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1. 发明申请

WO2016176567A1 CAVITARY TISSUE ABLATION 审中-公开
标题翻译：卫生巾组织
公开(公告)号：WO2016176567A1
公开(公告)日：2016-11-03
申请号：PCT/US2016/030081
申请日：2016-04-29
申请人： INNOBLATIVE DESIGNS, INC.
发明人： RIOUX, Robert, F.
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/00083 , A61B2018/0016 , A61B2018/00238 , A61B2018/00255 , A61B2018/00267 , A61B2018/00333 , A61B2018/00452 , A61B2018/00505 , A61B2018/00529 , A61B2018/00541 , A61B2018/00547 , A61B2018/00559 , A61B2018/00577 , A61B2018/144 , A61B2018/1467 , A61B2018/1472 , A61B2218/002
摘要： The invention relates to a tissue ablation system including an ablation device having a deployable applicator head configured to be delivered to a tissue cavity and ablate marginal tissue surrounding the tissue cavity. The deployable applicator head is configured to be delivered to a tissue cavity while in a collapsed configuration and ablate marginal tissue surrounding the tissue cavity while in an expanded configuration.
摘要翻译：本发明涉及一种包括消融装置的组织消融系统，该消融装置具有可部署的施用头，其配置为被输送到组织腔并消融组织腔周围的边缘组织。可部署的施用器头构造成在处于折叠构型的同时被递送到组织腔，并且在膨胀的构型中消融围绕组织腔的边缘组织。

2. 发明申请

WO2018144090A3 ELECTROSURGICAL TISSUE AND VESSEL SEALING DEVICE 审中-公开
公开(公告)号：WO2018144090A3
公开(公告)日：2018-08-09
申请号：PCT/US2017/059850
申请日：2017-11-03
申请人： INNOBLATIVE DESIGNS, INC.
发明人： RIOUX, Robert, F.
IPC分类号： A61B18/00 , A61B18/04 , A61B18/12 , A61B18/14
摘要： An electrosurgical device can be delivered to a tissue site to provide supplemental sealing of vessels and/or vascular tissue that include suturing, stapling, or the like. The electrosurgical device is generally in the form of forceps, and includes an end effector assembly including opposing movable jaws. Each jaw includes a deformable pad or cushion including an electrode array positioned thereon. Each deformable cushion is configured to deliver a fluid, such as saline, during activation of the electrode array, thereby creating a virtual electrode which couples radiofrequency (RF) energy emitted from the electrode array into tissue in which the RF energy is converted into thermal energy. The deformable cushion and electrode array provide a controlled degree of compression upon the target tissue or vessel to maintain integrity of a suture, staple, or clip, as well as controlled energy emission for sealing, cauterizing, coagulating, and/or desiccating the target tissue or vessel.

3. 发明申请

WO2019023327A1 TISSUE ABLATION SYSTEM 审中-公开
公开(公告)号：WO2019023327A1
公开(公告)日：2019-01-31
申请号：PCT/US2018/043654
申请日：2018-07-25
申请人： INNOBLATIVE DESIGNS, INC.
发明人： RIOUX, Robert, F.
IPC分类号： A61B18/14
摘要： The present disclosure relates to a tissue ablation system including an ablation device having an expandable applicator tip configured to emit radio frequency (RF) energy for ablation and destruction of a target tissue.

4. 发明申请

WO2018144090A2 ELECTROSURGICAL TISSUE AND VESSEL SEALING DEVICE 审中-公开
公开(公告)号：WO2018144090A2
公开(公告)日：2018-08-09
申请号：PCT/US2017/059850
申请日：2017-11-03
申请人： INNOBLATIVE DESIGNS, INC.
发明人： RIOUX, Robert, F.
摘要： An electrosurgical device can be delivered to a tissue site to provide supplemental sealing of vessels and/or vascular tissue that include suturing, stapling, or the like. The electrosurgical device is generally in the form of forceps, and includes an end effector assembly including opposing movable jaws. Each jaw includes a deformable pad or cushion including an electrode array positioned thereon. Each deformable cushion is configured to deliver a fluid, such as saline, during activation of the electrode array, thereby creating a virtual electrode which couples radiofrequency (RF) energy emitted from the electrode array into tissue in which the RF energy is converted into thermal energy. The deformable cushion and electrode array provide a controlled degree of compression upon the target tissue or vessel to maintain integrity of a suture, staple, or clip, as well as controlled energy emission for sealing, cauterizing, coagulating, and/or desiccating the target tissue or vessel.

