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1. 发明申请

US20070053992A1 Inhalable gaseous medicament based on xenon and nitrous oxide 审中-公开
标题翻译：基于氙气和一氧化二氮的可吸入气体药物
公开(公告)号：US20070053992A1
公开(公告)日：2007-03-08
申请号：US10563278
申请日：2004-07-23
申请人： Jacques Abraini , Marc Lemaire
发明人： Jacques Abraini , Marc Lemaire
IPC分类号： A61K33/00
CPC分类号： A61K33/00 , A61K2300/00
摘要： The invention concerns the use of a gaseous mixture containing gas xenon and gas nitrous oxide, and advantageously oxygen, for making all or part of an inhalable medicine for preventing or treating neurointoxication in a human. The xenon/nitrous oxide mixture of the invention acts on one or more cerebral receptors to reduce the release and/or the effects of dopamine, glutamate, serotonin, taurin, GABA, noradrenaline and/or any other neurotransmitter. The proportion by volume of xenon of the mixture ranges between 5 and 45%, and the proportion by volume of nitrous oxide ranges between 10 and 50%, the balance is preferably oxygen.
摘要翻译：本发明涉及使用含有气体氙气和一氧化二氮气体以及有利地为氧气的气体混合物，用于制备用于预防或治疗人类神经毒素的全部或部分可吸入药物。本发明的氙/一氧化二氮混合物作用于一种或多种脑受体，以减少多巴胺，谷氨酸，血清素，牛磺酸，GABA，去甲肾上腺素和/或任何其他神经递质的释放和/或作用。混合物的氙的体积比例为5〜45％，一氧化二氮的体积比为10〜50％，余量优选为氧。

2. 发明申请

US20050152988A1 Argon-based inhalable gaseous medicinal product for the treatment of neurointoxications 审中-公开
标题翻译：氩气可吸入气体药物治疗神经毒素
公开(公告)号：US20050152988A1
公开(公告)日：2005-07-14
申请号：US11007684
申请日：2004-12-08
申请人： Marc Lemaire , Jacques Abraini
发明人： Marc Lemaire , Jacques Abraini
IPC分类号： A61K33/00 , C01B23/00
CPC分类号： A61K33/00
摘要： The invention relates to the use of argon (Ar) gas for producing all or part of an inhalable medicinal product intended to prevent or treat a neurointoxication in humans. The medicinal product contains argon in an effective proportion and acts on at least one brain receptor in order to regulate the functioning of dopamine-, glutamate-, serotonin-, acetylcholine-, taurine-, GABA- and/or noradrenalin-mediated neuro-transmission systems. Preferably, the proportion by volume of argon in the gaseous medicinal product is between 15 and 80%. The neurointoxication is chosen from excitotoxicities engendering a state of addiction, acute cerebral accidents, neurodegenerative diseases, and psychiatric or neurological pathologies, in particular anxiety conditions, psychotic conditions, in particular schizophrenia, and epilepsy in its various forms.
摘要翻译：本发明涉及氩（Ar）气用于生产旨在预防或治疗人类神经毒素的全部或部分可吸入药物的用途。药用产品含有有效比例的氩气，作用于至少一种脑受体，以调节多巴胺，谷氨酸，5-羟色胺，乙酰胆碱，牛磺酸，GABA和/或去甲肾上腺素介导的神经传递的功能系统。优选地，气态医药产品中的氩气体积比例为15-80％。神经排毒选自产生成瘾状态，急性脑意外，神经变性疾病，精神病学或神经病理学，特别是焦虑症，精神病状况，特别是精神分裂症和各种形式的癫痫的兴奋性毒性。

3. 发明申请

US20070275089A1 Argon-based inhalable gaseous medicinal product for the treatment of neurointoxications 审中-公开
标题翻译：氩气可吸入气体药物治疗神经毒素
公开(公告)号：US20070275089A1
公开(公告)日：2007-11-29
申请号：US11836536
申请日：2007-08-09
申请人： Marc Lemaire , Jacques Abraini
发明人： Marc Lemaire , Jacques Abraini
IPC分类号： A61K33/00 , A61P43/00
CPC分类号： A61K33/00
摘要： The invention relates to the use of argon gas for producing all or part of an inhalable medicinal product intended to prevent or treat a neurointoxication in humans. The medicinal product contains argon in an effective proportion and acts on at least one brain receptor in order to regulate the functioning of dopamine-, glutamate-, serotonin-, acetylcholine-, taurine-, GABA- and/or noradrenalin-mediated neurotransmission systems. Preferably, the proportion by volume of argon in the gaseous medicinal product is between 15 and 80%. The neurointoxication is chosen from excitotoxicities engendering a state of addiction, acute cerebral accidents, neurodegenerative diseases, and psychiatric or neurological pathologies, in particular anxiety conditions, psychotic conditions, in particular schizophrenia, and epilepsy in its various forms.
摘要翻译：本发明涉及使用氩气来生产旨在预防或治疗人类神经毒素的全部或部分可吸入药物。药用产品含有有效比例的氩气，并且作用于至少一种脑受体，以调节多巴胺，谷氨酸，5-羟色胺，乙酰胆碱，牛磺酸，GABA和/或去甲肾上腺素介导的神经传递系统的功能。优选地，气态医药产品中的氩气体积比例为15-80％。神经排毒选自产生成瘾状态，急性脑意外，神经变性疾病，精神病学或神经病理学，特别是焦虑症，精神病状况，特别是精神分裂症和各种形式的癫痫的兴奋性毒性。

