或改变甜味，奶油状和/或奶油味; 和/或（iii）作为芳香和/或调味物质。本发明还涉及一种用于赋予，增强和/或改变口腔中的乳状和/或脂肪感觉的方法（i），（ii）用于赋予，加强和/或改变甜味，奶油状和/ 或奶油味，与相应的芳香族组合物相对于选自营养制剂（食品），口腔卫生制剂，豪华产品制剂，用于口服药物用途的制剂或用于制备营养制剂的半成品良好制剂的制剂，或豪华产品制剂，以及包含一种或多种所述组合物和/或制剂的制剂。

2. 发明授权

US08287934B2 Use of diacetyl dimer as an aromatic and/or flavouring substance 失效
标题翻译：使用二乙酰二聚体作为芳香和/或调味物质
公开(公告)号：US08287934B2
公开(公告)日：2012-10-16
申请号：US12300820
申请日：2007-05-07
申请人： Jakob Ley , Berthold Weber , Gerhard Krammer , Ingo Reiss , Heinz-Jürgen Bertram , Ian Gatfield , Petra Hoffmann-Lücke
发明人： Jakob Ley , Berthold Weber , Gerhard Krammer , Ingo Reiss , Heinz-Jürgen Bertram , Ian Gatfield , Petra Hoffmann-Lücke
IPC分类号： A23L1/22 , A61K8/02
CPC分类号： A23C9/1307 , A21D2/14 , A21D13/40 , A21D13/80 , A23C9/156 , A23D7/0056 , A23D7/015 , A23G3/36 , A23G4/06 , A23G9/32 , A23L19/00 , A23L27/206 , C12C5/026 , C12G1/00 , C12G3/06
摘要： The invention relates to the use of 5-acetyl-2,5-dimethyl-2-hydroxy-tetrahydrofuran-3-one (diacetyl dimer of formula (I)) in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two, three or four of its stereoisomers (i) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (ii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavor; and/or (iii) as an aromatic and/or flavoring substance. The invention furthermore relates to a process (i) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (ii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavor, to corresponding aromatic compositions, to formulations selected from a nutrition formulation (foodstuff), an oral hygiene formulation, a luxury product formulation, a formulation for oral pharmaceutical use or a semi-finished good formulation for the preparation of nutrition formulations or luxury product formulations, as well as preparations comprising one or more of said compositions and/or formulations.
摘要翻译：本发明涉及其一种立体异构体形式的5-乙酰基-2,5-二甲基-2-羟基 - 四氢呋喃-3-酮（式（I）的二乙酰二聚体）或混合物形式的用途包含或含有二，三或四种立体异构体（i）用于赋予，增强和/或改变口腔中的乳状和/或脂肪感觉，（ii）用于赋予，增强和/或改变甜味，奶油状和/或奶油味; 和/或（iii）作为芳香和/或调味物质。本发明还涉及一种用于赋予，增强和/或改变口腔中的乳状和/或脂肪感觉的方法（i），（ii）用于赋予，加强和/或改变甜味，奶油状和/ 或奶油味，与相应的芳香族组合物相对于选自营养制剂（食品），口腔卫生制剂，豪华产品制剂，用于口服药物用途的制剂或用于制备营养制剂的半成品良好制剂的制剂，或豪华产品制剂，以及包含一种或多种所述组合物和/或制剂的制剂。

3. 发明授权

US08318711B2 Use of diacetyl trimer as an aromatic and flavouring substance 有权
标题翻译：使用二乙酰三聚体作为芳香和调味物质
公开(公告)号：US08318711B2
公开(公告)日：2012-11-27
申请号：US11720582
申请日：2005-11-30
申请人： Ian Gatfield , Jakob Ley , Ingo Reiss , Günter Kindel , Gerhard Krammer
发明人： Ian Gatfield , Jakob Ley , Ingo Reiss , Günter Kindel , Gerhard Krammer
IPC分类号： A01N43/00 , A01N35/00 , A61K31/33 , A61K31/12
CPC分类号： A23L27/88 , A23L27/86
摘要： The invention relates to the use of 2,5-diacetyl-3a,5,6,6a-tetrahydro-6a-hydroxy-2,3a,5-trimethylfuro[2,3-d]-1,3-dioxole (diacetyl trimer) of the formula in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two or more of the stereoisomers (i) as an odoriferous or aromatic substance, (ii) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (iii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavor, and/or (iv) for masking a bitter flavor. The invention furthermore relates to corresponding aromatic compositions as well as compositions which serve for nutrition, oral hygiene, consumption for pleasure or for oral pharmaceutical use.
摘要翻译：本发明涉及2,5-二乙酰基-3,3,5,6,6a-四氢-6a-羟基-2,3a，5-三甲基呋喃并[2,3-d] -1,3-二氧杂环戊烯（二乙酰基三聚体）式中其一种立体异构体形式或以由两种或多种立体异构体组成的混合物形式的混合物（i）作为有气味或芳族物质，（ii）用于赋予，增强和/或改变（iii）用于赋予，加强和/或改变甜的，黄油状，奶油状和/或奶油味，和/或（iv）掩蔽苦味的口香糖和/或脂肪感觉。本发明还涉及相应的芳族组合物以及用于营养，口腔卫生，快乐消费或口服药物使用的组合物。