5. 发明申请

WO2018075389A1 TREATMENT DEVICES AND METHODS 审中-公开
标题翻译：治疗装置和方法
公开(公告)号：WO2018075389A1
公开(公告)日：2018-04-26
申请号：PCT/US2017/056754
申请日：2017-10-16
申请人： INNOBLATIVE DESIGNS, INC.
发明人： RIOUX, Robert, F. , HASSE, Michelle , WANKE, Tyler
IPC分类号： A61B18/00 , A61B18/14 , A61B18/08 , A61B18/10 , A61B18/12
摘要： The present invention is directed to a medical device for providing treatment to diseased tissue and cells. The medical device is configured to ablate a target tissue surface, optionally within a resection cavity, and further deliver a therapeutic that targets diseased (e.g., cancer) cells via a marker whose expression is upregulated by the ablation. The ablation directly kills diseased cells associated with the tissue surface. While some diseased cells evade direct ablation, those cells nevertheless upregulate certain cell surface markers in response to the ablation, even while other, healthy or normal cells do not upregulate expression of the marker in response to the ablation. Devices and methods disclosed herein are used to deliver a therapeutic that uses the upregulated cell surface marker to cause the death of those diseased cells.
摘要翻译：本发明涉及用于向患病组织和细胞提供治疗的医疗装置。医疗装置被配置成消融目标组织表面，任选地在切除腔内，并且进一步递送治疗剂，该治疗剂通过表达被消融上调的标记物靶向患病（例如癌症）细胞。消融直接杀死与组织表面相关的病变细胞。虽然一些患病细胞逃避直接消融，但是那些细胞响应于消融而上调某些细胞表面标记，即使当其他健康或正常细胞不响应消融时也上调了标记的表达。本文公开的装置和方法用于递送使用上调的细胞表面标志物引起那些患病细胞死亡的治疗剂。

6. 发明公开

EP3367945A1 SCREEN SPHERE TISSUE ABLATION DEVICES AND METHODS 有权
公开(公告)号：EP3367945A1
公开(公告)日：2018-09-05
申请号：EP16860886.7
申请日：2016-10-28
申请人： Innoblative Designs, Inc.
发明人： RIOUX, Robert, F. , BEAN, Ryan, M.
IPC分类号： A61B18/14 , A61B18/18
摘要： The present invention is an ablation device having a screen sphere configuration for the ablation of marginal tissue surrounding a tissue cavity. The device includes a probe having a nonconductive elongated shaft including at least one lumen therethrough and a nonconductive distal portion extending from the shaft. The nonconductive distal portion includes a plurality distal ports and a plurality of proximal ports in communication with the at least one lumen of the shaft. The device further includes an electrode array including a plurality of independent conductive wires extending through the lumen and positioned along an external surface of the nonconductive distal portion, each of the plurality of wires passes through at least an associated one of the proximal ports and through at least a corresponding one of the distal ports.

7. 发明申请

WO2022150374A1 CAVITARY TISSUE ABLATION 审中-公开
公开(公告)号：WO2022150374A1
公开(公告)日：2022-07-14
申请号：PCT/US2022/011296
申请日：2022-01-05
申请人： INNOBLATIVE DESIGNS, INC.
发明人： RZESZUTEK, Zachary , WANKE, Tyler , RIOUX, Robert, F. , BAILEY, Alyssa , KURTH, Thomas
IPC分类号： A61B18/00 , A61B18/12 , A61B18/14
摘要： The invention relates to a tissue ablation system including an ablation device having a deployable applicator, preferably, with a non-spherical head configured to be delivered to a tissue cavity and ablate marginal tissue surrounding the tissue cavity. The deployable applicator head is configured to be delivered to a tissue cavity while in a collapsed configuration and ablate marginal tissue surrounding the tissue cavity while in an expanded configuration.