4. 发明申请

US20090252816A1 Inhalable Gaseous Medicament Based On Xenon And Nitrous Oxide 审中-公开
标题翻译：基于氙气和一氧化二氮的可吸入气体药物
公开(公告)号：US20090252816A1
公开(公告)日：2009-10-08
申请号：US12417087
申请日：2009-04-02
申请人： Jacques Abraini , Marc Lemaire
发明人： Jacques Abraini , Marc Lemaire
IPC分类号： A61K33/00
CPC分类号： A61K33/00 , A61K2300/00
摘要： The invention concerns the use of a gaseous mixture containing gas xenon and gas nitrous oxide, and advantageously oxygen, for making all or part of an inhalable medicine for preventing or treating neurointoxication in a human. The xenon/nitrous oxide mixture of the invention acts on one or more cerebral receptors to reduce the release and/or the effects of dopamine, glutamate, serotonin, taurin, GABA, noradrenaline and/or any other neurotransmitter. The proportion by volume of xenon of the mixture ranges between 5 and 45%, and the proportion by volume of nitrous oxide ranges between 10 and 50%, the balance is preferably oxygen.
摘要翻译：本发明涉及使用含有气体氙气和一氧化二氮气体以及有利地为氧气的气体混合物，用于制备用于预防或治疗人类神经毒素的全部或部分可吸入药物。本发明的氙/一氧化二氮混合物作用于一种或多种脑受体，以减少多巴胺，谷氨酸，血清素，牛磺酸，GABA，去甲肾上腺素和/或任何其他神经递质的释放和/或作用。混合物的氙的体积比例为5〜45％，一氧化二氮的体积比为10〜50％，余量优选为氧。

5. 发明申请

US20150148455A1 DISPERSING POLYMERS WITH IMPROVED THERMAL STABILITY 有权
标题翻译：具有改进的热稳定性的分散聚合物
公开(公告)号：US20150148455A1
公开(公告)日：2015-05-28
申请号：US14238190
申请日：2012-08-09
申请人： Alexandre Desseroir , Philippe Maitrasse , Marc Lemaire , Florence Popowycz , PIERRE Labourt-Ibarre
发明人： Alexandre Desseroir , Philippe Maitrasse , Marc Lemaire , Florence Popowycz , PIERRE Labourt-Ibarre
IPC分类号： C04B24/26 , C08J3/12 , C08F120/06
CPC分类号： C04B24/2647 , C04B24/2658 , C04B2103/006 , C04B2103/408 , C04B2103/52 , C08F8/14 , C08F8/30 , C08F8/32 , C08F120/06 , C08F2220/285 , C08G81/025 , C08J3/12 , C08J3/21 , C08J2333/02 , C08J2333/04 , C08J2333/06 , C08K5/005 , C08K5/18
摘要： The invention relates mainly to a polymer comprising a hydrocarbon-based main chain bearing carboxylic groups and polyalkoxylated chains and up to 4% by weight of anti-oxidant groups, relative to the weight of the final polymer, grafted to the main chain. It also relates to a method for preparing such a polymer and to an admixture which is of use as a plasticizer of suspensions of mineral particles comprising same. Finally, it is related to the use of such a polymer for fluidifying suspensions of mineral particles and reducing the water demand of hydraulic compositions.
摘要翻译：本发明主要涉及一种聚合物，其包含相对于接枝到主链上的最终聚合物重量的含有羧基和聚烷氧基化链的烃基主链和最多达4重量％的抗氧化剂基团的聚合物。它还涉及一种制备这种聚合物的方法和一种混合物，其可用作包含其的矿物颗粒的悬浮液的增塑剂。最后，它涉及使用这种聚合物来流化矿物颗粒的悬浮液并降低水硬性组合物的用水需求。

6. 发明申请

US20130165693A1 PROCESS FOR PREPARING 4-AMINO-5-HEXENOIC ACID AND INTERMEDIATES THEREOF 审中-公开
标题翻译：制备4-氨基-5-十六酸的方法及其中间体
公开(公告)号：US20130165693A1
公开(公告)日：2013-06-27
申请号：US13531480
申请日：2012-06-22
申请人： Hugues BIENAYME , Florence Popowyce , Marc Lemaire , Marie-Christine Duclos
发明人： Hugues BIENAYME , Florence Popowyce , Marc Lemaire , Marie-Christine Duclos
IPC分类号： C07C229/30 , C07C227/22
CPC分类号： C07C227/22 , A61K31/197 , C07C229/30
摘要： The present invention relates to a new and competitive process for the preparation of 4-amino-5-hexenoic acid and intermediates thereof. The compound, and compositions containing the compound as an active ingredient, can be used for the treatment and/or prophylaxis of epilepsy and West syndrome.
摘要翻译：本发明涉及一种制备4-氨基-5-己烯酸的新型竞争方法及其中间体。该化合物和含有化合物作为活性成分的组合物可用于治疗和/或预防癫痫和西综合征。

