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1. 发明专利

HK1089706A1 CONTAINER FOR SERUM PRODUCTION AND METHOD OF REGENERATIVE MEDICINE USING THE SAME 未知
公开(公告)号：HK1089706A1
公开(公告)日：2006-12-08
申请号：HK06109923
申请日：2006-09-06
申请人： JMS CO LTD
发明人： SUZUKI KOJI , FUJII JUNYA , MATSUURA MARI , TANAKA SEISHIN , KONDO KEN
IPC分类号： A61B5/15 , A61K35/14 , A61K35/15 , A61K35/16 , A61K35/18 , A61M20100101 , A61M1/02 , A61P7/00 , A61P43/00 , C12M1/00 , C12N5/07 , C12N5/074 , G01N20100101 , G01N33/48
摘要： A blood storage container suitable for quick and efficient production of a large amount of serum while ensuring high safety, and a method of separating blood and a regenerative medical process using the same are provided. In a blood component separator 1 for separating collected blood into a plurality of blood components and preserving them, the separator 1 including a blood reservoir 10 for reserving the blood and a component storage part 20 aseptically connected in an air-tight manner to this blood reservoir 10, to the aforementioned blood reservoir 10 being imparted a serum producing function to remove coagulation factors from the blood to an extent enabling use in practical applications as a serum, and the aforementioned component storage part 20 storing each blood component generated by separation of the blood in the blood reservoir 10.

2. 发明专利

JP2007185534A Container for serum production and method of regenerative medicine using the same 有权
标题翻译：用于血清生产的容器和使用该方法的再生医学方法
公开(公告)号：JP2007185534A
公开(公告)日：2007-07-26
申请号：JP2007093089
申请日：2007-03-30
申请人： Jms Co Ltd , 株式会社ジェイ・エム・エス
发明人： SUZUKI KOJI , FUJII JUNYA , MATSUURA MARI , TANAKA SEISHIN
IPC分类号： A61M1/02 , A61J1/05
摘要： PROBLEM TO BE SOLVED: To provide a blood storage container which is suitable for a quick and efficient production of a large amount of serum while ensuring a high safety, and methods of separating blood and of regenerative medicine. SOLUTION: A blood component separator 1 for separating collected blood into a plurality of blood components and preserving them includes a blood reservoir 10 for accumulating the blood and a component storage part 20 aseptically connected to the blood reservoir 10 in an air-tight manner. The blood reservoir 10 has a serum producing function to remove coagulation factors from the blood to an extent to use the blood practically as a serum, and the component storage part 20 stores each blood component generated by separating the blood in the blood reservoir 10. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：解决问题：提供一种适合快速有效地生产大量血清同时确保高度安全性的血液储存容器以及分离血液和再生药物的方法。解决方案：用于将收集的血液分离成多个血液成分并保存的血液成分分离器1包括用于积聚血液的血液储存器10和以气密方式与血液储存器10无菌连接的部件收纳部20 方式。血液储存器10具有血清产生功能，以从血液中除去血液中的凝血因子，实际上作为血清使用血液，成分存储部20存储通过将血液分离而生成的血液成分。 P>版权所有（C）2007，JPO＆INPIT

3. 发明公开

EP1625861A4 CONTAINER FOR SERUM PRODUCTION AND METHOD OF REGENERATIVE MEDICINE USING THE SAME 审中-公开
标题翻译：集装箱血清生产和本程序使用了再生医学
公开(公告)号：EP1625861A4
公开(公告)日：2012-04-11
申请号：EP04734398
申请日：2004-05-21
申请人： JMS CO LTD
发明人： SUZUKI KOJI , FUJII JUNYA , MATSUURA MARI , TANAKA SEISHIN , KONDO KEN
IPC分类号： A61M1/02 , A61K35/14 , G01N33/48
CPC分类号： A61M1/0209 , A61M1/0218 , A61M1/0231 , A61M1/029 , A61M2202/0014 , A61M2202/0415

