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1. 发明申请

US20120260355A1 Method for Evaluating Inhibitory Polynucleotide Efficiency and Efficacy 审中-公开
标题翻译：评估抑制性多核苷酸效率和疗效的方法
公开(公告)号：US20120260355A1
公开(公告)日：2012-10-11
申请号：US13517094
申请日：2010-12-22
申请人： Ira S. Cohen , Thomas W. White , Richard B. Robinson , Peter R. Brink , Richard T. Mathias , Michael R. Rosen
发明人： Ira S. Cohen , Thomas W. White , Richard B. Robinson , Peter R. Brink , Richard T. Mathias , Michael R. Rosen
IPC分类号： A61K49/00
CPC分类号： G01N33/5088 , C12Q1/6897 , C12Q2525/207
摘要： The present invention provides a method for testing the efficiency of delivering an inhibitory polynucleotide to a target cell or tissue. The invention also provides a method for testing efficiency of delivering and efficacy for an effect on tumor size of an inhibitory polynucleotide against a target gene.
摘要翻译：本发明提供了一种用于测试将抑制性多核苷酸递送至靶细胞或组织的效率的方法。本发明还提供了一种用于测试递送效率的方法以及对靶基因的抑制性多核苷酸对肿瘤大小的影响的效力。

2. 发明授权

US5524030A Multistage control rod drive uncoupling tool 失效
标题翻译：多级控制杆驱动解耦工具
公开(公告)号：US5524030A
公开(公告)日：1996-06-04
申请号：US199405
申请日：1994-02-22
申请人： Thomas W. White , Balasubramanian S. Kowdley , Thomas A. Lewis , Christopher J. Miller , Robert S. Tsukida , Andrew S. Wong , Thomas R. Eckmann , Edward W. Saxon , Frank Ortega
发明人： Thomas W. White , Balasubramanian S. Kowdley , Thomas A. Lewis , Christopher J. Miller , Robert S. Tsukida , Andrew S. Wong , Thomas R. Eckmann , Edward W. Saxon , Frank Ortega
IPC分类号： G21C7/16 , G21C19/20 , G21C19/00
CPC分类号： G21C7/16 , G21Y2002/40 , G21Y2002/50 , Y02E30/39
摘要： An uncoupling tool has a two-module design: one module being a driver assembly for developing the uncoupling movement and the other module being a probe assembly for verifying the uncoupled condition. The probe assembly attaches to the threaded end of the piston tube with its probe extending inside the piston tube. The driver assembly attaches to the CRD ring flange. The probe assembly detects the ring magnet in the drive piston using analog position sensors which operate on the principle of the Hall effect and solid state circuitry. A top sensor provides a signal indicating that the control rod is in its "full out" position; a bottom sensor provides a signal indicating that the control rod is uncoupled; and an intermediate sensor provides a signal indicating that the control rod is in a transition position between the "full out" and uncoupled positions. The probe incorporates spacers which focus the magnetic flux onto the sensors. To uncouple the control rod, the probe assembly is lifted using a separate driver assembly.
摘要翻译：解耦工具具有双模块设计：一个模块是用于开发非耦合运动的驱动器组件，而另一模块是用于验证非耦合状态的探针组件。探针组件连接到活塞管的螺纹端，其探针在活塞管内延伸。驱动器组件连接到CRD环形法兰。探头组件使用以霍尔效应和固态电路为原理的模拟位置传感器来检测驱动活塞中的环形磁体。顶部传感器提供指示控制杆处于其“完全”位置的信号; 底部传感器提供指示控制杆脱离的信号; 并且中间传感器提供指示控制杆处于“完全”和非耦合位置之间的过渡位置的信号。探头包含将磁通量聚焦到传感器上的间隔物。为了使控制杆脱开，探针组件使用单独的驱动器组件提升。