7. 发明授权

US07641799B2 Method of separating isotopes 有权
标题翻译：分离同位素的方法
公开(公告)号：US07641799B2
公开(公告)日：2010-01-05
申请号：US11986402
申请日：2007-11-21
申请人： Marc Lemaire , Jacques Foos , Alain Guy , Frédéric Chitry , Stéphane Pellet-Rostaing , Olivier Vigneau
发明人： Marc Lemaire , Jacques Foos , Alain Guy , Frédéric Chitry , Stéphane Pellet-Rostaing , Olivier Vigneau
IPC分类号： B01D61/00 , C01F17/00 , C01F13/00
CPC分类号： B01J45/00 , B01D59/22 , B01D59/30 , C07C237/04 , Y10S423/07
摘要： A process in which isotopes of the same element belonging to the alkaline earth metals, transition elements and heavy metals having an atomic mass of less than 209, in particular lanthanide metals, are separated in an aqueous medium by treating an aqueous medium.
摘要翻译：通过处理水性介质，在水性介质中分离属于碱土金属，过渡元素和原子质量小于209的重金属，特别是镧系元素的同质元素的同位素。

8. 发明申请

US20090117018A9 Process for the Separation and Purification of Hafnium and Zirconium 有权
标题翻译：铪和锆的分离和纯化方法
公开(公告)号：US20090117018A9
公开(公告)日：2009-05-07
申请号：US11632021
申请日：2005-07-07
申请人： Laurence Delons , Stephane Lagarde , Alain Favre-Reguillon , Stephane Pellet-Rostaing , Marc Lemaire , Ludovic Poriel
发明人： Laurence Delons , Stephane Lagarde , Alain Favre-Reguillon , Stephane Pellet-Rostaing , Marc Lemaire , Ludovic Poriel
IPC分类号： C01G25/00 , C01G27/00 , C22B3/00
CPC分类号： C01G25/04 , C01G25/003 , C01G27/003 , C01G27/04
摘要： A process for the separation and purification of hafnium and zirconium.
摘要翻译：一种分离和纯化铪和锆的方法。

9. 发明申请

US20080031791A1 Process for the Separaton of Hafnium and Zirconium 有权
标题翻译：铪和锆的分离方法
公开(公告)号：US20080031791A1
公开(公告)日：2008-02-07
申请号：US11632021
申请日：2005-07-07
申请人： Laurence Delons , Stephane Lagarde , Alain Favre-Reguillon , Stephane Pellet-Rostaing , Marc Lemaire , Ludovic Poriel
发明人： Laurence Delons , Stephane Lagarde , Alain Favre-Reguillon , Stephane Pellet-Rostaing , Marc Lemaire , Ludovic Poriel
IPC分类号： C01G25/00 , C01G27/00 , C22B3/00
CPC分类号： C01G25/04 , C01G25/003 , C01G27/003 , C01G27/04
摘要： A process for the separation and purification of hafnium and zirconium.
摘要翻译：一种分离和纯化铪和锆的方法。

10. 发明授权

US06441264B1 Method for separating benzothiophene compounds from hydrocarbon mixture containing them, and hydrocarbon mixture obtained by said method 失效
标题翻译：从含有它们的烃混合物中分离出苯并噻吩化合物的方法和通过所述方法得到的烃混合物
公开(公告)号：US06441264B1
公开(公告)日：2002-08-27
申请号：US09445369
申请日：2000-04-17
申请人： Marc Lemaire , Michéle Monnet , Michel Vrinat , Valérie Lamure , Emmanuelle Sanson , Alexandra Milenkovic
发明人： Marc Lemaire , Michéle Monnet , Michel Vrinat , Valérie Lamure , Emmanuelle Sanson , Alexandra Milenkovic
IPC分类号： C10G2922
CPC分类号： C10G29/20
摘要： A method for separating at least a benzothiophene compound from a hydrocarbon mixture is disclosed. The method includes contacting the mixture of a fraction obtained therefrom with a reagent including an acceptor complexing agent &pgr;, to obtain a donor-acceptor complex between the acceptor complexing agent and the benzothiophene compound; and separating the complex from the mixture, or from the fraction, to obtain a fraction depleted or purified in the benzothiophene compound.
摘要翻译：公开了从烃混合物中分离出至少苯并噻吩化合物的方法。该方法包括将得自其的级分的混合物与包含受体络合剂pi的试剂接触，以获得受体络合剂和苯并噻吩化合物之间的供体 - 受体复合物; 并从该混合物或该馏分中分离该复合物，得到在苯并噻吩化合物中贫化或纯化的馏分。

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