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1. 发明授权

US06554982B1 Miniaturized solid-state reference electrode with self-diagnostic function 失效
标题翻译：具有自诊断功能的小型化固态参比电极
公开(公告)号：US06554982B1
公开(公告)日：2003-04-29
申请号：US09889032
申请日：2001-07-12
申请人： Jae Ho Shin , Sung Dong Lee , Hakhyun Nam , Geun Sig Cha , Byeong Woo Bae
发明人： Jae Ho Shin , Sung Dong Lee , Hakhyun Nam , Geun Sig Cha , Byeong Woo Bae
IPC分类号： G01N27401
CPC分类号： G01N27/301
摘要： The present invention relates to a reference electrode for a potentiometric electrode system, characterized in that the junction in contact with a sample solution is enlarged and an ion-sensitive membrane containing an ion selective material as a protective membrane for the inner reference solution is employed, which comprises a substrate; a metal layer; an insoluble metal salt layer; an insulating film for insulating the metal layer from an aqueous solution; a hydrogel serving as an inner reference solution; the junction on the hydrogel contacting with a sample solution; the ion-sensitive, protective membrane formed over all surface areas of the hydrogel, except for the junction, to separate the sample solution from the inner reference solution or act as an ion-sensing membrane upon the contamination of the junction, whereby the operational abnormality caused by junction contamination may be easily checked and fast activation may be achieved.
摘要翻译：本发明涉及一种用于电位电极系统的参考电极，其特征在于，与样品溶液接触的接合点被扩大，并且使用含有作为内部参比溶液的保护膜的离子选择性材料的离子敏感膜，其包括基底; 金属层; 不溶性金属盐层; 用于将金属层与水溶液绝缘的绝缘膜; 作为内参照溶液的水凝胶; 水凝胶上的接头与样品溶液接触; 在水凝胶的所有表面区域之外形成的离子敏感的保护膜除了接合部分之外，以将样品溶液与内部参考溶液分离，或者当接合部被污染时用作离子感测膜，由此操作异常可以容易地检查结点污染引起的并且可以实现快速激活。

2. 发明授权

US06793789B2 Reference electrode with a polymeric reference electrode membrane 失效
标题翻译：具有聚合物参比电极膜的参比电极
公开(公告)号：US06793789B2
公开(公告)日：2004-09-21
申请号：US09960432
申请日：2001-09-22
申请人： Yong Suk Choi , Sung Dong Lee , Seong Hee Oh , Hyo Lin Lee , Jae Ho Shin , Jeonghan Ha , Hakhyun Nam , Geun Sig Cha
发明人： Yong Suk Choi , Sung Dong Lee , Seong Hee Oh , Hyo Lin Lee , Jae Ho Shin , Jeonghan Ha , Hakhyun Nam , Geun Sig Cha
IPC分类号： G01N2731
CPC分类号： G01N27/301
摘要： Disclosed is a polymeric reference electrode membrane comprising (a) one selected from a porous polymer or a hydrophilic plasticizer; (b) a lipophilic polymer; and optionally an adhesion-enhancing material. A reference electrode equipped with the polymeric reference electrode membrane can be shortened the preconditioning time, and extended lifetime for storage and use owing to excellent adhesion, and showed reproducibility and good yield. So, a miniaturized multi-potentiometric sensor can be fabricated comprising a solid-state reference electrode of the present invention and a set of ion-selective electrodes, thus being useful in the potentiometric fields, including clinical, environmental, food and industrial analysis.
摘要翻译：公开了一种聚合物参比电极膜，其包含（a）选自多孔聚合物或亲水性增塑剂中的一种; （b）亲脂性聚合物; 和任选的粘附增强材料。配备有聚合物参比电极膜的参比电极可以缩短预处理时间，并且由于优异的粘附性而延长存储和使用寿命，并且显示出重现性和良好的产率。因此，可以制造包括本发明的固态参考电极和一组离子选择性电极的小型化多电位传感器，因此可用于电位计领域，包括临床，环境，食品和工业分析。

3. 发明授权

US07678261B2 Apparatus and method for measuring reaction result of samples on biosensor 有权
标题翻译：用于测量样品在生物传感器上的反应结果的装置和方法
公开(公告)号：US07678261B2
公开(公告)日：2010-03-16
申请号：US10528187
申请日：2002-10-04
申请人： Byung Woo Bae , Heon-Kwon Lee , Sung Dong Lee , Won Dong Kim , Jung Shik Song , Jin-A Yoo
发明人： Byung Woo Bae , Heon-Kwon Lee , Sung Dong Lee , Won Dong Kim , Jung Shik Song , Jin-A Yoo
IPC分类号： G01N33/50 , G01N27/327 , C12Q1/54 , C12Q1/26
CPC分类号： G01N27/3274 , G01N27/3273
摘要： Disclosed are an apparatus and a method for determining whether or not a biosensor comprising two working electrodes and one reference electrode is well manufactured, and for rapidly and accurately quantifying a specific substance contained in a biological sample. The method comprises the steps of: sequentially supplying the respective working electrodes with power supply voltage; sequentially detecting the amounts of current flowing in the respective working electrodes by virtue of the supplied power supply voltage; re-supplying the two working electrodes with power supply voltage after a predetermined time to redetect the amounts of current flowing in the respective working electrodes; reading concentrations corresponding to the amounts of current detected from a memory, and calculating an average value from the read concentrations; and checking whether or not the concentrations read from memory are within a predetermined critical range to display an error message or the calculated average value.
摘要翻译：公开了一种用于确定包括两个工作电极和一个参比电极的生物传感器是否良好制造的装置和方法，并且用于快速和准确地定量生物样品中包含的特定物质。该方法包括以下步骤：向相应的工作电极依次提供电源电压; 通过提供的电源电压依次检测在各个工作电极中流动的电流量; 在预定时间之后将两个工作电极重新供应电源电压以重新检测在各个工作电极中流动的电流量; 读取与存储器检测到的电流量相对应的浓度，并根据读取的浓度计算平均值; 并且检查从存储器读取的浓度是否在预定的临界范围内，以显示错误消息或所计算的平均值。

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