3. 发明授权

US5347554A Outer filter removal tool 失效
标题翻译：外滤器去除工具
公开(公告)号：US5347554A
公开(公告)日：1994-09-13
申请号：US135872
申请日：1993-10-12
申请人： Thomas W. White , Edward J. Pulpan , Robert S. Tsukida , Edward W. Saxon , Frank Ortega
发明人： Thomas W. White , Edward J. Pulpan , Robert S. Tsukida , Edward W. Saxon , Frank Ortega
IPC分类号： G21C19/20 , G21C19/00
CPC分类号： G21C19/00 , G21C19/207 , G21Y2002/301 , G21Y2002/40 , G21Y2004/50
摘要： An improved tool for removing a highly contaminated outer filter from a control rod drive during a maintenance operation. The tool slides onto the control rod drive and surrounds the outer filter with a shield. The shield has a window for removing the screws used to mount the outer filter on the control rod drive. The tool has a support for the spud on the inside thereof. A U-shaped handle is slidably inserted into guideways so that it interlocks with circumferential slots in the shield. The arms of the inserted U-handle latch underneath the ring flange of the outer filter, whereby the outer filter is captured by the tool. The filter-mounting screws are then removed by unscrewing through the aligned window in the shield. Thereafter, the outer filter is removed from the CRD when the outer filter removal tool is lifted.
摘要翻译：一种改进的工具，用于在维护操作期间从控制杆驱动器中去除高度污染的外部过滤器。该工具滑动到控制杆驱动器上，并用屏蔽件围绕外部过滤器。屏蔽罩有一个窗口用于拆卸用于将外部过滤器安装在控制杆驱动器上的螺钉。该工具在其内部具有支撑件。 U形手柄可滑动地插入导轨中，使其与屏蔽件中的周向狭槽互锁。插入的U形手柄的臂在外部过滤器的环形凸缘下方锁定，由此外部过滤器被工具捕获。然后通过拧松屏蔽中对齐的窗口拧下过滤器安装螺钉。此后，当外部过滤器去除工具被提起时，外部过滤器从CRD中移除。

4. 发明授权

US07483835B2 AD detection using ID code and extracted signature 有权
标题翻译： AD检测使用ID码和提取签名
公开(公告)号：US07483835B2
公开(公告)日：2009-01-27
申请号：US10328201
申请日：2002-12-23
申请人： Alan R. Neuhauser , Thomas W. White
发明人： Alan R. Neuhauser , Thomas W. White
IPC分类号： G10L21/00
CPC分类号： H04H20/33 , H04H20/14 , H04H60/372 , H04H60/375 , H04H60/44 , H04H60/58 , H04H2201/90
摘要： Systems and methods are provided for gathering audience measurement data relating to receipt of and/or exposure to audio data by an audience member. A signature characterizing the audio data and additional data are obtained, and the audio data is identified based on both.
摘要翻译：提供了系统和方法，用于收集与受众成员接收和/或接触音频数据有关的观众测量数据。获得表征音频数据和附加数据的签名，并且基于这两者识别音频数据。

5. 发明授权

US5379330A Inner filter removal tool 失效
标题翻译：内滤器去除工具
公开(公告)号：US5379330A
公开(公告)日：1995-01-03
申请号：US135779
申请日：1993-10-12
申请人： Robert K. Lovell , Robert S. Tsukida , Frank Ortega , Thomas W. White
发明人： Robert K. Lovell , Robert S. Tsukida , Frank Ortega , Thomas W. White
IPC分类号： G21C19/20 , G21C19/26 , G21C19/00
CPC分类号： G21C19/26 , G21C19/207 , B01D2201/24 , B01D2201/4084 , G21Y2002/402 , G21Y2004/501
摘要： An improved tool for removing the highly contaminated inner filter from a control rod drive during a maintenance operation. The tool may also be used to install the inner filter by pushing the inner filter on and locking the spring clip onto flats of the center lug of the control rod drive stop piston. The tool has a collet with flexible fingers which are inserted inside the inner filter while flexed radially inward. After the collet is inserted, a retractable cam with a conical bearing surface is retracted to a position whereat it urges the collet fingers radially outward to clamp the collet onto the inner filter. The locked filter must be rotated before removal. With the inner filter coupled to the collet, the tool is then pulled out to remove the inner filter from the control rod drive.
摘要翻译：一种改进的工具，用于在维护操作期间从控制杆驱动器中去除高度污染的内部过滤器。该工具还可以用于通过推动内部过滤器并将弹簧夹锁定到控制棒驱动停止活塞的中心凸耳的平面上来安装内部过滤器。该工具具有柔性指状物的夹头，其在径向向内弯曲的同时插入内部过滤器内部。在插入夹头之后，具有锥形支承表面的可伸缩凸轮缩回到其中径向向外推动夹头的位置，以将夹头夹紧到内部过滤器上。锁定的过滤器必须在拆卸前旋转。将内部过滤器联接到夹头上，然后将工具拉出以从控制杆驱动器中移除内部过滤器。