4. 发明专利

JP2010189415A Separation instrument 有权
标题翻译：分离仪
公开(公告)号：JP2010189415A
公开(公告)日：2010-09-02
申请号：JP2010091281
申请日：2010-04-12
申请人： Jms Co Ltd , 株式会社ジェイ・エム・エス
发明人： SUZUKI KOJI , FUJII JUNYA , MATSUURA MARI , TANAKA SEISHIN
IPC分类号： A61K35/14 , A61K35/16 , A61M1/02 , A61P7/00 , A61P43/00
CPC分类号： A61M1/0209 , A61M1/0218 , A61M1/0231 , A61M1/029 , A61M2202/0014 , A61M2202/0415
摘要： PROBLEM TO BE SOLVED: To provide an apparatus for blood components separation, imparted with a serum forming function to give a practically applicable amount of serum by a coagulation and activation actions in the presence of liquid components and platelets derived from blood. SOLUTION: The separation instrument is equipped with a flexible bag and a blood coagulation stimulating substance stored in the bag body and used for a blood coagulation stimulating vessel accelerating formation of serum by storing blood in the bag body having a pair of pinching pieces capable of pinching the bag body from its outside and a connecting part connecting the pair of pinching pieces at respective one end so as to openable and closable each other the pair of pinching pieces without allowing passing through of the blood coagulation stimulating substance to an opposite plane of the pair of pinching pieces under closed state, and forming a separating distance capable of passing through a cleaning solution of erythrocytes and fibrin. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供一种用于血液成分分离的装置，赋予血清形成功能，通过在来自血液的液体成分和血小板的存在下通过凝血和活化作用产生实际适用量的血清。解决方案：分离装置配备有存储在袋体中的柔性袋和凝血物质，用于通过将血液储存在具有一对夹紧片的袋体中而促进血液形成的凝血刺激容器能够从其外侧夹持袋体，以及连接部，其将一对夹持片在相应的一端连接，从而能够使一对夹持片彼此打开和关闭，而不允许将凝血刺激物质通过到相对的平面并且形成能够通过红细胞和纤维蛋白的清洁溶液的分离距离。版权所有（C）2010，JPO＆INPIT

5. 发明专利

JP2007196011A Container for serum production and method of regenerative medicine using the same 有权
标题翻译：用于血清生产的容器和使用该方法的再生医学方法
公开(公告)号：JP2007196011A
公开(公告)日：2007-08-09
申请号：JP2007093086
申请日：2007-03-30
申请人： Jms Co Ltd , 株式会社ジェイ・エム・エス
发明人： SUZUKI KOJI , FUJII JUNYA , MATSUURA MARI , TANAKA SEISHIN
IPC分类号： A61M1/02 , A61K35/14 , A61P7/00 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide a blood accommodation container suitable for speedy and efficient production of a large volume of serum while ensuring high safety, and a method of blood separation and a method of regenerative medicine using the blood accommodation container. SOLUTION: A blood constituent separator 1 for separating collected blood into multiple blood constituents and storing, is equipped with a blood storing unit 10 for storing the blood, and a constituent accommodation units 20 aseptically and hermetically connected to the blood storing unit 10. The blood storing unit 10 is provided with serum producing function capable of removing coagulation factors from the blood to such an extent that practical use as the serum can be realized, and the constituent accommodation units 20 accommodate blood constituents resulting from separation of the blood effected in the blood storing unit 10. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供适合于快速高效地生产大量血清同时确保高安全性的血液容纳容器，以及血液分离方法和使用血液容纳容器的再生药物的方法。解决方案：用于将收集的血液分离成多个血液成分并储存的血液成分分离器1配备有用于储存血液的血液存储单元10和无菌和气密地连接到血液存储单元10的成分收纳单元20 血液存储单元10具有能够从血液中除去凝血因子的血清生成功能，使得能够实现作为血清的实际用途的程度，并且构成容纳单元20容纳由血液分离产生的血液成分在血液存储单元10中。（C）2007，JPO＆INPIT