4. 发明申请

US20090208426A1 Use of Diacetyl Trimer as an Aromatic and Flavouring Substance 有权
标题翻译：使用二乙酰三聚体作为芳香和调味物质
公开(公告)号：US20090208426A1
公开(公告)日：2009-08-20
申请号：US11720582
申请日：2005-11-30
申请人： Ian Gatfield , Jakob Ley , Ingo Reiss , Günter Kindel , Gerhard Krammer
发明人： Ian Gatfield , Jakob Ley , Ingo Reiss , Günter Kindel , Gerhard Krammer
IPC分类号： A61K8/49 , C07D317/44 , A23L1/226 , A61K31/357 , A61Q11/00
CPC分类号： A23L27/88 , A23L27/86
摘要： The invention relates to the use of 2,5-diacetyl-3a,5,6,6a-tetrahydro-6a-hydroxy-2,3a,5-trimethylfuro[2,3-d]-1,3-dioxole (diacetyl trimer) of the formula in the form of one of its stereoisomers or in the form of a mixture consisting of or containing two or more of the stereoisomers (i) as an odoriferous or aromatic substance, (ii) for imparting, intensifying and/or modifying a creamy and/or fatty sensation in the mouth, (iii) for imparting, intensifying and/or modifying a sweet, buttery, cream-like and/or creamy flavour, and/or (iv) for masking a bitter flavour. The invention furthermore relates to corresponding aromatic compositions as well as compositions which serve for nutrition, oral hygiene, consumption for pleasure or for oral pharmaceutical use.
摘要翻译：本发明涉及2,5-二乙酰基-3,3,5,6,6a-四氢-6a-羟基-2,3a，5-三甲基呋喃并[2,3-d] -1,3-二氧杂环戊烯（二乙酰基三聚体）式中其一种立体异构体形式或以由两种或多种立体异构体组成的混合物形式的混合物（i）作为有气味或芳族物质，（ii）用于赋予，增强和/或改变（iii）用于赋予，加强和/或改变甜的，黄油状，奶油状和/或奶油味，和/或（iv）掩蔽苦味的口香糖和/或脂肪感觉。本发明还涉及相应的芳族组合物以及用于营养，口腔卫生，快乐消费或口服药物使用的组合物。