8. 发明申请

WO2020236689A1 TISSUE ABLATION DEVICES AND METHODS 审中-公开
公开(公告)号：WO2020236689A1
公开(公告)日：2020-11-26
申请号：PCT/US2020/033355
申请日：2020-05-18
申请人： INNOBLATIVE DESIGNS, INC.
发明人： RIOUX, Robert, F.
IPC分类号： A61B18/14
摘要： The present invention is an ablation device having an arcuate configuration for the ablation of tissue. The device includes a probe having a nonconductive elongated shaft including at least one lumen therethrough and a nonconductive distal portion extending from the shaft. The nonconductive distal portion includes a plurality distal ports and a plurality of proximal ports in communication with the at least one lumen of the shaft. The device further includes an electrode array including a plurality of independent conductive wires extending through the lumen and positioned along an external surface of the nonconductive distal portion, each of the plurality of wires passes through at least an associated one of the proximal ports and through at least a corresponding one of the distal ports.

9. 发明申请

WO2018226839A1 SUCTION COLLAR FOR ELECTROSURGICAL DEVICES 审中-公开
公开(公告)号：WO2018226839A1
公开(公告)日：2018-12-13
申请号：PCT/US2018/036268
申请日：2018-06-06
申请人： INNOBLATIVE DESIGNS, INC.
发明人： RIOUX, Robert, F. , BEAN, Ryan, M. , WANKE, Tyler , KLIMBERG, V., Suzanne
IPC分类号： A61B18/14 , A61B17/22 , A61B17/56
摘要： The invention is an accessory configured to be fitted to an electrical surgical device and provide suction at a surgical site in which the electrical surgical device is being used. In particular, the accessory is in the form of a suction collar configured to be releasably coupled to the electrical surgical device, generally adjacent to a working end thereof, and provide suction to minimize the accumulation of excess steam, fluid, and/or debris from the surgical site during the treatment procedure. The suction collar is further configured to apply a sufficient suction force to a patient's skin surrounding the surgical site to aid in stabilizing the electrosurgical device in place and maintain the working end to the electrosurgical device within the surgical site during the procedure.

10. 发明申请

WO2018013543A1 ELECTROSURGICAL DEVICE FOR CHRONIC WOUND TREATMENT 审中-公开
标题翻译：用于慢性伤口治疗的电外科装置
公开(公告)号：WO2018013543A1
公开(公告)日：2018-01-18
申请号：PCT/US2017/041501
申请日：2017-07-11
申请人： INNOBLATIVE DESIGNS, INC.
发明人： RIOUX, Robert, F. , BEAN, Ryan, M. , WANG, Yearnchee, C.
IPC分类号： A61B18/04 , A61M25/00 , A61B18/00
摘要： The present invention relates to an electrosurgical system including an electrosurgical device to be delivered to a wound site to provide chronic wound treatment. The device can be used during a wound care procedure to provide targeted energy at a wound site for reducing the accumulation of biofilm present and removing necrotic tissue and debris so as to promote, stimulate, and stabilize the wound healing process. The device can further be used during a surgical procedure, such as preparation for an orthopedic implant, in which the device is configured to selectively coagulate one or more pockets prepared within bone tissue for holding an implant so as to prevent or stop fluid accumulation (e.g., blood from vessel(s)) as a result of the implant preparation.
摘要翻译：本发明涉及一种电外科手术系统，其包括待输送至伤口部位以提供慢性伤口治疗的电外科手术装置。该装置可在伤口护理过程中使用，以在伤口部位提供有针对性的能量，以减少存在的生物膜的积聚并去除坏死组织和碎屑，从而促进，刺激和稳定伤口愈合过程。该装置可以进一步用于外科手术期间，例如整形外科植入物的准备，其中该装置被配置为选择性地凝结在骨组织内制备的一个或多个袋以容纳植入物以防止或阻止流体积聚（例如，，来自血管的血液）作为植入物制备的结果。

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