6. 发明专利

JP2010227582A Serum preparing device 有权
标题翻译：血清制剂装置
公开(公告)号：JP2010227582A
公开(公告)日：2010-10-14
申请号：JP2010091280
申请日：2010-04-12
申请人： Jms Co Ltd , 株式会社ジェイ・エム・エス
发明人： SUZUKI KOJI , FUJII JUNYA , MATSUURA MARI , TANAKA SEISHIN
IPC分类号： A61M1/02 , A61K35/16 , A61L27/00 , C12M1/00
CPC分类号： A61M1/0209 , A61M1/0218 , A61M1/0231 , A61M1/029 , A61M2202/0014 , A61M2202/0415
摘要： PROBLEM TO BE SOLVED: To provide a blood component separator having a serum forming function which forms serum in an amount practically used in the presence of a liquid component and platelets originating from the blood by coagulation activating action. SOLUTION: This serum preparing device includes a blood coagulation accelerating container, a blood component lead-out passage connected to the blood coagulation accelerating container on one end side thereof, a serum preserving container connected to the other end of the blood component lead-out passage and a serum separating filter provided to the blood component lead-out passage and having a large number of pores not permitting blood corpuscle components to pass but permitting the serum to pass. The blood coagulation accelerating container is constituted of a flexible bag. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供一种具有血清形成功能的血液成分分离器，该血液成分分离器通过凝血活化作用在液体成分和血液中存在的实际使用的量形成血清。解决方案：该血清制备装置包括凝血促进容器，在其一端侧与血液凝固促进容器连接的血液成分引出通道，与血液成分铅的另一端连接的血清保存容器提供给血液成分引出通道的血清分离过滤器，并且具有大量不允许血球成分通过但允许血清通过的孔。凝血促进容器由柔性袋构成。版权所有（C）2011，JPO＆INPIT

7. 发明专利

JP2010222376A Serum preparation apparatus 有权
标题翻译：血清制剂装置
公开(公告)号：JP2010222376A
公开(公告)日：2010-10-07
申请号：JP2010138703
申请日：2010-06-17
申请人： Jms Co Ltd , 株式会社ジェイ・エム・エス
发明人： SUZUKI KOJI , FUJII JUNYA , MATSUURA MARI , TANAKA SEISHIN
IPC分类号： A61K35/16 , A61M1/02
CPC分类号： A61M1/0209 , A61M1/0218 , A61M1/0231 , A61M1/029 , A61M2202/0014 , A61M2202/0415
摘要： PROBLEM TO BE SOLVED: To provide a serum preparation apparatus suitable for quick and efficient production of a large amount of serum while ensuring high safety. SOLUTION: This serum preparation apparatus 280 includes an indwelling needle 282, a catheter 281 one end of which is connected to the base end side of the indwelling needle 282, a syringe 283 storable of blood, that is connected to the other end of the catheter 281 and blood coagulant pieces 284 contained in the syringe 283. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供适合快速高效地生产大量血清的血清制备装置，同时确保高安全性。解决方案：该血清制备装置280包括留置针282，其一端连接到留置针282的基端侧的导管281，可存储血液的注射器283，其连接到另一端导管281和包含在注射器283中的凝血块284.版权所有（C）2011，JPO＆INPIT

8. 发明专利

JP2007283093A Centrifugal separation assisting device and component separation method 有权
标题翻译：离散分离辅助装置和组件分离方法
公开(公告)号：JP2007283093A
公开(公告)日：2007-11-01
申请号：JP2007072756
申请日：2007-03-20
申请人： Jms Co Ltd , 株式会社ジェイ・エム・エス
发明人： TANAKA SEISHIN , SUZUKI KOJI , MATSUURA MARI , HIRAI SATOSHI
IPC分类号： A61M1/02
CPC分类号： B04B5/0428
摘要： PROBLEM TO BE SOLVED: To provide a centrifugal separation assisting device with general purpose performance in which device a posture of a container containing blood etc., can be controlled on centrifugal operation and a container containing blood etc., can be easily put in/out from a centrifugal holder. SOLUTION: A centrifugal separation assisting device 10 is to be inserted into a centrifugal holder of a centrifugal separator to centrifugal-separate a liquid mixture of a plurality of components. The device 10 is equipped with a cushioning body 11 into which gas and/or liquid is sealed. The cushioning body 11 is equipped with a leading in/out part 12 through which gas and/or liquid is put in/out from the inside thereof. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：为了提供具有通用性能的离心分离辅助装置，其中可以容易地放置装置中含有血液等的容器的姿势以及离心操作的容器和容纳血液的容器等从离心支架进出。解决方案：将离心分离辅助装置10插入到离心分离器的离心保持器中以离心分离多个部件的液体混合物。装置10配备有缓冲体11，气体和/或液体被密封在该缓冲体11中。缓冲体11配备有从内部输入/排出气体和/或液体的前进/后出部分12。版权所有（C）2008，JPO＆INPIT