5. 发明授权

US08828469B2 Use of alkamides for masking an unpleasant flavor 有权
标题翻译：使用烷酰胺掩蔽不愉快的味道
公开(公告)号：US08828469B2
公开(公告)日：2014-09-09
申请号：US12266209
申请日：2008-11-06
申请人： Kathrin Langer , Jakob Ley , Gerald Reinders , Günter Kindel , Gerhard Krammer
发明人： Kathrin Langer , Jakob Ley , Gerald Reinders , Günter Kindel , Gerhard Krammer
IPC分类号： A23L1/22 , A23L2/56 , A61K8/18 , A61Q13/00 , A23G9/32 , A23G1/32 , A21D2/24 , A23C9/13 , A23C11/10
CPC分类号： A23L1/22075 , A21D2/24 , A23C9/1307 , A23C11/103 , A23G1/32 , A23G9/32 , A23L27/84 , A23L27/86
摘要： An individual alkamide and/or a mixture having two or more different alkamides, is disclosed for changing, masking or reducing the unpleasant flavor impression of an unpleasant-tasting substance or mixture of substances. The alkamide can be trans-pellitorine; cis-pellitorine; 2Z,4Z- or 2Z,4E-decadienoic acid-N-isobutylamide; 2E,4E-decadienoic acid-N-([2S]-2-methylbutyl)amide; 2E,4E-decadienoic acid-N-([2R]-2-methylbutylamide); 2E,4Z-decadienoic acid-N-(2-methylbutyl)amide; achilleamide; sarmentine; 2E- or 3E-decenoic acid-N-isobutylamide; 3E-nonenoic acid-N-isobutylamide; spilanthol; homospilanthol; 2E,6Z,8E-decatrienoic acid-N-([2R]-2-methylbutyl)amide; 2E- or 2Z-decen-4-oic acid-N-isobutylamide; α-sanshool; α-hydroxysanshool; γ-hydroxysanshool; γ-hydroxysanshool; γ-hydroxyisosanshool; γ-dehydrosanshool; γ-sanshool; bungeanool; isobungeanool; dihydrobungeanool; or tetrahydrobungeanool, or combinations thereof.
摘要翻译：公开了具有两种或更多种不同的烷酰胺的单独的烷酰胺和/或混合物，用于改变，掩蔽或减少不愉快的味道物质或物质混合物的不愉快的风味印象。烷酰胺可以是反式蝶呤; 顺式丝氨酸 2Z，4Z-或2Z，4E-癸二烯酸-N-异丁酰胺; 2E，4E-癸二烯酸-N - （[2S] -2-甲基丁基）酰胺; 2E，4E-癸二烯酸-N - （[2R] -2-甲基丁酰胺）; 2E，4Z-癸二烯酸-N-（2-甲基丁基）酰胺; 甲酰胺 sarmentine; 2E-或3E-癸烯酸-N-异丁酰胺; 3E-壬烯酸-N-异丁酰胺; 皮兰替康同型六醇 2E，6Z，8E-十二碳烯酸-N - （[2R] -2-甲基丁基）酰胺; 2E-或2Z-癸-4-酸酸-N-异丁酰胺; α-sans学校 α-羟基蛋白 γ-羟基辛酸 γ-羟基辛酸 γ-羟基异黄酮 γ-脱水师 γ-sans学校皮卡诺异丁腈二氢胆碱; 或四氢胆甾醇，或其组合。

6. 发明授权

US10251409B2 Mixtures of matter 有权
公开(公告)号：US10251409B2
公开(公告)日：2019-04-09
申请号：US15032843
申请日：2014-10-26
申请人： Uwe Schafer , Gerhard Krammer , Gerald Glaubitz , Thomas Riess , Jakob Ley , Susanne Paetz
发明人： Uwe Schafer , Gerhard Krammer , Gerald Glaubitz , Thomas Riess , Jakob Ley , Susanne Paetz
IPC分类号： A23G4/00 , A23G4/10 , A23C9/13 , A23C9/154 , A23L2/60 , A23G3/36 , A23G4/06 , A61Q11/00 , A61K8/60 , A61K8/73 , A23L9/10 , A23L27/00 , A23L27/20 , A23L27/30 , A23G3/42 , A23L1/187 , A23L1/22 , A23L1/226 , A23L1/236
摘要： Suggested is a mixture of matter, comprising: (a) steviol glycosides, (b) starch degradation products and (c) one or more phenolic sweetness-enhancing aroma substances selected from the group formed by hesperetin, phloretin, 1-(2,4-dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)propan-1-one, 7,3-dihydroxy-4′-methoxyflavan and 5-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-7-methoxy-2-chromanone. On condition that components (a+b) and (c) are present in a ratio by weight of from 1.99 to 99:1.

7. 发明申请

US20100331349A1 Use of gamma-aminobutyric acid to mask or reduce an unpleasant flavour impression and preparations containing gamma-aminobutyric 审中-公开
标题翻译：使用γ-氨基丁酸掩盖或减少令人不快的风味印象和含有γ-氨基丁酸的制剂
公开(公告)号：US20100331349A1
公开(公告)日：2010-12-30
申请号：US10599701
申请日：2005-03-29
申请人： Jakob Ley , Gunter Kindel , Gerhard Krammer , Thomas Hofmann , Nina Rotzoll
发明人： Jakob Ley , Gunter Kindel , Gerhard Krammer , Thomas Hofmann , Nina Rotzoll
IPC分类号： A61K31/522 , A61K31/439 , A61P43/00 , A23L1/227 , A23L2/56
CPC分类号： A61Q11/00 , A23L27/82 , A23L27/84 , A23L27/86 , A23V2002/00 , A61K8/44 , A23V2200/16 , A23V2250/038
摘要： The use of γ-aminobutyric acid or a physiologically acceptable salt of γ-aminobutyric acid to mask or reduce the unpleasant flavour impression of an unpleasantly tasting substance is described. The food, beverage or oral care preparations or oral pharmaceutical preparations comprising at least one unpleasantly tasting substance and γ-aminobutyric acid are also described.
摘要翻译：描述了使用γ-氨基丁酸或γ-氨基丁酸的生理学上可接受的盐来掩蔽或减少令人不愉快的味道物质的令人不快的风味印象。还描述了包含至少一种不愉快的品尝物质和γ-氨基丁酸的食品，饮料或口腔护理制剂或口服药物制剂。