6. 发明授权

US07116041B2 Spark electrode assembly 失效
标题翻译：火花电极组件
公开(公告)号：US07116041B2
公开(公告)日：2006-10-03
申请号：US10855830
申请日：2004-05-27
申请人： Robert L. Burton , D. Wayne Leidy , Garrett L. Scott , Thomas W. White
发明人： Robert L. Burton , D. Wayne Leidy , Garrett L. Scott , Thomas W. White
IPC分类号： H01T13/00 , H01T13/02 , H01T13/20
CPC分类号： H01T13/20 , C03B40/027 , F23Q3/006 , H01T13/14
摘要： A spark electrode assembly has an elongate electrode with an inner insulator arranged for operable attachment to a support structure. The inner insulator surrounds the electrode with one end of the electrode positioned adjacent a ground element across a spark gap and another end of the electrode extending relative to the support structure for attachment to a source of electrical power. An outer insulator is spaced radially outwardly from the inner insulator and surrounds the inner insulator generally adjacent the end of the electrode adjacent the ground element. The inner and outer insulators cooperate to inhibit the formation of a continuous lubrication layer thereon, thereby establishing an area generally free from the lubrication layer between the end of the electrode adjacent the ground element and the support structure.
摘要翻译：火花电极组件具有细长电极，其具有布置成可操作地附接到支撑结构的内绝缘体。内绝缘体围绕电极，电极的一端通过火花隙定位在接地元件附近，并且电极的另一端相对于支撑结构延伸以附接到电力源。外绝缘体与内绝缘体径向向外间隔开，并且围绕内绝缘体大致邻近接地元件的电极端部。内绝缘体和外绝缘体配合以阻止在其上形成连续润滑层，从而在邻近接地元件的电极的端部和支撑结构之间形成通常没有润滑层的区域。

7. 发明授权

US5740035A Self-administered survey systems, methods and devices 失效
标题翻译：自我调查系统，方法和设备
公开(公告)号：US5740035A
公开(公告)日：1998-04-14
申请号：US734585
申请日：1991-07-23
申请人： Gerald B. Cohen , Louis W. Conley , Roberta M. McConochie , Robert H. Patchen , James D. Peacock , Claude A. Rankin , Thomas W. White
发明人： Gerald B. Cohen , Louis W. Conley , Roberta M. McConochie , Robert H. Patchen , James D. Peacock , Claude A. Rankin , Thomas W. White
IPC分类号： G06Q30/02 , G06F159/00
CPC分类号： G06Q30/0203 , G06Q30/02
摘要： Self-administered survey devices include a display, an input device, a memory and a control device which controls the display to show at least one survey question and control the memory to store a response to the at least one question. A system and method for carrying out self-administered surveys utilize a centralized survey data processor and a plurality of self-administered survey devices for storing survey data entered by respective respondents and wherein survey data is wirelessly transmitted from the plurality of self-administered survey devices to the centralized survey data processor.
摘要翻译：自我管理的测量设备包括显示器，输入设备，存储器和控制设备，其控制显示器以显示至少一个调查问题并控制存储器以存储对至少一个问题的响应。用于进行自我调查的系统和方法利用集中的调查数据处理器和多个自我管理的测量装置来存储由各个响应者输入的测量数据，并且其中测量数据从多个自我管理的测量装置到集中式调查数据处理器。