9. 发明专利

JP2011162547A Serum preparing method 有权
标题翻译：血清制备方法
公开(公告)号：JP2011162547A
公开(公告)日：2011-08-25
申请号：JP2011053446
申请日：2011-03-10
申请人： Jms Co Ltd , 株式会社ジェイ・エム・エス
发明人： SUZUKI KOJI , FUJII JUNYA , MATSUURA MARI , TANAKA SEISHIN
IPC分类号： A61K35/16 , A61M1/02 , C12N1/00 , C12N5/071
CPC分类号： A61M1/0209 , A61M1/0218 , A61M1/0231 , A61M1/029 , A61M2202/0014 , A61M2202/0415
摘要： PROBLEM TO BE SOLVED: To provide a serum preparing method suitable for quick and efficient production of a large amount of serum while ensuring high safety. SOLUTION: There is provided a serum preparing method using a blood component separation/storage device which comprises a blood storage part storing a fluid containing a fluidic component containing at least blood-original coagulation factor and platelets and a component reservation part aseptically and airtightly connected to the blood storage part, wherein the blood storage part contains blood coagulation promotion objects brought into contact with the fluid to promote coagulation, and the blood coagulation promotion object is insoluble in the fluid and has a massive form, and which method comprises a step of bringing the fluid into contact with the blood coagulation promoting objects in the blood storage part to promote blood coagulation to prepare serum, and a step of transferring the serum prepared in the blood storage part to the component receiving part aseptically and airtightly connected with the blood storage part so as to be received therein. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供适合快速高效地生产大量血清的血清制备方法，同时确保高安全性。提供一种使用血液成分分离/储存装置的血清制备方法，该血液成分分离/储存装置包括储存含有至少含有血液原始凝血因子和血小板的流体成分的液体的血液存储部分和无菌的成分保留部分，与血液存储部气密地连接，其中，血液存储部具有与流体接触的促凝血促进对象，促进凝血，血液凝固促进对象不溶于液体，具有大体形状，使流体与血液存储部中的血液凝固促进物体接触以促进血液凝固以制备血清的步骤，以及将血液存储部中制备的血清转移到与无菌和气密连接的部件接收部分的步骤血液储存部，以便容纳在其中。版权所有（C）2011，JPO＆INPIT

10. 发明专利

JP2007275561A Component storing section supporting device 有权
标题翻译：组件存储部分支持的设备
公开(公告)号：JP2007275561A
公开(公告)日：2007-10-25
申请号：JP2007063745
申请日：2007-03-13
申请人： Jms Co Ltd , 株式会社ジェイ・エム・エス
发明人： TANAKA SEISHIN , SUZUKI KOJI , MATSUURA MARI , TACHIBANA HIROKO
IPC分类号： A61M1/02
摘要： PROBLEM TO BE SOLVED: To subdivide predetermined components in a blood storing section into a plurality of component storing sections in an equal quantity and without remaining air inside of them.
SOLUTION: A component storing section supporting device has a separating device 1 having a blood collecting bag 100 storing a blood component, a plurality of preparative bags 200, and a controlling bag 300, connecting tubes connecting the bags 100, 200, 300, a pressurizing device 3 pressurizing the blood collecting bag 100, and a supporting device 4 supporting each preparative bag 200, the preparative bags 200 are located in the lower side of the blood collecting bag 100, a blood serum component in the blood collecting bag 100 is moved to each preparative bags 200 by the pressure generated by the pressurizing force applied to the blood collecting bag 100 and the head, and the blood serum component is collected from the blood collecting bag 100 and subdivided into each preparative bag 200, the component storing section supporting device 4 has a fixed plate 41 and a movable plate 42, each preparative bag 200 is set onto the fixed plate 41, and the movable plate simultaneously presses the plurality of preparative bags 200 by the same pressure.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：将血液存储部分中的预定组分细分成多个组分存储部分，并且没有剩余空气。解决方案：组件存储部分支持装置具有分离装置1，其具有存储血液成分的采血袋100，多个制备袋200和控制袋300，连接管100,200,300的连接管，对集血袋100进行加压的加压装置3以及支撑各制袋200的支承装置4，制袋200位于集血袋100的下侧，血液收集袋100内的血清成分通过施加到采集袋100和头部的加压力产生的压力移动到每个制备袋200，并且将血清成分从采集袋100收集并分成各个制备袋200，存储部件区段支撑装置4具有固定板41和可移动板42，将每个制袋200设置在固定板41上，并且可移动板同时按压多个制备袋200通过相同的压力。版权所有（C）2008，JPO＆INPIT

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