8. 发明申请

US20080227867A1 USE OF 4-HYDROXYCHALCONE DERIVATIVES FOR MASKING AN UPLEASANT TASTE 有权
标题翻译：使用4-羟基喹啉衍生物，用于吸收有毒物质
公开(公告)号：US20080227867A1
公开(公告)日：2008-09-18
申请号：US12046978
申请日：2008-03-12
申请人： Jakob Ley , Susanne Paetz , Thomas Riess , Gerhard Krammer
发明人： Jakob Ley , Susanne Paetz , Thomas Riess , Gerhard Krammer
IPC分类号： A61K31/12
CPC分类号： C07C49/83 , A23L27/84 , A23L27/86 , A23V2002/00 , C07C49/835 , C07C49/84 , A23V2200/16 , A23V2250/25
摘要： The use is described of the 4-hydroxychalcone derivatives of the formula (I) wherein A may represent a single or double bond, R1, R2 and R3, mutually independently, may in each case mean H, OH or (preferably C1-C4) alkoxy, providing that at least one of the residues R1 to R3 means OH, and R4 means H, OH or (preferably C1-C4) alkoxy, and/or (ii) the salts thereof and (iii) mixtures thereof to mask or reduce the unpleasant taste impression of an unpleasant tasting substance, as are corresponding methods and preparations.
摘要翻译：描述了式（I）的4-羟基查耳酮衍生物的用途，其中A可以表示单键或双键，R 1，R 2，R 2，在相互独立的情况下，在每种情况下可以是指H，OH或（优选C 1 -C 4 -C 4）烷氧基，条件是至少一个残基 R 1至R 3表示OH，R 4表示H，OH或（优选C 1 -C 3烷基）和/或（ii）其盐和（iii）它们的混合物，以掩盖或减少不愉快的品尝物质的令人不快的味觉，如相应的方法和制剂。

9. 发明申请

US20050234132A1 Production of cis-pellitorin and use as a flavouring 失效
标题翻译：生产顺式丝氨酸蛋白并用作调味剂
公开(公告)号：US20050234132A1
公开(公告)日：2005-10-20
申请号：US10518074
申请日：2003-06-20
申请人： Ian-Lucas Gatfield , Jakob Ley , Jan Foerstner , Gerhard Krammer , Arnold Machinek
发明人： Ian-Lucas Gatfield , Jakob Ley , Jan Foerstner , Gerhard Krammer , Arnold Machinek
IPC分类号： A23L27/20 , A61K8/42 , A61Q11/00 , C07C231/02 , C07C233/09 , C11B9/00 , A61K31/16
CPC分类号： A61Q11/00 , A23G4/06 , A23L27/202 , A61K8/42 , C07C231/02 , C11B9/0007 , C07C233/09
摘要： The invention describes a process for the production of 2E,4Z-decadienoic acid-N-isobutylamide (cis-pellitorine) and its use as a pungent principle and aromatic substance having a heat-generating effect, preferably in preparations used for foodstuffs, oral hygiene or luxury foodstuffs.
摘要翻译：本发明描述了一种生产2E，4Z-癸二烯酸-N-异丁酰胺（顺式 - 效应）的方法及其作为刺激原理的用途和具有发热效果的芳香物质，优选用于食品制剂，口腔卫生或豪华食品。

10. 发明申请

US20050208084A1 Use of alkylamidomandelates as flavourings 审中-公开
标题翻译：使用烷基酰氨基扁桃酸酯作为调味剂
公开(公告)号：US20050208084A1
公开(公告)日：2005-09-22
申请号：US10517197
申请日：2003-06-14
申请人： Jakob Ley , Gerhard Krammer , Arnold Machinek
发明人： Jakob Ley , Gerhard Krammer , Arnold Machinek
IPC分类号： A23L27/20 , A61K8/42 , A61Q11/00 , C07C235/34 , A61K31/165 , A61K7/00
CPC分类号： A61K8/42 , A23L27/204 , A61Q11/00 , C07C235/34
摘要： The present invention describes various mandelic acid alkylamides and their use as pungent compounds and flavour compounds with a heat-generating effect, preferably in preparations for use in nutrition, oral hygiene or consumed for pleasure.
摘要翻译：本发明描述了各种扁桃酸烷基酰胺及其作为刺激性化合物和具有发热效果的风味化合物的用途，优选用于营养，口腔卫生或消费用于快乐的制剂。

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