8. 发明授权

US5394446A Uncoupling rod centering gauge 失效
标题翻译：解耦杆定心计
公开(公告)号：US5394446A
公开(公告)日：1995-02-28
申请号：US135811
申请日：1993-10-12
申请人： Thomas W. White , Edward W. Saxon , Robert S. Tsukida
发明人： Thomas W. White , Edward W. Saxon , Robert S. Tsukida
IPC分类号： G21C19/20 , G21C7/16 , G21C17/00
CPC分类号： G21C7/16 , G21Y2002/204 , G21Y2004/304 , G21Y2004/501 , Y02E30/39
摘要： A gauge for ensuring that the uncoupling rod of a control rod drive is properly inserted in the center hole of the spud and not in one of the outer lobes, i.e., spud flow holes, which communicate with the center hole. The uncoupling rod is inserted in the spud. Then the gauge is placed on top of the spud with a centering ring protruding into the spud. The uncoupling rod is correctly installed if it is free to slide inside the gauge and the spud. The gauge is also provided with a ring to protect the spud during transfer of the control rod drive.
摘要翻译：用于确保控制棒驱动器的非耦合杆适当地插入到轴的中心孔中而不是在与中心孔连通的外凸角中的一个，即，流出孔中。分离杆插入到支脚中。然后将量规放置在立柱的顶部，并具有突出到支脚中的定心环。如果在量规和标准杆内自由滑动，则解耦杆正确安装。仪表还设有一个环，用于在控制杆传动过程中保护喷头。

9. 发明授权

US07222071B2 Audio data receipt/exposure measurement with code monitoring and signature extraction 有权
标题翻译：音频数据接收/曝光测量与代码监控和签名提取
公开(公告)号：US07222071B2
公开(公告)日：2007-05-22
申请号：US10256834
申请日：2002-09-27
申请人： Alan R. Neuhauser , Thomas W. White
发明人： Alan R. Neuhauser , Thomas W. White
IPC分类号： G10L15/00 , H04H9/00
CPC分类号： G10L15/00 , G10L19/018 , H04H60/31 , H04H60/37 , H04H60/58 , H04H60/65 , H04H2201/90
摘要： Systems and methods are provided for gathering audience measurement data relating to receipt of and/or exposure to audio data by an audience member. Audio data is monitored to detect a monitoring code. Based on detection of the monitoring code, a signature characterizing the audio data is extracted.
摘要翻译：提供了系统和方法，用于收集与受众成员接收和/或接触音频数据有关的观众测量数据。监视音频数据以检测监视码。基于监视码的检测，提取表征音频数据的签名。

10. 发明授权

US5483276A Compliance incentives for audience monitoring/recording devices 失效
标题翻译：观众监控/录音设备的合规激励
公开(公告)号：US5483276A
公开(公告)日：1996-01-09
申请号：US101558
申请日：1993-08-02
申请人： Jon R. Brooks , James M. Jensen , Roberta M. McConochie , Susan V. Osborn , Amy E. Pearl , Carole M. Schmidt , Ann B. Seiler , Carol P. Stowell , Thomas W. White , Wylie Wong
发明人： Jon R. Brooks , James M. Jensen , Roberta M. McConochie , Susan V. Osborn , Amy E. Pearl , Carole M. Schmidt , Ann B. Seiler , Carol P. Stowell , Thomas W. White , Wylie Wong
IPC分类号： H04H1/00 , H04H60/32 , H04H60/38 , H04H60/45 , H04H60/63 , H04N7/16
CPC分类号： H04H60/63 , H04N7/165 , H04H60/32 , H04H60/38 , H04H60/45
摘要： Systems and methods are provided for promoting use by an audience member of a portable broadcast exposure monitoring and/or recording device in accordance with a predetermined usage criterion. A sense signal is provided indicating whether the device is being carried with the person of the audience member, and a time signal corresponding with the sense signal is also provided. An indication to the audience member of whether the audience member's usage of the device has been in accordance with the predetermined usage criterion is provided based on the sense signal and the corresponding time signal.
摘要翻译：提供了系统和方法，用于根据预定的使用标准促进便携式广播曝光监视和/或记录装置的观众的使用。提供了一种感测信号，指示该装置是否与观众的人物携带，并且还提供了与感测信号对应的时间信号。基于感测信号和相应的时间信号，提供观众成员对于观众成员对该设备的使用情况是否符合预定使用准则的指示。

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